JP2005533646A - サイズ排除イオン交換粒子 - Google Patents
サイズ排除イオン交換粒子 Download PDFInfo
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- JP2005533646A JP2005533646A JP2004524830A JP2004524830A JP2005533646A JP 2005533646 A JP2005533646 A JP 2005533646A JP 2004524830 A JP2004524830 A JP 2004524830A JP 2004524830 A JP2004524830 A JP 2004524830A JP 2005533646 A JP2005533646 A JP 2005533646A
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- ion exchange
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- NWGKJDSIEKMTRX-AAZCQSIUSA-N Sorbitan monooleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-AAZCQSIUSA-N 0.000 description 1
- LOPVAWVHGAWUPS-UHFFFAOYSA-M [2-hydroxy-3-(2-methylprop-2-enoyloxy)propyl]-trimethylazanium;chloride Chemical compound [Cl-].CC(=C)C(=O)OCC(O)C[N+](C)(C)C LOPVAWVHGAWUPS-UHFFFAOYSA-M 0.000 description 1
- 150000003926 acrylamides Chemical class 0.000 description 1
- 125000003647 acryloyl group Chemical group O=C([*])C([H])=C([H])[H] 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 150000001350 alkyl halides Chemical class 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 229920001222 biopolymer Polymers 0.000 description 1
- 229910021538 borax Inorganic materials 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000013626 chemical specie Substances 0.000 description 1
- 150000001805 chlorine compounds Chemical class 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000007334 copolymerization reaction Methods 0.000 description 1
- 239000011258 core-shell material Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000000539 dimer Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000011143 downstream manufacturing Methods 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical group [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 description 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 229910001410 inorganic ion Inorganic materials 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000011147 inorganic material Substances 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 238000007834 ligase chain reaction Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 125000005641 methacryl group Chemical group 0.000 description 1
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 description 1
- WFKDPJRCBCBQNT-UHFFFAOYSA-N n,2-dimethylprop-2-enamide Chemical compound CNC(=O)C(C)=C WFKDPJRCBCBQNT-UHFFFAOYSA-N 0.000 description 1
- 229940088644 n,n-dimethylacrylamide Drugs 0.000 description 1
- RQAKESSLMFZVMC-UHFFFAOYSA-N n-ethenylacetamide Chemical compound CC(=O)NC=C RQAKESSLMFZVMC-UHFFFAOYSA-N 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- WLGDAKIJYPIYLR-UHFFFAOYSA-M octane-1-sulfonate Chemical compound CCCCCCCCS([O-])(=O)=O WLGDAKIJYPIYLR-UHFFFAOYSA-M 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000005298 paramagnetic effect Effects 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- USHAGKDGDHPEEY-UHFFFAOYSA-L potassium persulfate Chemical compound [K+].[K+].[O-]S(=O)(=O)OOS([O-])(=O)=O USHAGKDGDHPEEY-UHFFFAOYSA-L 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000012264 purified product Substances 0.000 description 1
- 238000005956 quaternization reaction Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 238000007151 ring opening polymerisation reaction Methods 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 125000005372 silanol group Chemical group 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- KKCBUQHMOMHUOY-UHFFFAOYSA-N sodium oxide Chemical compound [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 description 1
- 229910001948 sodium oxide Inorganic materials 0.000 description 1
- CHQMHPLRPQMAMX-UHFFFAOYSA-L sodium persulfate Substances [Na+].[Na+].[O-]S(=O)(=O)OOS([O-])(=O)=O CHQMHPLRPQMAMX-UHFFFAOYSA-L 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229920006027 ternary co-polymer Polymers 0.000 description 1
- 238000005979 thermal decomposition reaction Methods 0.000 description 1
- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/14—Polymerisation; cross-linking
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J47/00—Ion-exchange processes in general; Apparatus therefor
- B01J47/018—Granulation; Incorporation of ion-exchangers in a matrix; Mixing with inert materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4005—Concentrating samples by transferring a selected component through a membrane
- G01N2001/4016—Concentrating samples by transferring a selected component through a membrane being a selective membrane, e.g. dialysis or osmosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39885202P | 2002-07-26 | 2002-07-26 | |
| US10/414,179 US20040018559A1 (en) | 2002-07-26 | 2003-04-14 | Size-exclusion ion-exchange particles |
| US10/413,935 US6833238B2 (en) | 2002-01-04 | 2003-04-14 | Petal-array support for use with microplates |
| US10/413,797 US20040016702A1 (en) | 2002-07-26 | 2003-04-14 | Device and method for purification of nucleic acids |
| PCT/US2003/023337 WO2004011141A1 (en) | 2002-07-26 | 2003-07-25 | Size-exclusion ion-exchange particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005533646A true JP2005533646A (ja) | 2005-11-10 |
| JP2005533646A5 JP2005533646A5 (https=) | 2006-08-10 |
Family
ID=31192375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004524830A Pending JP2005533646A (ja) | 2002-07-26 | 2003-07-25 | サイズ排除イオン交換粒子 |
Country Status (4)
| Country | Link |
|---|---|
| EP (3) | EP1525053A1 (https=) |
| JP (1) | JP2005533646A (https=) |
| AU (3) | AU2003254174A1 (https=) |
| WO (3) | WO2004011141A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010522069A (ja) * | 2007-03-19 | 2010-07-01 | センター フォー アプライド プロテオミックス アンド モレキュラー メディシン | バイオマーカーの収集のためのスマートヒドロゲル粒子 |
| JP2012500651A (ja) * | 2008-08-25 | 2012-01-12 | ジーイー・ヘルスケア・バイオサイエンス・コーポレイション | ゲノムｄｎａの精製のための簡単な負荷および溶離プロセス |
| WO2012162022A3 (en) * | 2011-05-20 | 2013-03-28 | Dober Chemical Corporation | Systems and methods for releasing additive components |
| JP2015527052A (ja) * | 2012-05-31 | 2015-09-17 | エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ | 負に帯電した粒子を用いたクロマトグラフィによるポリヌクレオチドの精製 |
| JP2021113242A (ja) * | 2020-01-16 | 2021-08-05 | 株式会社豊田中央研究所 | 冷却液 |
| JP2022109607A (ja) * | 2021-01-15 | 2022-07-28 | 株式会社豊田中央研究所 | 冷却液 |
| WO2026018885A1 (ja) * | 2024-07-17 | 2026-01-22 | 株式会社ダイセル | 経血管内投与用医薬組成物 |
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| US6627159B1 (en) | 2000-06-28 | 2003-09-30 | 3M Innovative Properties Company | Centrifugal filling of sample processing devices |
| US7347976B2 (en) | 2001-12-20 | 2008-03-25 | 3M Innovative Properties Company | Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix |
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| US7939249B2 (en) | 2003-12-24 | 2011-05-10 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and concentration step |
| JP2007522807A (ja) * | 2004-02-18 | 2007-08-16 | アプレラ コーポレイション | 高分子電解質コーティングされたサイズ排除イオン交換粒子 |
| SE0400490D0 (sv) * | 2004-02-26 | 2004-02-26 | Amersham Biosciences Ab | Plasmid purification |
| JP2008536478A (ja) * | 2005-02-15 | 2008-09-11 | アプレラ コーポレイション | 高分子電解質被覆イオン交換粒子 |
| WO2006089029A2 (en) | 2005-02-15 | 2006-08-24 | Applera Corporation | Polyelectrolyte-coated ion-exchange particles |
| US7378260B2 (en) * | 2005-04-01 | 2008-05-27 | Applera Corporation | Products and methods for reducing dye artifacts |
| US7754474B2 (en) | 2005-07-05 | 2010-07-13 | 3M Innovative Properties Company | Sample processing device compression systems and methods |
| US7323660B2 (en) | 2005-07-05 | 2008-01-29 | 3M Innovative Properties Company | Modular sample processing apparatus kits and modules |
| US7763210B2 (en) | 2005-07-05 | 2010-07-27 | 3M Innovative Properties Company | Compliant microfluidic sample processing disks |
| DE102007005655A1 (de) | 2007-01-31 | 2008-08-07 | Qiagen Gmbh | Vorrichtung und Verfahren zur Aufreinigung von Nukleinsäuren |
| US8834792B2 (en) | 2009-11-13 | 2014-09-16 | 3M Innovative Properties Company | Systems for processing sample processing devices |
| JP2013530406A (ja) | 2010-07-09 | 2013-07-25 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | クロマトグラフィー方法及びそれに使用される媒体 |
| EP2638156B1 (de) | 2010-11-09 | 2016-01-27 | Qiagen GmbH | Verfahren und vorrichtung zur isolierung und reinigung von doppelsträngigen nukleinsäuren |
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2003
- 2003-07-25 EP EP03771854A patent/EP1525053A1/en not_active Withdrawn
- 2003-07-25 AU AU2003254174A patent/AU2003254174A1/en not_active Abandoned
- 2003-07-25 EP EP03771827A patent/EP1525299A2/en not_active Withdrawn
- 2003-07-25 WO PCT/US2003/023337 patent/WO2004011141A1/en not_active Ceased
- 2003-07-25 WO PCT/US2003/023338 patent/WO2004011142A1/en not_active Ceased
- 2003-07-25 AU AU2003254175A patent/AU2003254175A1/en not_active Abandoned
- 2003-07-25 JP JP2004524830A patent/JP2005533646A/ja active Pending
- 2003-07-25 WO PCT/US2003/023253 patent/WO2004011592A2/en not_active Ceased
- 2003-07-25 EP EP03771853A patent/EP1525052A1/en not_active Withdrawn
- 2003-07-25 AU AU2003256787A patent/AU2003256787A1/en not_active Abandoned
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Cited By (10)
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|---|---|---|---|---|
| JP2010522069A (ja) * | 2007-03-19 | 2010-07-01 | センター フォー アプライド プロテオミックス アンド モレキュラー メディシン | バイオマーカーの収集のためのスマートヒドロゲル粒子 |
| JP2012500651A (ja) * | 2008-08-25 | 2012-01-12 | ジーイー・ヘルスケア・バイオサイエンス・コーポレイション | ゲノムｄｎａの精製のための簡単な負荷および溶離プロセス |
| WO2012162022A3 (en) * | 2011-05-20 | 2013-03-28 | Dober Chemical Corporation | Systems and methods for releasing additive components |
| JP2015527052A (ja) * | 2012-05-31 | 2015-09-17 | エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ | 負に帯電した粒子を用いたクロマトグラフィによるポリヌクレオチドの精製 |
| US9890376B2 (en) | 2012-05-31 | 2018-02-13 | Agency For Science, Technology And Research | Chromatographic purification of polynucleotides with negatively charged particles |
| JP2021113242A (ja) * | 2020-01-16 | 2021-08-05 | 株式会社豊田中央研究所 | 冷却液 |
| JP7194129B2 (ja) | 2020-01-16 | 2022-12-21 | 株式会社豊田中央研究所 | 冷却液 |
| JP2022109607A (ja) * | 2021-01-15 | 2022-07-28 | 株式会社豊田中央研究所 | 冷却液 |
| JP7480070B2 (ja) | 2021-01-15 | 2024-05-09 | 株式会社豊田中央研究所 | 冷却液 |
| WO2026018885A1 (ja) * | 2024-07-17 | 2026-01-22 | 株式会社ダイセル | 経血管内投与用医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004011592A3 (en) | 2004-04-22 |
| AU2003256787A1 (en) | 2004-02-16 |
| EP1525052A1 (en) | 2005-04-27 |
| AU2003254175A1 (en) | 2004-02-16 |
| AU2003254174A1 (en) | 2004-02-16 |
| WO2004011142A1 (en) | 2004-02-05 |
| WO2004011141A1 (en) | 2004-02-05 |
| WO2004011592A2 (en) | 2004-02-05 |
| AU2003256787A8 (en) | 2004-02-16 |
| EP1525299A2 (en) | 2005-04-27 |
| EP1525053A1 (en) | 2005-04-27 |
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