CA2472729A1 - Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression - Google Patents

Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression Download PDF

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Publication number
CA2472729A1
CA2472729A1 CA002472729A CA2472729A CA2472729A1 CA 2472729 A1 CA2472729 A1 CA 2472729A1 CA 002472729 A CA002472729 A CA 002472729A CA 2472729 A CA2472729 A CA 2472729A CA 2472729 A1 CA2472729 A1 CA 2472729A1
Authority
CA
Canada
Prior art keywords
protein
domain
binding
threonine
nuclear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002472729A
Other languages
English (en)
French (fr)
Inventor
Takashi Sera
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Participations AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2472729A1 publication Critical patent/CA2472729A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8217—Gene switch
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002472729A 2002-01-18 2003-01-17 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression Abandoned CA2472729A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US35016302P 2002-01-18 2002-01-18
US60/350,163 2002-01-18
US35131502P 2002-01-23 2002-01-23
US60/351,315 2002-01-23
PCT/US2003/001529 WO2003062447A2 (en) 2002-01-18 2003-01-17 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression

Publications (1)

Publication Number Publication Date
CA2472729A1 true CA2472729A1 (en) 2003-07-31

Family

ID=27616763

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002472729A Abandoned CA2472729A1 (en) 2002-01-18 2003-01-17 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression

Country Status (7)

Country Link
US (1) US20050170348A1 (enExample)
EP (1) EP1485108A4 (enExample)
JP (1) JP2005514957A (enExample)
CN (1) CN100584945C (enExample)
AU (1) AU2003212816B2 (enExample)
CA (1) CA2472729A1 (enExample)
WO (1) WO2003062447A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2555659T3 (es) * 2005-11-07 2016-01-07 Cropdesign N.V. Plantas que tienen características de crecimiento mejoradas y un procedimiento de producción de las mismas
US9404123B2 (en) 2011-10-12 2016-08-02 National Centre For Biological Sciences Nucleic acid assembly, vector, cell, methods and kit thereof
CN109112142B (zh) * 2018-07-30 2021-02-12 华中农业大学 OsNMCP1基因在控制水稻耐旱中的应用
CN111793707B (zh) * 2020-06-23 2022-04-22 中国农业科学院油料作物研究所 一种基因编辑转基因作物编辑位点特异性pcr方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004567A1 (en) * 1992-08-21 1994-03-03 La Jolla Cancer Research Foundation A matrix-associating dna-protein, nucleic acids encoding the same and methods for detecting the nucleic acids
AU8157198A (en) * 1997-06-20 1999-01-04 Massachusetts Institute Of Technology Nuclear matrix targeting peptides and uses therefor
US6482646B1 (en) * 1998-11-06 2002-11-19 E. I. Du Pont De Nemours And Company Plant proteins that interact with nuclear matrix proteins and function as transcriptional activators

Also Published As

Publication number Publication date
AU2003212816B2 (en) 2008-02-07
EP1485108A4 (en) 2006-03-22
WO2003062447A3 (en) 2004-09-30
US20050170348A1 (en) 2005-08-04
EP1485108A2 (en) 2004-12-15
JP2005514957A (ja) 2005-05-26
WO2003062447A2 (en) 2003-07-31
CN1617732A (zh) 2005-05-18
CN100584945C (zh) 2010-01-27

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20140812