JP2005518339A - 対応する（Ｚ）エナミドの鏡像選択的水素化によりエナンチオリッチなＮ−アシル−β−アミノ酸誘導体の製造方法 - Google Patents

対応する（Ｚ）エナミドの鏡像選択的水素化によりエナンチオリッチなＮ−アシル−β−アミノ酸誘導体の製造方法 Download PDF

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JP2005518339A
JP2005518339A JP2003521193A JP2003521193A JP2005518339A JP 2005518339 A JP2005518339 A JP 2005518339A JP 2003521193 A JP2003521193 A JP 2003521193A JP 2003521193 A JP2003521193 A JP 2003521193A JP 2005518339 A JP2005518339 A JP 2005518339A
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alkyl
enamide
group
formula
carbon atoms
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Japanese (ja)
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ギヨーム マラン，クリストフ
コブリー，クリストファー
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ダウ グローバル テクノロジーズ インコーポレイティド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2003521193A 2001-08-17 2002-08-16 対応する（Ｚ）エナミドの鏡像選択的水素化によりエナンチオリッチなＮ−アシル−β−アミノ酸誘導体の製造方法 Pending JP2005518339A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0120167A GB0120167D0 (en) 2001-08-17 2001-08-17 Asymmetric hydrogenation
PCT/US2002/026142 WO2003016264A1 (fr) 2001-08-17 2002-08-16 Procede de preparation de derives de n-acyl-beta-amino acides enrichis en enantiomeres par hydrogenation enantioselective de (z)-enamides correspondants

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JP2005518339A true JP2005518339A (ja) 2005-06-23

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JP2003521193A Pending JP2005518339A (ja) 2001-08-17 2002-08-16 対応する（Ｚ）エナミドの鏡像選択的水素化によりエナンチオリッチなＮ−アシル−β−アミノ酸誘導体の製造方法

Country Status (4)

Country Link
EP (1) EP1421059A1 (fr)
JP (1) JP2005518339A (fr)
GB (1) GB0120167D0 (fr)
WO (1) WO2003016264A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006521354A (ja) * 2003-03-19 2006-09-21 メルク　エンド　カムパニー　インコーポレーテッド 不斉水素化によるキラルなベータアミノ酸誘導体の製造方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1579627A (zh) * 2003-08-05 2005-02-16 中国科学院大连化学物理研究所 一种手性配体金属络合物催化体系及制法和应用
DE102005014054A1 (de) * 2005-03-23 2006-09-28 Degussa Ag Elektronenarme Bisphospholanliganden und -katalysatoren
WO2011146610A2 (fr) * 2010-05-19 2011-11-24 Dr. Reddy's Laboratories Ltd. Synthèse énantiosélective d'amines chirales pour la production de rotigotine
MX2012014574A (es) 2010-06-15 2013-02-07 Bayer Ip Gmbh Derivados diamidoantranilicos que tienen cadenas laterales ciclicas.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG42936A1 (en) * 1992-04-02 1997-10-17 Ciba Geigy Ag Ferrocenyl diphosphines as ligands for homogeneous catalysts
JP3493206B2 (ja) * 1993-03-19 2004-02-03 ダイセル化学工業株式会社 光学活性β−アミノ酸類の製法
DE10100971A1 (de) * 2001-01-11 2002-07-18 Degussa Verfahren zur Herstellung enantiomerenangereicherter beta-Aminosäure

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006521354A (ja) * 2003-03-19 2006-09-21 メルク　エンド　カムパニー　インコーポレーテッド 不斉水素化によるキラルなベータアミノ酸誘導体の製造方法

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WO2003016264A1 (fr) 2003-02-27
EP1421059A1 (fr) 2004-05-26
GB0120167D0 (en) 2001-10-10

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