JP2006505582A5 - - Google Patents
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- Publication number
- JP2006505582A5 JP2006505582A5 JP2004546290A JP2004546290A JP2006505582A5 JP 2006505582 A5 JP2006505582 A5 JP 2006505582A5 JP 2004546290 A JP2004546290 A JP 2004546290A JP 2004546290 A JP2004546290 A JP 2004546290A JP 2006505582 A5 JP2006505582 A5 JP 2006505582A5
- Authority
- JP
- Japan
- Prior art keywords
- pulmonary hypertension
- combination
- prostacyclin
- inhalation
- day
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42131802P | 2002-10-25 | 2002-10-25 | |
| US60/421,318 | 2002-10-25 | ||
| PCT/IB2003/004671 WO2004037261A1 (en) | 2002-10-25 | 2003-10-20 | Use of n-‘5-‘4-(4-methylpiperaziomethyl)-benzoylamido!-2-methylphenyl!-4-(3-pyridyl)2-pyridine-amine for the treatment of pulmonary hypertension |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006505582A JP2006505582A (ja) | 2006-02-16 |
| JP2006505582A5 true JP2006505582A5 (https=) | 2006-12-07 |
| JP4942297B2 JP4942297B2 (ja) | 2012-05-30 |
Family
ID=32176700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004546290A Expired - Fee Related JP4942297B2 (ja) | 2002-10-25 | 2003-10-20 | 肺高血圧症の処置を目的としたｎ−｛５−［４−（４−メチルピペラジノメチル）−ベンゾイルアミド］−２−メチルフェニル｝−４−（３−ピリジル）−２−ピリジン−アミンの使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US20060154936A1 (https=) |
| JP (1) | JP4942297B2 (https=) |
| AU (1) | AU2003272007A1 (https=) |
| WO (1) | WO2004037261A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2444867C (en) * | 2001-05-16 | 2010-08-17 | Novartis Ag | Combination comprising n-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent |
| JP2005531628A (ja) * | 2002-06-28 | 2005-10-20 | ジ アドミニストレイターズ オブ ザ チューレン エデュケイショナル ファンド | 肺線維症の処置のための４−（４−メチルピペラジン−１−イルメチル）−ｎ−［４−メチル−３−（４−ピリジン−３−イル）ピリミジン−２−イルアミノ）フェニル］−ベンズアミド |
| ATE525073T1 (de) * | 2005-01-28 | 2011-10-15 | Novartis Ag | Verwendung von pyrimidylaminobenzamiden zur behandlung von durch modulation einer tie-2 kinase-aktivität verursachten krankheiten |
| EP1741432A1 (de) * | 2005-07-07 | 2007-01-10 | Universitätsklinikum Freiburg | Tyrosinkinase-Inhibitor Imatinib zur Behandlung von Bluthochdruck |
| RU2431484C2 (ru) * | 2005-11-10 | 2011-10-20 | Байер Шеринг Фарма Акциенгезельшафт | Диарилмочевина для лечения легочной гипертензии |
| EP2170306A1 (en) * | 2007-06-26 | 2010-04-07 | Lexicon Pharmaceuticals, Inc. | Methods of treating serotonin-mediated diseases and disorders |
| US7875622B2 (en) | 2007-07-11 | 2011-01-25 | Lexicon Pharmaceuticals, Inc. | Methods and compositions for treating pulmonary hypertension and related diseases and disorders |
| KR20110053354A (ko) * | 2008-08-13 | 2011-05-20 | 노파르티스 아게 | 폐동맥 고혈압의 치료 |
| ES2675720T3 (es) | 2013-01-10 | 2018-07-12 | Pulmokine, Inc. | Inhibidores de quinasa no selectivos |
| US9925184B2 (en) | 2013-10-11 | 2018-03-27 | Pulmokine, Inc. | Spray-dry formulations |
| CA3041679A1 (en) | 2016-10-27 | 2018-05-03 | Lawrence S. ZISMAN | Combination therapy for treating pulmonary hypertension |
| KR20190005708A (ko) * | 2017-07-05 | 2019-01-16 | 이화여자대학교 산학협력단 | 에피디티오디옥소피페라진 화합물 또는 이의 유도체, 또는 이들의 약학적으로 허용가능한 염을 포함하는 폐동맥고혈압 예방 또는 치료용 약학적 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CO4940418A1 (es) * | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| AU2072002A (en) * | 2000-11-28 | 2002-06-11 | Mondobiotech Sa | Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension |
| US20050124624A1 (en) * | 2002-03-15 | 2005-06-09 | Gilbert Richard E. | 4-(4-methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-yl-amino)phenyl]-benzamide for threating ang ii-mediated diseases |
-
2003
- 2003-10-20 US US10/532,297 patent/US20060154936A1/en not_active Abandoned
- 2003-10-20 WO PCT/IB2003/004671 patent/WO2004037261A1/en not_active Ceased
- 2003-10-20 JP JP2004546290A patent/JP4942297B2/ja not_active Expired - Fee Related
- 2003-10-20 AU AU2003272007A patent/AU2003272007A1/en not_active Abandoned
-
2010
- 2010-11-03 US US12/938,846 patent/US20110046150A1/en not_active Abandoned
-
2012
- 2012-04-30 US US13/459,896 patent/US20120214819A1/en not_active Abandoned
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