JP2006096665A - 脊柱管狭窄症治療剤 - Google Patents

脊柱管狭窄症治療剤 Download PDF

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Publication number
JP2006096665A
JP2006096665A JP2002314084A JP2002314084A JP2006096665A JP 2006096665 A JP2006096665 A JP 2006096665A JP 2002314084 A JP2002314084 A JP 2002314084A JP 2002314084 A JP2002314084 A JP 2002314084A JP 2006096665 A JP2006096665 A JP 2006096665A
Authority
JP
Japan
Prior art keywords
nitric oxide
oxide synthase
spinal canal
therapeutic
canal stenosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002314084A
Other languages
English (en)
Japanese (ja)
Inventor
Takashi Takenobu
敬史 竹信
Yoshihisa Kamanaka
喜久 鎌中
Takaaki Obata
隆明 小畠
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP2002314084A priority Critical patent/JP2006096665A/ja
Priority to PCT/JP2003/013776 priority patent/WO2004039404A1/fr
Priority to AU2003275709A priority patent/AU2003275709A1/en
Publication of JP2006096665A publication Critical patent/JP2006096665A/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4458Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2002314084A 2002-10-29 2002-10-29 脊柱管狭窄症治療剤 Pending JP2006096665A (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2002314084A JP2006096665A (ja) 2002-10-29 2002-10-29 脊柱管狭窄症治療剤
PCT/JP2003/013776 WO2004039404A1 (fr) 2002-10-29 2003-10-28 Agent therapeutique pour la stenose de canal rachidien
AU2003275709A AU2003275709A1 (en) 2002-10-29 2003-10-28 Therapeutic agent for spinal canal stenosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002314084A JP2006096665A (ja) 2002-10-29 2002-10-29 脊柱管狭窄症治療剤

Publications (1)

Publication Number Publication Date
JP2006096665A true JP2006096665A (ja) 2006-04-13

Family

ID=32211603

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002314084A Pending JP2006096665A (ja) 2002-10-29 2002-10-29 脊柱管狭窄症治療剤

Country Status (3)

Country Link
JP (1) JP2006096665A (fr)
AU (1) AU2003275709A1 (fr)
WO (1) WO2004039404A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007511520A (ja) * 2003-11-13 2007-05-10 ザ ジェネラル ホスピタル コーポレーション 疼痛を治療するための方法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2597087B1 (fr) 2005-10-25 2016-03-30 Shionogi&Co., Ltd. Dérivés dihydrooxazine et tétrahydropyrimidine comme inhibiteurs de BACE 1
EP2147914B1 (fr) 2007-04-24 2014-06-04 Shionogi&Co., Ltd. Dérivés d'aminodihydrothiazine substitués par des groupes cycliques
JP5383483B2 (ja) 2007-04-24 2014-01-08 塩野義製薬株式会社 アルツハイマー症治療用医薬組成物
CA2727859C (fr) 2008-06-13 2016-11-01 Shionogi & Co., Ltd. DERIVE HETEROCYCLIQUE CONTENANT DU SOUFRE AYANT UNE ACTIVITE INHIBANT LA ß-SECRETASE
JPWO2010047372A1 (ja) 2008-10-22 2012-03-22 塩野義製薬株式会社 Bace1阻害活性を有する2−アミノピリミジン−4−オンおよび2−アミノピリジン誘導体
ES2590038T5 (es) 2009-12-11 2021-10-19 Shionogi & Co Derivado de oxazina
JP5766198B2 (ja) 2010-10-29 2015-08-19 塩野義製薬株式会社 縮合アミノジヒドロピリミジン誘導体
AU2011321427A1 (en) 2010-10-29 2013-05-02 Shionogi & Co., Ltd. Naphthyridine derivative
TW201247635A (en) 2011-04-26 2012-12-01 Shionogi & Co Oxazine derivatives and a pharmaceutical composition for inhibiting BAC1 containing them
US9540359B2 (en) 2012-10-24 2017-01-10 Shionogi & Co., Ltd. Dihydrooxazine or oxazepine derivatives having BACE1 inhibitory activity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266594A (en) * 1992-05-12 1993-11-30 Dawson Valina L Inhibitors of nitric oxide synthase and use thereof to prevent glutamate neurotoxicity
GB9425701D0 (en) * 1994-12-20 1995-02-22 Wellcome Found Enzyme inhibitors
WO1996021445A1 (fr) * 1995-01-13 1996-07-18 The General Hospital Corporation Procedes d'inhibition de maladies neurodegeneratives
US6110930A (en) * 1997-04-10 2000-08-29 Ono Pharmaceutical Co., Ltd. Condensed piperidine compound
WO2000034778A1 (fr) * 1998-12-04 2000-06-15 Welfide Corporation Pgt et apoptose
JP3927343B2 (ja) * 2000-01-12 2007-06-06 株式会社リコー 自動原稿送り装置及び画像読み取り装置
WO2001094311A1 (fr) * 2000-06-08 2001-12-13 Mitsubishi Pharma Corporation Cytoprotecteurs

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007511520A (ja) * 2003-11-13 2007-05-10 ザ ジェネラル ホスピタル コーポレーション 疼痛を治療するための方法

Also Published As

Publication number Publication date
WO2004039404A1 (fr) 2004-05-13
AU2003275709A1 (en) 2004-05-25

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