JP2006504645A5 - - Google Patents
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- Publication number
- JP2006504645A5 JP2006504645A5 JP2004519701A JP2004519701A JP2006504645A5 JP 2006504645 A5 JP2006504645 A5 JP 2006504645A5 JP 2004519701 A JP2004519701 A JP 2004519701A JP 2004519701 A JP2004519701 A JP 2004519701A JP 2006504645 A5 JP2006504645 A5 JP 2006504645A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- hcv
- antibody
- protein
- vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 30
- 108700008783 Hepatitis C virus E1 Proteins 0.000 claims 22
- 229960005486 vaccine Drugs 0.000 claims 17
- 239000003795 chemical substances by application Substances 0.000 claims 15
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 108090000623 proteins and genes Proteins 0.000 claims 13
- 102000004169 proteins and genes Human genes 0.000 claims 13
- 210000004027 cell Anatomy 0.000 claims 12
- 102000007079 Peptide Fragments Human genes 0.000 claims 10
- 108010033276 Peptide Fragments Proteins 0.000 claims 10
- 150000001413 amino acids Chemical class 0.000 claims 10
- 238000000034 method Methods 0.000 claims 6
- 101710185720 Putative ethidium bromide resistance protein Proteins 0.000 claims 5
- 101710125507 Integrase/recombinase Proteins 0.000 claims 3
- 210000001124 body fluid Anatomy 0.000 claims 3
- 239000010839 body fluid Substances 0.000 claims 3
- 241000701044 Human gammaherpesvirus 4 Species 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 241000711549 Hepacivirus C Species 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 210000004408 hybridoma Anatomy 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 150000003384 small molecules Chemical group 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/188,608 US20030180284A1 (en) | 1998-11-05 | 2002-07-02 | Prevention and treatment of HCV infection employing antibodies directed against conformational and linear epitopes |
| PCT/US2003/020580 WO2004005316A2 (en) | 2002-07-02 | 2003-06-27 | Prevention and treatment of hcv infection employing antibodies directed against conformational and linear epitopes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006504645A JP2006504645A (ja) | 2006-02-09 |
| JP2006504645A5 true JP2006504645A5 (enExample) | 2006-08-17 |
Family
ID=30114012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004519701A Pending JP2006504645A (ja) | 2002-07-02 | 2003-06-27 | 立体構造及び直鎖状エピトープに対する抗体を用いたｈｃｖ感染の予防及び治療 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20030180284A1 (enExample) |
| EP (1) | EP1572721A4 (enExample) |
| JP (1) | JP2006504645A (enExample) |
| AU (1) | AU2003247841A1 (enExample) |
| WO (1) | WO2004005316A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060188511A1 (en) * | 1998-11-05 | 2006-08-24 | Foung Steven K | Prevention and treatment of HCV infection employing antibodies directed against conformational and linear epitopes |
| US7250166B2 (en) * | 2001-01-12 | 2007-07-31 | Molecules Of Man Ab | Human monoclonal antibodies that bind hepatitis C virus (HCV) E1 |
| FR2843115B1 (fr) * | 2002-08-02 | 2007-11-09 | Commissariat Energie Atomique | Melange de peptides issus des proteines c et ns3 du virus de l'hepatite c et leurs applications |
| WO2006097682A1 (en) * | 2005-03-18 | 2006-09-21 | Ucl Business Plc | Mechano growth factor peptides and their use |
| US20090311248A1 (en) * | 2006-03-22 | 2009-12-17 | Erik Depla | Hepatitis C Virus Neutralizing Antibodies |
| WO2008108918A1 (en) * | 2007-02-21 | 2008-09-12 | University Of Massachusetts | Human antibodies against hepatitis c virus (hcv) uses thereof |
| CN101809033A (zh) | 2007-07-25 | 2010-08-18 | 日本国立感染症研究所 | 对丙型肝炎病毒(hcv)感染具有抑制活性的抗体和其用途 |
| WO2010047829A1 (en) * | 2008-10-24 | 2010-04-29 | The Scripps Research Institute | Mutant hepatitis c virus e2 polypeptides for hcv treatment |
| US8592559B2 (en) | 2009-10-30 | 2013-11-26 | Toray Industries, Inc. | Antibody having activity of inhibiting hepatitis C virus (HCV) infection and use thereof |
| EP3121273A4 (en) * | 2014-03-20 | 2017-08-30 | Japan As Represented By Director-General Of National Institute Of Infectious Diseases | Antibody having infection-inhibiting activity against hepatitis c virus |
| CN106749645B (zh) * | 2016-11-14 | 2019-12-03 | 广州泰诺迪生物科技有限公司 | 一种全人源抗丙型肝炎病毒的中和抗体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69233104T2 (de) * | 1991-07-15 | 2004-05-13 | The Wellcome Foundation Ltd., Greenford | Herstellung von Antikörpern |
| EP0608261B1 (en) * | 1991-09-13 | 2002-11-27 | Chiron Corporation | Immunoreactive hepatitis c virus polypeptide compositions |
| JPH09503396A (ja) * | 1994-07-29 | 1997-04-08 | インノジェネティクス・エヌ・ブイ | 診断用及び治療用の精製ｃ型肝炎ウイルスエンベロープ蛋白 |
| IL118626A0 (en) * | 1996-06-11 | 1996-10-16 | Xtl Biopharmaceuticals Limited | Anti HBV antibody |
| EP0947525A1 (en) * | 1998-03-27 | 1999-10-06 | Innogenetics N.V. | Epitopes in viral envelope proteins and specific antibodies directed against these epitopes: use for detection of HCV viral antigen in host tissue |
| US6682909B2 (en) * | 2000-09-13 | 2004-01-27 | Hawaii Biotech, Inc. | Immunogenic composition of hepatitis C and methods of use thereof |
-
2002
- 2002-07-02 US US10/188,608 patent/US20030180284A1/en not_active Abandoned
-
2003
- 2003-06-27 EP EP03763059A patent/EP1572721A4/en not_active Withdrawn
- 2003-06-27 AU AU2003247841A patent/AU2003247841A1/en not_active Abandoned
- 2003-06-27 WO PCT/US2003/020580 patent/WO2004005316A2/en not_active Ceased
- 2003-06-27 JP JP2004519701A patent/JP2006504645A/ja active Pending
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