JP2005534945A - 分子間相互作用の計測方法 - Google Patents
分子間相互作用の計測方法 Download PDFInfo
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- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
- G01J3/4406—Fluorescence spectrometry
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- G—PHYSICS
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- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/457—Correlation spectrometry, e.g. of the intensity
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- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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- G01N21/645—Specially adapted constructive features of fluorimeters
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- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
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- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
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| PCT/US2003/024780 WO2004013610A2 (en) | 2002-08-01 | 2003-08-01 | Method of measuring molecular interactions |
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| JP2005534945A true JP2005534945A (ja) | 2005-11-17 |
| JP2005534945A5 JP2005534945A5 (https=) | 2006-09-14 |
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| EP (2) | EP1527333A1 (https=) |
| JP (2) | JP2005534945A (https=) |
| AU (2) | AU2003259056B2 (https=) |
| CA (2) | CA2494478A1 (https=) |
| WO (2) | WO2004013610A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2009522541A (ja) * | 2005-12-29 | 2009-06-11 | ビーエーエスエフ ソシエタス・ヨーロピア | 媒体中で化学化合物の相同性及び非相同性ならびに濃度を決定する方法 |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DE10115309A1 (de) * | 2001-03-28 | 2002-10-02 | Gnothis Holding Sa Ecublens | Mikroskopanordnung zur Fluoreszenzspektorskopie, insbesondere Fluoreszenzkorrelationsspektroskopie |
| IL157206A0 (en) * | 2003-08-03 | 2004-02-19 | Correlating spatial position of chemical species on a substrate with molecular weight, structure and chemical reactivity | |
| JP4746276B2 (ja) * | 2004-02-25 | 2011-08-10 | オリンパス株式会社 | 膜構造を有する生体構造物の膜機能を解析する方法 |
| US20050191705A1 (en) * | 2004-03-01 | 2005-09-01 | Werner James H. | High throughput screening using fluorophore labeled lipid membranes and fluorescence correlation spectroscopy |
| WO2005089524A2 (en) * | 2004-03-19 | 2005-09-29 | U.S. Genomics, Inc. | Compositions and methods for detection of single molecules |
| FR2869412B1 (fr) * | 2004-04-27 | 2006-07-14 | Centre Nat Rech Scient Cnrse | Determination d'une fonction d'autocorrelation |
| JP4338590B2 (ja) | 2004-06-03 | 2009-10-07 | 独立行政法人科学技術振興機構 | 蛍光相関分光法による抗原の迅速検出及び／又は測定法。 |
| US7214927B2 (en) * | 2004-10-08 | 2007-05-08 | Avago Technologies Ecbu Ip (Singapore) Pte. Ltd. | Method and apparatus using liquid crystal light valve to filter incident light on a photodetector |
| EP1672353A1 (de) * | 2004-12-16 | 2006-06-21 | Evotec Technologies GmbH | Verfahren zur Zustandserfassung eines biologischen Systems mit einem Lumineszenzsensor |
| FR2890446B1 (fr) * | 2005-09-05 | 2008-04-18 | Cis Bio Internat Sa | Methode de detection d'interaction intracellulaire entre bio-molecules |
| JP5473202B2 (ja) * | 2006-10-13 | 2014-04-16 | 滋賀県 | 試料中の蛍光性物質を検出する方法およびシステム |
| US7916304B2 (en) * | 2006-12-21 | 2011-03-29 | Howard Hughes Medical Institute | Systems and methods for 3-dimensional interferometric microscopy |
| JP5401115B2 (ja) * | 2009-02-13 | 2014-01-29 | 興和株式会社 | 生物由来の生理活性物質の測定方法及び測定装置 |
| US20120135874A1 (en) * | 2009-05-08 | 2012-05-31 | The Johns Hopkins University | Single molecule spectroscopy for analysis of cell-free nucleic acid biomarkers |
| FR2949560A1 (fr) | 2009-09-02 | 2011-03-04 | Centre Nat Rech Scient | Systeme de spectroscopie a guide d'onde pour l'analyse de particules dans un milieu |
| WO2011123092A1 (en) * | 2010-03-29 | 2011-10-06 | Analogic Corporation | Optical detection system and/or method |
| US20130215426A1 (en) * | 2010-08-04 | 2013-08-22 | Nir Science Corporation | Method and apparatus for analyte detection |
| EP3358387A1 (en) * | 2010-08-27 | 2018-08-08 | The Board of Trustees of The Leland Stanford Junior University | Microscopy imaging device with advanced imaging properties |
| US20120184831A1 (en) * | 2011-01-18 | 2012-07-19 | Radiation Monitoring Devices, Inc. | Systems, devices and methods for monitoring hemodynamics |
| IL234766A (en) * | 2014-09-21 | 2015-09-24 | Visionsense Ltd | Fluorescent Imaging System |
| WO2017214730A1 (en) | 2016-06-14 | 2017-12-21 | Novadaq Technologies Inc. | Methods and systems for adaptive imaging for low light signal enhancement in medical visualization |
| EP4242743A3 (en) * | 2017-02-10 | 2023-10-18 | Stryker European Operations Limited | Open-field handheld fluorescence imaging systems and methods |
| CN109520982A (zh) * | 2018-11-20 | 2019-03-26 | 东南大学 | 一种荧光相关光谱测量系统 |
| CN113295662B (zh) * | 2021-05-21 | 2022-04-12 | 上海交通大学 | 一种用于三种分子间结合作用解析的荧光三元相关光谱系统 |
| EP4407295A4 (en) * | 2022-01-21 | 2025-10-15 | Horiba Ltd | PARTICLE ANALYSIS DEVICE |
| GB202203238D0 (en) * | 2022-03-09 | 2022-04-20 | Renishaw Plc | Optical apparatus |
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| JPH11326208A (ja) * | 1998-05-21 | 1999-11-26 | Bunshi Bio Photonics Kenkyusho:Kk | 解析方法および解析装置 |
| WO2001059436A2 (en) * | 2000-02-10 | 2001-08-16 | Evotec Oai Ag | Fluorescence intensity and lifetime distribution analysis |
| WO2002048693A1 (fr) * | 2000-12-14 | 2002-06-20 | Olympus Optical Co., Ltd. | Analyseur fluorometrique et analyse fluorometrique |
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| EP0537270B1 (en) * | 1990-07-02 | 1998-09-09 | The Regents Of The University Of California | Detection of analytes using fluorescent energy transfer |
| US5220172A (en) * | 1991-09-23 | 1993-06-15 | The Babcock & Wilcox Company | Fluorescence analyzer for lignin |
| US5674698A (en) * | 1992-09-14 | 1997-10-07 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
| US5445935A (en) * | 1992-11-23 | 1995-08-29 | Royer; Catherine A. | Quantitative detection of macromolecules with fluorescent oligonucleotides |
| GB9310978D0 (en) * | 1993-05-27 | 1993-07-14 | Zeneca Ltd | Compounds |
| DE4429239A1 (de) | 1994-08-18 | 1996-02-22 | Basf Ag | Verfahren zur Fluoreszenz-Korrelations-Spektroskopie und Vorrichtung zu dessen Durchführung |
| FI101829B1 (fi) * | 1995-03-07 | 1998-08-31 | Erkki Juhani Soini | Biospesifinen määritysmenetelmä |
| DE19630956A1 (de) * | 1996-07-31 | 1998-02-05 | Basf Ag | Verfahren und Vorrichtung zur Raman-Korrelationsspektroskopie |
| US5998204A (en) * | 1997-03-14 | 1999-12-07 | The Regents Of The University Of California | Fluorescent protein sensors for detection of analytes |
| US6208886B1 (en) * | 1997-04-04 | 2001-03-27 | The Research Foundation Of City College Of New York | Non-linear optical tomography of turbid media |
| EP0884583A1 (en) * | 1997-06-10 | 1998-12-16 | Evotec BioSystems GmbH | A method for characterizing samples in at least two dimensional space of specific physical properties |
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| DE69811724T2 (de) * | 1997-12-05 | 2003-10-16 | Pharmacia & Upjohn Co., Kalamazoo | Fluoreszenz-basierte hts-(high throughput screening)assayverfahren für proteinkinase und phosphatase |
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| WO1999034195A1 (de) * | 1997-12-23 | 1999-07-08 | Evotec Biosystems Ag | Verfahren zum nachweis von reaktionen mittels koinzidenzanalyse |
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| GB0116853D0 (en) | 2001-07-10 | 2001-09-05 | Torsana Diabetes Diagnostics A | Optical sensor containing particles for in SITU measurement of analytes |
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2003
- 2003-08-01 EP EP03767160A patent/EP1527333A1/en not_active Withdrawn
- 2003-08-01 CA CA002494478A patent/CA2494478A1/en not_active Abandoned
- 2003-08-01 AU AU2003259056A patent/AU2003259056B2/en not_active Expired - Fee Related
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- 2003-08-01 CA CA002493993A patent/CA2493993A1/en not_active Abandoned
- 2003-08-01 WO PCT/US2003/024780 patent/WO2004013610A2/en not_active Ceased
- 2003-08-01 WO PCT/US2003/024369 patent/WO2004013620A1/en not_active Ceased
- 2003-08-01 EP EP03767274A patent/EP1546675A4/en not_active Withdrawn
- 2003-08-01 US US10/633,385 patent/US7268878B2/en not_active Expired - Fee Related
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- 2003-08-01 US US10/632,725 patent/US20040082080A1/en not_active Abandoned
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2007
- 2007-08-06 US US11/834,168 patent/US20070291254A1/en not_active Abandoned
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|---|---|---|---|---|
| JPH11502608A (ja) * | 1993-01-18 | 1999-03-02 | エボテック・バイオシステムズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 生体高分子の適応度を評価するための方法および装置 |
| JPH11326208A (ja) * | 1998-05-21 | 1999-11-26 | Bunshi Bio Photonics Kenkyusho:Kk | 解析方法および解析装置 |
| WO2001059436A2 (en) * | 2000-02-10 | 2001-08-16 | Evotec Oai Ag | Fluorescence intensity and lifetime distribution analysis |
| WO2002048693A1 (fr) * | 2000-12-14 | 2002-06-20 | Olympus Optical Co., Ltd. | Analyseur fluorometrique et analyse fluorometrique |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009522541A (ja) * | 2005-12-29 | 2009-06-11 | ビーエーエスエフ ソシエタス・ヨーロピア | 媒体中で化学化合物の相同性及び非相同性ならびに濃度を決定する方法 |
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| CA2494478A1 (en) | 2004-02-12 |
| US7268878B2 (en) | 2007-09-11 |
| CA2493993A1 (en) | 2004-02-12 |
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| US20070291254A1 (en) | 2007-12-20 |
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