JP2006321943A - Simulated tobacco smell composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a simulated tobacco smell composition which can accurately reproduce a tobacco smell and enables the suitable evaluation of an effect for deodorizing, masking or modulating the tobacco smell, and to provide a method for evaluating the effect for deodorizing, masking or modulating the tobacco smell with the simulated tobacco smell composition. <P>SOLUTION: This simulated tobacco smell composition containing methoxyphenol. Preferably, the simulated tobacco smell composition furthermore containing vinylpyridine and/or ethylpyridine. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention is a pseudo-tobacco odor composition that can more accurately reproduce the odor of smoke generated when smoking, the so-called tobacco odor, and can suitably evaluate the deodorizing effect, masking effect, or modulation effect on the tobacco odor, and uses the same The present invention relates to a method for evaluating the deodorization, masking or modulation effect of tobacco odor.

  In recent years, the odor of kitchens, baths and toilets has been reduced due to the improvement of the housing environment, the odor in the home has been decreasing, and the increase in health-consciousness has increased the number of people who are concerned about tobacco odor. Demand for deodorizing tobacco odors attached to rooms and clothing is increasing year by year.

  Under such circumstances, it is important to develop a product that has a higher deodorizing effect, masking effect, or modulation effect of tobacco odor and has an immediate effect. Conventionally, in order to evaluate the deodorizing effect, masking effect or modulation effect on the tobacco odor of a compound or composition to be evaluated (hereinafter referred to as “subject”), the tobacco is actually smoked and odor is attached to the cloth. A tobacco odor test sample was prepared. However, with this method, there is a problem that the strength and quality of odors differ every time a test sample of tobacco odor is produced, and there is a tendency for odors to evaporate when produced and stored in large quantities at once, and storage is difficult There was a problem.

  It is said that there are about 2,000 kinds of odor components of tobacco smoke. Non-patent document 1 reports nitrogen-containing compounds contained in tobacco and tobacco smoke, and non-patent document 2 discloses cigarettes. The mainstream smoke component has been reported. However, none of the reports mentions which components are important as odor components.

  Non-Patent Document 3 reports that ammonia, acetaldehyde, acetic acid, hydrogen sulfide, and pyridine are used for quantitatively measuring the deodorizing effect of the deodorizing fiber. It is a component selected from the viewpoint of ease of quantification, and it is not stated which component is important as an odor component, and even if these components are combined, it is not always satisfactory as a pseudo-tobacco odor composition It did not become a level.

Chemical Reviews Vol.77, No.3, p.295-310, 1977 Agric. Biol. Chem., 42 (2), 407-410, 1978 Japan Textile Products Consumer Science Vol.40, No.1, p.45-51, 1999

  Under such circumstances, there has been a demand for a method capable of evaluating the deodorizing effect, masking effect or modulation effect on tobacco odor more quickly, efficiently and accurately. In order to realize this, it is essential to develop a pseudo tobacco odor composition for evaluation that can easily produce a tobacco odor test sample having the same strength and quality of odor.

  An object of the present invention is a pseudo-tobacco odor composition that can more accurately reproduce smoke generated when smoking, so-called tobacco odor, and can suitably evaluate the deodorizing effect, masking effect, or modulation effect of tobacco odor, and uses the same. It is providing the evaluation method of the deodorizing, masking, or modulation effect with respect to a tobacco odor.

  Here, in the present invention, the deodorizing effect means a physical / chemical deodorizing effect using a deodorizing base, and the masking effect means a sensory deodorizing effect using a scent stronger than a bad odor. The modulation effect means an effect of changing the impression of bad odor quality using a scent.

  The present inventors collect the sidestream smoke and discharged smoke of tobacco and use the AEDA (Aroma Extract Dilution Analysis) method, and among the odor components contained in tobacco smoke, the most tobacco It was clarified that the component with odorous smell was 2-methoxyphenol and then 3-vinylpyridine. As a result of examination based on this finding, the present inventors succeeded in obtaining a pseudo tobacco odor composition that can reproduce the actual tobacco odor more accurately.

  Furthermore, the present inventors investigated the odor of analogs of 2-methoxyphenol and 3-vinylpyridine, and as a result, 3-methoxyphenol and 4-methoxyphenol, which are analogs of 2-methoxyphenol, were found to be 2-methoxyphenol. 2-vinylpyridine, 4-vinylpyridine, 2-ethylpyridine, 3-ethylpyridine and 4-ethylpyridine, which are analogs of 3-vinylpyridine, have the same effect as phenol. It has been found that the same effect is obtained, and the present invention has been completed.

  That is, the present invention provides a pseudo-tobacco odor composition containing methoxyphenol, and a method for evaluating the deodorizing effect, masking effect or modulation effect on tobacco odor using the same.

  According to the present invention, since the tobacco odor can be reproduced more accurately, the deodorizing effect, masking effect or modulation effect of the subject can be simply and efficiently evaluated accurately by using this, It contributes greatly to the development of deodorant-related products.

  The pseudo tobacco odor composition of the present invention contains methoxyphenol as an essential component, and methoxyphenol alone may be used. Examples of methoxyphenol include 2-methoxyphenol (Guaiacol), 3-methoxyphenol, and 4-methoxyphenol, with 2-methoxyphenol being particularly preferable. Any of these methoxyphenols can be used alone, or two or three of them can be used.

  Moreover, the pseudo tobacco odor composition of the present invention may further contain vinyl pyridine and / or ethyl pyridine. Examples of vinyl pyridine include 2-vinyl pyridine, 3-vinyl pyridine, and 4-vinyl pyridine. Examples of ethyl pyridine include 2-ethyl pyridine, 3-ethyl pyridine, and 4-ethyl pyridine. Of these, 2 -Vinylpyridine and 3-vinylpyridine are particularly preferred. These vinyl pyridines and ethyl pyridines can also be used alone or in combination of two or more.

  The mass ratio (a) / (b) of the content of (a) methoxyphenol and (b) vinylpyridine and / or ethylpyridine is preferably 100/0 to 10 / from the viewpoint of similarity to tobacco odor. 90, more preferably 80/20 to 40/60, particularly preferably 60/40 to 40/60.

  In addition to vinyl pyridine, known tobacco odor components such as acetic acid, ammonia, pyridine, acetaldehyde, nicotine and the like may be added.

  From the viewpoint of handleability, the simulated tobacco odor composition of the present invention is a solvent such as water, ethanol, triethyl citrate, acetone, dipropylene glycol, liquid paraffin, LPG (liquefied petroleum gas) as a diluent, cationic, Anionic, nonionic and amphoteric surfactants can be included.

  In the simulated tobacco odor composition of the present invention, the content of methoxyphenol is preferably 0.001 to 100% by mass, more preferably 0.01 to 100% by mass, and the content of vinylpyridine or ethylpyridine is preferably 0 to 100% by mass. 90 mass%, more preferably 0.0001-80 mass%, still more preferably 0.0001-60 mass%.

  When the simulated tobacco odor composition of the present invention is used as a model of tobacco odor in the space immediately after smoking, the content of methoxyphenol is 10 to 100% by mass, and the content of vinylpyridine and / or ethylpyridine is 0. It is preferable to use about 1 to 100 mg of ˜90 mass% pseudo deodorant composition of the present invention.

  When the pseudo tobacco odor composition of the invention is used as a model of tobacco odor attached to clothing and hair, the content of methoxyphenol is 0.01 to 0.5% by mass, and the content of vinylpyridine and / or ethylpyridine is 0.01 to It is preferable to use about 0.1 to 10 g of 0.5% by mass of the pseudo tobacco odor composition of the present invention.

  When the simulated tobacco odor composition of the invention is used as a model of a weak tobacco odor remaining on the wallpaper of a vehicle or a smoking room, the content of methoxyphenol is 0.001 to 0.01% by mass, vinylpyridine and / or ethylpyridine. It is preferable to use about 10 to 1000 g of the pseudo-tobacco odor composition of the present invention having a content of 0.001 to 0.01% by mass.

  The simulated tobacco odor composition of the present invention can be used as it is or impregnated in a solid carrier. The solid carrier is not particularly limited as long as it can carry the pseudo-tobacco odor composition. For example, silica gel, activated carbon, hydroxyapatite, alumina, zeolite, diatomaceous earth, clay mineral, cyclodextrin, talc, calcium carbonate, gel Agent, cellulose and derivatives thereof, paper, nonwoven fabric, fiber, resin (polypropylene, polyethylene, polyester, nylon, polyurethane, polyvinyl, polyvinylidene, ethylene-polyvinyl alcohol copolymer, polystyrene, polyacrylate, allylstyrene copolymer) Etc. The form of the solid carrier is not particularly limited, and for example, it can be used as powder, granules, sheets, lumps and the like.

(1) Simulated tobacco odor composition <Examples 1-14, Comparative Examples 1-6>
Ingredients shown in Table 1 were mixed in a 20 mL glass bottle to a total of 200 mg, and 3 specialist panels evaluated the similarity to tobacco odor and the strength of odor based on the evaluation criteria shown below. Conducted and judged by consultation. The evaluation results are shown in Table 1.

<Evaluation criteria for similarity to tobacco odor>
◎: Very similar (burnt cigarette odor, smoker's clothes, breath-like odor)
○: Very similar (burnt cigarette smell)
Δ: Somewhat not similar ×: Not at all similar

<Evaluation criteria for odor strength>
◎: Very strong ○: Strong △: Weak ×: Very weak

Example 1 using 2-methoxyphenol alone and Examples 2 to 11 combining 2-methoxyphenol and 2-vinylpyridine or 3-ethylpyridine are very similar to tobacco odors. 7 and Example 11 were very similar to tobacco odor. Examples 1 to 11 also had a strong odor and could be sufficiently used as a pseudo-tobacco odor. In addition, Examples 12 to 14 in which acetic acid, ammonia, pyridine, and acetaldehyde were used in combination with 2-methoxyphenol and 2-vinylpyridine and acetic acid, ammonia, pyridine, and acetaldehyde, which are conventionally used as indicators of the deodorizing effect, also had a It was a level that was sufficiently usable as a simulated tobacco odor.
In contrast, Comparative Example 1 using 2-vinylpyridine alone, although somewhat similar to tobacco odor, was not at a usable level as a simulated tobacco odor.

  The result of having examined about the substance conventionally used for the measurement of the deodorizing effect of a deodorizing fiber is shown as Comparative Examples 2-6. Acetic acid alone (Comparative Example 2) does not resemble a sour odor. Ammonia alone (Comparative Example 3) does not resemble an exciting ammonia odor. Pyridine alone (Comparative Example 4) does not resemble an irritating, lively solvent-like odor. Acetaldehyde alone (Comparative Example 5) does not resemble the fermentation odor. Nicotine alone (Comparative Example 6) is somewhat weak but very similar to tobacco odor. From the above, none of Comparative Examples 2 to 6 was at a usable level as a pseudo-tobacco odor.

(2) Evaluation of deodorizing effect using simulated tobacco odor composition 1
2-1. Preparation of test sample
A composition (Example 5) of 2-methoxyphenol / 2-vinylpyridine = 6/4 (mass ratio) was dissolved in ethanol to obtain a 0.1 mass% solution. After impregnating 0.3 g on a 30 cm x 35 cm cotton cloth with a spray, leave it for 10 minutes to eliminate ethanol and make a tobacco odor test cloth.

2-2. Preparation of deodorant Green tea extract (FS-500M, manufactured by Shiraimatsu Shinyaku) in water-ethanol (85% by mass / 15% by mass) 5% by mass

2-3. Evaluation standard of odor strength The following 6-step odor intensity display method (standard in the malodor control method) was used.

5: Strong odor 4: Strong odor 3: Easily perceived scent 2: Weak scent that understands what scent is 1: Scent that can finally be perceived 0: Odorless

2-4. Deodorization test
Two sheets of the tobacco odor test cloth prepared in 2-1 were prepared. On the other hand, the deodorant prepared in 2-2 was sprayed 24 times and allowed to stand for 10 minutes, and then the tobacco odor was evaluated.
As a result, the odor strength of the test cloth that was not sprayed with the deodorant was 3, but the odor strength of the test cloth that was sprayed with the deodorant was lowered to 2, which was used to evaluate the deodorant effect. It was judged that this was suitable as a pseudo-tobacco odor composition and deodorant evaluation method.

(3) Evaluation of deodorizing effect using simulated tobacco odor composition 2
Using a composition (Example 11) of 2-methoxyphenol / 3-ethylpyridine = 6/4 (mass ratio) as a test sample, (2) Evaluation 1 of deodorizing effect using the simulated tobacco odor composition and When the same deodorant effect was evaluated according to the same criteria, the odor of the test cloth that was not sprayed with the deodorant was 3, but the odor of the test cloth that was sprayed with the deodorant was strength. Was determined to be suitable as a pseudo-tobacco odor composition for evaluating the deodorizing effect and a method for evaluating deodorization.

(4) Evaluation of deodorizing effect using simulated tobacco odor composition 3
4-1. Preparation of test sample
A filter paper having a width of 7 mm, a length of 15 cm and a thickness of 1 mm was impregnated with 10 mg of a composition of 2-methoxyphenol / 2-vinylpyridine = 6/4 (mass ratio) to prepare a tobacco odor test sample.

4-2. Preparation of masking agent A filter paper having a width of 7 mm, a length of 15 cm and a thickness of 1 mm was impregnated with 50 mg of orange oil to prepare a deodorant sample.

4-3. Deodorization test Prepare two sealed spaces with a width of 1.2m, a depth of 1.2m, and a height of 2.4m, and sandwich the cigarette odor test sample prepared in 3-1 with a clip at the bottom of both spaces. Install. Next, the deodorant sample prepared in 3-2 is fixed to a clip and placed in one space. After 30 minutes, the odor intensity of the space was evaluated.
As a result, the odor intensity in the space where the deodorant sample was not installed was 3, but the odor intensity in the space where the deodorant sample was installed was lowered to 2, and the masking effect by the fragrance was evaluated. It was judged to be suitable as a simulated tobacco odor composition and masking evaluation method.

Claims (6)

  A simulated tobacco odor composition containing methoxyphenol.   The pseudo-tobacco odor composition according to claim 1, further comprising vinylpyridine and / or ethylpyridine.   The pseudo-tobacco odor composition according to claim 2, wherein the mass ratio (a) / (b) of the content of (a) methoxyphenol and (b) vinylpyridine and / or ethylpyridine is 100/0 to 10/90. object.   The simulated tobacco odor composition according to any one of claims 1 to 3, wherein the methoxyphenol is 2-methoxyphenol.   The simulated tobacco odor composition according to any one of claims 2 to 4, wherein the vinylpyridine is 2-vinylpyridine or 3-vinylpyridine.   The evaluation method of the deodorizing effect, masking effect, or modulation effect with respect to tobacco odor using the pseudo tobacco odor composition in any one of Claims 1-5.