JP2005532256A5 - - Google Patents
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- Publication number
- JP2005532256A5 JP2005532256A5 JP2003543537A JP2003543537A JP2005532256A5 JP 2005532256 A5 JP2005532256 A5 JP 2005532256A5 JP 2003543537 A JP2003543537 A JP 2003543537A JP 2003543537 A JP2003543537 A JP 2003543537A JP 2005532256 A5 JP2005532256 A5 JP 2005532256A5
- Authority
- JP
- Japan
- Prior art keywords
- lir
- pharmaceutical composition
- drug
- agent
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003795 chemical substances by application Substances 0.000 claims 11
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 239000003814 drug Substances 0.000 claims 9
- 101000984197 Homo sapiens Leukocyte immunoglobulin-like receptor subfamily A member 2 Proteins 0.000 claims 7
- 101000984189 Homo sapiens Leukocyte immunoglobulin-like receptor subfamily B member 2 Proteins 0.000 claims 7
- 102100025586 Leukocyte immunoglobulin-like receptor subfamily A member 2 Human genes 0.000 claims 7
- 102100025583 Leukocyte immunoglobulin-like receptor subfamily B member 2 Human genes 0.000 claims 7
- 229940079593 drug Drugs 0.000 claims 7
- 102100025582 Leukocyte immunoglobulin-like receptor subfamily B member 3 Human genes 0.000 claims 5
- 101710145805 Leukocyte immunoglobulin-like receptor subfamily B member 3 Proteins 0.000 claims 5
- 230000001270 agonistic effect Effects 0.000 claims 4
- 239000005557 antagonist Substances 0.000 claims 3
- 101100128404 Caenorhabditis elegans lir-3 gene Proteins 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 108010002352 Interleukin-1 Proteins 0.000 claims 1
- 229940035676 analgesics Drugs 0.000 claims 1
- 230000003042 antagnostic effect Effects 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 239000003435 antirheumatic agent Substances 0.000 claims 1
- 239000002988 disease modifying antirheumatic drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33589901P | 2001-11-14 | 2001-11-14 | |
| PCT/US2002/036372 WO2003041650A2 (en) | 2001-11-14 | 2002-11-12 | Modulation of lir function to treat rheumatoid arthritis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005532256A JP2005532256A (ja) | 2005-10-27 |
| JP2005532256A5 true JP2005532256A5 (enExample) | 2006-01-12 |
Family
ID=30770813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003543537A Pending JP2005532256A (ja) | 2001-11-14 | 2002-11-12 | 慢性関節リウマチを治療するためのｌｉｒ機能の調節 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050238643A1 (enExample) |
| EP (1) | EP1453540A4 (enExample) |
| JP (1) | JP2005532256A (enExample) |
| AU (1) | AU2002360376B2 (enExample) |
| CA (1) | CA2466118A1 (enExample) |
| MX (1) | MXPA04004491A (enExample) |
| PL (1) | PL374463A1 (enExample) |
| WO (1) | WO2003041650A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006049215A1 (ja) * | 2004-11-02 | 2006-05-11 | Dainippon Sumitomo Pharma Co., Ltd. | 自己免疫疾患を治療するための併用薬 |
| GB0510627D0 (en) | 2005-05-25 | 2005-06-29 | Avidex Ltd | Polypeptides |
| CA2611519A1 (en) | 2005-06-17 | 2006-12-28 | Tolerx, Inc. | Ilt3 binding molecules and uses therefor |
| WO2008094176A2 (en) | 2006-06-19 | 2008-08-07 | Tolerx, Inc. | Ilt3 binding molecules and uses therefor |
| CN102089327A (zh) * | 2008-05-13 | 2011-06-08 | 健泰科生物技术公司 | 抗PirB抗体 |
| WO2010101192A1 (ja) * | 2009-03-03 | 2010-09-10 | 国立大学法人九州大学 | 関節リウマチまたはその関連疾患の予防または治療剤 |
| EP2525822B1 (en) * | 2010-01-20 | 2017-05-10 | Merck Sharp & Dohme Corp. | Immunoregulation by anti-ilt5 antibodies and ilt5-binding antibody fragments |
| CA2787783A1 (en) * | 2010-01-20 | 2011-07-28 | Tolerx, Inc. | Anti-ilt5 antibodies and ilt5-binding antibody fragments |
| WO2014078956A1 (en) * | 2012-11-20 | 2014-05-30 | Revive Therapeutics Inc. | The use of bucillamine in the treatment of gout |
| TWI796329B (zh) | 2017-04-07 | 2023-03-21 | 美商默沙東有限責任公司 | 抗－ilt4抗體及抗原結合片段 |
| JP7391868B2 (ja) | 2017-12-22 | 2023-12-05 | ジョウンセ セラピューティクス， インク． | Ｌｉｌｒｂ２に対する抗体 |
| AU2019302454A1 (en) | 2018-07-09 | 2021-02-25 | Bristol-Myers Squibb Company | Antibodies binding to ILT4 |
| WO2021160838A1 (en) * | 2020-02-12 | 2021-08-19 | Bioinvent International Ab | Lilrb3 antibody molecules and uses thereof |
| IL297748A (en) | 2020-05-01 | 2022-12-01 | Ngm Biopharmaceuticals Inc | ilt binding agents and methods of using them |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2278154A1 (en) * | 1997-01-21 | 1998-07-23 | Human Genome Sciences, Inc. | Fc receptors and polypeptides |
| US6448035B1 (en) * | 1997-04-24 | 2002-09-10 | Immunex Corporation | Family of immunoregulators designated leukocyte immunoglobulin-like receptor (LIR) |
| US6384203B1 (en) * | 1999-05-12 | 2002-05-07 | Immunex Corporation | Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR) |
| CA2398251A1 (en) * | 2000-01-25 | 2001-08-02 | Hyseq, Inc. | Methods and materials relating to leukocyte immunoglobulin receptor-like (lir-like) polypeptides and polynucleotides |
-
2002
- 2002-11-12 WO PCT/US2002/036372 patent/WO2003041650A2/en not_active Ceased
- 2002-11-12 AU AU2002360376A patent/AU2002360376B2/en not_active Ceased
- 2002-11-12 JP JP2003543537A patent/JP2005532256A/ja active Pending
- 2002-11-12 EP EP02795627A patent/EP1453540A4/en not_active Ceased
- 2002-11-12 PL PL02374463A patent/PL374463A1/xx unknown
- 2002-11-12 MX MXPA04004491A patent/MXPA04004491A/es unknown
- 2002-11-12 US US10/495,695 patent/US20050238643A1/en not_active Abandoned
- 2002-11-12 CA CA002466118A patent/CA2466118A1/en not_active Abandoned
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