201212949 六、發明說明： 【發明所屬之技術領域】 本發明係關於-種抑制交感神經之活動的交感神經抑 制劑及使皮膚溫度下降的皮膚溫度下降劑。又，本發明係 關於種具有交感神經抑制效果或皮膚溫度下降效果的化 妝料、食品、及雜貨。 【先前技術】 現代社會中，為壓力導致自主神經之平衡破壞、自主 神經失調引起之症狀而煩惱的人正在增力”自主神經係由 交感神經與副交感神經兩種神經系統所構成，互相控制而 保持平衡。自主神財，緊張時或興奮時主㈣交感神經 1活動變得活躍’放鬆時主要係❹感神經之活動變得活 躍。然而，若由於壓力等而使該交感神經之亢進狀態持續， 則與副交感神經之平衡破壞，產生失眠、血流障礙、及焦 躁之狀態持續等各種症狀。 因此，正在進行藉由抑制交感神經之活動，而緩和如 上所述之狀態之交感神經抑制劑的開發（參照專利文獻1)。 另—方面，為因荷爾蒙之平衡破壞而引起的更年期障 礙而煩惱的人正在增加。更年期障礙患者多見之發熱之症 狀係由於皮膚之溫度上升而引起。作為緩和發熱之症狀之 方法，已知體質改善等。 專和文獻1.日本公開公報2004—067537A 【發明内容】 …、而，由於現代人常常置身於壓力狀態，故而希望開 201212949 發更優異之交感神經抑制劑。 又，近年來，一般認為，由於荷 〜呵象之平衡破壞而使 更年期障礙之患者於青年層中亦増加， 故而為更年期障礙 之症狀而煩惱的人口增加，從而希望 τ •開發緩和發熱之症狀 的皮膚溫度下降劑。 鑒於如上所述之情況，本發明之目的在於提供一種更 有效地抑制交感神經之活動的交感神經抑制劑及使皮膚溫 度下降的皮膚溫度下降劑。又，其目的在於提供一種具有 交感神經抑制效果或皮膚溫度下降效果的化妝料、食品、 及雜貨。 本發明之一態樣之交感神經抑制劑，由丨，8 _桉樹油 (1，8 - cineole )構成。 又，本發明之其他態樣之交感神經抑制劑，含有〇 〇〇 i 質量。/〇以上5 0質量％以下之1，8 —桉樹油。 進而，本發明之其他態樣之皮膚溫度下降劑，由丨，8 一 桉樹油構成。 進而，本發明之其他態樣之皮膚溫度下降劑，含有0_001 質量以上50質量。/。以下之1，8 —桉樹油。 進而’本發明之其他態樣之化妝料，含有上述交感神 經抑制劑或上述皮膚溫度下降劑。 進而’本發明之其他態樣之食品，含有上述交感神經 抑制劑或上述皮膚溫度下降劑。 進而’本發明之其他態樣之雜貨，其含有上述交威神 經抑制劑或上述皮膚溫度下降劑。 4 201212949 =桉樹油使交感神經之活動鎮靜化。因此，本發明 感神經抑制劑有效地抑制交感神經之活動。 ’8桉樹油使面頰及手指尖之皮膚溫度下降。因 此本發明之皮膚溫度下降劑有效地使皮膚溫度下降。 進而’本發明之化妝料、食品、及雜貨由於含有由M 一桉樹油構成的交感神經抑制劑或皮膚溫度下降劑，故而 具有交感神經抑制效果或皮膚溫度下降效果。 【實施方式】 本實施形態之交感神經抑制劑含有桉樹油作為有 效成分。藉由吸入該交感神經抑制劑所含有之桉樹油 :香氣而使交感神經之活動鎮靜化。因此，本實施形態之 父感神經抑制劑更有效地抑制交感神經之活動。 又，本實施形態之皮膚溫度下降劑含有M—桉樹油作 為有效成分。#自吸入該皮膚溫度下降劑所含有之以—按 樹油之香氣而使面頰及手指尖之皮膚溫度下降。因此，本 實施形態之皮膚溫度下降劑更有效地使皮膚溫度下降。 於本實施形態中，所謂「抑制交感神經之活動」係指 與未聞到本實施形態之交感神經抑制劑所含有之丨，8 一桉樹 油之香氣時的交感神經之活動相比，聞到本實施形態之交 感神經抑制劑所含有之1，8 —桉樹油之香氣時的交感神經之 活動更鎮靜化。 又，於本實施形態中，所謂「皮膚溫度下降」，係指與 未聞到本實施形態之皮膚溫度下降劑所含有之1，8 _桉樹油 之香氣時的皮膚溫度相比，聞到本實施形態之皮膚溫度下 201212949 降劑所含有之1，8 _桉樹油之香氣時的皮膚溫度下降。 然而’本實施形態之交感神經抑制劑及皮膚溫度下降 劑並不限於聞到香氣之情形，藉由飲食於體内吸收之情 形’或自皮膚吸收之情形時亦實現交感神經抑制效果及皮 膚溫度下降效果。 以下’對本貫施形態之交感神經抑制劑及皮膚溫度下 降劑加以詳細說明。 (關於1，8 —按樹油） 1，8 —桉樹油係具有樟腦 於天然精油中之成分，尤其 的葉等成分。1，8 —桉樹油係 等直接或乾燥後切割成適當 得的萃取物。又，亦可使用 德。萃取方法並無特別限定 蒸顧法等蒸餾法’有機溶劑 常之精油之萃取方法，尤佳 1，8 —桉樹油由於可藉由公知 亦可使用市售之合成品。 般香氣的化合物，為廣泛存在 是較多地包含於桉樹或月桂樹 包含於自將桉樹及月桂樹之葉 大小或經粉碎加工者等萃取所 將該萃取物分離純化所得之分 ’可使用水蒸氣蒸餾法、熱水 萃取法、油脂吸附萃取法等通 為使用水蒸氣蒸餾法。再者， 之合成方法而合成’故而例如 1，8 一桉樹油係由下述化學式化1所表示 [化 1] ’、201212949 6. DISCLOSURE OF THE INVENTION: TECHNICAL FIELD The present invention relates to a sympathetic inhibitor for inhibiting the activity of sympathetic nerves and a skin temperature lowering agent for lowering skin temperature. Further, the present invention relates to a cosmetic, food, and miscellaneous product having a sympathetic suppression effect or a skin temperature lowering effect. [Prior Art] In modern society, people who are troubled by the stress caused by the balance of autonomic nerves and autonomic dysfunction are increasing. "The autonomic nervous system is composed of two nervous systems, the sympathetic nerve and the parasympathetic nerve, and is controlled by each other. Keeping balance. Self-reliance, when you are nervous or excited, the main (4) sympathetic activity becomes active. 'The activity of the main sensory nerve becomes active when you relax. However, if the hyperactivity of the sympathetic nerve continues due to stress, etc. Then, the balance with the parasympathetic nerve is destroyed, and various symptoms such as insomnia, blood flow disorder, and eschar state continue to occur. Therefore, sympathetic inhibitors which are mitigating the state as described above are being suppressed by inhibiting the activity of the sympathetic nerve. Development (see Patent Document 1). On the other hand, people who are worried about menopausal disorders caused by the balance of hormone damage are increasing. The symptoms of fever in menopausal disorders are caused by the temperature rise of the skin. The method of fever symptoms, known physical improvement, etc. Special and literature 1. Japan [J] No. 2004-067537A [Summary of the Invention] ..., and, because modern people are often in a state of stress, they hope to open a more excellent sympathetic inhibitor in 201212949. In addition, in recent years, it is generally believed that due to the balance of the lotus A patient who has been devastated and causes menopausal disorders is also added to the youth level, so that the number of people who are troubled by the symptoms of menopausal disorders increases, and it is desired to develop a skin temperature lowering agent that alleviates the symptoms of fever. In view of the above, the present invention It is an object of the invention to provide a sympathetic nerve inhibitor which more effectively inhibits the activity of sympathetic nerves and a skin temperature lowering agent which lowers the skin temperature. Further, it is an object of the invention to provide a cosmetic having a sympathetic nerve suppression effect or a skin temperature lowering effect, Food, and miscellaneous goods. A sympathetic nerve inhibitor according to one aspect of the present invention is composed of sputum, 8 _ oleole oil. Further, other aspects of the sympathetic inhibitor of the present invention contain bismuth. 〇i mass. / 〇 above 50% by mass of 1,8 - eucalyptus oil. Further, the present invention The skin temperature lowering agent of the aspect is composed of 丨, 8 eucalyptus oil. Further, the skin temperature lowering agent of the other aspect of the invention contains 50 mass of 0_001 mass or more, and the following 1,8 - eucalyptus oil. Further, the cosmetic of the other aspect of the present invention comprises the sympathetic inhibitor or the skin temperature lowering agent. Further, the food of the aspect of the present invention contains the sympathetic inhibitor or the skin temperature lowering agent. A groceries according to another aspect of the present invention, which comprises the above-mentioned contraindication nerve inhibitor or the above-mentioned skin temperature lowering agent. 4 201212949 = Eucalyptus oil calms the activity of the sympathetic nerve. Therefore, the sensory nerve inhibitor of the present invention effectively inhibits sympathetic Nerve activity. '8 Eucalyptus oil reduces the skin temperature of the cheeks and fingertips. Therefore, the skin temperature lowering agent of the present invention effectively lowers the skin temperature. Further, the cosmetic, the food, and the miscellaneous product of the present invention have a sympathetic nerve suppressing effect or a skin temperature lowering effect because they contain a sympathetic inhibitor or a skin temperature reducing agent composed of M-eucalyptus oil. [Embodiment] The sympathetic inhibitor of the present embodiment contains eucalyptus oil as an active ingredient. The activity of the sympathetic nerves is calmed by inhaling the eucalyptus oil contained in the sympathetic inhibitor: aroma. Therefore, the paternal nerve inhibitor of the present embodiment suppresses the activity of the sympathetic nerve more effectively. Further, the skin temperature lowering agent of the present embodiment contains M-eucalyptus oil as an active ingredient. #自抽 The skin temperature-decreasing agent contains - according to the aroma of the tree oil, the skin temperature of the cheeks and the tip of the finger is lowered. Therefore, the skin temperature lowering agent of the present embodiment more effectively lowers the skin temperature. In the present embodiment, the term "inhibition of sympathetic nerve activity" means that the sympathetic nerve activity of the sympathetic nerve inhibitor of the present embodiment is not detected, and the sympathetic nerve activity of the eucalyptus oil of the eighth eucalyptus oil is smelled. The activity of the sympathetic nerves in the aroma of 1,8-eucalyptus oil contained in the sympathetic inhibitor of the present embodiment is more calm. In the present embodiment, "the skin temperature is lowered" means that the skin temperature is lower than the skin temperature when the aroma of the 1,8 _ eucalyptus oil contained in the skin temperature lowering agent of the present embodiment is not detected. The skin temperature of the 1,8 _ eucalyptus oil contained in the 201212949 reducing agent at the skin temperature of the embodiment is lowered. However, the sympathetic inhibitor and skin temperature reducing agent of the present embodiment are not limited to the case where the aroma is smelled, and the sympathetic nerve suppressing effect and the skin temperature are also achieved by the case of eating in the body or in the case of absorption from the skin. Decrease effect. The following is a detailed description of the sympathetic inhibitor and the skin temperature lowering agent in the present embodiment. (About 1,8 - according to tree oil) 1,8 - Eucalyptus oil has ingredients such as camphor in natural essential oils, especially leaves and other ingredients. 1,8 — Eucalyptus oil is directly or dried and cut into suitable extracts. Also, you can use German. The extraction method is not particularly limited. Distillation method such as steam distillation method. Organic solvent The extraction method of the essential oil is particularly preferred. 1,8 - Eucalyptus oil can also be used as a commercially available synthetic product. A compound with a wide aroma, which is widely contained in eucalyptus or laurel, is obtained by extracting and purifying the extract from the leaves of eucalyptus and laurel, or by extraction with a pulverizer, etc. The method of steam distillation is used for the method, the hot water extraction method, the oil adsorption extraction method, and the like. Further, the synthesis method is synthesized. Thus, for example, 1,8 an eucalyptus oil is represented by the following chemical formula 1 [, 1]
6 201212949 再者，已知桉树油具有抗過敏活性（日 報1992 — 23967A)，但完全未知如本發明所示且有抑制= 神經的效果或使皮膚溫度下降的效果。 、制父感 :實施=交感神經抑制劑係含有】，8—桉樹 有效成刀。上述有效成分會自交感神經抑制财揮發，若 使用者吸人其香氣，則實現上述之交感神經抑制效$ 感神經抑制劑可僅由有效成分 果百效成刀所構成’但只要為不妨礙效 果之範圍的量，則亦可含有稀釋劑、助劑、添加劑等任章 其他成分。若適當選擇所欲之添加 。 寻且ι 3有父感神經 ㈣劑，則可將交感神經抑制劑製成化妝料、醫藥品、準 :二!：料、雜貨等而使用。即，可將交感神經抑 1劑1成具有交感神經抑制效果的化妝料等。 _另方面右於化妝料等之一定之組成物添加交感神 )抑制劑貝J可賦予s亥組成物交感神經抑制效果。即，亦 可於化妝料等添加交感神經抑制劑，製成具有交感神經抑 制效果之化妝料等。進而，若於衣物、雜貨類等使其浸透 或附著有交感神經抑制劑’則由於上述有效成分會從浸透 或附著之交感神經抑制劑中揮發，故而可賦予衣物、雜貨 等交感神經抑制效果。 父感神”.i抑制劑中之有效成分之含量並無特別限定， T為G.QG()1質量％以上⑽質量％以下，更佳A 0.001質 量％以上50質量％以下’再更佳為〇 〇1質量％以上3〇質量 %以下。 201212949 又，於將交感神經抑制劑添加於化妝料、醫 組成物而賦予交感神經抑制效 、时寺之 經抑制劑中之有效成分的含量齡 α神 J 3重較佳為0.0001質量0/〇 質量％以下，更佳為0.001質 買量％以上50質量％以下，進 較佳為〇.〇1質量％以上30質量％以下。 進而 進而’於將交感神經抑制 】劑添加於化妝料、醫藥笑 之組成物中而賦予交感神經抑 、 ^ ^ , . 效果之情形時，組成物中 之父感神經抑制劑之調配量較 平乂佳為〇· 00 1質量％以上丨〇〇 量。/。以下，尤佳為0.003質量％以上30質量％以下。 本、實施形態之皮膚溫度下降劑含有1，8-按樹油作為有 效成& °上4有效成分會從皮膚溫度下降财揮發，若使 用者吸入其香& ’則實現上述之皮膚溫度下降效果。皮膚 溫度下降劑可僅由有效成分所構成，但只要為不妨礙效果 之範圍的量，則亦可含右絲轉：龙丨 、 力J 3有稀釋劑、助劑、添加劑等任意其 他成分。若適當撰堪舶, 遊擇所奴之添加劑等並且含有皮膚溫度下 降劑則可將皮膚溫度下降劑製成化妝料、醫藥品、準藥 。°食。0飲料、雜貨等而使用❶即，可將皮膚溫度下降 劑製成具有皮膚溫度下降效果的化妝料等。 另方面，右於化妝料等之一定之組成物添加皮膚溫 度下降劑貝’]可賦予該組成物皮膚溫度下降效果。即，可 於化妝料等添加皮膚溫度下降劑，製成具有皮膚溫度下降 效果的化妝料等。進而，若於衣物、雜貨類等使其浸透或 iw 度下降劑’則上述有效成分會從浸透或附著 之皮膚恤度下降劑中揮發，因此可賦予衣物、雜貨等皮膚 8 201212949 溫度下降效果。 皮膚溫度下降劑中之有效成分的含量並無特別限定， 較佳為0.0001質量。/。以上100質量％以下，更佳為〇⑽ 量％以上50質量％以下’再更佳為G Q1質量％以上3 %以下。 貝1 又，於將皮膚溫度下降劑添加於化妝料、醫藥之 組成物而賦予皮膚溫度下降效果之情形時，添加之: 度下降劑中之有效成分的含量較佳為〇 〇〇〇1質量％以上；〇 質量％以下，更佳為0.001質量％以上5〇質量％以下 佳為0.01質量。/〇以上30質量％以下。 進而’於將皮膚溫度下降劑添加於化妝料 '醫藥 之組成物中而賦予皮膚溫度下降效果之情料，組成:中 之皮膚溫度下降劑的調配量較佳為〇.G(H質量％以上⑽ 量％以下，尤佳為0.003質量％以上3〇質量％以下。 只要可達成本發明之效果，則本實施形態之交感神哩 抑制劑及皮膚溫度下降劑之形態並無特別限制，可以液 狀、糊狀、凝膠狀、固體狀等任意形態而使用。 〃要可達成本發明之效果’則本實施形態之交感 制劑及皮膚溫度下降劑之劑型並無特別限制，例如 劑等】舉劑、粉末劑、顆粒劑、噴霧劑、固體 剤4，但並不限定於該等。 喂 香水的㈣料’並無㈣’例如可列舉： 7古龍水等香氛，霜，乳液類，化妝水X. 摩用凝膠，按摩用霜，粉底… 妝水，按 箱叔底頰，蜜粉，口紅，肥息，洗髮 201212949 精一潤絲精類，沐浴露，潤膚露，香體粉類，喷霧，沐浴 劑等。 進而’例如’若將本實施形態之交感神經抑制劑或皮 膚/盟度下降劑次透或附著於芳香劑、除臭劑、香熏躐燭、 熏香、文具、錢包、提包、鞋子等任意雜貨類，或例如内 衣、西服、帽子、長統襪、襪子等任意衣物，則上述有效 成为會從 >又透或附著之交感神經抑制劑或皮膚溫度下降劑 中揮發，因此，可賦予雜貨、衣物等交感神經抑制效果或 皮膚溫度下降效果。可於雜貨、衣服等之原料浸透或附著 本貫施形態之交感神經抑制劑或皮膚溫度下降劑，再由其 原料製作成製品，亦可於完成之製品浸透或附著本實施形 態之交感神經抑制劑或皮膚溫度下降劑。 再者，已例示本實施形態之交感神經抑制劑及皮膚溫 度下降劑的各種使用態樣，但並不限定於該等，只要可達 成本發明之效果，則可以任意之態樣而使用。 以下所示實施例並進而加以詳細說明。 將1，8 —桉樹油以檸檬酸三乙酯稀釋成濃度〇 〇丨質量％ 作為測試試樣而使用，並研究測試試樣之香氣對交感神經 之活動及皮膚溫度所造成的影響。 1，8 —按樹油係使用高砂香料工業股份有限公司製造。 首先’對於本實施例中為確認交感神經抑制效果而採 用的測试方法進行說明。 (關於交感神經活動測定測試之方法） 跳的間隔或血塵於安靜時亦發生複雜變動，由以交 10 201212949 感神經及副交感神經a此圭 计 代表之複數個系統所主。田μ· τ 知，藉由將心跳的間隔…％ 凡所支配。因此可 的變動（血壓波動）進行,§定^ W波動）或血壓 硬仃頻率分析可算出各系 心跳間隔波動之高頻成 、 又 志-、日人 战刀表不副父感神經活性，低頻成分 表不混合交感神經系 &领成刀 ^交感神經糸統之活性，另一方 面’收縮期之血壓湓叙4 , 乃 71 ^ m _ 氏頻成分表示交感神經活性（早 野順一郎。循環器官科 、平 34，347— 356，1993 )。 因此’使用分析軟體對收缩期之血m + 勿析，根據其低頻成分（s °眚 動進行卜… ）之強度而對交感神經活 効進订疋2；，並評價測 之影響。 、-1 W樣之香氣對交感神經活動造成 /本實施例中，以8名2〇多歲之女性為受試者。預先 向焚試者說明測試内容，並 ^ 以書面形式獲得同意參加測試。 實施物於設定為溫度说、濕度4—濕室内 於受試者之手腕橈骨靜脈部安裝張力測量感測器 C tonometry sens〇r)，並連接於 势 、届人皿測 i§( patient monitor) &血壓。病人監測器係、使用omrqn C0LIN股份有 限公司製造之BP5〇8。自病人監測器將連續血壓測定資料輸 :個：電腦：纟用自主神經系統活性分析軟體對收縮期血 之> 動進行功率譜分析，並根據其低頻成分（sbp— 之強度對交感神經活動進行定旦 里。自主神經系活性分析軟 體係使用大日本住友製筚評 衣条月又份有限公司製造之Fluclet WT。將聞到香氣之情形與未聞香氣之情形時的_〜值 201212949 進行比較，並評價測 影響。 硪樣之香氣對交感神經活動造成之 於使受試者聞到 入棉花並貼於受試者之；、形時，將5 a】之測試試樣滲 氣。於未聞到香氣鼻下，自發呼吸的同時使其聞到香 ,HJ3认^ 月形時僅將棉花貼於受試老之皇下。 (關於交感神經.、壬包， 又忒者之鼻下。 ,動測定測試之結果） 1，8 —桉樹油之香 1 !。結果係由將聞到香義V:感神經活動造成之影響示於圖 氣之情形之SBP—LF# 1形之SBP—LF值除以未聞到香 於該SBP-LF比大於*算出的SBP—LF比表示。並判斷 於小於1之m ; 1之情形時，交感神經之活動活性化， J於1之情形日夺，鎮靜化。 根據圖1所明墟 時，SBP—LFI+微 ；竭到I，8—桉樹油之香氣之情形 可去1 得小於丨’交感神經之活動鎮靜化。因此 知，::8-桉樹油抑制交感神經之活動。 著f子於本實形態十為確認皮膚溫度下降效 用的測試方法進行說明。 (關於皮膚溫度測定測試之方法） ;本實施例中，以8名2G多歲之女性為受試者。預先 °式者說月測5式内容’並以書面形式獲得同意參加測試。 測試係於設定為溫度2rc、濕度45%之恒溫值濕室内 實施。 將皮膚溫度感測器貼附於受試者之面頰、手指尖 3 胸。卩，並連接至溫度監測器，連續測定皮膚溫度。溫 度監測器係使用NIKKISO— THERM股份有限公司製造之 12 201212949 N542R^將皮膚溫度資料輸入個人電腦，並將皮膚溫度幾乎 無變化之胸部皮膚溫度作為基準溫度，算出面頰及手指尖 之皮膚溫度變化量《將聞到香氣之情形與未聞到香氣之情 形之面頰、手指尖之皮膚溫度變化量進行比較，並評價測 試試樣之香氣對皮膚溫度造成之影響。 於使受試者聞到香氣之情形時，將5" 1之測試試樣滲 入棉花並貼於受試者之鼻下，自發呼吸的同時使其聞到香 氣。於未聞到香氣之情形時僅將棉花貼於受試者之鼻下。 (關於皮膚溫度測定測試之結果） 圖2及圖3係表示皮膚溫度測定測試之結果的圖。 結果係由自聞到香氣之情形時之皮膚溫度變化量減去 未聞到香氣之情形時之皮膚溫度變化量的值表示。並判斷 於忒值為正值之情形時，使皮膚溫度上升，為負值之情形 時’使皮膚溫度下降。 圖2所示’已知1，8 一按樹油具有使受試者之面頰之 皮膚溫度下降的效果。 又，如圖3所示，已知丨，8 —桉樹油具有使受試者之手 才曰尖之皮膚溫度下降的效果。 以下’對含本貫施例之交感神經抑制劑及皮膚溫度下 降劑的各種化妝料、雜貨類、食品之實施例，進而衣物等 斤使用之纖維類之實施例加以詳細說明但本發明並不限 定於該等。 化妝水 質量％ (1)甘油 ，η 13 201212949 (2 )二丙二醇 2.0 (3 )聚乙二醇一60氫化蓖麻油 0.3 (4) 木糖醇 3.0 (5) 抗壞血酸 0.005 (6 )磷酸氫三納（edetate trisodium ) 0.1 (7) 染料 0.1 (8) 1,8—桉樹油 0.05 (9 )純化水 剩餘量 合計 100 乳液 質量％ (1 )乙醇 10.0 (2)甘油 3.0 (3 ) 丁二醇 2_0 (4)聚乙二醇 3.0 (5 )羧乙烯聚合物 0.1 (6) 丙烯酸/丙烯酸烷基酯共聚物 0.1 (7) 氩氧化鉀 0.1 (8) 環甲聚石夕氧烧（cyclomethicone) 4.0 (9) 角鯊烷 2.0 (10) 球狀聚乙烯 2.0 (11 )薄荷腦 0.5 (12)藥劑 1.0 (13 )對羥苯曱酸酯 0.1 (14 )磷酸氫三鈉 0.1 14 201212949 (15) 顏料 0.1 (16) 1，8 —桉樹油 0.05 (1 7 )純化水 剩餘量 合計 100 霜 質量％ (1 )甘油 10.0 (2 ) 丁二醇 5.0 (3 )卡波姆（carbomer ) 0.1 (4) 氫氧化鉀 0.2 (5) 硬脂酸 2.0 (6) 硬脂酸甘油酯 2.0 (7 )異硬脂酸甘油酯 2.0 (8) 凡士林 5.0 (9) 防腐劑 0.1 (10) 抗氧化劑 0.1 (11) 1,8 —桉樹油 0.3 (12) 螯合劑 1.0 (13 )顏料 0.01 (14) 硬脂醇 2.0 (15) 山喻醇（BehenylAlcohol) 2.0 (16) 棕櫚硬化油 2.0 (17) 角鯊烷 10_0 (18) 4_甲氧基水楊酸鉀 3.0 (19 )純化水 剩餘量 15 201212949 合計 100 霜 質量％ (1 )甘油 3.0 (2 )二丙二醇 7.0 (3 )聚乙二醇 3.0 (4 )硬脂酸甘油酯 3.0 (5 )異硬脂酸甘油酯 2.0 (6 )硬脂醇 2.0 (7 )山蝓醇 2.0 (8 )液態石蠟 7.0 (9 )環曱聚矽氧烷 3.0 (1 0 )二曱聚矽氧烷 1.0 (11 )甲氧基肉桂酸辛酯 0.1 (1 2 )玻尿酸鈉 0.05 (1 3 )防腐劑 0.1 (14)抗氧化劑 0.1 (15 ) 1，8 —桉樹油 0.4 (1 6 )螯合劑 1.0 (1 7 )顏料 0.01 (1 8 )純化水 剩餘量 合計 100 凝膠 質量％ (1 )乙醇 10.0 (2 )甘油 5.0 16 201212949 (3 ) 丁二醇 5.0 (4)卡波姆 0.5 (5 )胺基甲基丙醇 0.3 (6) 聚乙二醇一60氫化蓖麻油 0.3 (7) 薄荷腦 0.02 (8) 防腐劑 0.05 (9) 螯合劑 1.0 (10) 1，8 -桉樹油 0.1 (11 )純化水 剩餘量 合計 100 喷霧 質量％ (1 )甘油 2.0 (2)二丙二醇 2.0 (3 )聚乙二醇一60氫化蓖麻油 0.3 (4)羥基丙基/5環糊精 1.0 (5 )防腐劑 0.1 (6) 螯合劑 1.0 (7) 染料 0.1 (8 ) 1，8 —按樹油 0.2 (9)純化水 40.0 (10 )液化石油氣 剩餘量 合計 100 喷霧 質量％ (1 )醇 15.0 17 201212949 (2 ) 丁二醇 2.0 (3 )甘油 1.0 (4)聚丙二醇一13癸基十四醇聚醚一24 0.1 (5 )載銀沸石 1.0 (6) 螯合劑 1.0 (7 )染料 0.3 (8 ) 1，8 —桉樹油 0_15 (9 )液化石油氣 40.0 (1 0 )純化水 剩餘量 合計 100 喷霧 質量％ (1 )乙醇 60.0 (2)乳酸薄荷 i旨（menthyllactate) 0.1 (3 )乳酸鈉 0.1 (4 )生育酚乙酸酯 0.01 (5 )乳酸 0.01 (6 )咖啡因 0.01 (7) 茴香萃取物 1.0 (8 )金縷梅萃取物 1.0 (9)蕺菜萃取物 1.0 (1 〇 )二丙二醇 1.0 (11 )氮氣 0.9 (12)聚氧乙烯聚氧丙烯癸基十四烷基醚 1.0 (13 ) 丁二醇 2.0 18 201212949 (14)生育酚 0.05 (15 ) 1，8 —桉樹油 0.1 (1 6 )聚乙二醇一60氫化蓖麻油 0.1 (1 7 )純化水 剩餘量 合計 100 洗髮精 質量％ (1 ) 月桂基聚氧乙烯（3 )硫酸酯鈉鹽 (30%水溶液） 30.0 (2)月桂基硫酸酯鈉鹽（30%水溶液） 10.0 (3 )椰子油脂肪酸二乙醇醯胺 4.0 (4 )甘油 1.0 (5 )防腐劑 0.1 (6 ) 1，8 —按樹油 0.5 (7)色素 0.1 (8 )金屬離子封阻劑 0.1 (9 ) pH調整劑 0.5 (1 0 )純化水 剩餘量 合計 100 潤絲精 質量％ (1 )聚矽氧油 3.0 (2 )液態石蠟 1.0 (3 )十六醇 1.5 (4 )十八醇 1.0 (5 )硬脂基三甲基氣化銨 0.76 201212949 Further, eucalyptus oil is known to have antiallergic activity (Japanese Journal 1992-23967A), but it is completely unknown as shown in the present invention and has an effect of suppressing nerves or lowering skin temperature. , fatherhood: implementation = sympathetic inhibitor system contains], 8 - eucalyptus effective knife. The above-mentioned active ingredient will volatilize from the sympathetic nerve suppression. If the user inhales the aroma, the above-mentioned sympathetic inhibition effect can be achieved. The sensory inhibitor can be composed only of the active ingredient, but it is not hindered. The amount of the effect range may also contain other components such as diluents, auxiliaries, and additives. If you choose the right one, you can add it. If you find ι 3 with a paternal nerve (4), you can use the sympathetic inhibitor as a cosmetic, pharmaceutical, and standard: second!: material, groceries, etc. That is, the sympathetic nerve inhibitor can be made into a cosmetic having a sympathetic suppression effect or the like. _In other respects, the sympathetic nerve is added to a certain composition such as a cosmetic material. The inhibitor B can impart a sympathetic inhibition effect to the s composition. In other words, a sympathetic inhibitor can be added to a cosmetic or the like to prepare a cosmetic having a sympathetic suppression effect. In addition, when the sympathetic inhibitor is adhered or adhered to clothing, miscellaneous goods, etc., the active ingredient is volatilized from the sympathetic inhibitor that has been permeated or adhered, so that a sympathetic suppression effect such as clothing or miscellaneous goods can be imparted. The content of the active ingredient in the inhibitor of the father is not particularly limited, and T is G.QG () 1% by mass or more (10)% by mass or less, more preferably A 0.001% by mass or more and 50% by mass or less. It is 〇〇1% by mass or more and 3% by mass or less. 201212949 In addition, the sympathetic inhibitor is added to a cosmetic or a medical composition to impart sympathetic inhibitory effects, and the age of the active ingredient in the inhibitor of Shiji Temple The α god J 3 weight is preferably 0.0001 mass%/〇 mass% or less, more preferably 0.001 mass% or more and 50 mass% or less, more preferably 〇.〇1 mass% or more and 30 mass% or less. Further, When the sympathetic nerve inhibitor is added to the composition of the cosmetic or the medical smile to impart sympathetic inhibition, ^ ^ , . , the effect of the composition of the paternal neuroinhibitor is better than that of the sympathetic inhibitor. 〇· 00 1% by mass or more 。. The following is particularly preferably from 0.003 mass% to 30 mass%. The skin temperature lowering agent of the present embodiment contains 1,8-as a tree oil as an effective ingredient. °The upper 4 active ingredients will be from the skin temperature The volatilization of the money is volatilized, and if the user inhales the scent & ', the above-mentioned skin temperature lowering effect is achieved. The skin temperature lowering agent may be composed only of the active ingredient, but may be right as long as it does not hinder the range of the effect. Silk transfer: Longjing, force J 3 has any other ingredients such as thinner, auxiliaries, additives, etc. If appropriate, you can make a skin temperature lowering agent if you want to use the additive, etc. Cosmetics, pharmaceuticals, and quasi-drugs. Use of foods such as beverages, miscellaneous goods, etc., can be used as a cosmetic material having a skin temperature lowering effect, etc. The addition of the skin temperature-lowering agent to the composition can impart a skin temperature lowering effect to the composition. That is, a skin temperature-lowering agent can be added to a cosmetic or the like to prepare a cosmetic having a skin temperature lowering effect, and the like. If the clothes, miscellaneous goods, etc. are soaked or the iw degree reducing agent', the above-mentioned effective ingredients will volatilize from the skin-degrading agent which is soaked or adhered, so that clothes, groceries, etc. can be given. The amount of the active ingredient in the skin temperature-lowering agent is not particularly limited, but is preferably 0.0001% by mass or more, preferably 100% by mass or less, more preferably 〇(10)% by mass or more and 50% by mass or less. More preferably, G Q1% by mass or more and 3% or less. In addition, when a skin temperature lowering agent is added to a cosmetic or a medical composition to impart a skin temperature lowering effect, it is added: The content of the component is preferably 〇〇〇〇1% by mass or more; 〇% by mass or less, more preferably 0.001% by mass or more and 5% by mass or less, preferably 0.01% by mass or more than 30% by mass or less. The temperature-reducing agent is added to the composition of the cosmetic material to impart a skin temperature-lowering effect, and the composition of the skin temperature-lowering agent is preferably 〇.G (H mass% or more (10)% by volume or less. It is particularly preferably 0.003 mass% or more and 3 mass% or less. The form of the sympathetic inhibitor and the skin temperature lowering agent of the present embodiment is not particularly limited, and may be used in any form such as a liquid, a paste, a gel or a solid. The dosage form of the sympathetic preparation and the skin temperature lowering agent of the present embodiment is not particularly limited, and examples thereof include an agent, a powder, a granule, a spray, and a solid 剤4, but Not limited to these. (4) Feeding the perfume (4) There are no (four) 'for example: 7 cologne, cream, lotion, lotion X. Moisturizing gel, massage cream, foundation... Make-up water, press the box uncle, Honey powder, lipstick, fat, shampoo 201212949 Fine one moisturizing essence, shower gel, body lotion, body powder, spray, body wash and so on. Further, 'for example, if the sympathetic inhibitor or the skin/classification agent of the present embodiment is sub-permeated or attached to a fragrance, a deodorant, an aromatherapy candle, an incense, a stationery, a wallet, a bag, a shoe, or the like. For groceries, or any clothing such as underwear, suits, hats, stockings, socks, etc., the above-mentioned effective scent will be volatilized from the sympathetic inhibitor or skin temperature reducing agent that is permeable or attached, and therefore, can be given to groceries. , sympathetic inhibition effect such as clothing or skin temperature drop effect. The sympathetic nerve inhibitor or the skin temperature-decreasing agent may be impregnated or adhered to the raw materials of the groceries, clothes, and the like, and then the raw material may be made into a product, or the finished product may be saturated or adhered to the sympathetic nerve suppression of the embodiment. Agent or skin temperature reducing agent. Further, although various aspects of the use of the sympathetic inhibitor and the skin temperature reducing agent of the present embodiment have been exemplified, the present invention is not limited thereto, and may be used in any form as long as it can attain the effect of the invention. The embodiments shown below are further described in detail. The 1,8-eucalyptus oil was diluted with triethyl citrate to a concentration of 〇 〇丨 mass % as a test sample, and the effect of the aroma of the test sample on the activity of the sympathetic nerve and the skin temperature was investigated. 1,8—Used in the tree oil system, manufactured by Takasago Perfumery Industrial Co., Ltd. First, the test method used to confirm the sympathetic suppression effect in the present embodiment will be described. (Methods for sympathetic activity measurement test) Complex intervals are also observed when the interval of hopping or blood dust is quiet. It is dominated by a plurality of systems represented by the sensation of the sensory and parasympathetic nerves. Tian μ· τ knows that by the interval of the heartbeat...%. Therefore, the variability (blood pressure fluctuations), § ^ W 波动 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或 或The sympathetic nervous system & Ping 34, 347-356, 1993). Therefore, using the analysis software, the systolic blood m + is not analyzed, and the sympathetic activity is predicted according to the intensity of the low-frequency component (s ° 眚 眚...), and the influence of the measurement is evaluated. , -1 W-like aroma caused by sympathetic nerve activity / In this example, 8 women over 2 years old were used as subjects. Explain the test content to the inspector in advance, and obtain the consent to participate in the test in writing. The implement is installed in the temperature, humidity 4 - wet room in the wrist of the subject, the tension measuring sensor C tonometry sens〇r), and connected to the potential, the patient test i § (patient monitor) & blood pressure. The patient monitor system uses BP5〇8 manufactured by Omrqn C0LIN Co., Ltd. From the patient monitor, the continuous blood pressure measurement data is transmitted: computer: 自主 自主 自主 自主 自主 自主 自主 收缩 收缩 收缩 收缩 收缩 收缩 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率 功率In the case of Dingdan, the soft system of autonomic nervous system activity analysis uses the Fluclet WT manufactured by Dainippon Sumitomo, Ltd., which is based on the scent of the scented scent. Compare and evaluate the effect of the test. The aroma of the sample is caused by the sympathetic activity caused by the subject to smell the cotton and attached to the subject; when the shape is measured, the test sample of 5 a] is infiltrated. I didn't smell the aroma under the nose, and spontaneously breathed it while smelling it. HJ3 recognized the moon shape and only attached the cotton to the old Emperor. (About the sympathetic nerves, the shoulder bag, and the nose under the nose) The result of the dynamic measurement test) 1,8 - the fragrance of eucalyptus oil! The result is SBP-LF# 1 type SBP which will be described in the case of scented V: sensory nerve activity - the LF value divided by the unscented SBP-LF ratio The ratio of SBP-LF calculated in * is judged to be less than 1 m; in the case of 1 , the activity of the sympathetic nerve is activated, and J is sedated and sedated in the case of 1; - LFI + micro; exhausted to the aroma of I, 8 - eucalyptus oil can go to 1 to be less than the sympathetic activity of 丨 sympathetic nerves. Therefore, know:: 8 - eucalyptus oil inhibits the activity of sympathetic nerves. The test method for confirming the skin temperature drop effect is explained. (About the method of skin temperature measurement test); In this embodiment, 8 women of 2G years old are used as subjects. Type 5 content 'and agreed to participate in the test in writing. The test was carried out in a constant temperature wet room set to a temperature of 2rc and a humidity of 45%. Attach the skin temperature sensor to the subject's cheeks, fingertips 3 chest卩, and connected to the temperature monitor to continuously measure the skin temperature. The temperature monitor is used to import the skin temperature data into the personal computer using NIKKISO-THERM Co., Ltd. 12 201212949 N542R^, and the skin temperature is almost unchanged. The skin temperature is used as the reference temperature to calculate the amount of skin temperature change on the cheeks and the tip of the finger. "The smell of the smell is compared with the amount of skin temperature change on the cheeks and fingertips where the aroma is not detected, and the aroma of the test sample is evaluated. Effect on skin temperature. When the subject smells the aroma, the test sample of 5" 1 is infiltrated into the cotton and attached to the nose of the subject, and spontaneously breathes while smelling the aroma. When the aroma is not detected, only the cotton is attached to the nose of the subject. (Results of the skin temperature measurement test) Figs. 2 and 3 are views showing the results of the skin temperature measurement test. The result is expressed as the value of the change in skin temperature from the time when the aroma is detected minus the amount of change in the skin temperature when the aroma is not detected. It is judged that when the 忒 value is a positive value, the skin temperature is raised, and when it is a negative value, the skin temperature is lowered. As shown in Fig. 2, it is known that 1,8 a tree oil has an effect of lowering the skin temperature of the cheek of the subject. Further, as shown in Fig. 3, it is known that 丨8-eucalyptus oil has an effect of lowering the skin temperature of the subject's hand. Hereinafter, the examples of the various cosmetic materials, miscellaneous goods, foods, and the fibers used in the clothes including the sympathetic inhibitors and skin temperature lowering agents of the present embodiment will be described in detail, but the present invention is not Limited to these. % of lotion (1) glycerin, η 13 201212949 (2) dipropylene glycol 2.0 (3) polyethylene glycol-60 hydrogenated castor oil 0.3 (4) xylitol 3.0 (5) ascorbic acid 0.005 (6) hydrogen phosphate tris (edetate trisodium ) 0.1 (7) Dyestuff 0.1 (8) 1,8-eucalyptus oil 0.05 (9) Total amount of purified water Total 100 Emulsion mass % (1) Ethanol 10.0 (2) Glycerol 3.0 (3) Butanediol 2_0 ( 4) Polyethylene glycol 3.0 (5) Carboxyvinyl polymer 0.1 (6) Acrylic acid/alkyl acrylate copolymer 0.1 (7) Potassium arsenate 0.1 (8) Cyclomethicone 4.0 (9) ) Squalane 2.0 (10) Spherical polyethylene 2.0 (11) Menthol 0.5 (12) Medicament 1.0 (13) p-Hydroxybenzoate 0.1 (14) Trisodium hydrogen phosphate 0.1 14 201212949 (15) Pigment 0.1 ( 16) 1,8 — Eucalyptus oil 0.05 (1 7 ) Total amount of purified water Total 100 Cream mass % (1 ) Glycerin 10.0 (2 ) Butanediol 5.0 (3) Carbomer 0.1 (4) Potassium hydroxide 0.2 (5) Stearic acid 2.0 (6) Glyceryl stearate 2.0 (7) Glyceryl isostearate 2.0 (8) Vaseline 5.0 (9) Preservative 0.1 (10) Antioxidant 0.1 (11) 1,8 — Eucalyptus oil 0.3 (12) Chelating agent 1.0 (13) Pigment 0.01 (14) Stearyl alcohol 2.0 (15) Behenyl Alcohol 2.0 (16) Palm hardened oil 2.0 (17) Squalane 10_0 (18) 4_Methoxysalicylate 3.0 (19) Remaining amount of purified water 15 201212949 Total 100 Cream mass% (1) Glycerin 3.0 (2) Dipropylene glycol 7.0 (3) Polyethylene glycol 3.0 (4) Glyceryl stearate 3.0 (5) Isostearic acid glycerin Ester 2.0 (6) Stearyl alcohol 2.0 (7) Kaempferol 2.0 (8) Liquid paraffin 7.0 (9) Cyclopolyoxyalkylene 3.0 (1 0 ) Dioxane 1.0 (11) Methoxycinnamate Acid octyl ester 0.1 (1 2 ) sodium hyaluronate 0.05 (1 3 ) preservative 0.1 (14) antioxidant 0.1 (15 ) 1,8 — eucalyptus oil 0.4 (1 6 ) chelating agent 1.0 (1 7 ) pigment 0.01 (1 8 ) Purified water total amount 100 Gel mass% (1) Ethanol 10.0 (2) Glycerol 5.0 16 201212949 (3) Butanediol 5.0 (4) Carbomer 0.5 (5) Aminomethylpropanol 0.3 (6) Poly Ethylene Glycol-60 Hydrogenated Castor Oil 0.3 (7) Menthol 0.02 (8) Preservative 0.05 (9) Chelating Agent 1.0 (10) 1,8 - Eucalyptus Oil 0.1 (11) Total Purified Water Remaining 100 Spray Mass % (1) Glycerin 2.0 (2) Dipropylene 2.0 (3) Polyethylene glycol-60 hydrogenated castor oil 0.3 (4) Hydroxypropyl/5 cyclodextrin 1.0 (5) Preservative 0.1 (6) Chelating agent 1.0 (7) Dye 0.1 (8 ) 1,8 — According to tree oil 0.2 (9) purified water 40.0 (10) total amount of liquefied petroleum gas remaining 100 spray mass% (1) alcohol 15.0 17 201212949 (2) butanediol 2.0 (3) glycerol 1.0 (4) polypropylene glycol-13 Mercaptotetradecyl ether polyether-24 0.1 (5) Silver-loaded zeolite 1.0 (6) Chelating agent 1.0 (7) Dye 0.3 (8 ) 1,8 — Eucalyptus oil 0_15 (9) Liquefied petroleum gas 40.0 (1 0 ) Purification Total water remaining 100 Spray mass % (1) Ethanol 60.0 (2) Lactic acid Mint i (menthyllactate) 0.1 (3) Sodium lactate 0.1 (4) Tocopherol acetate 0.01 (5) Lactic acid 0.01 (6) Caffeine 0.01 (7) Fennel Extract 1.0 (8) Witch Hazel Extract 1.0 (9) Amaranth Extract 1.0 (1 〇) Dipropylene Glycol 1.0 (11) Nitrogen 0.9 (12) Polyoxyethylene Polyoxypropylene decyltetradecane Ether 1.0 (13) butanediol 2.0 18 201212949 (14) Tocopherol 0.05 (15 ) 1,8 — Eucalyptus oil 0.1 (1 6 ) Polyethylene glycol-60 hydrogenated castor oil 0.1 (1 7 ) Purified water remaining Total 100 shampoo quality (1) Lauryl polyoxyethylene (3) sulfate sodium salt (30% aqueous solution) 30.0 (2) Lauryl sulfate sodium salt (30% aqueous solution) 10.0 (3) Coconut oil fatty acid diethanolamine 4.0 (4) Glycerin 1.0 (5) Preservative 0.1 (6 ) 1,8 —According to tree oil 0.5 (7) Pigment 0.1 (8 ) Metal ion blocker 0.1 (9 ) pH adjuster 0.5 (1 0 ) Purified water total amount 100 Moisturizing essence% (1) Polyoxygenated oil 3.0 (2) Liquid paraffin 1.0 (3) Cetyl alcohol 1.5 (4) octadecyl alcohol 1.0 (5) Stearyl trimethylated ammonium oxide 0.7
19 S 201212949 (6 )甘油 3.0 (7) 1，8—桉樹油 0.5 (8 )色素 0.1 (9 )防腐劑 0.05 (1 0 )純化水 剩餘量 合計 100 沐浴露 質量％ (1 )月桂酸 2.5 (2 )肉豆蔻酸 5.0 (3 )棕櫚酸 2.5 (4 )油酸 2.5 (5 )椰油醯基二乙醇醯胺 1.0 (6 )甘油 20.0 (7 )氫氧化鉀 3.6 (8 )染料 0.1 (9 ) 1，8 —按樹油 0.5 (1 0 )金屬離子封阻劑 0.1 (11 )純化水 剩餘量 合計 100 香氛 質量％ (1 )醇 75.0 (2 )二丙二醇 5.0 (3) 1，8—桉樹油 10.0 (4 )抗氧化劑 8.0 20 201212949 (5) 色素 0.01 (6) 紫外線吸收劑 0.01 (7) 純化水 剩餘量 合計 100 室内: 香氛 質量％ (1) 醇 80.0 (2) 抗氧化劑 5.0 (3) 1，8 —按樹油 3.0 (4) 3 —甲基_3—曱氧基丁醇 5.0 (5) 二亞苄基山梨醇 5.0 (6) 純化水 剩餘量 合計 100 熏香 質量％ (1) 紅楠粉(Machilus thunbergii power) 75.5 (2) 苯曱酸鈉 15.5 (3) 1，8 —按樹油 5.0 (4) 桉樹油 1.0 (5) 純化水 剩餘量 合計 100 沐浴劑 質量％ (Ο 硫酸鈉 45.0 (2) 碳酸氫鈉 45.0 (3) 喜壽花油（Hyssopus officinalis oil ) 9.0 (4) 1，8 —按樹油 1.0 21 201212949 合計 按摩用凝膠 (1 )赤藻糖醇 (2 )咖α非因 (3 )黃柏萃取物 (4 )甘油 (5 )羧乙烯聚合物 (6 )聚乙二醇400 (7 )磷酸氫三鈉 (8)聚氧化烯（10)曱 (9 )角鯊烷 (1 0 )氫氧化鉀 (11) 1，8—桉樹油 (1 2 )純化水 合計 按摩霜 (1 )固體石蠟 (2 )蜂蠟 (3 )凡士林 (4 )液態石蠟 (5) 1，3 — 丁二醇 (6 )單硬脂酸甘油画旨 (7)聚氧化烯（20)山梨 (8 )硼砂 100 質量％ 2.0 5.0 3.0 50.0 0.4 30.0 0.1 聚矽氧烷共聚物 2.0 1.0 0.15 1.0 剩餘量 100 質量％ 5.0 10.0 15.0 41.0 4.0 2.0 糖醇酐單月桂酸酯2.0 0.2 22 201212949 (9 )吻j。非因 2.0 (1 0 )防腐劑 0.1 (11)抗氧化劑 0.1 (12 ) 1，8 —桉樹油 1.0 (1 3 )純化水 剩餘量 合計 100 芳香性纖維 於銅錢纖維素溶液（euproammonium cellulose)(纖維 素濃度為10質量％，銨濃度為7質量％，銅濃度為36質量 %)，於相對於纖維素質量為〇卜2〇質量％之範圍内添加内 包有本發明之交感神經抑制劑或皮膚溫度下降劑的微膠囊 :粒徑5〇心以下，以-桉樹油占微膠囊之比例為5。質 S%)並混合後，依據通常之濕式紡絲方法而紡絲，經精練 步驟、乾燥步驟，獲得芳香性纖維。 、 顆粒 (1)嚴糖素 (2 ) 1，8 —桉樹油 (3 )香料 (5)賦形劑（CEOLUS) (6 )麥芽糖醇 合計 錠劑（呕嚼型） (1 )肌醇 (2 )麥芽糖醇 質量％ 0.1 0.1 5.0 10.0 剩餘量 100 質量％ 11.0 21.0 23 201212949 (3 )蔗糖 0·5 (4)鮭魚精萃取物（DNA Na) 0.1 (5 )酵母萃取物 0.1 (6) 1，8—桉樹油 0·1 (7) 香料 5.0 (8 )賦形劑 剩餘量 合計 100 片劑 質量％ (1 )潤滑劑（蔗糖脂肪酸酯等） 1.0 (2)阿拉伯膠水溶液（5%) 2.0 (3 )酸味劑 1 · 0 (4)著色料 0.01 (5 ) 1，8 —桉樹油 0.1 (6 )糖類（粉糖或山梨糖醇等） 剩餘量 合計 100 糖果 質量％ (1 )砂糖 50.0 (2 )飴糖 47.95 (3 )有機酸 2.0 (4) 1，8 —桉樹油 0.05 合計 100 口香糖 質量％ (1 )砂糖 43.0 (2)原膠 30.95 24 201212949 (3 )葡萄糖 10.0 (4 )飴糖 16.0 (5 ) 1,8 —桉樹油 0.05 合計 100 調合香料 質量％ (1 ) 1，8 —按樹油 1.2 (2 )檸檬油 2.0 (3 )卑檸油 0.6 (4 ) α —松脂醇 2.0 (5 ) /3 _紫羅蘭酉同 2.0 (6 )沈香醇 10.0 (7 )橙花醇 2.0 (8)香葉草醇 10.0 (9)二氫茉莉酮酸曱酉旨（Hedione)(F irmenich ) 40.0 (10)橙花叔醇（nerolidol) 10.0 (11 )茉莉花精油 0.2 (1 2 )瑞香草油（thyme oil ) 0.8 (13)乙酸冰片酉旨（bornyl acetate) 1.8 (14 )二丙二醇 17.4 合計 100 調合香料 質量％ (1) 1，8—桉樹油 3.0 (2 )檸檬油 10.0 25 201212949 (3) 卑檸油 0.6 (4) α _松脂醇 3.0 (5) /5 —紫羅蘭酮 10.0 (6) 沈香醇 5.0 (7) 橙花醇 2.0 (8) 香葉草醇 20.0 (9) 二氫茉莉酮酸曱醋（Firmenich) 30.0 (l〇) α —己基桂皮搭 (hexyl cinnamic aldehyde) 2.0 (ID 茉莉花精油 0.2 (12) 瑞香草油 0.5 (13) 麝香T (高砂香料工業股份有限公司製造） 5.0 (14) 二丙二醇 8.7 合計 100 調合香料 質量％ (1) 1，8 —按樹油 10.0 (2) 檸檬油 2.0 (3) 佛手柑油 5.0 (4) 乙酸順一3 —己烯酯 0.1 (5) 香氛油（蘋果基底） 0.5 (6) 迷迭香油 0.3 (7) α —松脂醇 0.5 (8) /3 —紫羅蘭酮 1.0 26 201212949 (9 )沈香醇 4.0 (10)香葉草醇 2.0 (11 )苯乙醇 2.0 (12) 3_ (4 —第三丁基苯基）一2 —甲基丙醛5.0 (13) 新洋茉莉醛（Helional) 2.0 (14) 二氫茉莉酮酸甲醋（Firmenich) 20.0 (15) α —己基桂皮醛 2.0 (16) 茉莉花精油 0.1 (17) 瑞香草油 0.1 (18 )乙酸冰片酯 1.0 (19) Iso E Super ( IFF 公司製造） 5.019 S 201212949 (6) Glycerin 3.0 (7) 1,8-eucalyptus oil 0.5 (8 ) Pigment 0.1 (9 ) Preservative 0.05 (1 0 ) Total amount of purified water Total 100 Body lotion % (1 ) Lauric acid 2.5 ( 2) Myristic acid 5.0 (3) palmitic acid 2.5 (4) oleic acid 2.5 (5) cocoyl decyl diethanol decylamine 1.0 (6) glycerol 20.0 (7) potassium hydroxide 3.6 (8) dye 0.1 (9) 1,8 — by tree oil 0.5 (1 0 ) metal ion blocker 0.1 (11 ) purified water total amount 100 scent quality % (1 ) alcohol 75.0 (2 ) dipropylene glycol 5.0 (3) 1,8 - eucalyptus Oil 10.0 (4)Antioxidant 8.0 20 201212949 (5) Pigment 0.01 (6) UV absorber 0.01 (7) Total amount of purified water remaining 100 Indoor: Fragrance quality % (1) Alcohol 80.0 (2) Antioxidant 5.0 (3 1,8 — by tree oil 3.0 (4) 3 —methyl _3- methoxybutanol 5.0 (5) Dibenzylidene sorbitol 5.0 (6) Total amount of purified water Total 100 Incense quality % (1 ) Machilus thunbergii power 75.5 (2) Sodium benzoate 15.5 (3) 1,8 — According to tree oil 5.0 (4) Eucalyptus oil 1.0 (5) Total amount of purified water is 100 % by mass (Ο Sodium sulfate 45.0 (2) Sodium bicarbonate 45.0 (3) Hyssopus officinalis oil 9.0 (4) 1,8 — According to tree oil 1.0 21 201212949 Total massage gel (1) Alginitol (2) coffee alpha non-causine (3) cork extract (4) glycerol (5) carboxyvinyl polymer (6) polyethylene glycol 400 (7) trisodium hydrogen phosphate (8) polyoxyalkylene (10) ) 曱(9) squalane (10) potassium hydroxide (11) 1,8-eucalyptus oil (1 2) purified hydration massage cream (1) solid paraffin (2) beeswax (3) petrolatum (4) liquid Paraffin (5) 1,3 - Butanediol (6) Monostearic acid glycerin (7) Polyoxyalkylene (20) Yamanashi (8) Borax 100% by mass 2.0 5.0 3.0 50.0 0.4 30.0 0.1 Polyoxyalkylene copolymerization Material 2.0 1.0 0.15 1.0 Remaining amount 100% by mass 5.0 10.0 15.0 41.0 4.0 2.0 Sugar alcohol anhydride monolaurate 2.0 0.2 22 201212949 (9) Kiss j. Non-causal 2.0 (1 0 ) preservative 0.1 (11) Antioxidant 0.1 (12 ) 1,8 — Eucalyptus oil 1.0 (1 3 ) Total amount of purified water Total 100 Aromatic fiber in euproammonium cellulose (fibres) The concentration of the element is 10% by mass, the concentration of ammonium is 7% by mass, and the concentration of copper is 36% by mass. The sympathetic inhibitor or skin of the present invention is added to the range of 2% by mass relative to the mass of the cellulose. The microcapsule of the temperature reducing agent: the particle size is less than 5 〇, and the ratio of eucalyptus oil to the microcapsule is 5. After S%) and mixed, the yarn is spun according to the usual wet spinning method, and the sizing step and the drying step are carried out to obtain an aromatic fiber. , granules (1) glucosinolate (2) 1,8 - eucalyptus oil (3) perfume (5) excipient (CEOLUS) (6) maltitol total lozenge (vomit) (1) inositol (2) Maltitol mass% 0.1 0.1 5.0 10.0 Residual amount 100% by mass 11.0 21.0 23 201212949 (3) Sucrose 0·5 (4) Salmon extract (DNA Na) 0.1 (5) Yeast extract 0.1 (6) 1,8 - Eucalyptus oil 0·1 (7) Perfume 5.0 (8) Total amount of excipients 100 Tablets by mass% (1) Lubricant (sucrose fatty acid ester, etc.) 1.0 (2) Acacia aqueous solution (5%) 2.0 ( 3) Sour agent 1 · 0 (4) Coloring material 0.01 (5 ) 1,8 — Eucalyptus oil 0.1 (6 ) Sugar (powder or sorbitol, etc.) Total amount of remaining 100 Candy mass% (1) Sugar 50.0 (2 ) sugar 47.95 (3) organic acid 2.0 (4) 1,8 - eucalyptus oil 0.05 total 100 chewing gum mass% (1) sugar 43.0 (2) raw gum 30.95 24 201212949 (3) glucose 10.0 (4) sugar 16.0 (5) 1,8 — Eucalyptus oil 0.05 Total 100 Concentration of perfume quality % (1 ) 1,8 — According to tree oil 1.2 (2 ) Lemon oil 2.0 (3 ) Lime oil 0.6 (4 ) α — rosin alcohol 2.0 (5 ) /3 _ Violet 2.0 (6) linalool 10.0 (7) nerol 2.0 (8) geranyl alcohol 10.0 (9) Hedione (F irmenich ) 40.0 (10) nerolidol (nerolidol) 10.0 (11) Jasmine Essential Oil 0.2 (1 2 ) Thyme oil 0.8 (13) Borne acetate 1. 1.8 (14) Dipropylene glycol 17.4 Total 100 Blend perfume quality % (1) 1,8 - Eucalyptus oil 3.0 (2) Lemon oil 10.0 25 201212949 (3) Lime oil 0.6 (4) α _ rosinol 3.0 (5) /5 - Ionone 10.0 (6) Arginol 5.0 (7) Nertarol 2.0 ( 8) Geranol 20.0 (9) Dimensional jasmonic acid vinegar (Firmenich) 30.0 (l〇) α-hexyl cinnamic aldehyde 2.0 (ID Jasmine essential oil 0.2 (12) Revan oil 0.5 (13 ) Musk T (manufactured by Takasago Perfumery Industrial Co., Ltd.) 5.0 (14) Dipropylene glycol 8.7 Total 100 Blend of perfume quality % (1) 1,8 — According to tree oil 10.0 (2) Lemon oil 2.0 (3) Bergamot oil 5.0 ( 4) Acetic acid cis-3-hexenyl ester 0.1 (5) Fragrance oil (apple base) 0.5 (6) Rosemary oil 0.3 (7) α-rosinol 0.5 (8) /3 - ionone 1.0 26 201212949 (9) linalool 4.0 (10) geranyl alcohol 2.0 (11) phenylethyl alcohol 2.0 (12) 3_ (4 - tert-butylphenyl)-2-methyl Propionaldehyde 5.0 (13) New jasmine aldehyde (Helional) 2.0 (14) Dihydrojasmonic acid methyl vinegar (Firmenich) 20.0 (15) α-hexyl cinnamaldehyde 2.0 (16) Jasmine essential oil 0.1 (17) Revan oil 0.1 (18) borneol acetate 1.0 (19) Iso E Super (manufactured by IFF) 5.0
(20) 麝香T (高砂香料工業股份有限公司製造）20.0 (21 )二丙二醇 17.4 合計 100 【圖式簡單說明】 圖1係表示交感神經抑制效果測試之結果的圖。 圖2係表示面頰之皮膚溫度測定測試之結果的圖。 圖3係表示手指尖之皮膚溫度測定測試之結果的圖。 【主要元件符號說明】 無 27(20) Musk T (manufactured by Takasago Perfumery Co., Ltd.) 20.0 (21) Dipropylene glycol 17.4 Total 100 [Schematic description of the drawings] Fig. 1 is a graph showing the results of a sympathetic suppression effect test. Fig. 2 is a view showing the results of a skin temperature measurement test on the cheek. Fig. 3 is a view showing the results of a skin temperature measurement test of a fingertip. [Main component symbol description] None 27