JP2006500422A - 酵素活性を阻害するためのキレート化剤の親油性ジエステル - Google Patents

酵素活性を阻害するためのキレート化剤の親油性ジエステル Download PDF

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JP2006500422A
JP2006500422A JP2004539399A JP2004539399A JP2006500422A JP 2006500422 A JP2006500422 A JP 2006500422A JP 2004539399 A JP2004539399 A JP 2004539399A JP 2004539399 A JP2004539399 A JP 2004539399A JP 2006500422 A JP2006500422 A JP 2006500422A
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mmp
disease
bapta
ethane
bis
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ストライム、サリーナ
フリードマン、ジョナサン、エドゥアルト
− コーエン、ダリア レゼニツスキー
コザック、アレクサンダー
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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JP2004539399A 2002-09-25 2003-03-16 酵素活性を阻害するためのキレート化剤の親油性ジエステル Pending JP2006500422A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL15192102A IL151921A0 (en) 2002-09-25 2002-09-25 Liphopilic diesters of chelating agent for inhibition of enzyme activity
PCT/IL2003/000225 WO2004028443A2 (en) 2002-09-25 2003-03-16 Lipophilic diesters of chelating agent for inhibition of enzyme activity

Publications (2)

Publication Number Publication Date
JP2006500422A true JP2006500422A (ja) 2006-01-05
JP2006500422A5 JP2006500422A5 (https=) 2006-04-06

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ID=29596515

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Application Number Title Priority Date Filing Date
JP2004539399A Pending JP2006500422A (ja) 2002-09-25 2003-03-16 酵素活性を阻害するためのキレート化剤の親油性ジエステル

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Country Link
US (1) US7799831B2 (https=)
EP (1) EP1546085B1 (https=)
JP (1) JP2006500422A (https=)
AU (1) AU2003214610C1 (https=)
CA (1) CA2498420C (https=)
IL (2) IL151921A0 (https=)
WO (1) WO2004028443A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0508412D0 (en) * 2005-04-26 2005-06-01 Aq & Plc Compositions for intestinal conditions
US9415032B2 (en) 2011-10-05 2016-08-16 The Johns Hopkins University Membrane activated chelators and use in the prevention and treatment of parasitic infection
CN103373957A (zh) * 2012-04-12 2013-10-30 成都苑东药业有限公司 一种具有神经细胞保护作用的螯合物
US20150196625A9 (en) 2013-01-07 2015-07-16 Rudolph D. Paladini Metal Sensitive Mutants of Matrix Metalloproteases and uses thereof
WO2018236221A2 (en) * 2017-06-03 2018-12-27 Can Holding B.V. Neurodegenerative peptide deposit dissolution

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413949B1 (en) * 1995-06-07 2002-07-02 D-Pharm, Ltd. Prodrugs with enhanced penetration into cells
AU2829395A (en) 1994-06-16 1996-01-05 Allergan, Inc. Method for reducing intraocular pressure in the mammalian eye by administration of calcium chelators
WO1997009976A2 (en) * 1995-09-01 1997-03-20 Washington University Method of reducing neurotoxic injury with zinc chelators
IL121844A0 (en) 1997-09-28 1998-02-22 Dpharm Ltd Lipophilic diesters of chelating agents
WO2002047674A2 (en) 2000-11-08 2002-06-20 Thomas Jefferson University Use of intracellular calcium chelators (e.g bapta-am) to increase surfactant secretion in the lungs

Also Published As

Publication number Publication date
EP1546085A2 (en) 2005-06-29
IL151921A0 (en) 2003-04-10
IL167406A0 (en) 2009-02-11
WO2004028443A3 (en) 2004-05-27
EP1546085B1 (en) 2012-09-05
AU2003214610B2 (en) 2008-08-21
WO2004028443A2 (en) 2004-04-08
AU2003214610A1 (en) 2004-04-19
US7799831B2 (en) 2010-09-21
CA2498420C (en) 2012-07-10
IL167406A (en) 2012-04-30
US20060167092A1 (en) 2006-07-27
EP1546085A4 (en) 2008-03-26
CA2498420A1 (en) 2004-04-08
AU2003214610C1 (en) 2009-01-22

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