JP2006282539A - Cosmetic base and cosmetic compounded with the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a cosmetic base which has both an excellent touch and a high moisture-retaining property and has excellent compatibility with oily ingredients, and to provide a cosmetic compounded with the same. <P>SOLUTION: This cosmetic base comprises an alkylene oxide derivative represented by the following formula (I): Z-äO(AO)<SB>l</SB>(EO)<SB>m</SB>-(BO)<SB>n</SB>H}<SB>a</SB>[Z is the hydroxy group-removed residue of a compound having three to nine hydroxy group; (a) is 3 to 9; AO is a 3 or 4C oxyalkylene; EO is oxyethylene; (l) and (m) are the average addition moles of the 3 or 4C oxyalkylene and the oxyethylene groups, respectively, wherein 1≤(l)≤50, and 1≤(m)≤50; the (AO/EO) weight ratio of AO/EO is 1/5 to 5/1; AO and EO may be added in a random or block state; BO is a 4C oxyalkylene; (n) is its average addition moles, wherein 5<(n)≤30]. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to a cosmetic base that has both excellent feel such as a smooth feeling and a moist feeling and moisturizing properties, and has excellent blending stability in an oily preparation, and a cosmetic blended with the same.

As a recent consumer trend, cosmetics tend to be preferred to have a lighter touch, and there is a demand for cosmetics that are refreshing or smooth and that have a good moisturizing effect.
In general, a moisturizing agent is blended for the purpose of imparting a moisturizing effect. Most of the moisturizers are water-soluble polyhydric alcohols typified by glycerin, propylene glycol, 1,3-butylene glycol, and polyethylene glycol. In addition, oily preparations such as water-in-oil type emulsified cosmetics and oily cosmetics cannot be highly blended in terms of stability.
Therefore, in order to impart a moisturizing effect in oily preparations, hydrocarbons such as squalane and petrolatum, fats and oils such as olive oil and jojoba oil, and sterols such as cholesterol are often used as oily moisturizing agents. These oil-based moisturizers have a better feeling of use than water-soluble polyhydric alcohols, but they are inferior in the moisturizing effect and require a large amount of emulsifier when blended to increase the moisturizing effect. As a result, the feeling of smoothness decreases. That is, there is a demand for the development of a cosmetic base that has a good moisturizing effect and a smooth feeling in an oily preparation and that can be highly blended.
Under such circumstances, in order to give both the moisturizing feeling and the smooth feeling in the oily preparation, a combination of a polyglycerin higher fatty acid ester and a nonionic surfactant (for example, Patent Documents 1 and 2), N-long chain An acyl-neutral amino acid alkyl or alkenyl ester (for example, Patent Document 3), a combination of a polyoxyalkylene-added alkyl glucoside and a lipophilic polyoxyalkylene-modified silicone (for example, Patent Document 4), and the like have been disclosed. The present situation is that the effect is not acquired.

Japanese Patent Laid-Open No. 9-208444 JP-A-6-219923 JP 2000-355331 A JP-A-10-29912

  An object of the present invention is to provide a cosmetic base having both excellent feel and high moisturizing property and excellent compatibility with an oil component, and a cosmetic containing the same.

That is, the present invention is as follows.
(1) A cosmetic base comprising an alkylene oxide derivative represented by the following formula (I).
Z- {O (AO) _l (EO) _m- (BO) _n H} _a (I)
(Wherein Z is a residue excluding the hydroxyl group of the compound having 3 to 9 hydroxyl groups, a is 3 to 9, AO is an oxyalkylene group having 3 to 4 carbon atoms, EO is an oxyethylene group, l and m Are the average addition moles of oxyalkylene groups having 3 to 4 carbon atoms and oxyethylene groups, 1 ≦ l ≦ 50, 1 ≦ m ≦ 50, and the weight ratio of AO to EO (AO / EO) is 1. AO and EO may be added in a random or block form, BO is an oxyalkylene group having 4 carbon atoms, n is the average number of moles added, and 5 < n ≦ 30.)
(2) A cosmetic base comprising the above-mentioned alkylene oxide derivative in which AO and EO are randomly added.
(3) A cosmetic comprising the cosmetic base described above.
(4) The cosmetic described above containing 0.01 to 50% by weight of a cosmetic base and 0.1 to 80% by weight of an oil component.
(5) The cosmetic described above containing a humectant in an amount of 0.01 to 30% by weight.

  The cosmetic base of the present invention has both an excellent feel such as a smooth feeling and a moist feeling, a moisturizing feeling, can be stably blended in an oily preparation, and exhibits good performance when blended in a cosmetic. A base and a cosmetic comprising the same.

  In the alkylene oxide derivative represented by the formula (I), Z is a residue excluding the hydroxyl group of the compound having 3 to 9 hydroxyl groups, and a is the number of hydroxyl groups of the compound of Z and 3 to 9. As a compound having 3 to 9 hydroxyl groups, for example, if a = 3, glycerin, trimethylolpropane, if a = 4, erythritol, pentaerythritol, sorbitan, alkylglycoside, diglycerin, a = 5 Examples include xylitol, dipentaerythritol, sorbitol, inositol if a = 6, sucrose, trehalose if a = 8, maltitol if a = 9, and mixtures thereof. Z is preferably a residue excluding the hydroxyl group of the compound having 3 to 6 hydroxyl groups, and satisfies 3 ≦ a ≦ 6. In a <= 2, there exists a tendency for the mixing | blending stability to an oil-based formulation to deteriorate that it is inferior to compatibility with oily components, such as fats and oils. When 10 ≦ a, a sticky feeling is generated, and the desired effect cannot be obtained.

AO is an oxyalkylene group having 3 to 4 carbon atoms, and examples thereof include an oxypropylene group, an oxybutylene group, an oxyisobutylene group, an oxytrimethylene group, and an oxytetramethylene group. An oxypropylene group, an oxybutylene group, and more preferably an oxypropylene group.
l is the average added mole number of AO, and 1 ≦ l ≦ 50, preferably 2 ≦ l ≦ 20. m is an average added mole number of EO, and 1 ≦ m ≦ 50, preferably 2 ≦ m ≦ 20. If l is 0, a sticky feeling is produced, and if it exceeds 50, the moisturizing effect is lowered. Further, if m is 0, the moisturizing effect is lowered, and if it exceeds 50, a sticky feeling is produced.

The weight ratio (AO / EO) between AO and EO is 1/5 to 5/1, preferably 1/4 to 4/1. If it is less than 1/5, a sticky feeling is produced, and if it is greater than 5/1, the moisturizing feeling is lowered.
The order in which AO and EO are added is not particularly specified, and they may be added in blocks or randomly. Preferably, it is added randomly.

BO is an oxyalkylene group having 4 carbon atoms, and examples thereof include an oxybutylene group, an oxyisobutylene group, and an oxytetramethylene group. An oxybutylene group is preferred.
n is the average added mole number of BO, 5 <n ≦ 30, preferably 6 ≦ n ≦ 20. If it is 5 or less, the hydrophilicity becomes strong and the compatibility with the oil component is poor, and if it exceeds 30, the intended moisturizing effect cannot be obtained.
The total of the average added mole number 1 of AO and the average added mole number BO of the present invention is preferably 6 ≦ l + n ≦ 50, more preferably 8 ≦ l + n ≦ 40.

The alkylene oxide derivative represented by the formula (I) of the present invention can be produced by a known method. For example, it can be obtained by subjecting a compound having 3 to 9 hydroxyl groups to addition polymerization of ethylene oxide and an alkylene oxide having 3 to 4 carbon atoms and then reacting the alkylene oxide having 4 carbon atoms.
Further, the form of the cosmetic comprising the cosmetic base of the present invention is in particular a water-in-oil emulsified cosmetic and an oily cosmetic, and more specifically, a moisturizing cosmetic and a cleansing cosmetic. Hair cosmetics, makeup cosmetics, etc.

The amount of the cosmetic base in the cosmetic of the present invention is not particularly limited, but is usually 0.01 to 80% by weight.
Moreover, the cosmetic of this invention becomes a thing with both favorable touch and moisture retention by mix | blending an oil-based component. Preferably 0.01 to 50% by weight of the base of the present invention and 0.01 to 80% by weight of the oily component, more preferably 0.1 to 30% by weight of the base of the present invention and 0.1 to 70% by weight of the oily component. %, More preferably a combination of 1 to 20% by weight of the base of the present invention and 1 to 50% by weight of an oily component is effective. If the base of the present invention is more than 50% by weight and the oil component is more than 80% by weight, a sticky feeling may occur, which is not preferable.

  As an oily component, the component normally used for cosmetics can be contained. Examples of such components include petrolatum, squalane, squalene, microcrystalline wax, liquid paraffin, liquid isoparaffin, polyisobutene, ceresin and other hydrocarbons; hexyl alcohol, heptyl alcohol, octyl alcohol, nonyl alcohol, decyl alcohol, undecyl Alcohol, dodecyl alcohol, lauryl alcohol, tridecyl alcohol, myristyl alcohol, cetyl alcohol, cetostearyl alcohol, isocetyl alcohol, oleyl alcohol, stearyl alcohol, isostearyl alcohol, aralkyl alcohol, behenyl alcohol, jojoba alcohol, octyldodeca Alcohols having 6 or more carbon atoms, such as diol and hexyldecanol; Acid, 2-ethylhexanoic acid, lauric acid, myristic acid, myristic acid, coconut oil fatty acid, beef tallow fatty acid, palm oil fatty acid, palmitic acid, palmitoleic acid, stearic acid, oleic acid, isostearic acid, linoleic acid, linolenic acid Fatty acids having 6 or more carbon atoms such as arachidic acid, behenic acid, arachidonic acid and erucic acid, and triglycerides thereof; diethyl sebacate, cetyl 2-ethylhexanoate, isocetyl 2-ethylhexanoate, isopropyl palmitate, palmitic acid 2-ethylhexyl, isopropyl isostearate, 2-hexyldecyl isostearate, isostearyl isostearate, trimethylpropane triisostearate, octyldodecyl myristate, isopropyl myristate, isomyristate Ester oil such as teal, isocetyl myristate, hexyl laurate, ethyl oleate, isostearyl pivalate, isopropyl isostearate, isononyl isononanoate, 2-ethylhexyl isononanoate, isodecyl isononanoate, isotridecyl isononanoate, neopentyl glycol didecanoate Olive oil, corn oil, peanut oil, rapeseed oil, sesame oil, soybean oil, palm oil, palm oil, palm kernel oil, castor oil, flaxseed oil, jojoba oil, sunflower oil, macadamia nut oil, tea seed oil, cottonseed oil, perilla oil Animal and vegetable oils such as safflower oil, kyounin oil, beef tallow, lard, etc .; silicones such as linear and cyclic dimethylpolysiloxane and polyether modified silicone; cholesterol, sitosterol, campesterol, stigmaster Examples thereof include sterols such as rolls, brush castrol and phytosterols. Preferred are hydrocarbons, triglycerides having 6 to 24 carbon atoms, animal and vegetable oils, ester oils and sterols. Moreover, you may use these 1 type, or 2 or more types.

  The cosmetic of the present invention further enhances the moisturizing effect by blending a moisturizing agent. Preferably it is 0.01-30 weight%, More preferably, it is 1-10 weight%. If it exceeds 30% by weight, a sticky feeling may appear, which is not preferable. As the humectant, any component usually used in cosmetics can be contained. Examples of such optional components include glycerin, diglycerin, polyglycerin, 1,3-butylene glycol, 3-methyl-1,3-butylene glycol, ethylene glycol, diethylene glycol, polyethylene glycol, propylene glycol, and dipropylene glycol. , Glucose, polypropylene glycol, sorbitol, xylitol, trehalose, maltitol, mannitol, chitosan, urea, sodium hyaluronate, sodium pyrrolidonecarboxylate, sodium lactate, sodium ribonucleic acid, aspartic acid, sodium alginate, alanine, glycine, cystine, cysteine , Serine, arginine, lysine, ashitaba extract, altea extract, aloe extract, oyster extract, seaweed extract, carinje Vinegar, raspberry extract, cucumber extract, quince seed extract, Zegna Oy extract, placenta extract, loofah extract, Yuriekisu, apple extract, royal jelly, such as lactoferrin, and the like. Preferred are glycerin, 1,3-butylene glycol, polyethylene glycol, propylene glycol, and sorbitol, and one or more of these can be used.

In the cosmetics of the present invention, various components generally used in cosmetics, pharmaceuticals, etc., that is, vitamins, UV absorbers, water-soluble substances, as long as they do not impair the effects of the present invention. Examples include polymers, antioxidants, anionic surfactants, cationic surfactants, amphoteric surfactants, nonionic surfactants, sequestering agents, ethanol, thickeners, preservatives, dyes, pigments, and fragrances. .
The cosmetic of the present invention can contain an alkylene oxide derivative represented by the formula (I), an oily component, a moisturizing agent, and other optional components, but the total amount exceeds 100% by weight in the above compounding amount. It can mix | blend in the range which is not.

Synthesis Example 1 Synthesis of polyoxybutylene (48 mol, n = 8) polyoxyethylene (30 mol, m = 5) polyoxypropylene (30 mol, l = 5) sorbitol (a = 6) ether (with polyoxyethylene and (Polyoxypropylene is a block polymer)
After 182 g of sorbitol and 25 g of potassium hydroxide as a catalyst were charged into an autoclave and the air in the autoclave was replaced with dry nitrogen, the catalyst was completely dissolved at 140 ° C. with stirring. Next, 1740 g of propylene oxide was dropped with a dropping device and stirred for 2 hours. Subsequently, 1320 g of ethylene oxide was dropped by a dropping device and stirred for 2 hours. Further, 3456 g of butylene oxide was dropped with a dropping device, and the mixture was stirred for 2 hours to be reacted. Thereafter, the reaction composition was taken out from the autoclave, neutralized with hydrochloric acid to pH 6 to 7, and treated at a reduced pressure of -0.095 MPa (gauge pressure) at 100 ° C for 1 hour in order to remove the contained water. Further, filtration was performed to remove the salt generated after the treatment, and a base of Compound 1 was obtained.

Synthesis Example 2 Synthesis of polyoxybutylene (27 mol, n = 9) polyoxyethylene (10 mol, m = 3.3) polyoxypropylene (10 mol, l = 3.3) glyceryl (a = 3) ether ( Polyoxyethylene and polyoxypropylene are random polymers)
After charging 92 g of glycerin and 25 g of potassium hydroxide as a catalyst into the autoclave and replacing the air in the autoclave with dry nitrogen, the catalyst was completely dissolved at 140 ° C. with stirring. Next, a mixture of 440 g of ethylene oxide and 580 g of propylene oxide was dropped with a dropping device and stirred for 2 hours. Subsequently, 1944 g of butylene oxide was dropped with a dropping device and stirred for 2 hours. Thereafter, the reaction composition was taken out from the autoclave, neutralized with hydrochloric acid to pH 6 to 7, and treated at a reduced pressure of -0.095 MPa (gauge pressure) at 100 ° C for 1 hour in order to remove the contained water. Further, filtration was performed to remove the salt produced after the treatment, and a base of Compound 2 was obtained.
In the same manner as in Synthesis Example 1 or Synthesis Example 2, Compounds 3-6 and Comparative Substances 7-12 according to Claim 1 shown in Table 1 were synthesized.

Examples 1-6 and Comparative Examples 1-6
The compatibility with fats and oils (olive oil), which is widely used in cosmetics, was evaluated. The evaluation method is to prepare a 20% olive oil solution of compounds 1 to 12, stir at 25 ° C., and let stand at the same temperature for 30 minutes, evaluate the following criteria, pass ○ It was.
○: Dissolution △: Dispersion (white turbidity)
X: Separation Table 1 also shows the results.
Examples 1-6 were all acceptable. None of Comparative Examples 1 to 6 had good compatibility.

Examples 7-14 and Comparative Examples 7-15
(A) The compound 1-6 of Claim 1 as a component, (a ') the comparative substance 7-12 as a component, (b) any oily component as a component, (c) any moisturizer as a component, An emulsion was prepared with the composition (% by weight) shown in Table 2 and subjected to sensory evaluation.
<Adjustment method>
Each component was heated to 80 ° C., emulsified by stirring, and then purified water was gradually added at the same temperature while stirring. After cooling to 40 ° C., an emulsion was obtained.

<Sensory evaluation>
Using ten professional panelists, the absence of stickiness (smooth feeling) and the moisturizing feeling of the compounds were evaluated. For the evaluation method, after washing the upper arm portion with soap, an emulsion was applied, and an average value evaluated on a five-point basis for the feeling of stickiness and moisturizing feeling immediately after application to 30 minutes was adopted. A score of 3.5 or higher was judged to be good.
<No stickiness (smooth feeling)>
5: Very good feel and light feel 4: Good feel, light feel 3: Slightly bad feel, a little squeezed feel 2: Slow feel, heavy feel 1: Very bad feel <Moisturizing feeling>
5: There is no bulkiness and it is sufficiently moisturized 4: There is no bulkiness and it is moistened 3: There is a little bulkiness and there is little moisture 2: There is bulkiness and there is no moisture State 1: A state in which the texture is severe and moisture is not sufficient Table 2 also shows the evaluation results.

  From Examples 7 to 14, the base of the present invention satisfies both the points of no stickiness and moisturizing feeling. However, Comparative Examples 7 to 15 do not satisfy the two properties at the same time.

Claims (5)

A cosmetic base comprising an alkylene oxide derivative represented by the following formula (I):
Z- {O (AO) _l (EO) _m- (BO) _n H} _a (I)
(Wherein Z is a residue excluding the hydroxyl group of the compound having 3 to 9 hydroxyl groups, a is 3 to 9, AO is an oxyalkylene group having 3 to 4 carbon atoms, EO is an oxyethylene group, l and m Are the average added mole numbers of oxyalkylene groups having 3 to 4 carbon atoms and oxyethylene groups, 1 ≦ l ≦ 50, 1 ≦ m ≦ 50, and the weight ratio of AO to EO (AO / EO) is 1. AO and EO may be added randomly or in a block form, BO is an oxyalkylene group having 4 carbon atoms, n is the average number of moles added, and 5 < n ≦ 30.)   A cosmetic base comprising an alkylene oxide derivative according to claim 1, wherein AO and EO are added in a random manner.   A cosmetic comprising the cosmetic base according to claim 1 or 2.   A cosmetic comprising 0.01 to 50% by weight of the cosmetic base according to claim 1 or 2 and 0.1 to 80% by weight of an oily component.   The cosmetic according to claim 4, further comprising 0.01 to 30% by weight of a humectant.