JP2006500002A5 - - Google Patents
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- Publication number
- JP2006500002A5 JP2006500002A5 JP2003548687A JP2003548687A JP2006500002A5 JP 2006500002 A5 JP2006500002 A5 JP 2006500002A5 JP 2003548687 A JP2003548687 A JP 2003548687A JP 2003548687 A JP2003548687 A JP 2003548687A JP 2006500002 A5 JP2006500002 A5 JP 2006500002A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- level
- individual
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 21
- 102000004196 processed proteins & peptides Human genes 0.000 claims 21
- 108090000765 processed proteins & peptides Proteins 0.000 claims 21
- 238000000034 method Methods 0.000 claims 10
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 6
- 206010012601 diabetes mellitus Diseases 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 210000004153 islets of langerhan Anatomy 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 102000004877 Insulin Human genes 0.000 claims 2
- 108090001061 Insulin Proteins 0.000 claims 2
- 229940125396 insulin Drugs 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33663301P | 2001-12-03 | 2001-12-03 | |
| PCT/US2002/038556 WO2003047421A2 (en) | 2001-12-03 | 2002-12-02 | Methods and reagents for diagnosis and treatment of diabetes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006500002A JP2006500002A (ja) | 2006-01-05 |
| JP2006500002A5 true JP2006500002A5 (enExample) | 2006-02-16 |
Family
ID=23316971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003548687A Pending JP2006500002A (ja) | 2001-12-03 | 2002-12-02 | 糖尿病の診断および治療のための方法および試薬 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7144985B2 (enExample) |
| EP (1) | EP1461351A4 (enExample) |
| JP (1) | JP2006500002A (enExample) |
| AU (1) | AU2002351214B2 (enExample) |
| CA (1) | CA2468991A1 (enExample) |
| WO (1) | WO2003047421A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7054758B2 (en) | 2001-01-30 | 2006-05-30 | Sciona Limited | Computer-assisted means for assessing lifestyle risk factors |
| AU2002306853B2 (en) * | 2001-03-15 | 2006-07-06 | Research Development Foundation | Urocortin-III and uses thereof |
| WO2009045370A2 (en) | 2007-09-28 | 2009-04-09 | Intrexon Corporation | Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof |
| CA2742710A1 (en) * | 2008-11-04 | 2010-05-14 | Janssen Pharmaceutica Nv | Crhr2 peptide agonists and uses thereof |
| EP2584041A1 (en) * | 2011-10-21 | 2013-04-24 | Industrial Cooperation Foundation Chonbuk National University | Composition for preventing or treating diabetes comprising nad glycohydrolase inhibitor as active ingredient |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020082409A1 (en) | 2000-10-26 | 2002-06-27 | Hsu Sheau Yu | Stresscopins and their uses |
| AU2002306853B2 (en) | 2001-03-15 | 2006-07-06 | Research Development Foundation | Urocortin-III and uses thereof |
-
2002
- 2002-12-02 CA CA002468991A patent/CA2468991A1/en not_active Abandoned
- 2002-12-02 JP JP2003548687A patent/JP2006500002A/ja active Pending
- 2002-12-02 EP EP02786860A patent/EP1461351A4/en not_active Withdrawn
- 2002-12-02 AU AU2002351214A patent/AU2002351214B2/en not_active Ceased
- 2002-12-02 US US10/308,393 patent/US7144985B2/en not_active Expired - Fee Related
- 2002-12-02 WO PCT/US2002/038556 patent/WO2003047421A2/en not_active Ceased
-
2006
- 2006-11-01 US US11/591,992 patent/US7294698B2/en not_active Expired - Fee Related
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