JP2005514957A - 遺伝子発現を調節するための核膜および核ラミナ結合キメラ - Google Patents

遺伝子発現を調節するための核膜および核ラミナ結合キメラ Download PDF

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JP2005514957A
JP2005514957A JP2003562314A JP2003562314A JP2005514957A JP 2005514957 A JP2005514957 A JP 2005514957A JP 2003562314 A JP2003562314 A JP 2003562314A JP 2003562314 A JP2003562314 A JP 2003562314A JP 2005514957 A JP2005514957 A JP 2005514957A
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protein
domain
binding
threonine
chimeric protein
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JP2003562314A
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JP2005514957A5 (enExample
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貴史 世良
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Syngenta Participations AG
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Syngenta Participations AG
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Publication of JP2005514957A publication Critical patent/JP2005514957A/ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8217Gene switch
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/80Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C07K2319/81Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
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  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2003562314A 2002-01-18 2003-01-17 遺伝子発現を調節するための核膜および核ラミナ結合キメラ Pending JP2005514957A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35016302P 2002-01-18 2002-01-18
US35131502P 2002-01-23 2002-01-23
PCT/US2003/001529 WO2003062447A2 (en) 2002-01-18 2003-01-17 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression

Publications (2)

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JP2005514957A true JP2005514957A (ja) 2005-05-26
JP2005514957A5 JP2005514957A5 (enExample) 2006-01-05

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ID=27616763

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JP2003562314A Pending JP2005514957A (ja) 2002-01-18 2003-01-17 遺伝子発現を調節するための核膜および核ラミナ結合キメラ

Country Status (7)

Country Link
US (1) US20050170348A1 (enExample)
EP (1) EP1485108A4 (enExample)
JP (1) JP2005514957A (enExample)
CN (1) CN100584945C (enExample)
AU (1) AU2003212816B2 (enExample)
CA (1) CA2472729A1 (enExample)
WO (1) WO2003062447A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2555659T3 (es) * 2005-11-07 2016-01-07 Cropdesign N.V. Plantas que tienen características de crecimiento mejoradas y un procedimiento de producción de las mismas
US9404123B2 (en) 2011-10-12 2016-08-02 National Centre For Biological Sciences Nucleic acid assembly, vector, cell, methods and kit thereof
CN109112142B (zh) * 2018-07-30 2021-02-12 华中农业大学 OsNMCP1基因在控制水稻耐旱中的应用
CN111793707B (zh) * 2020-06-23 2022-04-22 中国农业科学院油料作物研究所 一种基因编辑转基因作物编辑位点特异性pcr方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004567A1 (en) * 1992-08-21 1994-03-03 La Jolla Cancer Research Foundation A matrix-associating dna-protein, nucleic acids encoding the same and methods for detecting the nucleic acids
AU8157198A (en) * 1997-06-20 1999-01-04 Massachusetts Institute Of Technology Nuclear matrix targeting peptides and uses therefor
US6482646B1 (en) * 1998-11-06 2002-11-19 E. I. Du Pont De Nemours And Company Plant proteins that interact with nuclear matrix proteins and function as transcriptional activators

Also Published As

Publication number Publication date
AU2003212816B2 (en) 2008-02-07
EP1485108A4 (en) 2006-03-22
WO2003062447A3 (en) 2004-09-30
US20050170348A1 (en) 2005-08-04
EP1485108A2 (en) 2004-12-15
WO2003062447A2 (en) 2003-07-31
CN1617732A (zh) 2005-05-18
CA2472729A1 (en) 2003-07-31
CN100584945C (zh) 2010-01-27

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