JP2005537300A - キナーゼ阻害剤としての二環式複素芳香族化合物 - Google Patents

キナーゼ阻害剤としての二環式複素芳香族化合物 Download PDF

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JP2005537300A
JP2005537300A JP2004527055A JP2004527055A JP2005537300A JP 2005537300 A JP2005537300 A JP 2005537300A JP 2004527055 A JP2004527055 A JP 2004527055A JP 2004527055 A JP2004527055 A JP 2004527055A JP 2005537300 A JP2005537300 A JP 2005537300A
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ブルッキングス、ダニエル、クリストファー
デーヴィス、ジェレミー、マーティン
ランガム、バリー、ジョン
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セルテック アール アンド ディ リミテッド
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    • C07—ORGANIC CHEMISTRY
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    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
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  • Diabetes (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
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JP2004527055A 2002-08-13 2003-08-11 キナーゼ阻害剤としての二環式複素芳香族化合物 Pending JP2005537300A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0218800.1A GB0218800D0 (en) 2002-08-13 2002-08-13 Chemical compounds
PCT/GB2003/003501 WO2004014920A1 (en) 2002-08-13 2003-08-11 Bicyclic heteroaromatic compounds as kinase inhibitors

Publications (2)

Publication Number Publication Date
JP2005537300A true JP2005537300A (ja) 2005-12-08
JP2005537300A5 JP2005537300A5 (https=) 2006-09-14

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JP2004527055A Pending JP2005537300A (ja) 2002-08-13 2003-08-11 キナーゼ阻害剤としての二環式複素芳香族化合物

Country Status (7)

Country Link
US (1) US7592455B2 (https=)
EP (1) EP1539769A1 (https=)
JP (1) JP2005537300A (https=)
AU (1) AU2003252990B2 (https=)
CA (1) CA2495518A1 (https=)
GB (1) GB0218800D0 (https=)
WO (1) WO2004014920A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005530838A (ja) * 2002-06-20 2005-10-13 セルテック アール アンド ディ リミテッド Ｐ３８キナーゼインヒビターとしてのアリールアミン置換二環式ヘテロ芳香族化合物
JP2010513370A (ja) * 2006-12-19 2010-04-30 エフ．ホフマン−ラ ロシュ アーゲー ピラゾロ［３，４−ｄ］ピリミジンｐ３８ＭＡＰキナーゼインヒビター

Families Citing this family (35)

* Cited by examiner, † Cited by third party
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GB0222743D0 (en) * 2002-10-01 2002-11-06 Celltech R&D Ltd Chemical compounds
CA2528603A1 (en) * 2003-06-20 2004-12-29 Celltech R & D Limited Thienopyridone derivatives as kinase inhibitors
US7482452B2 (en) 2003-06-20 2009-01-27 Celltech R&D Limited Process for preparing 3-aminothienopyridone derivatives
CA2528602A1 (en) * 2003-06-20 2004-12-29 Celltech R & D Limited Thienopyridone derivatives as kinase inhibitors
JP2007509123A (ja) * 2003-10-24 2007-04-12 セルテック アール アンド ディ リミテッド キナーゼ阻害剤としてのチエノ−ピリジノン誘導体
WO2007059219A1 (en) 2005-11-15 2007-05-24 Vertex Pharmaceuticals Incorporated Azaindazoles useful as inhibitors of kinases
AR059898A1 (es) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
EP1992344A1 (en) 2007-05-18 2008-11-19 Institut Curie P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
SI2203439T1 (sl) 2007-09-14 2011-05-31 Ortho Mcneil Janssen Pharm 1',3'-disubstituirani 4-fenil-3,4,5,6-tetrahidro-2H-1'H-(1,4')bipiridinil-2'-oni
PL2200985T3 (pl) 2007-09-14 2011-12-30 Ortho Mcneil Janssen Pharmaceuticals Inc 1,3-Dipodstawione-4-(arylo-X-fenylo)-1H-pirydyn-2-ony
CN101801930B (zh) 2007-09-14 2013-01-30 奥梅-杨森制药有限公司 1,3-二取代的-4-苯基-1h-吡啶-2-酮
CN101861316B (zh) 2007-11-14 2013-08-21 奥梅-杨森制药有限公司 咪唑并[1,2-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
EP2344470B1 (en) 2008-09-02 2013-11-06 Janssen Pharmaceuticals, Inc. 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
WO2010043396A1 (en) 2008-10-16 2010-04-22 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
JP5690277B2 (ja) 2008-11-28 2015-03-25 ジャンセン ファーマシューティカルズ， インコーポレイテッド． 代謝型グルタミン酸受容体の調節因子としてのインドールおよびベンゾオキサジン誘導体
CN102439008B (zh) 2009-05-12 2015-04-29 杨森制药有限公司 1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途
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