JP2006503914A5 - - Google Patents

Download PDF

Info

Publication number
JP2006503914A5
JP2006503914A5 JP2005501623A JP2005501623A JP2006503914A5 JP 2006503914 A5 JP2006503914 A5 JP 2006503914A5 JP 2005501623 A JP2005501623 A JP 2005501623A JP 2005501623 A JP2005501623 A JP 2005501623A JP 2006503914 A5 JP2006503914 A5 JP 2006503914A5
Authority
JP
Japan
Prior art keywords
hpv
protein
polypeptide
individual
epitope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2005501623A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006503914A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/032705 external-priority patent/WO2004037175A2/en
Publication of JP2006503914A publication Critical patent/JP2006503914A/ja
Publication of JP2006503914A5 publication Critical patent/JP2006503914A5/ja
Pending legal-status Critical Current

Links

JP2005501623A 2002-10-21 2003-10-16 ヒトパピローマウイルス媒介性疾患を治療するための組成物および方法 Pending JP2006503914A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42006802P 2002-10-21 2002-10-21
US47148103P 2003-05-15 2003-05-15
PCT/US2003/032705 WO2004037175A2 (en) 2002-10-21 2003-10-16 Compositions and methods for treating human papillomavirus-mediated disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010275323A Division JP2011121946A (ja) 2002-10-21 2010-12-10 ヒトパピローマウイルス媒介性疾患を治療するための組成物および方法

Publications (2)

Publication Number Publication Date
JP2006503914A JP2006503914A (ja) 2006-02-02
JP2006503914A5 true JP2006503914A5 (enExample) 2006-08-17

Family

ID=32179780

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2005501623A Pending JP2006503914A (ja) 2002-10-21 2003-10-16 ヒトパピローマウイルス媒介性疾患を治療するための組成物および方法
JP2010275323A Pending JP2011121946A (ja) 2002-10-21 2010-12-10 ヒトパピローマウイルス媒介性疾患を治療するための組成物および方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010275323A Pending JP2011121946A (ja) 2002-10-21 2010-12-10 ヒトパピローマウイルス媒介性疾患を治療するための組成物および方法

Country Status (8)

Country Link
US (2) US20060247190A1 (enExample)
EP (1) EP1556513B1 (enExample)
JP (2) JP2006503914A (enExample)
AT (1) ATE465753T1 (enExample)
AU (2) AU2003284239B2 (enExample)
CA (1) CA2502696A1 (enExample)
DE (1) DE60332377D1 (enExample)
WO (1) WO2004037175A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2443216T3 (es) * 2006-04-19 2014-02-18 Postech Academy-Industry Foundation Proteínas de fusión que comprenden polipéptidos de VPH y péptidos de inmunopotenciación de tratamiento y prevención del cáncer cervicouterino
EP2013230A2 (en) * 2006-04-21 2009-01-14 Transgene S.A. Hpv-16-based papillomavirus vaccine
AU2007241405A1 (en) * 2006-04-21 2007-11-01 Transgene S.A. HPV-18-based papillomavirus vaccine
CN105063064B (zh) * 2006-07-28 2024-09-24 宾夕法尼亚大学托管会 改进的疫苗及其使用方法
US8877206B2 (en) 2007-03-22 2014-11-04 Pds Biotechnology Corporation Stimulation of an immune response by cationic lipids
AU2009236306B2 (en) 2008-04-17 2015-04-02 Pds Biotechnology Corporation Stimulation of an immune response by enantiomers of cationic lipids
CA2731444A1 (en) * 2008-09-02 2010-03-11 Antigen Express, Inc. Human papillomavirus / li-key hybrids and methods of use
EP2601968A1 (en) 2011-12-06 2013-06-12 Deutsches Krebsforschungszentrum HPV derived polynucleic acids for therapy
AU2013274235B2 (en) 2012-06-15 2018-01-18 Samir N. Khleif Cationic lipid vaccine compositions and methods of use
AU2013317805B2 (en) 2012-09-21 2018-07-26 Pds Biotechnology Corporation Improved vaccine compositions and methods of use
US11612652B2 (en) 2015-11-13 2023-03-28 Pds Biotechnology Corporation Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy
EP3518966A1 (en) * 2016-09-29 2019-08-07 GlaxoSmithKline Biologicals S.A. Compositions and methods of treatment of persistent hpv infection
MX2019011324A (es) 2017-03-23 2020-01-21 Massachusetts Gen Hospital Bloqueo de cxcr4/cxcr7 y tratamiento de enfermedad asociada con el virus del papiloma humano.
CN118370809A (zh) * 2017-04-03 2024-07-23 百欧恩泰美国公司 蛋白质抗原及其用途
CN111655238A (zh) 2017-12-05 2020-09-11 Pds生物科技公司 用于刺激i型干扰素基因的包括阳离子脂质的方法和组合物
SG11202105276TA (en) 2018-12-03 2021-06-29 Univ Texas Oligo-benzamide analogs and their use in cancer treatment
US20220334132A1 (en) * 2019-08-08 2022-10-20 The Trustees Of Indiana University Methods for identifying and treating urinary tract infections
CN112957461B (zh) * 2021-02-02 2023-01-10 南开大学 一种形貌可控自佐剂宫颈癌多肽疫苗的制备及性能表征方法
JP2023062338A (ja) * 2021-10-21 2023-05-08 国立大学法人神戸大学 がんワクチン
WO2024180232A1 (en) * 2023-03-02 2024-09-06 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Therapeutic hpv vaccines based on validated target epitopes

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987005630A1 (en) * 1986-03-21 1987-09-24 Institut Pasteur Determined dna sequences derived from a papillomavirus genome, their uses for in vitro diagnostic purposes and the production of antigenic compositions
US4741872A (en) * 1986-05-16 1988-05-03 The University Of Kentucky Research Foundation Preparation of biodegradable microspheres useful as carriers for macromolecules
US4777239A (en) * 1986-07-10 1988-10-11 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic peptides of human papilloma virus
US6007806A (en) * 1986-08-13 1999-12-28 Transgene S.A. Expression of a tumor-specific antigen by a recombinant vector virus and use thereof in preventive or curative treatment of the corresponding tumor
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
DE3907721A1 (de) * 1989-03-10 1990-09-20 Behringwerke Ag Immunogene regionen auf dem e7-protein des humanen papillomvierus typ 16
US5703055A (en) * 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5753233A (en) * 1990-05-10 1998-05-19 Behring Diagnostics Gmbh Seroreactive epitopes on proteins of human papilloma-virus (HPV) 18
US5932412A (en) * 1990-05-11 1999-08-03 Euro-Diagnostica Ab Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US6183745B1 (en) * 1990-12-12 2001-02-06 The University Of Queensland Subunit papilloma virus vaccine and peptides for use therein
SE9003978D0 (sv) 1990-12-13 1990-12-13 Henrik Garoff Dna expressionssystem baserade paa ett virus replikon
GB9105383D0 (en) * 1991-03-14 1991-05-01 Immunology Ltd An immunotherapeutic for cervical cancer
US5543294A (en) 1991-07-19 1996-08-06 The Trustees Of Columbia University In The City Of New York Polymerase chain reaction/restriction fragment length polymorphism method for the detection and typing of myobacteria
US5709860A (en) * 1991-07-25 1998-01-20 Idec Pharmaceuticals Corporation Induction of cytotoxic T-lymphocyte responses
US6037135A (en) 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
US5656297A (en) * 1992-03-12 1997-08-12 Alkermes Controlled Therapeutics, Incorporated Modulated release from biocompatible polymers
WO1993017668A1 (en) * 1992-03-12 1993-09-16 Alkermes Controlled Therapeutics, Inc. Controlled release acth containing microspheres
DE69332485T2 (de) * 1992-08-11 2003-11-13 The President And Fellows Of Harvard College, Cambridge Immunmodulierende peptide
US5462520A (en) 1992-08-17 1995-10-31 Genetronics, Inc. Transsurface drug delivery by electrofusion of microbubbles to the tissue surface
US5633234A (en) * 1993-01-22 1997-05-27 The Johns Hopkins University Lysosomal targeting of immunogens
US5593972A (en) * 1993-01-26 1997-01-14 The Wistar Institute Genetic immunization
ATE386800T1 (de) * 1993-03-17 2008-03-15 Us Gov Health & Human Serv Immunogene chimäre umfassend nucleinsäuresequenzen, die signalsequenzpeptide des endoplasmatischen reticulums und mindestens ein anderes peptid codieren, deren verwendung in impfstoffen und zur behandlung von krankheiten
US5993434A (en) 1993-04-01 1999-11-30 Genetronics, Inc. Method of treatment using electroporation mediated delivery of drugs and genes
US5679647A (en) * 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US5679509A (en) * 1993-09-28 1997-10-21 University Of New Mexico Methods and a diagnostic aid for distinguishing a subset of HPV that is associated with an increased risk of developing cervical dysplasia and cervical cancer
US5643605A (en) * 1993-10-25 1997-07-01 Genentech, Inc. Methods and compositions for microencapsulation of adjuvants
EP0804249A2 (en) 1994-03-15 1997-11-05 Brown University Research Foundation Polymeric gene delivery system
US6239116B1 (en) 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US5736524A (en) * 1994-11-14 1998-04-07 Merck & Co.,. Inc. Polynucleotide tuberculosis vaccine
AUPN015794A0 (en) * 1994-12-20 1995-01-19 Csl Limited Variants of human papilloma virus antigens
AU5297496A (en) 1995-02-17 1996-09-04 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Methods of preparation and use of recombinant adenoviral vectors
US5840306A (en) * 1995-03-22 1998-11-24 Merck & Co., Inc. DNA encoding human papillomavirus type 18
US5962428A (en) * 1995-03-30 1999-10-05 Apollon, Inc. Compositions and methods for delivery of genetic material
US5705151A (en) * 1995-05-18 1998-01-06 National Jewish Center For Immunology & Respiratory Medicine Gene therapy for T cell regulation
AUPN443995A0 (en) * 1995-07-27 1995-08-17 Csl Limited Papillomavirus polyprotein
US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
US5626161A (en) * 1996-04-29 1997-05-06 Fu Tai Umbrella Works, Ltd. Multiple-fold automatic umbrella with simplified reliable control means
KR100620481B1 (ko) * 1996-10-23 2006-09-06 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 개선된 백신
US20020103145A1 (en) * 1999-05-19 2002-08-01 Adrian Bot Immunization of infants
AU5608798A (en) * 1996-12-20 1998-07-17 Merck & Co., Inc. Formulations of recombinant papillomavirus vaccines
US5783567A (en) * 1997-01-22 1998-07-21 Pangaea Pharmaceuticals, Inc. Microparticles for delivery of nucleic acid
US6261281B1 (en) 1997-04-03 2001-07-17 Electrofect As Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
US6183746B1 (en) * 1997-10-09 2001-02-06 Zycos Inc. Immunogenic peptides from the HPV E7 protein
US6013258A (en) * 1997-10-09 2000-01-11 Zycos Inc. Immunogenic peptides from the HPV E7 protein
GB9722766D0 (en) 1997-10-28 1997-12-24 British Telecomm Portable computers
PT1038022E (pt) 1997-12-12 2005-11-30 Digene Corp Avaliacao de doencas relacionadas com o virus papiloma humano
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
CA2685270C (en) * 1998-05-13 2014-07-29 Pharmexa Inc. Expression vectors for stimulating an immune response and methods of using the same
US6406719B1 (en) 1998-05-13 2002-06-18 Microbiological Research Authority Encapsulation of bioactive agents
DE69933679T2 (de) 1998-08-12 2007-08-23 Zycos Inc., Cambridge Darstellung des profils und katalogisierung von exprimierten proteinmarkern
EP1108035B1 (en) * 1998-09-04 2007-08-08 Sanofi Pasteur Limited Treatment of cervical cancer
CA2276066A1 (en) 1999-03-11 2000-09-11 Zycos Inc. Microparticles for delivery of nucleic acid
EP1214097B3 (en) * 1999-09-16 2011-07-20 Eisai Inc. Nucleic acids encoding polyepitope polypeptides
US20050100928A1 (en) * 1999-09-16 2005-05-12 Zycos Inc., A Delaware Corporation Nucleic acids encoding polyepitope polypeptides
WO2001027291A1 (en) * 1999-10-12 2001-04-19 Institut Pasteur Design of a polyepitopic construct for the induction of hla-a2.1 restricted hiv 1 specific ctl responses using hhd mice
EP1230338B1 (en) 1999-11-19 2006-03-08 Zycos Inc. Continuous-flow method for preparing microparticles
WO2001097795A2 (en) 2000-06-22 2001-12-27 3M Innovative Properties Company Systems and methods for treating a mucosal surface
HRP20021015A2 (en) * 2000-06-26 2004-02-29 Stressgen Biotechnologies Corp Human papilloma virus treatment
GB0017990D0 (en) * 2000-07-21 2000-09-13 Glaxo Group Ltd Papilloma virus sequences

Similar Documents

Publication Publication Date Title
JP2011121946A (ja) ヒトパピローマウイルス媒介性疾患を治療するための組成物および方法
JP2006503914A5 (enExample)
Yan et al. Induction of antitumor immunity in vivo following delivery of a novel HPV-16 DNA vaccine encoding an E6/E7 fusion antigen
EP1296711B1 (en) Hpv-e7 for human papilloma virus treatment
EP2167137B1 (en) Hpv polyepitope constructs and uses thereof
EP1108035B1 (en) Treatment of cervical cancer
CA2305683C (en) Immunogenic peptides from the hpv e7 protein
JP2004535816A (ja) Cinを含むhpv関連の前癌性増殖および癌性増殖に関する方法および組成物
Cheung et al. Plasmid encoding papillomavirus Type 16 (HPV16) DNA constructed with codon optimization improved the immunogenicity against HPV infection
TW200840869A (en) Papillomavirus vaccine
TW201941786A (zh) 一種新型多價hpv 疫苗成份
CN103476424A (zh) Cyaa携带的多肽及其在诱导治疗性和预防性免疫应答中的应用
JP2023525558A (ja) 再発性呼吸器乳頭腫症のためのワクチン及びそれを使用する方法
Ayesha et al. Physiopathology and effectiveness of therapeutic vaccines against human papillomavirus
CN114409744B (zh) Hpv抗原表位及其鉴定方法、应用
JP2013143953A (ja) Hml−2ポリペプチド発現用ベクター
CN116217675B (zh) Hpv抗原表位及其应用
CN100393878C (zh) 疫苗
EP1390074B1 (en) Novel compositions and uses therefor
JP2002532434A (ja) パピローマウイルス感染の治療方法
CN114478712B (zh) Hpv抗原表位及其鉴定方法、应用
WO2007033533A1 (en) Use of nocardia rubra cell wall skeleton to produce medicaments for resisting human papilloma virus hpv
AU2019276162B2 (en) Combined prophylactic and therapeutic vaccines
AU2023358768A1 (en) Vaccines for recurrent respiratory papillomatosis and methods of using the same
CN115569189A (zh) 治疗hpv感染的疫苗组合