JP2006036679A - Cosmetic having hair-growing activity - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a cosmetic for promoting hair-growing. <P>SOLUTION: The cosmetic for hair-growing contains an essence of zooplankton, and one or more kinds of an essence of a seaweed, an essence of a mixture of stevia and Aralia cordata, and an essence of Agaricus blazei Murill. Preferably, the cosmetic is obtained by using krill as the zooplankton, and a mixture of Monostroma nitidum, Enteromorpha sp. and Ulva pertusa as the seaweed. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a cosmetic having a hair-growth effect.

Various cosmetics having a hair restoring action have already been studied and reported.
There is a finding that the extract of the mixture of stevia and udo synergistically increases the antioxidant activity of each. In addition, the antioxidant active substance in the extract of stevia and udo is considered to be a polyphenol group. As green algae, the extract of human rush (Monostroma nitidum), Aonori (Enteromorpha sp.) And Anaanaosa (Ulva pertusa) is also known for its hair growth effect. Stevia and Udo mixture extract is also effective for hair growth. Agaricus koji extract has also been known for its hair-growth effect since ancient times.

  JP-A-2003-160486 (Patent Document 1) has an effect of promoting hair growth by ingestion containing one or more selected from the following components (A) or (E) as active ingredients. Oral hair nurturing agent. (A) Fatty acid having an odd carbon chain length and its derivative (B) Alcohol and its derivative having an odd carbon chain length (C) Coleus genus, Ptychopetalum genus, Anemopaegma (Anemopaegma), Solanum, Styphnodendron, Dalbergia, Cynara, Aniba, Menthac, Yantu Genus, Sendensa, Potormophe, Eupatorium, Brosimun, Mikania, Carapa, Dipteryx, Simarouba, Ficus, Physalis, Boerhavia, and Guazuma Z and Genuine Z Plant and extract thereof (D) Genus Monostroma, Ulva, Caetorpha, Bryopsis, Caulerpa, Codium, Analipus Genus, Okinawa genus (Cladosiphon), genus Nemacytis, genus Lesonia, genus Durvillea, genus laria, Ascophyllum, Eisenia, Ectocarpus, Sargassum, Macrocystis, Amphiroa, umritarino Porphyra genus, Ceramium genus, Rhodoglossum genus, Iridia genus, Gracilia genus, Pterocladia genus, Acanthopalis genus Rhodymenia), Callophyllis Genus, Becherella, Gloiopeltis, Gelidium, Halymeria, Ahnfeltia, Campylaephora, and Dignea seaweed An oral hair-restoring agent containing an extract (E) tocotrienol, (F) a substance having an inhibitory action on 5α-reductase and / or (G) a cell activator is disclosed.

In JP-A-2003-40790 (Patent Document 2), a dry pulverized product of the stem of the plant and plant stevia and a dry pulverized product of the root of the plant and plant udo are sufficient in a ratio of 6 to 8: 4 to 2 by weight. A hair restorer characterized by using a steviado mixed concentrate obtained by stirring and mixing and then heating and concentrating to 2 to 5 times the equivalent amount of mineral water in a weight ratio of 10 to 15 times as a hair growth raw material. The steviado mixed concentrate is used as a hair restoration material for hair packs, soaps, hair shampoos or hair lotions.
The hair growth agent according to claim 1 or 2, wherein the steviado mixed concentrate is used as a hair lotion by mixing 5-30% and mineral water 95-70%. A hair restorer obtained by lactic acid fermentation of the steviaudo mixed concentrate and aging for 1 month or more. The mineral water is a hair restorer characterized in that it contains 50% or more of silicic acid and 10% or more of alumina. The dried pulverized material of the stem of the plant and plant Stevia and the dried pulverized material of the root of the plant and plant udo are well mixed at a weight ratio of 6 to 8: 4 to 2 and then mixed with mineral water at a weight ratio of 10 to 15 times. A method for producing a hair restorer comprising heating and concentrating to 2 to 5 times the equivalent amount to produce a steviaud mixed concentrate that is a hair growth raw material. A method for producing a hair restorer is disclosed, wherein the mineral water is water containing 50% or more of silicic acid and 10% or more of alumina.

Japanese Patent Application Laid-Open No. 2002-338489 (Patent Document 3) discloses an oral hair restorer comprising a combination of a volatile component obtained from seaweed and chlorophyll. An oral hair restorer consisting of a combination of nori and chlorophyll. An oral hair restorer consisting of a combination of volatile components distilled from one of red algae, brown algae and green algae and chlorophyll. An oral hair restorer consisting of a combination of chlorophyll and a mixture of volatile components distilled from several types of red algae, brown algae and green algae. Oral hair restorer containing roasted fragrance. An oral hair restorer with grilled seaweed. An oral hair restorer containing nutrients and palatinose. An oral hair restorer comprising a volatile component distilled from seaweed is disclosed.

Japanese Patent Application Laid-Open No. 2002-29935 (Patent Document 4) includes Altea, Yokuinin, Ivy, Arnica, Odorikosou, cornflower, linden, clematis, seaweed, clara, silk, ash and carrot oil, pyrrolidone, pyrrolidone A hair restorer containing one or more selected from the group consisting of carboxylic acid or a salt thereof, urea, L-arginine and L-aspartic acid and minoxidil. Altea, Yokuinin, Ivy, Arnica, Odorikosou, cornflower, linden, clematis, seaweed, clara, silk, gypsum and extract of chamomile, chamomile oil, pyrrolidone carboxylic acid or salt thereof, L-arginine and L-aspartic acid A hair restorer having a blending amount of 0.01 to 3%. The hair restorer whose urea compounding amount is 5 to 20%. A hair restorer obtained by extracting an extract with one or more solvents selected from the group consisting of ethanol, 1,3-butylene glycol, propylene glycol and purified water. A hair restorer containing 1 to 5% of minoxidil. A hair restorer containing ethanol and water is disclosed.

JP-A-2001-342145 (Patent Document 5) contains an extract of seaweeds belonging to green algae as an active ingredient, for external or internal hair growth. The external or internal hair restorer according to claim 1, wherein the seaweed is at least one selected from human rush (Monostroma nitidum), Aonori (Enteromorpha sp.), And Anaanaosa (Ulva pertusa). An ulcer healing agent for external or internal use, comprising an extract of seaweed belonging to green algae as an active ingredient. An external or internal ulcer healing agent is disclosed in which the seaweed is at least one selected from human exotherm (Monostroma nitidum), Aonori (Enteromorpha sp.), And Anaaosa (Ulva pertusa).

In Japanese Patent Laid-Open No. 11-21213 (Patent Document 6), the blood vessels in the head are enlarged to prevent the blood flow from being obstructed by removing the assembly or gentian, which has a high hair-growth effect, and the constriction of the blood flow. A hair restorer comprising a peony that is compatible with the above-mentioned assembly or gentiana in a refreshing cool blood drug. A warm spleen that warms the spleen and warms the heart and passes through the blood vessels. A hair restorer that contains any of the caricatures, jaundice, and licorice, a respirator that replenishes imagination and strengthens the splenic stomach. A hair-growth agent that contains the active blood removal medicine Tansan. The hair-restoring agent according to claim 1, which is blended with a hot-cold ginger, an active blood-deprived medicine, Kyukyu, Momojin, a respirator ginseng, and licorice. A hair-growth agent that contains ginger and hot springs of hot-cold medicine, Kawakyu of active blood removal medicine, Taojin and Dansang, carrots of aerating medicine, and Katsura branch of anti-tablet medicine.

Japanese Patent Application Laid-Open No. 10-194936 (Patent Document 7) discloses Impentence.
balsamine L. A hair restorer characterized by comprising an alcoholic extract solution of A hair-growth agent characterized by drinking an alcoholic extract of Impatience balsamine L. as an active ingredient. The narcissus flower alcohol extract is disclosed as a hair-growth agent comprising 20 to 50 parts by weight of the whole essence of the narcissus flower and 100% by weight of the aqueous solution containing ethyl alcohol at 10 ° C. or more. .

Japanese Patent No. 2648618 (Patent Document 8) includes ginseng (carrot), black bean (brown bean), sardine bird (kash), prosthetic fat (boiled), toki (branch), chicken blood wisteria (keiketto), senkyu Soaked in a 75% (V / V) ethanol with a herbal mixture containing dansins (tanjin), safflower (kouca), peach seeds (tonin), windbreak (bowfu), beetle roots (sea turmeric), and side leaf leaves A hair restoration agent containing a hair-growth active ingredient containing a hair-growth active ingredient mixed and adjusted with an extract obtained by leaving for 3 weeks at a cold temperature of about 10 ° C to 10 ° C and a solution obtained by extracting for 10 hours at a high temperature of about 75 ° C is disclosed. Yes.

JP 2000-159788 (Patent Document 9) contains trehalose containing trehalose and one or more ingredients selected from raw materials and processed intermediates for foods, pharmaceuticals, cosmetics, and industrial chemicals. Composition. Extracts are yeast extract, propolis extract, ginseng extract, turtle extract, vegetable extract, oyster extract, bonito extract, meat extract, kelp extract, chicken extract, beef extract, mushroom extract, licorice extract, stevia extract, chlorella extract, aloe extract And a trehalose-containing composition that is one or more selected from these enzyme-treated products. Trehalose-containing compositions can be used in foods, pharmaceuticals, cosmetics, industrial chemicals, fatigue relieving agents, tonics and tonics, hair restorers, preservatives, flavoring agents, emulsifiers, dressings, coloring agents, extenders, stabilizers, Forming agent, carrier, taste improver, quality improver, preservative, dehydrating agent, body imparting agent, shine imparting agent, viscosity imparting agent, water retention agent, edible desiccant, microbial contamination inhibitor, starch anti-aging agent Alternatively, a trehalose-containing composition, which is an agent for preventing alteration / deterioration due to hydrolysis, rancidity, browning or browning reaction, is disclosed.

Japanese Patent Laid-Open No. 2002-322073 (Patent Document 10) uses a single item or many items among many foods such as seaweed and vegetables that are rich in zinc and in a dry state, and combines them with water. Put it in a boiling pot and boil it well. Put the extracted liquid in the hot water and stir it, then take a bath in it and add a lot of zinc to the scalp and other whole body subcutaneous tissues. There has been disclosed a hair growth agent that permeates the extract containing it to prevent hair loss. In addition, you may add a preservative and a fragrance | flavor to this agent. Also add agarisk (preferably dried).

In JP 2002-238495 A (Patent Document 11), at least one type of hair-growth / hair removal preventing hair-growth granule is added to coral agaric mushroom granules, and a readily soluble container such as a capsule or wafer bag. Hair nourishing food intended for hair growth, hair loss prevention, etc. At least one kind of hair-growth and dry hair-restoring material is added to the dried granule of the coral spruce mushroom, and it is intended to prevent hair growth, hair loss, etc. filled in easily soluble containers such as capsules and wafer bags. Hair nourishing food.
The above-mentioned hair nourishing material uses a bamboo shoot that consists of one or a combination of several kinds of materials such as bean mushrooms, shimeji mushrooms, shiitake mushrooms, maitake mushrooms, cinnamon bark, ginger leaves, ginger, ginseng, assembly, root kelp, peppermint, walnuts, etc. A hair nourishing food intended for hair growth, hair loss prevention and the like is disclosed.

JP-A-2001-139430 (Patent Document 12) discloses a hair growth / hair nourishing composition comprising a solvent extract of Agaricus mycelia and / or a solvent extract of Kanrenboku as an active ingredient. Yes.

As described above, various kinds of hair growth have already been studied for their effects. However, it is also true that no one can yet feel the decisive effect.
JP 2003-160486 A JP 2003-40790 A JP 2002-338489 A JP 2002-29935 A JP 2001-342145 A Japanese Patent Laid-Open No. 11-21213 JP-A-10-194936 No. 2648618 JP 2000-159788 A JP 2002-322073 A JP 2002-238495 A JP 2001-139430 A

  The subject of this invention is providing the cosmetics for hair-restoration with a high effect.

The inventors of the present invention have focused on the nutritional components of plankton, of which zooplankton, especially krill. Phytoplankton varies from primitive algae that are less than 1 micron (thousandth of a millimeter) to large diatoms that are over 1 mm. On the other hand, zooplankton comes in various shapes and sizes, and you eat phytoplankton in a way that suits your life. Crustacean krills (several centimeters) and copepods (several millimeters) are eaten by rubbing and catching large algae (tens to hundreds of microns) using the legs around the mouth. Very small zooplankton (tens to hundreds of microns) like protozoa feed on even smaller algae and bacteria. Others, such as the Otamaboya, eat only small plankton using a special sieve to sort food.

There are currently 85 types of krill classified around the world. “Kiki” in “krill” means “offshore” and is widely distributed from the coast of the ocean to the offshore waters. The krill belongs to the crustacean upper class, the soft crustacean, the true soft shell subclass, the king shrimp, the krill, and the appearance is similar to the mysids and shrimps, Different animal groups. Krills, like other crustaceans, become adults after undergoing a molting stage that undergoes molting and different shapes. First, eggs are laid and hatched to become Nauplius larvae.

This nauplius larva has 1st and 2nd stages, and then becomes metanapurius larvae. Methanopius larvae molt and become shrimp-type calyptopis larvae. The calyptopis larvae period consists of three stages. During this period, the body is basically divided into two parts, the mouth organs are completed and food can be taken. The following Farsi larvae are in six stages, during which the abdominal legs and chest legs develop, spiders appear, and the development of light emitters, tail joints, and compound eyes are also seen. When juvenile is complete, all legs are completed, the tail is clear, and the figure is an adult. However, the gonad is underdeveloped, no secondary sexual characteristics are seen, and male and female discrimination is difficult. In the case of Antarctic krill, the eggs that have been laid down on the surface layer will sink, and the stage until hatching will proceed, and will hatch at a depth of several thousand meters. As hatched nauplius larvae, metanoprius larvae, and as the stage of development progresses, they gradually rise to the upper layers, and calyptopis larvae that can feed, phytoplankton, etc. It will come to near the surface where there is. When eggs arrive on the continental shelf, etc., at a depth of about 500 meters, the eggs are growing on the spot, and the larvae are growing near the bottom of the continental shelf and hatched at a depth of several thousand meters. As with, it rises near the surface when it can be eaten.

  In general, krills feed on phytoplankton during the larval stage. Juvenile and adults are slightly different depending on the type and habitat, but feeding on the chest leg is fundamental. The most common feeding method is filtered feeding. This is a method of spreading chest legs and filtering phytoplankton and small zooplankton in seawater. There is also a method of catching and eating medium-sized zooplankton using the chest legs. There are various feeding patterns, such as scraping phytoplankton under the ice using the chest legs, catching organisms in the mud, and feeding detritus in the sea.

In this way, krills eat phytoplankton, and the krill feeds fish and the like, and there are abundant nutrients inside the living body. In other words, zooplankton containing EPA (and DHA) is eaten by zooplankton, small fish such as sardine feed on it, and large migratory fish such as tuna eat sardine and so on. The main action of EPA is to prevent blood coagulation, improve blood flow (blood smoothing effect), reduce bad cholesterol, and increase good cholesterol. Effective in preventing and improving lifestyle-related diseases such as sclerosis, myocardial infarction, cerebral infarction, hyperlipidemia, hypertension, obesity, etc. Prevents blood coagulation and improves blood flow (blood smoothing effect) ・ It is one of the ingredients that prevent oxidation even if bad cholesterol is reduced and good cholesterol is increased. EPA and DHA have many excellent actions, including the “blood smooth effect”, but they also have weaknesses. Properties: Oxidized EPA and DHA increase the active oxygen in the body, so it works negatively for the body, so the combination with vitamin E and vitamin C, which are powerful antioxidants, is desired.

  Furthermore, the present inventor has paid attention to the synergistic action of zooplankton extract, seaweed extract, stevia and udo mixture extract, and agaricus koji extract, and tried to make cosmetics containing these extracts. It was.

  It is possible to provide a hair-growth cosmetic that exhibits a remarkable effect without side effects.

  The gist of the present invention is as follows. (1) A hair-growth cosmetic comprising one or more of zooplankton extract, seaweed extract, stevia and udon extract, and agaricus koji extract. (2) Cosmetics characterized by using daphnia as zooplankton and a mixture of Monoostroma nitidum, Enteromorpha sp. And Anavaosa (Ulva pertusa) as seaweed.

  EXAMPLES The present invention will be described below with reference to examples, but the present invention is not limited to the examples.

[Production method of krill extract, zooplankton]
The method for producing the zooplankton (krill) extract can be performed using either hot water or an organic solvent. In this example, the following procedure was performed. 100 g of dry pulverized product of krill is put in 1 L of 60 ° C. 50% ethanol, extracted for one day and night, and after centrifugation, it is separated into the extract and the residue. The residue is again heated by about 5 times the amount of 100 ° C. heat. Extraction is performed day and night by adding water, followed by centrifugation, and a mixture of the extract extracted at 60 ° C. and the extract extracted at 100 ° C. is used as a krill extract. Concentration gave 10 g of extract (krill extract).

[Method of producing seaweed extract]
Seaweed extract (in the present invention, human exoma (Monostroma
nitidum), Aonori (Enteromorphasp.) and Anaaosa (Ulva pertusa) were selected. ) Extraction method is not particularly limited, and for example, it may be a heat extraction or a room temperature extraction. Examples of the solvent to be extracted include water, lower monohydric alcohols (methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, etc.), liquid polyhydric alcohols (1,3-butylene glycol, Propylene glycol, glycerin, etc.), ketones (acetone, methyl ethyl ketone, etc.), acetonitrile, esters (ethyl acetate, butyl acetate, etc.), hydrocarbons (hexane, heptane, liquid paraffin, etc.), ethers (ethyl ether, propyl ether) Etc.). These solvents may be used alone or in combination of two or more. A solvent selected from water, ethanol, 1,3-butylene glycol, and propylene glycol is preferably used. Further, supercritical extraction using carbon dioxide or the like can be used. The extract may be used as it is, or may be used after concentration, dilution, filtration or the like, if necessary. Further, the extracted solution may be subjected to a treatment such as concentration to dryness, spray drying, freeze drying, etc., and used as a dried product. In this example, extraction was performed by the following method. 1 L of purified water was added to 100 g of a mixed dried product of Monoostroma nitidum, Enteromorphasp. And Ulva pertusa and extracted for 2 hours at 95-100 ° C. The obtained extract was cooled and filtered. Concentration under reduced pressure yielded 10 g of extract (Monostroma nitidum, Aonori (Enteromorpha sp.) And Anaaaosa (Ulva pertusa extract).

[Production method of stevia and udo mixture extract]
Stems of plant stevia are dried and ground to obtain 100 g of dry powder. Similarly, the roots of the plant udder are dried and ground to obtain 100 g of a dry powder. Stir and mix Stevia dry powder and Udo dry powder well. This mixed powder is put into mineral water having a weight ratio of 10 times, and heated and concentrated to 2 to 5 times the equivalent amount to obtain a steviado mixed concentrate. The mineral water used here is mineral water obtained by bringing tap water or well water into contact with a rock containing 50% or more of silicic acid and 10% or more of alumina for 24 hours or more. Stevia and Udo mixture is lactic acid fermented and matured for over 1 month to complete the extract. The extract was filtered and concentrated under reduced pressure to 10 g. For the extract mineral water, rock extracted from Mt. Iokawa, Ishikawa Prefecture was used. Mineral water was prepared by forced circulation of 30 liters of well water for 24 hours to 1 kg of Ioyama rock quarried to a diameter of 10 mm to 20 mm (stevia and udo extract).

[Method for producing Agaricus mushroom extract]
In the case of agaricus mycelium, the agaricus mycelium cultured in a wheat grain medium or the like is dried and immersed in the solution for 0.1 to 144 hours. Next, a method for obtaining an extract by filtering the obtained solution after immersion in a solvent, a method for obtaining an extract solid by removing the solvent from the extract under reduced pressure, and further, adsorbing and molecular sieve the extracted solid. And a method for obtaining a purified extract purified to a high concentration by a purification step such as centrifugation, ion exchange, various types of chromatography, or a combination thereof. In the case of Kanrenboku, a dried product at a desired site such as a bark of Kanrenboku or a pulverized product thereof is immersed in a solvent for 0.1 to 144 hours. Next, a method for obtaining an extract by filtering the obtained solution after immersion in a solvent, a method for obtaining an extract solid by removing the solvent from the extract under reduced pressure, and further, adsorbing and molecular sieve the extracted solid. And a method for obtaining a purified extract purified to a high concentration by a purification step such as centrifugation, ion exchange, various types of chromatography, or a combination thereof. Examples of the solvent used for the extraction include monovalent alcohols having 1 to 22 carbon atoms such as methanol, ethanol, propanol, isopropanol, n-butanol, lauryl alcohol, cetanol, stearyl alcohol, oleyl alcohol, and behenyl alcohol, and side chains. Monohydric alcohol having; glycols such as propylene alcohol, 1,3-butylene glycol and polyethylene glycol; trivalent alcohols such as glycerin, diglycerin and triglycerin; ketones such as acetone and methyl ethyl ketone; ethyl acetate and fatty acid Examples include various esters such as ethyl ester; various polar organic solvents such as aromatic hydrocarbons such as toluene, nonpolar organic solvents, water, and the like. In use, these can be used alone or as a mixture. These solvents can be used by melting by heating or adjusting the pH as necessary.

  In this example, 100 g of dry powder of agaricus was dipped in 50% etarule of 10 times the amount of 60 ° C. for 2 days, and the extract was filtered and concentrated under reduced pressure to obtain 10 g of extract (Agaricus koji). extract)

[Adjustment of cosmetics]
Artnics were prepared for the following types of hair growth. Numbers are% by weight.

Hair Nick A
1. Krill extract ... 1.0
2. Seaweed extract ... 1.0
3. Stevia and Udo extract ... 1.0
4). Agaricus mushroom extract ... 1.0
5. Propylene glycol ... 5.0
6). Sodium hyaluronate ... 0.01
7). Vitamin C ... 0.02
8.75% ethanol remaining

Hair Nick B
1. Krill extract ... 4.0
2. Seaweed extract ... 0
3. Stevia and Udo extract ... 0
4). Agaricus mushroom extract ... 0
5. Propylene glycol ... 5.0
6). Sodium hyaluronate ... 0.01
7). Vitamin C ... 0.02
8.75% ethanol remaining

Hair Nick C
1. Krill extract 2.0
2. Seaweed extract ... 2.0
3. Stevia and Udo extract ... 0
4). Agaricus mushroom extract ... 0
5. Propylene glycol ... 5.0
6). Sodium hyaluronate ... 0.01
7). Vitamin C ... 0.02
8.75% ethanol remaining

Hair Nick D
1. Krill extract 2.0
2. Seaweed extract ... 0
3. Stevia and Udo Extract ... 2.0
4). Agaricus mushroom extract ... 0
5. Propylene glycol ... 5.0
6). Sodium hyaluronate ... 0.01
7). Vitamin C ... 0.02
8.75% ethanol remaining

Hair Nick E
1. Krill extract 2.0
2. Seaweed extract ... 0
3. Stevia and Udo extract ... 0
4). Agaricus mushroom extract ... 2.0
5. Propylene glycol ... 5.0
6). Sodium hyaluronate ... 0.01
7). Vitamin C ... 0.02
8.75% ethanol remaining

Hair Nick F
1. Krill extract ... 0
2. Seaweed extract ... 4.0
3. Stevia and Udo extract ... 0
4). Agaricus mushroom extract ... 2.0
5. Propylene glycol ... 5.0
6). Sodium hyaluronate ... 0.01
7). Vitamin C ... 0.02
8.75% ethanol remaining

Hair Nick G
1. Krill extract ... 0
2. Seaweed extract ... 0
3. Stevia and Udo extract 4.0
4). Agaricus mushroom extract ... 0
5. Propylene glycol ... 5.0
6). Sodium hyaluronate ... 0.01
7). Vitamin C ... 0.02
8.75% ethanol remaining

Hair Nick H
1. Krill extract ... 0
2. Seaweed extract ... 0
3. Stevia and Udo extract ... 0
4). Agaricus mushroom extract ... 4.0
5. Propylene glycol ... 5.0
6). Sodium hyaluronate ... 0.01
7). Vitamin C ... 0.02
8.75% ethanol remaining

Hair Nick I
1. Krill extract ... 0
2. Seaweed extract ... 0
3. Stevia and Udo extract ... 0
4). Agaricus mushroom extract ... 0
5. Propylene glycol ... 5.0
6). Sodium hyaluronate ... 0.01
7). Vitamin C ... 0.02
8.75% ethanol remaining

An evaluation experiment was conducted to confirm the effect of the hair restorer according to the present invention. Ten men with bald heads were selected as panels. Everybody used hair artnics every morning as follows to evaluate the situation after 3 months. Wash head thoroughly with normal shampoo or soap. After washing, the hair growth hair artnic was sprinkled with 2 ml once a day.

These results are based on the results of the determination method.
The criteria for the hair loss prevention test were as follows.
X means no improvement despite treatment.
○ indicates that hair loss progressed slightly.
◎ means that hair loss has stopped.

Table 1 Evaluation result table Panel ab c de f gh i j
Hair art A ◎ ◎ ○ ◎ ◎ ◎ ○ ◎ ◎ ◎
Hair art B ◎ ○ ◎ ○ ◎ ○ ○ ◎ ○ ○

Hair artic C ◎ ◎ ○ ◎ ○ ◎ ○ ◎ ○ ○
Hair art D ○ ○ ◎ ○ ◎ ◎ ○ ○ ○ ○ ○
Hair artic E ○ ○ ◎ ○ ○ ◎ ○ ◎ ○ ◎

Hair art F ○ ○ ○ ◎ ○ ○ ○ ○ ○ ◎
Hair and Nick G ○ ○ ○ ◎ ○ ○ ◎ ○ ○ ○
Hair art H ◎ ◎ ○ ○ ○ ○ ○ ○ ○ ○

Hair Nick K × × × × × × × × × ×

<Results> Although the zooplankton extract, the seaweed extract, the stevia / udo mixture extract, and the agaricus koji extract were used in combination, the hair tonic hair-growth effect was the greatest.

When the hair restorer of the present invention is used as a hair restorer for external use, it can be used in various forms such as lotions, emulsions, gels, aerosols, creams, ointments, powders and the like. Moreover, it can be used by adding to various hair cosmetics such as hair lotion, hair milk, hair mist, hair cream, hair gel, hair foam, hair shampoo, hair rinse, hair treatment and the like.

The hair growth cosmetics of the present invention include solvents, solubilizers, greasing agents, emulsifiers, chelating agents, pH adjusters, fragrances, ultraviolet absorbers, preservatives used as basic components in normal hair cosmetics and the like. Etc. can be blended. For example, as the solvent, water (purified water), ethanol, n-propanol, isopropanol, or a mixture thereof can be used, but an organic solvent is used in order to prevent unnecessary irritation to the skin. Is preferably diluted with water.

Moreover, in order to enhance the hair-growth effect, the hair-growth cosmetic composition of the present invention may contain other compounds that are expected to have a hair-growth promoting effect, if necessary. Examples of such compounds include vitamins (retinol, retinal, vitamin A1 acid, vitamin A1 acid ester, acetate retinol, retinol palmitate, α-carotene, β-carotene, γ-carotene, lycopene, thiamine nitrate, thiamine. Hydrochloride, thiamine disulfide compound, riboflavin, flavin nucleotide, flavin tetrabutyrate, riboflavin tetranicotinate, pyridoxine hydrochloride, pyridoxal hydrochloride, pyridoxamine hydrochloride, cyanocobalamin, nicotinic acid, nicotinamide, pantothenic acid, pantothenate, pantothenyl alcohol , Pantothenyl ethyl ether, biotin, ascorbic acid, ascorbate, ascorbate, vitamin Ds, tocopherol, tocopherol acetate, ubiquitous , Plastoquinone, vitamin K, etc.), choline, essential fatty acids (linoleic acid, linolenic acid, arachidonic acid), eicosatrienoic acid, female hormone, corticosteroid, antihypertensive agent (minoxidil, diazoxide, etc.), TCA circuit Related substances (c-AMP, succinic acid, citric acid, ATP, FAD, NAD, NADP, L-malic acid, methylmalonyl CoA, fumaric acid, succinyl CoA, coenzyme A, GDP, GTP, ADP, AMP, oxaloacetic acid, Acetyl CoA, etc.), plant extracts (hinokitiol, clove extract, aloe extract, licorice extract, salamander extract, red gecko extract, assembly extract, hop extract, rosemary extract, sage extract, thyme Extracts, carrot extracts, etc.) and synthetic medicinal ingredients (capronium chloride) Etc.) and the like.

Claims (2)

  A hair-growth cosmetic composition comprising any one or more of an zooplankton extract, a seaweed extract, a stevia and udon mixture extract, and an agaricus koji extract. The hair-growth cosmetic composition according to claim 1, wherein a mixture of krill is used as the zooplankton, and a mixture of human easter (Monostroma nitidum), aonori (Enteromorpha sp.) And anaaosa (Ulva pertusa) is used as the seaweed.