JP2005539067A - ポリエチレングリコールリンカーを用いる二重特異性分子の産生 - Google Patents
ポリエチレングリコールリンカーを用いる二重特異性分子の産生 Download PDFInfo
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41173102P | 2002-09-16 | 2002-09-16 | |
| PCT/US2003/029059 WO2004024889A2 (en) | 2002-09-16 | 2003-09-16 | Production of bispecific molecules using polyethylene glycol linkers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005539067A true JP2005539067A (ja) | 2005-12-22 |
| JP2005539067A5 JP2005539067A5 (enExample) | 2006-11-02 |
Family
ID=31994266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004536556A Withdrawn JP2005539067A (ja) | 2002-09-16 | 2003-09-16 | ポリエチレングリコールリンカーを用いる二重特異性分子の産生 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060153839A1 (enExample) |
| EP (1) | EP1539811A4 (enExample) |
| JP (1) | JP2005539067A (enExample) |
| AU (1) | AU2003270686A1 (enExample) |
| CA (1) | CA2499075A1 (enExample) |
| WO (1) | WO2004024889A2 (enExample) |
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|---|---|---|---|---|
| JP2014516991A (ja) * | 2011-06-03 | 2014-07-17 | スリーエム イノベイティブ プロパティズ カンパニー | ポリエチレングリコールセグメントを有するヘテロ２官能性リンカー及び該リンカーから調製された免疫反応調節複合体 |
| JP2017160219A (ja) * | 2011-06-03 | 2017-09-14 | スリーエム イノベイティブ プロパティズ カンパニー | ヒドラジノ１ｈ−イミダゾキノリン−４−アミン及びこれから調製された複合体 |
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| US20060147457A1 (en) * | 2002-05-13 | 2006-07-06 | Porter James P | Purified composition of bispecific molecules and methods of production |
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| WO2004087759A2 (en) * | 2003-03-28 | 2004-10-14 | Elusys Therapeutics, Inc. | Method and compositions for conversion of antibody activity |
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| US6572856B1 (en) * | 1998-09-10 | 2003-06-03 | The University Of Virginia Patent Foundation | Methods for the prevention and treatment of cancer using anti-C3b(i) antibodies |
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| WO2002046208A2 (en) * | 2000-11-01 | 2002-06-13 | Elusys Therapeutics, Inc. | Method of producing biospecific molecules by protein trans-splicing |
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| US20040018203A1 (en) * | 2001-06-08 | 2004-01-29 | Ira Pastan | Pegylation of linkers improves antitumor activity and reduces toxicity of immunoconjugates |
| WO2003049684A2 (en) * | 2001-12-07 | 2003-06-19 | Centocor, Inc. | Pseudo-antibody constructs |
-
2003
- 2003-09-16 JP JP2004536556A patent/JP2005539067A/ja not_active Withdrawn
- 2003-09-16 US US10/527,936 patent/US20060153839A1/en not_active Abandoned
- 2003-09-16 AU AU2003270686A patent/AU2003270686A1/en not_active Abandoned
- 2003-09-16 WO PCT/US2003/029059 patent/WO2004024889A2/en not_active Ceased
- 2003-09-16 EP EP03752394A patent/EP1539811A4/en not_active Withdrawn
- 2003-09-16 CA CA002499075A patent/CA2499075A1/en not_active Abandoned
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014516991A (ja) * | 2011-06-03 | 2014-07-17 | スリーエム イノベイティブ プロパティズ カンパニー | ポリエチレングリコールセグメントを有するヘテロ２官能性リンカー及び該リンカーから調製された免疫反応調節複合体 |
| JP2017160219A (ja) * | 2011-06-03 | 2017-09-14 | スリーエム イノベイティブ プロパティズ カンパニー | ヒドラジノ１ｈ−イミダゾキノリン−４−アミン及びこれから調製された複合体 |
| JP2017160220A (ja) * | 2011-06-03 | 2017-09-14 | スリーエム イノベイティブ プロパティズ カンパニー | ポリエチレングリコールセグメントを有するヘテロ２官能性リンカー及び該リンカーから調製された免疫反応調節複合体 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1539811A4 (en) | 2006-05-24 |
| EP1539811A2 (en) | 2005-06-15 |
| US20060153839A1 (en) | 2006-07-13 |
| WO2004024889A2 (en) | 2004-03-25 |
| WO2004024889A3 (en) | 2004-07-29 |
| CA2499075A1 (en) | 2004-03-25 |
| AU2003270686A1 (en) | 2004-04-30 |
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