AU2003212816B2 - Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression - Google Patents

Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression Download PDF

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Publication number
AU2003212816B2
AU2003212816B2 AU2003212816A AU2003212816A AU2003212816B2 AU 2003212816 B2 AU2003212816 B2 AU 2003212816B2 AU 2003212816 A AU2003212816 A AU 2003212816A AU 2003212816 A AU2003212816 A AU 2003212816A AU 2003212816 B2 AU2003212816 B2 AU 2003212816B2
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AU
Australia
Prior art keywords
protein
binding
nuclear
proteins
threonine
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Ceased
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AU2003212816A
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English (en)
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AU2003212816A1 (en
Inventor
Takashi Sera
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Syngenta Participations AG
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Syngenta Participations AG
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Application filed by Syngenta Participations AG filed Critical Syngenta Participations AG
Publication of AU2003212816A1 publication Critical patent/AU2003212816A1/en
Application granted granted Critical
Publication of AU2003212816B2 publication Critical patent/AU2003212816B2/en
Priority to AU2008201953A priority Critical patent/AU2008201953B2/en
Priority to AU2008201951A priority patent/AU2008201951B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8217—Gene switch
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2003212816A 2002-01-18 2003-01-17 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression Ceased AU2003212816B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2008201953A AU2008201953B2 (en) 2002-01-18 2008-05-02 Molecular switch comprising fusion proteins
AU2008201951A AU2008201951B2 (en) 2002-01-18 2008-05-02 Composition comprising nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US35016302P 2002-01-18 2002-01-18
US60/350,163 2002-01-18
US35131502P 2002-01-23 2002-01-23
US60/351,315 2002-01-23
PCT/US2003/001529 WO2003062447A2 (en) 2002-01-18 2003-01-17 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression

Related Child Applications (2)

Application Number Title Priority Date Filing Date
AU2008201953A Division AU2008201953B2 (en) 2002-01-18 2008-05-02 Molecular switch comprising fusion proteins
AU2008201951A Division AU2008201951B2 (en) 2002-01-18 2008-05-02 Composition comprising nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression

Publications (2)

Publication Number Publication Date
AU2003212816A1 AU2003212816A1 (en) 2003-09-18
AU2003212816B2 true AU2003212816B2 (en) 2008-02-07

Family

ID=27616763

Family Applications (1)

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AU2003212816A Ceased AU2003212816B2 (en) 2002-01-18 2003-01-17 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression

Country Status (7)

Country Link
US (1) US20050170348A1 (enExample)
EP (1) EP1485108A4 (enExample)
JP (1) JP2005514957A (enExample)
CN (1) CN100584945C (enExample)
AU (1) AU2003212816B2 (enExample)
CA (1) CA2472729A1 (enExample)
WO (1) WO2003062447A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1948807B1 (en) * 2005-11-07 2015-09-30 CropDesign N.V. Plants having improved growth characteristics and a method for making the same
US9404123B2 (en) 2011-10-12 2016-08-02 National Centre For Biological Sciences Nucleic acid assembly, vector, cell, methods and kit thereof
CN109112142B (zh) * 2018-07-30 2021-02-12 华中农业大学 OsNMCP1基因在控制水稻耐旱中的应用
CN111793707B (zh) * 2020-06-23 2022-04-22 中国农业科学院油料作物研究所 一种基因编辑转基因作物编辑位点特异性pcr方法及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000028054A2 (en) * 1998-11-06 2000-05-18 E.I. Du Pont De Nemours And Company Plant proteins that interact with nuclear matrix proteins and function as transcriptional activators
US6153729A (en) * 1997-06-20 2000-11-28 St. Jude's Children's Research Hospital Isolated nuclear matrix targeting peptide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004567A1 (en) * 1992-08-21 1994-03-03 La Jolla Cancer Research Foundation A matrix-associating dna-protein, nucleic acids encoding the same and methods for detecting the nucleic acids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153729A (en) * 1997-06-20 2000-11-28 St. Jude's Children's Research Hospital Isolated nuclear matrix targeting peptide
WO2000028054A2 (en) * 1998-11-06 2000-05-18 E.I. Du Pont De Nemours And Company Plant proteins that interact with nuclear matrix proteins and function as transcriptional activators

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ferrucci PF et al (1997) P N A S 94 (20): 10901-10906 *

Also Published As

Publication number Publication date
EP1485108A2 (en) 2004-12-15
WO2003062447A3 (en) 2004-09-30
US20050170348A1 (en) 2005-08-04
CN100584945C (zh) 2010-01-27
CA2472729A1 (en) 2003-07-31
JP2005514957A (ja) 2005-05-26
WO2003062447A2 (en) 2003-07-31
EP1485108A4 (en) 2006-03-22
CN1617732A (zh) 2005-05-18

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired