JP2006501202A5 - - Google Patents

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Publication number
JP2006501202A5
JP2006501202A5 JP2004523753A JP2004523753A JP2006501202A5 JP 2006501202 A5 JP2006501202 A5 JP 2006501202A5 JP 2004523753 A JP2004523753 A JP 2004523753A JP 2004523753 A JP2004523753 A JP 2004523753A JP 2006501202 A5 JP2006501202 A5 JP 2006501202A5
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JP
Japan
Prior art keywords
alkyl
aryl
independently
group
alkylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004523753A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006501202A (ja
JP4568113B2 (ja
Filing date
Publication date
Priority claimed from DE10233817A external-priority patent/DE10233817A1/de
Application filed filed Critical
Publication of JP2006501202A publication Critical patent/JP2006501202A/ja
Publication of JP2006501202A5 publication Critical patent/JP2006501202A5/ja
Application granted granted Critical
Publication of JP4568113B2 publication Critical patent/JP4568113B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2004523753A 2002-07-25 2003-07-18 Ｍｃｈ調節作用を有するジアリール置換環状尿素誘導体 Expired - Fee Related JP4568113B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10233817A DE10233817A1 (de) 2002-07-25 2002-07-25 Substituierte Diarylheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PCT/EP2003/007891 WO2004011438A1 (de) 2002-07-25 2003-07-18 Diarylsubstituierte cyclische harnstoffderivate mit mch-modulatorischer wirkung

Publications (3)

Publication Number Publication Date
JP2006501202A JP2006501202A (ja) 2006-01-12
JP2006501202A5 true JP2006501202A5 (enExample) 2006-08-31
JP4568113B2 JP4568113B2 (ja) 2010-10-27

Family

ID=30128364

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004523753A Expired - Fee Related JP4568113B2 (ja) 2002-07-25 2003-07-18 Ｍｃｈ調節作用を有するジアリール置換環状尿素誘導体

Country Status (14)

Country Link
EP (1) EP1551810B1 (enExample)
JP (1) JP4568113B2 (enExample)
AR (1) AR040514A1 (enExample)
AT (1) ATE535513T1 (enExample)
AU (2) AU2003257465A1 (enExample)
BR (1) BR0312916A (enExample)
CA (1) CA2493924A1 (enExample)
DE (1) DE10233817A1 (enExample)
IL (1) IL166471A (enExample)
MX (1) MXPA05001048A (enExample)
MY (1) MY142551A (enExample)
PE (1) PE20040702A1 (enExample)
TW (1) TW200408627A (enExample)
WO (2) WO2004012648A2 (enExample)

Families Citing this family (39)

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DE102004003811A1 (de) * 2004-01-25 2005-08-11 Aventis Pharma Deutschland Gmbh Substituierte N-Cyclohexylimidazolinone, Verfahren ihrer Herstellung und ihre Verwendung als Arzneimittel
US7241787B2 (en) 2004-01-25 2007-07-10 Sanofi-Aventis Deutschland Gmbh Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments
US8372848B2 (en) * 2004-03-23 2013-02-12 Mixture Sciences, Inc. Melanin-concentrating hormone receptor antagonists and methods of use
WO2006015279A1 (en) * 2004-07-28 2006-02-09 Neurogen Corporation Heterocyclic diamine compounds as ligands of the melanin concentrating hormone receptor useful for the treatment of obesity, diabetes, eating and sexual disorders
EP1634598A1 (en) * 2004-09-07 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Use of piperazine derivatives and analogues for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion
WO2007063760A1 (ja) * 2005-11-30 2007-06-07 Mitsubishi Chemical Corporation 有機化合物、電荷輸送材料、電荷輸送材料用組成物および有機電界発光素子
JP5250967B2 (ja) * 2005-11-30 2013-07-31 三菱化学株式会社 有機化合物、電荷輸送材料、電荷輸送材料用組成物および有機電界発光素子
CN101341135B (zh) 2005-12-21 2013-08-14 詹森药业有限公司 治疗mch-1介导的疾病的取代的吡嗪酮衍生物
BRPI0707870A2 (pt) * 2006-02-15 2011-05-10 Sanofi Aventis ariltienopirimidinonas substituÍdas com amino Álcool, processo para sua preparaÇço e seu uso como medicamentos
EP2061767B1 (de) 2006-08-08 2014-12-17 Sanofi Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung
MX2009005908A (es) 2006-12-05 2009-06-16 Janssen Pharmaceutica Nv Derivados novedosos de diaza-espiro-piridinona sustituidos para usarse en las enfermedades mediadas por la hormona concentradora de melanina 1.
US8470841B2 (en) 2008-07-09 2013-06-25 Sanofi Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
DE102008049675A1 (de) 2008-09-30 2010-04-01 Markus Dr. Heinrich Verfahren zur Herstellung von 3-Aminobiphenylen
EP2348857B1 (en) 2008-10-22 2016-02-24 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
AU2009309037A1 (en) 2008-10-31 2010-05-06 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
CN102482312A (zh) 2009-08-26 2012-05-30 赛诺菲 新颖的杂芳族氟代糖苷结晶水合物、含有这些化合物的药物和它们的用途
US8895596B2 (en) 2010-02-25 2014-11-25 Merck Sharp & Dohme Corp Cyclic benzimidazole derivatives useful as anti-diabetic agents
MY159058A (en) 2011-02-25 2016-12-15 Merck Sharp & Dohme Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agent
EP2683702B1 (de) 2011-03-08 2014-12-24 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120056A1 (de) 2011-03-08 2012-09-13 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8846666B2 (en) 2011-03-08 2014-09-30 Sanofi Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
EP2683703B1 (de) 2011-03-08 2015-05-27 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120053A1 (de) 2011-03-08 2012-09-13 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120051A1 (de) 2011-03-08 2012-09-13 Sanofi Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
RU2465895C1 (ru) * 2011-09-08 2012-11-10 Государственное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарева" Способ лечения депрессивного невроза
EP2880028B1 (en) 2012-08-02 2020-09-30 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
JP2016516004A (ja) 2013-02-22 2016-06-02 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 抗糖尿病二環式化合物
WO2014139388A1 (en) 2013-03-14 2014-09-18 Merck Sharp & Dohme Corp. Novel indole derivatives useful as anti-diabetic agents
ES2761571T3 (es) 2013-06-20 2020-05-20 Bayer Cropscience Ag Derivados de arilsulfuro y arilsulfóxido como acaricidas e insecticidas
WO2015051496A1 (en) 2013-10-08 2015-04-16 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
WO2016100823A1 (en) 2014-12-19 2016-06-23 The Broad Institute, Inc. Dopamine d2 receptor ligands
US10633336B2 (en) 2014-12-19 2020-04-28 The Broad Institute, Inc. Dopamine D2 receptor ligands
US11072602B2 (en) 2016-12-06 2021-07-27 Merck Sharp & Dohme Corp. Antidiabetic heterocyclic compounds
US10968232B2 (en) 2016-12-20 2021-04-06 Merck Sharp & Dohme Corp. Antidiabetic spirochroman compounds
EP3902805A4 (en) 2018-12-28 2023-03-01 SPV Therapeutics Inc. CYCLINE-DEPENDENT KINASE INHIBITORS

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
EP0002649A3 (en) * 1977-12-19 1979-07-11 Sandoz Ag 1-dimethyl-substituted alkyl-2- or 4-substituted phenylimidazoles, their production and their use as anti-obesity agents
DE4107857A1 (de) * 1991-03-12 1992-09-17 Thomae Gmbh Dr K Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
WO1996025410A1 (en) * 1995-02-17 1996-08-22 Takeda Chemical Industries, Ltd. Azole compounds, their production and use
FR2764889B1 (fr) * 1997-06-20 2000-09-01 Sod Conseils Rech Applic Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
EP1066262A4 (en) * 1998-03-25 2004-09-01 Bristol Myers Squibb Co IMIDAZOLONE ANOREXIGENAL AGENTS: ACYCLIC DERIVATIVES I
JP2002003370A (ja) * 1999-09-20 2002-01-09 Takeda Chem Ind Ltd メラニン凝集ホルモン拮抗剤
AU2001279294A1 (en) * 2000-07-06 2002-01-21 Neurogen Corporation Melanin concentrating hormone receptor ligands
BR0112856A (pt) * 2000-07-31 2003-07-01 Smithkline Beecham Plc Método para o tratamento dos distúrbios, composto ou um sal ou solvato deste, processo para a preparação dos mesmos, composição farmacêutico, método de tratamento e/ou profilaxia de um ou mais dos distúrbios, uso de um composto, e, método para o tratamento de diabetes, grande depressão, depressão manìaca, ansiedade, esquizofrenia e distúrbios do sono, em mamìferos humanos e não humanos
GT200100147A (es) * 2000-07-31 2002-06-25 Derivados de imidazol
YU52403A (sh) * 2000-12-26 2006-03-03 Dr.Reddy's Research Foundation Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže
GB0200283D0 (en) * 2002-01-08 2002-02-20 Smithkline Beecham Plc Compounds

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