JP2006501298A5 - - Google Patents
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- Publication number
- JP2006501298A5 JP2006501298A5 JP2004541124A JP2004541124A JP2006501298A5 JP 2006501298 A5 JP2006501298 A5 JP 2006501298A5 JP 2004541124 A JP2004541124 A JP 2004541124A JP 2004541124 A JP2004541124 A JP 2004541124A JP 2006501298 A5 JP2006501298 A5 JP 2006501298A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- rejection
- pharmaceutical composition
- composition
- integer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 39
- 239000008194 pharmaceutical composition Substances 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 14
- 206010052779 Transplant rejections Diseases 0.000 claims 12
- 208000023275 Autoimmune disease Diseases 0.000 claims 8
- 208000026935 allergic disease Diseases 0.000 claims 8
- 210000000056 organ Anatomy 0.000 claims 8
- 210000001519 tissue Anatomy 0.000 claims 8
- 208000032116 Autoimmune Experimental Encephalomyelitis Diseases 0.000 claims 4
- 208000011231 Crohn disease Diseases 0.000 claims 4
- 208000030836 Hashimoto thyroiditis Diseases 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 4
- 201000004681 Psoriasis Diseases 0.000 claims 4
- 206010039085 Rhinitis allergic Diseases 0.000 claims 4
- 206010058141 Skin graft rejection Diseases 0.000 claims 4
- 239000002671 adjuvant Substances 0.000 claims 4
- 201000010105 allergic rhinitis Diseases 0.000 claims 4
- 208000006673 asthma Diseases 0.000 claims 4
- 210000001185 bone marrow Anatomy 0.000 claims 4
- 208000017760 chronic graft versus host disease Diseases 0.000 claims 4
- 206010012601 diabetes mellitus Diseases 0.000 claims 4
- 208000012997 experimental autoimmune encephalomyelitis Diseases 0.000 claims 4
- 208000030603 inherited susceptibility to asthma Diseases 0.000 claims 4
- 201000006417 multiple sclerosis Diseases 0.000 claims 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims 4
- 230000002265 prevention Effects 0.000 claims 4
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 4
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 4
- 229920001515 polyalkylene glycol Polymers 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 230000000747 cardiac effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000007911 parenteral administration Methods 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 239000003826 tablet Substances 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 0 CC1(*)C=NC(C)=C1 Chemical compound CC1(*)C=NC(C)=C1 0.000 description 1
- ZFRKQXVRDFCRJG-UHFFFAOYSA-N Cc1c[nH]c2ccccc12 Chemical compound Cc1c[nH]c2ccccc12 ZFRKQXVRDFCRJG-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41550802P | 2002-10-03 | 2002-10-03 | |
| PCT/IB2003/004993 WO2004031129A2 (en) | 2002-10-03 | 2003-10-01 | Compounds for use in the treatment of autoimmune diseases, immuno-allergical diseases and organ or tissue transplantation rejection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006501298A JP2006501298A (ja) | 2006-01-12 |
| JP2006501298A5 true JP2006501298A5 (https=) | 2006-11-30 |
| JP4667870B2 JP4667870B2 (ja) | 2011-04-13 |
Family
ID=32069867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004541124A Expired - Fee Related JP4667870B2 (ja) | 2002-10-03 | 2003-10-01 | 自己免疫疾患、免疫−アレルギー疾患及び臓器又は組織移植拒絶反応の治療において使用する新規な化合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7642290B2 (https=) |
| EP (1) | EP1546088B1 (https=) |
| JP (1) | JP4667870B2 (https=) |
| AU (2) | AU2003274605A1 (https=) |
| CA (1) | CA2500935C (https=) |
| CY (1) | CY1116107T1 (https=) |
| DK (1) | DK1546088T3 (https=) |
| ES (1) | ES2535975T3 (https=) |
| IL (1) | IL167631A (https=) |
| PT (1) | PT1546088E (https=) |
| SI (1) | SI1546088T1 (https=) |
| WO (1) | WO2004031129A2 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1546088B1 (en) | 2002-10-03 | 2014-12-17 | Novaremed Ltd. | Compounds for use in the treatment of autoimmune diseases, immuno-allergical diseases and organ or tissue transplantation rejection |
| JP4939396B2 (ja) * | 2004-03-26 | 2012-05-23 | ノヴァレメッド リミテッド | Ａｉｄｓ及び他のウイルス性疾患及びｈｉｖ関連感染症の改善又はその治療用化合物及びそのような化合物を含む組成物、そのような疾患及び感染症の治療方法及びそのような化合物及び組成物の製造方法 |
| RU2309144C2 (ru) * | 2005-03-25 | 2007-10-27 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Фенилсодержащие n-ацильные производные аминов, способ их получения, фармацевтическая композиция и их применение в качестве противовоспалительных и анальгетических средств |
| FR2892923B1 (fr) * | 2005-11-08 | 2009-01-16 | Engelhard Lyon Sa | Utilisatiion des derives de l'acide para-coumarique ou para- hydroxycinnamique dans des compositions cosmetiques ou dermatologiques. |
| EP2026775B1 (en) * | 2006-05-09 | 2015-04-29 | Novaremed Ltd. | Use of syk tyrosine kinase inhibitors for the treatment of cell proliferative disorders |
| CA2669104A1 (en) * | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity |
| EP2003118A1 (de) * | 2007-06-13 | 2008-12-17 | Bayer Schering Pharma Aktiengesellschaft | Zimtsäurederivate als Modulatoren des EP2-Rezeptors |
| EP2014287A1 (de) * | 2007-06-13 | 2009-01-14 | Bayer Schering Pharma Aktiengesellschaft | Verwendung von Zimtsäurederivaten als Modulatoren des EP2-Rezeptors |
| US20090017004A1 (en) * | 2007-07-11 | 2009-01-15 | Enzon Pharmaceuticals, Inc. | Polymeric drug delivery systems containing an aromatic allylic acid |
| GB0804213D0 (en) | 2008-03-06 | 2008-04-16 | New Era Biotech Ltd | A method of printing or preventing pain |
| EP2475361B1 (en) * | 2009-09-09 | 2019-11-06 | Novaremed Ltd. | N-substituted benzenepropanamides for use in the treatment of pain and inflammation |
| US8802734B2 (en) * | 2009-09-09 | 2014-08-12 | Novaremed Limited | Method of treating or preventing pain |
| GB201116335D0 (en) * | 2011-09-21 | 2011-11-02 | Novaremed Ltd | A method of treating or preventing affective disorders |
| DK2788317T3 (da) | 2011-12-08 | 2020-01-20 | Novaremed Ltd | Isolerede stereoisomere former af (S)2-N(3-O-((S)propan-2-ol)-1-propyl-4-hydroxybenzen)-3-phenylpropylamid |
| WO2015173813A1 (en) * | 2014-05-14 | 2015-11-19 | Novaremed Ltd. | Pharmaceutical composition comprising stereoisomers of n-(1-(4-hydroxyphenyl)-3-(2-hydroxypropoxy)propan-2-yl)-3-phenylpropanamide for the prevention and treatment of type ii diabetes |
| ES2578377B1 (es) | 2014-12-22 | 2017-05-04 | Consejo Superior De Investigaciones Científicas (Csic) | Compuestos moduladores del sensor neuronal de calcio dream y sus usos terapéuticos. |
| WO2018053116A1 (en) | 2016-09-14 | 2018-03-22 | Invisalert Solutions, LLC | Tamper resistant clasp and wristband apparatus and associated patient monitoring system and method of use |
| CA3087269A1 (en) | 2018-01-10 | 2019-07-18 | Brightseed, Inc. | Method for modulating metabolism |
| US12017973B2 (en) | 2018-06-22 | 2024-06-25 | Basf Se | Amino acid based surfactants as formulants for biocides |
| USD906359S1 (en) | 2018-07-05 | 2020-12-29 | Invisalert Solutions, Inc. | Display screen with graphical user interface |
| CN113329746B (zh) | 2019-01-23 | 2025-05-02 | 诺瓦麦有限公司 | 用于治疗或预防疼痛、炎症和/或自身免疫的化合物 |
| CN114929033A (zh) * | 2019-07-29 | 2022-08-19 | 布莱特西德公司 | 改善消化健康的方法 |
| CA3153945A1 (en) | 2019-09-11 | 2021-03-18 | Invisalert Solutions, Inc. | Wireless patient monitoring compliance system |
| US12315353B1 (en) | 2024-06-04 | 2025-05-27 | Invisalert Solutions, Inc. | Patient safety monitoring method and apparatus |
| US12355745B1 (en) | 2024-10-28 | 2025-07-08 | Invisalert Solutions, Inc. | Secure mobile device management |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2908691A (en) | 1958-07-14 | 1959-10-13 | Searle & Co | Hydroxyphenalkylaminoalkylindoles and ethers corresponding thereto |
| ZA732136B (en) | 1972-04-12 | 1974-03-27 | Lilly Co Eli | Dopamine derivatives |
| JPS5236606A (en) * | 1975-09-12 | 1977-03-22 | Tanabe Seiyaku Co Ltd | Process for preparation of amino compounds |
| US4766106A (en) * | 1985-06-26 | 1988-08-23 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polymer conjugation |
| US4908322A (en) | 1985-09-06 | 1990-03-13 | The United States Of America As Represented By The Department Of Health And Human Services | Derivatization of amines for electrochemical detection |
| US5693622A (en) | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5552558A (en) | 1989-05-23 | 1996-09-03 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| WO1994003427A1 (en) | 1992-08-06 | 1994-02-17 | Warner-Lambert Company | 2-thioindoles (selenoindoles) and related disulfides (selenides) which inhibit protein tyrosine kinases and which have antitumor properties |
| IS2334B (is) | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
| JP2848232B2 (ja) * | 1993-02-19 | 1999-01-20 | 武田薬品工業株式会社 | アルデヒド誘導体 |
| US5566064A (en) | 1995-05-26 | 1996-10-15 | Apple Computer, Inc. | High efficiency supply for electroluminescent panels |
| AU1463997A (en) * | 1995-12-22 | 1997-07-17 | Acea Pharmaceuticals, Inc. | Subtype-selective nmda receptor ligands and the use thereof |
| EP0887340A4 (en) | 1996-02-06 | 2000-03-29 | Japan Tobacco Inc | CHEMICAL COMPOUNDS AND THEIR PHARMACEUTICAL USE |
| ID19116A (id) | 1996-10-15 | 1998-06-18 | Nippon Catalytic Chem Ind | Bahan pengabsorpsi air dan proses produksinya |
| US6110922A (en) * | 1998-12-29 | 2000-08-29 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds |
| WO2002046176A1 (en) | 2000-12-05 | 2002-06-13 | Nippon Chemiphar Co., Ltd. | Ppar (peroxisome proliferator activated receptor) activators |
| EP1546088B1 (en) | 2002-10-03 | 2014-12-17 | Novaremed Ltd. | Compounds for use in the treatment of autoimmune diseases, immuno-allergical diseases and organ or tissue transplantation rejection |
| JP4939396B2 (ja) * | 2004-03-26 | 2012-05-23 | ノヴァレメッド リミテッド | Ａｉｄｓ及び他のウイルス性疾患及びｈｉｖ関連感染症の改善又はその治療用化合物及びそのような化合物を含む組成物、そのような疾患及び感染症の治療方法及びそのような化合物及び組成物の製造方法 |
| RU2309144C2 (ru) | 2005-03-25 | 2007-10-27 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Фенилсодержащие n-ацильные производные аминов, способ их получения, фармацевтическая композиция и их применение в качестве противовоспалительных и анальгетических средств |
| EP2026775B1 (en) * | 2006-05-09 | 2015-04-29 | Novaremed Ltd. | Use of syk tyrosine kinase inhibitors for the treatment of cell proliferative disorders |
| AU2008302356A1 (en) | 2007-09-17 | 2009-03-26 | Academia Sinica | Compositions and methods for treating inflammation and inflammation-related disorders by Plectranthus Amboinicus extracts |
| CN101503373B (zh) | 2009-03-13 | 2013-07-24 | 山东大学 | 2-氨基-1-(4-硝基苯基)-1-乙醇类金属蛋白酶抑制剂及其制备方法和用途 |
-
2003
- 2003-10-01 EP EP03758581.7A patent/EP1546088B1/en not_active Expired - Lifetime
- 2003-10-01 AU AU2003274605A patent/AU2003274605A1/en not_active Abandoned
- 2003-10-01 CA CA2500935A patent/CA2500935C/en not_active Expired - Fee Related
- 2003-10-01 US US10/530,116 patent/US7642290B2/en not_active Expired - Fee Related
- 2003-10-01 SI SI200332415T patent/SI1546088T1/sl unknown
- 2003-10-01 WO PCT/IB2003/004993 patent/WO2004031129A2/en not_active Ceased
- 2003-10-01 DK DK03758581.7T patent/DK1546088T3/en active
- 2003-10-01 JP JP2004541124A patent/JP4667870B2/ja not_active Expired - Fee Related
- 2003-10-01 ES ES03758581.7T patent/ES2535975T3/es not_active Expired - Lifetime
- 2003-10-01 PT PT37585817T patent/PT1546088E/pt unknown
-
2005
- 2005-03-23 IL IL167631A patent/IL167631A/en active IP Right Grant
-
2009
- 2009-08-21 US US12/583,485 patent/US8309606B2/en not_active Expired - Fee Related
-
2010
- 2010-12-15 AU AU2010257331A patent/AU2010257331B2/en not_active Ceased
-
2015
- 2015-03-13 CY CY20151100252T patent/CY1116107T1/el unknown
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