JP2005536507A5 - - Google Patents
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- Publication number
- JP2005536507A5 JP2005536507A5 JP2004521592A JP2004521592A JP2005536507A5 JP 2005536507 A5 JP2005536507 A5 JP 2005536507A5 JP 2004521592 A JP2004521592 A JP 2004521592A JP 2004521592 A JP2004521592 A JP 2004521592A JP 2005536507 A5 JP2005536507 A5 JP 2005536507A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pyrrolo
- compound
- pyridazine
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39473402P | 2002-07-11 | 2002-07-11 | |
| PCT/US2003/021493 WO2004006836A2 (en) | 2002-07-11 | 2003-07-08 | Treatment of neuropathic pain with 6h-pyrrolo[3,4-d]pyridazine compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005536507A JP2005536507A (ja) | 2005-12-02 |
| JP2005536507A5 true JP2005536507A5 (https=) | 2006-04-20 |
Family
ID=30115760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004521592A Pending JP2005536507A (ja) | 2002-07-11 | 2003-07-08 | ６Ｈ−ピロロ［３，４−ｄ］ピリダジン化合物による神経障害性疼痛の治療 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7465730B2 (https=) |
| EP (1) | EP1539168A2 (https=) |
| JP (1) | JP2005536507A (https=) |
| AU (1) | AU2003248907B2 (https=) |
| CA (1) | CA2492022A1 (https=) |
| WO (1) | WO2004006836A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY28538A1 (es) | 2003-09-26 | 2005-04-29 | Vertex Pharma | Derivados de fenil-piperazina como moduladores de receptores muscarínicos |
| GB0405200D0 (en) * | 2004-03-08 | 2004-04-21 | Pfizer Ltd | Combinations comprising alpha-2-delta ligands |
| KR20080064956A (ko) | 2005-09-27 | 2008-07-10 | 미리어드 제네틱스, 인크. | 치료학적 화합물로서의 피롤 유도체 |
| CN101003537A (zh) * | 2006-01-17 | 2007-07-25 | 上海恒瑞医药有限公司 | 吡咯并哒嗪类衍生物及其制备方法和用途 |
| TW200914457A (en) | 2007-05-31 | 2009-04-01 | Kyowa Hakko Kogyo Kk | Pyrimidodiazepinone derivative |
| BRPI0818193B8 (pt) | 2007-09-28 | 2021-05-25 | Daiichi Sankyo Co Ltd | composto, composição farmacêutica, e, uso de um composto |
| CN101970427A (zh) | 2008-02-29 | 2011-02-09 | Vm生物医药公司 | 治疗疼痛症状及其它失调的方法 |
| EP2313102A2 (en) * | 2008-07-03 | 2011-04-27 | Biota Scientific Management | Bycyclic nucleosides and nucleotides as therapeutic agents |
| GB0813144D0 (en) | 2008-07-17 | 2008-08-27 | Glaxo Group Ltd | Novel compounds |
| JP5557292B2 (ja) | 2009-03-26 | 2014-07-23 | 第一三共株式会社 | 二環性γ−アミノ酸誘導体の製造方法 |
| HUE035366T2 (en) | 2011-06-08 | 2018-05-02 | Daiichi Sankyo Co Ltd | A method for the preparation of a bicyclic compound by Claisen rearrangement |
| ES2659162T3 (es) | 2011-06-08 | 2018-03-14 | Daiichi Sankyo Company, Limited | Procedimiento de producción de compuesto bicíclico a través de una sal de iminio |
| KR101944575B1 (ko) | 2011-12-15 | 2019-04-17 | 다이이찌 산쿄 가부시키가이샤 | 부제 촉매를 사용하는 2고리형 화합물의 광학 분할 방법 |
| EP2837689B1 (en) | 2012-04-10 | 2017-02-15 | Daiichi Sankyo Company, Limited | Optical resolution method for bicyclic compound using enzyme |
| WO2014069626A1 (ja) * | 2012-11-01 | 2014-05-08 | 協和発酵キリン株式会社 | ピリミドジアゼピノン化合物の製造方法 |
| EP2928891B1 (en) | 2012-12-04 | 2019-02-20 | Rigel Pharmaceuticals, Inc. | Protein kinase c inhibitors and uses thereof |
| TWI635071B (zh) | 2013-07-08 | 2018-09-11 | 第一三共股份有限公司 | 光學活性二環γ－胺基酸衍生物及其製造方法 |
| WO2018100041A1 (en) * | 2016-11-30 | 2018-06-07 | Laboratorios Del Dr. Esteve, S.A. | Meta substituted phenylpyrazolo- and phenylpyrrolo- pyridazine derivatives having multimodal activity against pain |
| EP3548489A1 (en) * | 2016-11-30 | 2019-10-09 | Esteve Pharmaceuticals, S.A. | Ortho substituted phenylpyrazolo- and phenylpyrrolo-pyridazine derivatives having multimodal activity against pain |
| US20200062767A1 (en) * | 2017-05-30 | 2020-02-27 | Esteve Pharmaceuticals, S.A. | Substituted pyrrolidinyl and piperidinyl pyrazolopyridazine derivatives having multimodal activity against pain |
| GB202106872D0 (en) * | 2021-05-13 | 2021-06-30 | Addex Pharmaceuticals Sa | Novel compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622948A (en) * | 1994-12-01 | 1997-04-22 | Syntex (U.S.A.) Inc. | Pyrrole pyridazine and pyridazinone anti-inflammatory agents |
| GB9726701D0 (en) * | 1997-12-18 | 1998-02-18 | Merck Sharp & Dohme | Therapeutic use |
-
2003
- 2003-07-08 US US10/520,962 patent/US7465730B2/en not_active Expired - Fee Related
- 2003-07-08 CA CA002492022A patent/CA2492022A1/en not_active Abandoned
- 2003-07-08 WO PCT/US2003/021493 patent/WO2004006836A2/en not_active Ceased
- 2003-07-08 JP JP2004521592A patent/JP2005536507A/ja active Pending
- 2003-07-08 EP EP03764414A patent/EP1539168A2/en not_active Withdrawn
- 2003-07-08 AU AU2003248907A patent/AU2003248907B2/en not_active Ceased
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