JP2014005403A - Perfume composition and cosmetics - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a perfume composition that activates a human brain cell, increases concentration, enhances work efficiency, and creates an environment with no stress.SOLUTION: A perfume composition contains Sciadopitys verticillata essential oil, and essential oil selected from a group consisting of Alpinia speciosa essential oil, Mentha canadensis var. piperascens essential oil, Perilla frutescens essential oil, and mixture of two or more of them.

Description

  The present invention relates to a novel fragrance composition containing a fragrance component. Furthermore, it is related with the cosmetics containing the said fragrance | flavor composition.

  In recent years, it has been reported that aroma components have various effects on human physiology and psychological state through olfaction. This physiological and psychological action includes, for example, an effect of improving relaxation / sedation, an effect of improving exhilaration, promoting sleep (arousal), stress relief, improving responsiveness, or suppressing effects, etc. The effect is verified by various methods as a fragrance material or a blended fragrance. Especially in modern society where there are many factors that cause transient mental stress, diseases caused by stress are increasing. Therefore, various methods for relieving stress have been developed. In particular, there is a high interest in aroma therapy using aroma (aromatherapy), which is popular as a means for creating a comfortable environment in, for example, stressful workplaces and public places. Also in the cosmetics industry, fragrance effects in cosmetics have been demonstrated in consideration of psychological factors including stress reflecting such a tendency. The influence of fragrance on work efficiency is also one of the effects brought about by fragrance, and there is a demand for a fragrance composition having an effect of improving work efficiency in the workplace or school.

  Known methods for measuring the effects of fragrance on work efficiency include the Kraepelin test and the Uchida-Kraepelin test, and these methods can be used to smell the scent of the component R-(-)-linalool. Therefore, it has been reported that the amount of work increases and the error rate decreases (Non-Patent Document 1). Moreover, when the subject was given a scent of jasmine or α-pinene, it was reported that the work answer correction rate in the Kraepelin test was significantly reduced compared to the control (Non-patent Document 2). Moreover, it has been reported that the fragrance | flavor composition containing patchouli oil can improve the efficiency of mental work (patent document 1).

JP 2006-312691 JP 2001-233756 A

AROMA RESEARCH No.15 (Vol.4 / No.3 2003) p.68-75 Japanese Journal of Taste and Smell, Vol. 23, pp. 55-38, 1989

  An object of the present invention is to provide a fragrance composition that can activate human brain cells to increase concentration, improve work efficiency, and produce a stress-free field. Furthermore, this invention aims at providing the cosmetics which use the said fragrance | flavor composition. The cosmetic of the present invention works directly on the human body by, for example, applying to the skin or inhaling a fragrance component prior to performing a task requiring concentration, and activates brain cells by the fragrance component. It can be awakened, and the work efficiency of human beings can be remarkably improved.

  The present inventors have found that plant essential oil components obtained by the steam distillation method from leaves, trees, branches, flowers, etc. of Koyamaki (Takano moth) can activate brain cells in the body and improve work efficiency. The present invention has been completed.

The present invention provides the following.
[1] A fragrance composition containing Kouyamaki essential oil and moon peach essential oil, Japanese mint essential oil, perilla essential oil, and an essential oil selected from the group consisting of two or more thereof.
[2] The fragrance composition according to the above [1], wherein the content of Kouyamaki essential oil is 0.01 to 0.1% by weight.
[3] The content ratio of Kouyamaki essential oil and essential oil selected from the group consisting of moon peach essential oil, Japanese mint essential oil, perilla essential oil, and a mixture of two or more thereof is 0.1: 1 to 0.001: 1, 1].
[4] A cosmetic comprising the fragrance composition according to any one of [1] to [3] above.
[5] An aroma fragrance containing the fragrance composition according to any one of [1] to [3] above.

  The fragrance composition of the present invention has an effect of activating and awakening human brain cells, and can improve human working efficiency.

The fragrance composition of the present invention contains Kouyamaki essential oil and essential oil selected from the group consisting of moon peach essential oil, Japanese mint essential oil, perilla essential oil, and a mixture of two or more thereof.
Kouyamaki (Takano mushroom) is an evergreen conifer that is an endemic species of the Japanese pine family Kouyamaki. Kouyamaki is often used as a flower for the Buddha. Kouyamaki essential oil is obtained by extraction by steam distillation from undersold leaves and cut leaves and branches, and is known to give off a refreshing and cored fragrance.

  Moon peach is a perennial plant belonging to the genus Glycoaceae and is mainly used as a houseplant. Moon peach essential oil is obtained by extraction from moon peach leaves by a steam distillation method, and is known to give off a sweet fragrance having an insect repellent effect and the like.

  Japanese mint (Japanese thin load) is a perennial plant belonging to the genus Labiatae. Japanese peppermint essential oil (peppermint oil) can be obtained by extraction by a steam distillation method, and is used as a fragrance such as confectionery and strawberries in addition to pharmaceutical use.

  Perilla (Shiso) includes all of Aojiso, Akajiso, chimmentiso used as a traditional Chinese medicine, and the like, which are used as it is in plants of the family Lamiaceae. Perilla essential oil is obtained by extraction from the stems and leaves of these Labiatae plants by the steam distillation method, and is known as an essential oil having effects such as sterilization, disinfection, and appetite enhancement.

  The fragrance composition of the present invention includes a blended oil obtained by mixing these essential oils. The fragrance composition of the present invention preferably contains 0.001 to 1% by weight, preferably 0.01 to 0.1% by weight, of Kouyamaki essential oil. If the content of Kouyamaki essential oil is too small, the effect of activating human brain cells is weak, and if the content of Kouyamaki essential oil is too high, the scent peculiar to trees is too strong, and the likes and dislikes by people can increase.

  For example, when blending so that the content ratio of Kouyamaki essential oil and the essential oil selected from the group consisting of moon peach essential oil, Japanese mint essential oil, perilla essential oil and a mixture of two or more thereof is 0.1: 1 to 0.001: 1, It becomes a blended oil having a balanced fragrance without losing the brain cell activation effect of Kouyamaki essential oil. The blend ratio of each essential oil can be changed as appropriate, such as increasing the content of moon peach essential oil when a sweet aroma is preferred, and increasing Japanese mint essential oil when a refreshing and refreshing aroma is preferred.

  The fragrance composition of the present invention can be used as it is for an aromatic bath or the like. Moreover, the fragrance composition of the present invention can be impregnated into a base material such as paper, a porous material, or a resin material by coating or the like to produce various articles that emit aroma. Furthermore, the fragrance composition of the present invention can be mixed with liquid oil, solid oil, water or the like and used as various cosmetics. The perfume composition of the present invention is particularly compatible with the Tokai squalane extract disclosed in JP-A-2001-233756 (Patent Document 2), and by mixing with this, an oil pack agent or cosmetic oil is obtained. Can be used.

  Here, Toki is a perennial plant belonging to the genus Cericidae and is particularly famous for its use as a herbal medicine. When the roots and stems of Toki are extracted in a high temperature region (for example, 90 ° C. or more) using an oily solvent composed of one or more of hydrocarbons, fats and waxes, the Toki extract can be obtained. At this time, a squalane extract using squalane as an oily solvent is used. Squalane is obtained by hydrogenating and stabilizing squalene, which is the main component of liver (liver oil) of deep sea bream. It is known that squalene is also contained in olive oil and sebum. In addition to those obtained from nature, squalane can be obtained by chemical synthesis and can be used in the cosmetics of the present invention. However, when used as an oil pack agent or cosmetic oil, It is more preferable to use the obtained squalane. The cosmetics of the present invention have effects such as improvement of skin firmness, improvement of skin roughness, reduction of skin wrinkles or reduction of acne, etc. In addition to the effects of the perfume composition of the present invention mixed, The brain cells are activated and awakened to improve work efficiency.

FIG. 1 is a conceptual diagram illustrating an apparatus for testing the effectiveness of the fragrance composition of the present invention. FIG. 2 is a drawing for explaining the flow of the effectiveness test of the fragrance composition of the present invention. FIG. 3a is a graph showing the time transition of the correct answer rate in the vigilance test. FIG. 3b is a graph showing the time transition of the reaction time in the vigilance test. FIG. 4 is a diagram showing the subjective evaluation of Kouyamaki essential oil. FIG. 5a is a graph showing the time variation of the average heart rate. FIG. 5b is a graph showing the temporal variation of the heartbeat (high frequency component). FIG. 5c is a graph showing the time variation of the ratio between the high frequency component and the low frequency component of the heartbeat. FIG. 6 a is a graph showing the time transition of the intensity of the observed α-wave. The left graph shows the results for the C3 position electrode, and the right graph shows the results for the C4 position electrode. FIG. 6 a is a graph showing the time transition of the intensity of the observed β wave. The left graph shows the results for the C3 position electrode, and the right graph shows the results for the C4 position electrode. FIG. 7 is a graph showing the salivary amylase activity of a subject before and after presentation of Kouyama essential oil-containing air. FIG. 8 is a graph showing changes in the pulse rate of the subject before and after presentation of Kouyamaki essential oil-containing air.

  The fragrance composition of the present invention is a fragrance bath that is diffused in the air by means of heating or ultrasonic vibration using a known material such as a porous material such as an unglazed pot or a ceramic dish or an aroma diffuser. Can be used. The fragrance composition of the present invention can be added to oils such as wax and wax and hardened to a specific shape and used as an aroma candle or butter. The fragrance composition of the present invention can be used in the form of indoor fragrances, aerosol fragrances, incense sticks, incense sticks, various textile products such as clothes, carpets, curtains, towels, handkerchiefs, wallpaper, wrapping paper, tissues, It is also possible to very suitably carry out soaking in various paper products such as origami and notebook.

  When the fragrance composition of the present invention is diffused into the environment using the above-mentioned means, various trace components of the blend oil are taken into the human body from the olfactory sense and exert effects such as activation of brain cells. Alternatively, by diffusing the perfume composition of the present invention into the environment, the effects of the moon peach essential oil, Japanese mint essential oil, and perilla essential oil, which are contained together with Kouyamaki essential oil, such as bactericidal / disinfecting action, appetite promoting action In addition to exerting an effect, it also helps to produce a refreshing environment.

  Furthermore, the fragrance composition of the present invention can be mixed with liquid oil, solid oil, water or the like and used as various cosmetics. For example, an appropriate base material (for example, oil, powder or water) is selected according to the use mode such as oil pack agent, cosmetic oil, lotion, emulsion, cream, gel, perfume, soap, bath agent, etc. If necessary, suitable cosmetics can be produced by adding additives usually used in the production of cosmetics such as emulsifiers, humectants, anti-inflammatory agents, colorants, and fragrances.

[Efficacy test method]
A method for analyzing the influence on human work efficiency and physiological / psychological response when the fragrance composition of the present invention is exposed to diffused air will be described below. Specifically, air containing a fragrance composition is presented to the subject, color vision discrimination work (vigilance test) is performed, and simultaneously the subject's electrocardiogram and electroencephalogram are recorded. On the other hand, the amylase activity in the saliva of the subject before and after the presentation of the air containing the fragrance composition was measured. In order to perform a subjective evaluation of the subject regarding the air containing the fragrance composition, a questionnaire was conducted at the initial stage of presentation and after presentation of the air containing the fragrance composition.

1. Presentation of Kouyamaki Essential Oil-Containing Air Presentation of Kouyamaki essential oil-containing air to subjects was performed for 45 minutes. The amount of Kouyamaki essential oil was two conditions of high or low concentration set from the preliminary test, and diluted with squalane. The high concentration referred to here was a concentration that could clearly recognize the fragrance and was not unpleasant as a result of sensory evaluation of 5 to 6 persons, and was 212.8 ± 0.6 μg / 45 L (air) in this test. On the other hand, the low concentration was a concentration at which the above-mentioned evaluator could slightly recognize the scent, and in this test was 35.6 ± 0.8 μg / 45 L (air). Air containing Kouyamaki essential oil was presented at a flow rate of 1.0 L / min to subjects in a soundproof room (Avitex, manufactured by Yamaha).

2. Component analysis of presentation air by GC-MS Quantitative analysis of essential oil components in presentation air uses a gas chromatograph-mass spectrometer (GC-MS, manufactured by Shimadzu Corporation) and a DB-5 column (manufactured by Agilent Technologies). I went wearing it. The air presented to the subject was collected in a Tedlar bag, adsorbed with an adsorption tube (ORBO100, manufactured by Spelco), eluted with acetone, and analyzed by GC-MS.

3. The subject test was conducted in accordance with Kyushu University regulations and the Declaration of Helsinki. The subjects were 7 or 8 healthy male college students who had confirmed beforehand that there were no problems with olfaction or physical and mental health, and that they had no medication or smoking habits.

4). Color vision discrimination (Vigilance test)
A vigilance test is a test for measuring the degree of maintenance of attention to visual stimuli. On the monitor screen set 100cm horizontally from the subject's eye position, the numbers 0 to 9 are projected for 0.04 seconds (one number per second), and only when the mouse is 0, the correct answer is obtained by clicking the mouse. The correct answer rate was recorded. The working time was 30 minutes, and mosaic-like random dot noise was added to the displayed numbers in order to adjust the difficulty of the test.

5. Recording of electrocardiogram and electroencephalogram The electrocardiogram and electroencephalogram data were analyzed using an electroencephalogram monitor (MWM-01, manufactured by GMS) in real time using an analysis system (MemCalc Ver. 2.5, manufactured by GMS). The electrocardiogram was derived from CM5.

  The index of heart rate variability was the change over time of the center point derived from the R wave interval (RR interval). Moreover, 0.04-0.15Hz is defined as a low frequency component (Low Frequency, LF), 0.15-0.4Hz is defined as (High Frequency, HF), HF is used as an index of parasympathetic nerve activity, and LF / HF ratio is used as the sympathetic nerve activity. It was used as an index.

The electroencephalogram was measured from the C3 and C4 positions based on the International Electroencephalographic Society Standard Electrode Placement Method, and analyzed focusing on theta waves (4.0 to 8.0 Hz) and alpha waves (8.0 to 13.0 Hz).
6). Subjective evaluation Subjects were asked to respond to a questionnaire at the beginning and after presentation of air containing Kouyamaki essential oil. The following eight evaluation criteria (synonyms) were set, and subjective evaluation was analyzed using a visual analog scale: unpleasant-pleasant; blurred-clear, heavy-light, artificial-natural Dangerous-safe; not calm-calm; not clean-clean; odorless-intense.

7). Measurement of amylase activity in saliva The saliva of a subject was collected using a disposable test strip. The timing of saliva collection was before the start of the test and after the end of the test. The collected saliva was measured using COCORO METER (manufactured by Nipro) for the amylase activity contained.

  A specific apparatus for testing the effectiveness of the perfume composition of the present invention is shown in FIG. An approximate flow of the effectiveness test is shown in FIG.

Effect of Koyamaki Essential Oil on Human Work Efficiency Using the apparatus shown in FIG. 1, the effect of Koyamaki essential oil on the work efficiency of the subject was measured by the experimental method shown in FIG. The results of color vision discrimination work (Vigilance test) are shown in FIG. FIG. 3a shows the time course of the correct answer rate in the vigilance test. In the control, the group presented with a high concentration of Kouyamaki essential oil and the group presented with a low concentration of Kouyamaki essential oil, the correct answer rate decreases with time. FIG. 3b shows the time course of the reaction time in the vigilance test. In any group, the reaction time increases with the passage of time, but the increase in the reaction time is significantly small in the group presented with a low concentration of Kouyama essential oil.

Subjective evaluation of Kouyamaki essential oil presentation air The questionnaire responses of subjects were analyzed for Kouyamaki essential oil-containing air. The results are shown in FIG. The group presented with low-concentration Kouyamaki essential oil-containing air evaluated the Kouyamaki essential oil-containing air as “comfortable”, “light”, “natural”, “safe”, “settled”, “clean”.

ECG measurement Since the heart plays a role in maintaining physical function through blood circulation, it is possible to estimate whether the person is relaxed or in tension by measuring the ECG and analyzing the heart rate. it can. Further, since heart rate fluctuations are affected by the balance of autonomic nerve activity, the HF component value and LF / HF value obtained from the electrocardiogram can be used as indices of parasympathetic nerve activity and sympathetic nerve activity, respectively. The results of electrocardiogram analysis are shown in FIGS. 5a, 5b and 5c. FIG. 5a shows the time variation of the average heart rate, and the tendency of increasing heart rate is seen in the air containing Kojiyama essential oil. FIG. 5c shows the time variation of the ratio between the high-frequency component and the low-frequency component of the heartbeat, and the group presented with air containing a low concentration of Kouyamaki essential oil has increased sympathetic nerve activity in the second half of the test. The tendency to be seen can be seen.

EEG measurement The nerves in the brain are constantly active and transmitting information. The brain waves indicating the state of cranial nerve activity are named α waves, β waves, θ waves, and δ waves for each frequency band.

  As shown in Table 1, it is possible to estimate the degree of human tension and concentration when each brain wave is observed. Therefore, the electroencephalogram of the group that presented the air containing Kouyamaki essential oil was measured. The results are shown in FIGS. 6a and 6b. FIG. 6 a shows the time transition of the intensity of the observed α-wave, and the group presenting Kouyama essential oil-containing air has a tendency that the α-wave is observed strongly, particularly in the C4 region. FIG. 6b shows the time transition of the intensity of the observed β wave. In particular, in the group presenting air containing Kouyamaki essential oil at a low concentration, the β wave is strongly observed. From this result, it is presumed that Kouyamaki essential oil can maintain the human brain in a certain tension state or arousal state.

Measurement of salivary amylase activity It is known that salivary amylase activity increases when sympathetic nerves are excited. Therefore, salivary amylase activity can be used as an index of human stress state. Therefore, in order to estimate the stress state of subjects presented with Kouyamaki essential oil-containing air, the salivary amylase activity of subjects before and after presentation of air was measured. The results are shown in FIG. There was a tendency for salivary amylase activity to increase in subjects presented with air containing Kouyamaki essential oil at low concentrations.

It is known that the pulse rate increases when the pulse measurement sympathetic nerve is excited. Therefore, the pulse rate can be used as an index of the human stress state. Therefore, in order to estimate the stress state of subjects presented with Kouyamaki essential oil-containing air, the pulse rate of subjects before and after presentation of air was measured. The results are shown in FIG. The pulse rate of subjects presented with air containing Kouyamaki essential oil remained higher than controls.

From the results of Examples 1 to 6, the following can be said for Kouyama essential oil:
Subject presented with Kouyamaki essential oil-containing air, delay of reaction time in vigilance test was suppressed. This effect was particularly remarkable when air containing a low concentration of Kouyamaki essential oil was presented. In addition, air containing Kouyamaki essential oil at a low concentration is highly evaluated as “natural”, “safe”, “settled”, and the like. Furthermore, from the results of electroencephalogram analysis, salivary amylase activity measurement, and pulse measurement, it can be said that the subject presented with Kouyama essential oil-containing air concentrates on the work while maintaining an appropriate tension state. Thus, it was found that Kouyamaki essential oil-containing air (particularly in the case of a low concentration) can maintain a comfortable working environment and improve human working efficiency.

Preparation of diffuser oil containing Kouyamaki essential oil Kouyamaki essential oil and moon peach essential oil were blended and stirred uniformly to prepare a diffuser blend oil. This oil had a refreshing fragrance.

Production of room fragrance (type 1) containing Kouyamaki essential oil A room fragrance (type 1) containing Kouyamaki essential oil and moon peach essential oil was produced. Table 3 shows the mixing ratio of each component. Ingredient A in the table was mixed and stirred uniformly. The component B was added here, and it stirred uniformly, and obtained the base. Ingredient C was soaked and allowed to stand for 24 hours, after which ingredient C was taken out and dried to obtain a room fragrance (type 1).

Production of Room Fragrance (Type 2) Containing Kouyamaki Essential Oil A room fragrance (type 2) containing Kouyamaki essential oil and moon peach essential oil was produced. Table 4 shows the mixing ratio of each component. Ingredient A in the table was mixed and stirred uniformly. The component B was added here and it stirred uniformly. Component C was added thereto and stirred uniformly to obtain a room fragrance (type 2).

Production of body butter containing Toki Squalane extract and Kouyamaki essential oil A body butter containing Toki Squalane extract and Kouyamaki essential oil obtained by the method described in Example 2 of JP-A-2001-233756 was produced. . Table 5 shows the mixing ratio of each component. First, component A was heated to 60 ° C. to make it uniform. Next, component B was added to be uniform, cooled and solidified to obtain body butter.

Preparation of a candy that contains Kouyamaki essential oil A candy that contains Kouyamaki essential oil and moon peach essential oil was prepared. Table 6 shows the mixing ratio of each component. First, component A was mixed and made uniform. Component B was then added and made uniform. The component C was added here, and it pressed and obtained the gauze.

Preparation of bathing agent containing Kouyamaki essential oil A bathing agent containing Kouyamaki essential oil and moon peach essential oil was prepared. Table 7 shows the blending ratio of each component. First, component A was mixed and made uniform. Component B was then added and made uniform. The component C was added here and the bath agent was obtained.

Preparation of Facial Mask (Pre-processed Product) Containing Kouyamaki Essential Oil A facial mask (pre-processed product) containing Kouyamaki essential oil and moon peach essential oil was prepared. Table 8 shows the mixing ratio of each component. First, component A was heated to 80 ° C. to make it uniform. Ingredient B was mixed and heated to 90 ° C. and added to ingredient A above. This was solubilized at 80 ° C. and then cooled to 35 ° C. Finally, component C was added and homogenized, and high pressure emulsification (220 MPa) was performed to obtain a facial mask (pretreatment product).

Preparation of facial mask containing Kouyamaki essential oil A facial mask containing Kouyamaki essential oil and moon peach essential oil was prepared. Table 9 shows the mixing ratio of each component. First, component A was heated to 80 ° C. to make it uniform. The component B was added here and solubilized. After cooling this to 40 ° C., component C was added to make it uniform. Finally, it was cooled to 35 ° C. to obtain a facial mask. Note that the facial mask (pre-processed product) of Example 13 is a primary processed product of the facial mask, and the facial mask of Example 14 is a facial mask product using the pre-processed product of Example 13. .

Preparation of cream containing Kouyamaki essential oil A cream containing Kouyamaki essential oil and moon peach essential oil was prepared. Table 10 shows the mixing ratio of each component. First, component A was heated to 80 ° C. and stirred to make it uniform. Separately, component B was mixed and heated to 90 ° C., and component A described above was added thereto to emulsify. This was cooled to obtain a cream.

Preparation of incense containing Kouyamaki essential oil An incense containing Kouyamaki essential oil and moon peach essential oil was prepared. Table 11 shows the blending ratio of each component. First, component A was mixed and made uniform. Component B was then added to make it uniform. The component C was added here, and it stirred uniformly, knead | mixed, shape | molded and obtained the incense stick.

Preparation of incense containing Kouyamaki essential oil Yaki incense containing Kouyamaki essential oil and moon peach essential oil was prepared. Table 12 shows the mixing ratio of each component. First, component A was mixed and made uniform. Subsequently, the component B previously mixed was added and made uniform. The component C was added here, and it stirred uniformly, and obtained incense.

Claims (5)

  A fragrance composition comprising Kouyamaki essential oil, and essential oil selected from the group consisting of moon peach essential oil, Japanese mint essential oil, perilla essential oil, and a mixture of two or more thereof.   The fragrance | flavor composition of Claim 1 whose content of Kouyamaki essential oil is 0.001-1 weight%.   The content ratio of Kouyamaki essential oil and essential oil selected from the group consisting of Tsuki Peach essential oil, Japanese mint essential oil, perilla essential oil, and a mixture of two or more thereof is 0.1: 1 to 0.001: 1. Perfume composition.   Cosmetics containing the fragrance composition according to any one of claims 1 to 3.   The aroma fragrance containing the fragrance | flavor composition of any one of Claims 1-3.