JP2006104073A - Composition for sedation - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a sedative composition excellent in an activity of mental sedation. <P>SOLUTION: This sedative composition is prepared by using a steam distillate obtained by the steam distillation of lavender, which is excellent in the activity of mental sedation or sound sleep-inducing effect. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a sedative composition. More specifically, the present invention relates to a sedative composition having a sedative effect.

  In recent years, aromatherapy using essential oil components derived from various plants has attracted attention as a means for reducing the mental adverse effects caused by stress and the like and calming the mind. In particular, it has been found that the essential oil component of lavender has an effect of calming the mind and an effect of inducing sleep (for example, see Patent Document 1), and the essential oil component of lavender is a fragrance for the purpose of calming the spirit. It is used a lot.

  However, in recent years, as aromatherapy has been in the limelight, there is a demand for aroma components that have a more excellent sedative effect, and conventional essential oil components that are known to have a sedative effect cannot satisfy consumer demand. Yes. Moreover, until now, most of the fragrance components having a sedative effect are essential oil components, and little is known about water-soluble fragrance components that exhibit an excellent sedative effect.

By the way, when producing essential oil by steam distillation of lavender, the water-soluble fraction (steam-distilled water) produced as an accessory component is not known for its properties and effective usage, and soothes and sleeps. Is not known at all.
JP-A-11-343497

  Then, the objective of this invention is providing the composition for sedation which is excellent in the effect | action which sedates a mind.

  As a result of diligent studies to solve the above problems, the present inventors have found that steam-distilled water obtained by steam-distilling lavender is excellent in the action of calming the mind and inducing sleep. It was. The present invention has been developed through further studies based on such findings.

That is, the present invention provides the following inventions:
Item 1. A soothing composition comprising steam distilled water of lavender.
Item 2. Item 2. The sedative composition according to Item 1, wherein the steam-distilled water of lavender is obtained from the above-ground part or whole grass of lavender.
Item 3. Item 3. The sedative composition according to Item 1 or 2, wherein the lavender is Okamurasaki or an improved variety thereof.

  The present invention is described in detail below. In the present invention, the “sedative composition” is used for calming, relaxing, or inducing a sleep of a person or an animal.

  The sedative composition of the present invention is characterized by containing lavender steam distilled water.

Lavender is a plant species belonging to Labiatae , Lavandula , genuine lavender (scientific name; Lavandula angustifolia, heterogeneous name; L. officinalis, L. vera), spike lavender (scientific name; L. spica, Other names: L. latifolia), Stoekas (scientific name: L. stoechas), Labandin (scientific name: L. hybrida), etc. In the present invention, the type of lavender to be used is not particularly limited, but an authentic lavender can be mentioned as a preferable one. Particularly preferred examples include various varieties such as Okamurasaki, Hanamoiwa, dark purple early bloom, and Yodei, and most preferred are Okamurasaki or improved varieties thereof, particularly those produced in Hokkaido, Japan. The lavender may be a wild species or a cultivated species.

  As raw materials for lavender steam distilled water, lavender flowers, spikes, fruits, pericarps, stems, leaves, branches, branches and leaves, stems, bark, rhizomes, root barks, seeds are used alone or in combination. Alternatively, whole lavender plants may be used. The raw material of lavender steam distilled water is preferably the above-ground part (whole grass excluding roots) or whole grass. By using these, the sedative effect and the sleep inducing effect are remarkably exhibited.

  Lavender steam distilled water is obtained by performing steam distillation using 0.6 to 2 parts by weight, preferably 0.8 to 1 part by weight of water with respect to 1 part by weight of lavender, and collecting the aqueous phase of the collected distillate. It is prepared by recovering. The method for steam distillation is not particularly limited, but a pressurized steam distillation method is preferable.

  The sedative composition of the present invention may be composed only of lavender steam distilled water, but contains other components such as a carrier, a substrate or an additive depending on the form of use. Also good. The blending ratio of lavender steam-distilled water in the sedation composition of the present invention varies depending on the use form of the composition, expected effects, etc., and cannot be uniformly defined. The ratio which the lavender steam distilled water becomes 0.01 to 100 weight% with respect to a weight, Preferably it is 1 to 100 weight%, More preferably, it is 10 to 100 weight%.

  The shape of the sedative composition of the present invention may be any shape such as liquid, gel, solid, gel, paste, and sheet, and may be appropriately set according to the use form and purpose of use. That's fine.

  The sedative composition of the present invention can also be used by supporting it on a nonwoven fabric, sheet, film or the like as a carrier (holding body). Thus, the carrier material for carrying the sedative composition of the present invention is not particularly limited, and examples thereof include natural fibers such as pulp, cotton, wool, hemp and silk; polypropylene, polyethylene, polyamide, polyethylene terephthalate, and polybutylene. Synthetic fibers such as terephthalate, polysulfone, rayon, methacrylic acid resin, and glass fiber; and porous materials such as zeolite, talc, white carbon, diatomaceous earth, lime, silica gel, and activated carbon.

  The sedation composition of the present invention is not limited in its form as long as the lavender steam distilled water is volatilized and the fragrance is exhibited.

  As an example of the form of the composition for sedation of this invention, what is used in the aspect which vaporizes or volatilizes the lavender steam distilled water to indoor space is mentioned. Specific examples of such a soothing composition include products such as aroma candles and indoor fragrances. By using the composition for sedation of this form, the steam distilled water of lavender is transpired into the space, and the effect of calming the mind can be given to the person or pet existing in the space.

  Other forms of the sedative composition of the present invention include cosmetic forms such as lotion, emulsion, cream, ointment, lotion, oil, pack, foundation, lipstick, blusher, and bath preparation. Thus, by using the sedative composition of the present invention as a cosmetic, a sedative effect of the mind can be obtained through the use of the cosmetic. Further, the sedative composition of the present invention may be in the form of an external preparation for skin (external medicine or quasi drug).

  In addition to the above, the sedative composition of the present invention includes, for example, bedding such as bedding and pillows; clothing; curtains; doors; screen doors; Are used in the form of spraying or coating. By using the sedative composition of this form, the components of the lavender steam-distilled water are volatilized from the daily necessities to which the sedative composition is adhered, thereby producing an excellent sedative effect. Examples of such forms include spray preparations, aerosol preparations, liquid, gel or cream preparations, and those obtained by impregnating them with a nonwoven fabric or the like.

  The composition for sedation of the present invention uses lavender steam distilled water, which is a natural ingredient, and has high safety, so that it not only volatilizes in the space, but is applied or sprayed to daily necessities. Can be applied directly to human skin as a cosmetic.

  Further, the sedative composition of the present invention has an excellent sedative effect in addition to an excellent sedative effect, so it is also useful as a composition for inducing sleep or a sedative sleep component, and insomnia It is preferably used for people who have poor sleep.

  In particular, the steam-distilled water obtained from the above-ground part of the lavender or the whole plant has a particularly prominent sleep / sedation effect, and the sedative composition containing the steam-distilled water is extremely useful.

EXAMPLES Hereinafter, although an Example is given and this invention is demonstrated, this invention is not limited to these Examples.
Example 1 Preparation of steam-distilled water of lavender A steam-distillation of about 50 kg of water was performed on 60 kg of the above-ground part (whole plant excluding roots) of lavender (Okamurasaki). A distillate containing 36 kg was made. The aqueous phase was recovered from the distillate to obtain lavender steam distilled water.

Test example 1
The paper (40 mm long, 40 mm wide, 5 mm thick) impregnated with about 4 g of lavender steam distilled water obtained in Example 1 was placed on the monitor of a desktop personal computer at the office desk. Named subjects (subjects 1 to 3) performed a task of inputting simple numerical data into a personal computer for 15 minutes, and evaluated the accuracy of the task (input correct answer rate) and the worker's fatigue. As a comparison, one 30-year-old subject (subject 4) used water instead of lavender steam distilled water to perform the same personal computer input work as above, and the accuracy of the work ( Input accuracy rate) and worker fatigue were evaluated. At the same time the day before the test, water was used instead of lavender steam distilled water, and the subjects 1 to 4 performed the same personal computer input operation as described above, and the result was used as a control. Specifically, the evaluation was performed according to the following criteria.
<Evaluation criteria>
Work accuracy A: The input accuracy rate was clearly improved compared to the previous day B: The input accuracy rate was not significantly different from the previous day C: The input accuracy rate was clearly reduced compared to the previous day
Fatigue A: Fatigue during work and after work is less than the previous day B: Fatigue after work and after work is the same as the previous day C: Fatigue during work and after work compared to the previous day The results obtained are shown in Table 1. As a result, in an environment where the sedative composition of the present invention is volatilized, it was confirmed that an accurate operation was performed and there was little fatigue after the operation. From the above results, it was suggested that the sedative composition of the present invention has an excellent sedative effect of the spirit, and a relaxing effect can be obtained in an environment where the composition is volatilized.

Test example 2
Three subjects were randomly selected from adults with poor sleep or insomnia. 350 ml of the lavender steam distilled water obtained in Example 1 is put in a known volatile liquid volatilization container, this is placed at the bedside, and the above three subjects sleep at this state. The effect of the composition on sleep was evaluated. In addition, evaluation evaluated (1) falling asleep, (2) depth of sleep, (3) awakening during sleep, and (4) the state of awakening according to the following evaluation criteria.
<Evaluation criteria>
A: Good compared to usual B: No change compared to usual C: Bad compared to usual The results obtained are shown in Table 2. As a result, it was confirmed that the sedative composition of the present invention has an excellent sleep promoting effect and sleep inducing effect.

Test example 3
Three subjects were randomly selected from adults with poor sleep or insomnia. 50 ml of the lavender steam-distilled water obtained in Example 1 was added to a bathtub filled with about 200 L of hot water. The three subjects soaked in this bathtub for about 5 minutes and then went to bed within 30 minutes, and the sleepiness at that time was evaluated according to the following evaluation criteria.
<Evaluation criteria>
A: Good compared to usual B: No change compared to usual C: Bad compared to usual Table 3 shows the obtained results. As a result, even when the sedative composition of the present invention was used as a bath agent, it was confirmed that, as with the result of Test Example 2, sleep was improved and an excellent sleep promoting effect and sleep inducing effect were obtained. It was.

Reference Example Composition Analysis The components of the lavender steam distilled water and lavender essential oil obtained in Example 1 were analyzed by gas chromatography. As the lavender essential oil to be analyzed, the oil phase recovered from the distillate produced by steam distillation in Example 1 was used. For analysis, 47.5 g of lavender steam distilled water obtained in Example 1 was mixed with 2.5 g of hexane, and the lavender essential oil diluted with methanol to 1% by weight was used as samples. The analysis conditions are as follows.
<Analysis conditions>
Gas chromatograph
HP 6890 series made by Hewlett Packard
Column DB-5MS
Length 30m
Inner diameter 0.25mm
Film thickness 0.25μm
Oven initial temperature 50 ° C 7 minutes Temperature rise to 100 ° C at 5 ° C per minute Temperature rise to 250 ° C at 20 ° C per minute 250 ° C constant temperature 10.5 minutes Total analysis time 45 minutes
Inlet temperature 250 ℃
Split ratio 10: 1
Total flow rate 9.8ml / min Carrier gas Ultra high purity helium
Sample injection volume 2 μl
Detector FID (hydrogen flame ionization) detector.

  A chromatograph obtained for lavender steam distilled water is shown in FIG. 1, and a chromatograph obtained for lavender essential oil is shown in FIG. The peak patterns are different between FIG. 1 and FIG. 2, and it was confirmed that lavender steam distilled water and lavender essential oil have different compositions.

It is a figure which shows the result (chromatograph) which analyzed the steam distilled water of the lavender obtained in Example 1 by gas chromatography. It is a figure which shows the result (chromatograph) which analyzed the lavender essential oil by the gas chromatography.

Claims (3)

A soothing composition comprising steam distilled water of lavender. The composition for sedation according to claim 1, wherein the lavender steam distilled water is obtained from the above-ground part or whole grass of lavender. The sedative composition according to claim 1 or 2, wherein the lavender is okamurasaki or an improved variety thereof.

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