JP2006505582A5 - - Google Patents

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Publication number
JP2006505582A5
JP2006505582A5 JP2004546290A JP2004546290A JP2006505582A5 JP 2006505582 A5 JP2006505582 A5 JP 2006505582A5 JP 2004546290 A JP2004546290 A JP 2004546290A JP 2004546290 A JP2004546290 A JP 2004546290A JP 2006505582 A5 JP2006505582 A5 JP 2006505582A5
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JP
Japan
Prior art keywords
pulmonary hypertension
combination
prostacyclin
inhalation
day
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2004546290A
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English (en)
Japanese (ja)
Other versions
JP4942297B2 (ja
JP2006505582A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/IB2003/004671 external-priority patent/WO2004037261A1/en
Publication of JP2006505582A publication Critical patent/JP2006505582A/ja
Publication of JP2006505582A5 publication Critical patent/JP2006505582A5/ja
Application granted granted Critical
Publication of JP4942297B2 publication Critical patent/JP4942297B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2004546290A 2002-10-25 2003-10-20 肺高血圧症の処置を目的としたｎ−｛５−［４−（４−メチルピペラジノメチル）−ベンゾイルアミド］−２−メチルフェニル｝−４−（３−ピリジル）−２−ピリジン−アミンの使用 Expired - Fee Related JP4942297B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42131802P 2002-10-25 2002-10-25
US60/421,318 2002-10-25
PCT/IB2003/004671 WO2004037261A1 (en) 2002-10-25 2003-10-20 Use of n-‘5-‘4-(4-methylpiperaziomethyl)-benzoylamido!-2-methylphenyl!-4-(3-pyridyl)2-pyridine-amine for the treatment of pulmonary hypertension

Publications (3)

Publication Number Publication Date
JP2006505582A JP2006505582A (ja) 2006-02-16
JP2006505582A5 true JP2006505582A5 (https=) 2006-12-07
JP4942297B2 JP4942297B2 (ja) 2012-05-30

Family

ID=32176700

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004546290A Expired - Fee Related JP4942297B2 (ja) 2002-10-25 2003-10-20 肺高血圧症の処置を目的としたｎ−｛５−［４−（４−メチルピペラジノメチル）−ベンゾイルアミド］−２−メチルフェニル｝−４−（３−ピリジル）−２−ピリジン−アミンの使用

Country Status (4)

Country Link
US (3) US20060154936A1 (https=)
JP (1) JP4942297B2 (https=)
AU (1) AU2003272007A1 (https=)
WO (1) WO2004037261A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1392313E (pt) * 2001-05-16 2007-07-17 Novartis Ag Combinação que compreende n - ( 5- [ 4- ( metil-piperazinomrtil ) - benxoilamido ] - 2 -metilfenil ) - 4 -( 3 - piridil ) - 2 - pirimidina-amina e um agente quimioterapêutico
AU2003244922A1 (en) * 2002-06-28 2004-01-19 The Administrators Of The Tulane Educational Fund 4-(4-methylpiperazin-1-ylmethyl)-n-(4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-benzamide for treating pulmonary fibrosis
ES2373912T3 (es) * 2005-01-28 2012-02-10 Novartis Ag Uso de pirimidilaminobenzamidas para el tratamiento de enfermedades que responden a la modulación de la actividad de quinasa tie-2.
EP1741432A1 (de) * 2005-07-07 2007-01-10 Universitätsklinikum Freiburg Tyrosinkinase-Inhibitor Imatinib zur Behandlung von Bluthochdruck
RU2431484C2 (ru) * 2005-11-10 2011-10-20 Байер Шеринг Фарма Акциенгезельшафт Диарилмочевина для лечения легочной гипертензии
CN101784269A (zh) * 2007-06-26 2010-07-21 莱西肯医药有限公司 治疗由5-羟色胺介导的疾病和病症的方法
CN101815534A (zh) * 2007-07-11 2010-08-25 莱西肯医药有限公司 用于治疗肺动脉高压以及相关疾病和病症的方法和组合物
BRPI0917491A2 (pt) * 2008-08-13 2015-12-01 Novartis Ag tratamento de hipertensao arterial pulmonar
EP3007689B1 (en) 2013-01-10 2018-03-07 Pulmokine, Inc. Non-selective kinase inhibitors
US9925184B2 (en) 2013-10-11 2018-03-27 Pulmokine, Inc. Spray-dry formulations
RU2763525C2 (ru) 2016-10-27 2021-12-30 Пульмокин, Инк. Комбинированная терапия для лечения легочной гипертензии
KR20190005708A (ko) * 2017-07-05 2019-01-16 이화여자대학교 산학협력단 에피디티오디옥소피페라진 화합물 또는 이의 유도체, 또는 이들의 약학적으로 허용가능한 염을 포함하는 폐동맥고혈압 예방 또는 치료용 약학적 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO4940418A1 (es) * 1997-07-18 2000-07-24 Novartis Ag Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
AU2002220720B2 (en) * 2000-11-28 2006-09-14 Mondobiotech Ag Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension
AU2003233946A1 (en) * 2002-03-15 2003-09-29 Novartis Ag 4-(4-methylpiperazin-1-ylmethyl)-n-(4-methyl-3(4-pyridin-3-yl)pyrimidin-2-yl-amino)phenyl)-benzamide for treating ang ii-mediated diseases

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