JP2005514380A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005514380A5 JP2005514380A5 JP2003548831A JP2003548831A JP2005514380A5 JP 2005514380 A5 JP2005514380 A5 JP 2005514380A5 JP 2003548831 A JP2003548831 A JP 2003548831A JP 2003548831 A JP2003548831 A JP 2003548831A JP 2005514380 A5 JP2005514380 A5 JP 2005514380A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- hydroxy
- benzyl
- phenylpentyl
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 0 *C(C(C(C(C1=NC*=C(*)C1)[U+])[U])O)N(*)* Chemical compound *C(C(C(C(C1=NC*=C(*)C1)[U+])[U])O)N(*)* 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33656601P | 2001-12-04 | 2001-12-04 | |
| PCT/US2002/040038 WO2003047576A1 (en) | 2001-12-04 | 2002-12-03 | Peptide isosteres containing a heterocycle useful in the treatment of alzheimer's disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005514380A JP2005514380A (ja) | 2005-05-19 |
| JP2005514380A5 true JP2005514380A5 (https=) | 2006-02-02 |
Family
ID=23316667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003548831A Abandoned JP2005514380A (ja) | 2001-12-04 | 2002-12-03 | アルツハイマー病の治療に有用な複素環を含むペプチドアイソスター |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050159460A1 (https=) |
| EP (1) | EP1450795A1 (https=) |
| JP (1) | JP2005514380A (https=) |
| AU (1) | AU2002357232A1 (https=) |
| BR (1) | BR0214731A (https=) |
| CA (1) | CA2469130A1 (https=) |
| MX (1) | MXPA04005451A (https=) |
| WO (1) | WO2003047576A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7459476B2 (en) | 2002-06-27 | 2008-12-02 | Elan Pharmaceuticals, Inc. | Methods for treating Alzheimer's disease using hydroxyethylene compounds containing a heterocyclic amide bond isostere |
| US7521481B2 (en) | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| US8173600B2 (en) * | 2004-04-30 | 2012-05-08 | Chiesi Farmaceutici S.P.A. | Caspase-2 inhibitors and their biological applications |
| US7273882B2 (en) * | 2005-06-21 | 2007-09-25 | Bristol-Myers Squibb Company | Aminoacetamide acyl guanidines as β-secretase inhibitors |
| WO2007002214A2 (en) * | 2005-06-21 | 2007-01-04 | Bristol-Myers Squibb Company | Acyl guanidines as beta-secretase inhibitors |
| WO2009005783A1 (en) * | 2007-06-28 | 2009-01-08 | Blanchette Rockefeller Neurosciences Institute | Peptides, compositions and methods for reducing beta-amyloid-mediated apoptosis |
| EP2225200B1 (en) | 2007-12-24 | 2013-10-16 | DSM IP Assets B.V. | Convergent synthesis of renin inhibitors and intermediates useful therein |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5552426A (en) * | 1994-04-29 | 1996-09-03 | Eli Lilly And Company | Methods for treating a physiological disorder associated with β-amyloid peptide |
| TR199901128T2 (xx) * | 1996-11-22 | 1999-07-21 | Elan Pharmaceuticals, Inc. | N-(aril/heteroarilasetil) amino asit esterler, bunu ihtiva eden farmas�tik bile�imler ve bu t�r bile�ikler kullanarak �-amiloit peptit sal�n�m�n� ve/veya bunun sentezlenmesini inhibe etme y�ntemleri. |
| DE60124080T2 (de) * | 2000-03-23 | 2007-03-01 | Elan Pharmaceuticals, Inc., San Francisco | Verbindungen und verfahren zur behandlung der alzheimerschen krankheit |
| EP1299352B1 (en) * | 2000-06-30 | 2005-12-28 | Elan Pharmaceuticals, Inc. | Compounds to treat alzheimer's disease |
-
2002
- 2002-12-03 CA CA002469130A patent/CA2469130A1/en not_active Abandoned
- 2002-12-03 EP EP02804521A patent/EP1450795A1/en not_active Withdrawn
- 2002-12-03 JP JP2003548831A patent/JP2005514380A/ja not_active Abandoned
- 2002-12-03 WO PCT/US2002/040038 patent/WO2003047576A1/en not_active Ceased
- 2002-12-03 US US10/497,810 patent/US20050159460A1/en not_active Abandoned
- 2002-12-03 BR BR0214731-9A patent/BR0214731A/pt not_active IP Right Cessation
- 2002-12-03 AU AU2002357232A patent/AU2002357232A1/en not_active Abandoned
- 2002-12-03 MX MXPA04005451A patent/MXPA04005451A/es not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12021500049A1 (en) | 2,3-dihydroquinazolin compounds as nav1.8 inhibitors | |
| WO2004094384A3 (en) | (hetero) arylamide 2-hydroxy-3-diaminoalkanes for use in the treatment of alzheimer’s disease | |
| WO2004022523A3 (en) | 1, 3-diamino-2-hydroxypropane prodrug derivatives | |
| JP7778745B2 (ja) | Ｒｈｏ関連コイルドコイル含有プロテインキナーゼの阻害剤 | |
| EP3630101B1 (en) | Tegavivint for use in the treatment of pulmonary fibrosis | |
| AP2004002952A0 (en) | N-(3-amino-2-hydroxy-propyl) substituted alkylamide compounds. | |
| KR20010079616A (ko) | 과도한 물질 ｐ에 의해 야기된 문제점을 치료하기 위한약물 제조에 사용되는 아릴(또는헤테로아릴)아졸일카르비놀 유도체의 용도 | |
| WO2003027068A3 (en) | Substituted amines for the treatment of neurological disorders | |
| US10016397B2 (en) | Selective AT2 receptor agonists for use in treatment of cachexia | |
| WO2007056219A3 (en) | [4-(6-halo-7-substituted-2,4-dioxo-1,4-dihydro-2h-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylureas and forms and methods related thereto | |
| US20050107356A1 (en) | Combination of a CB1 receptor antagonist and of a product which activates dopaminergic neurotransmission in the brain, the pharmaceutical compositions comprising them and their use in the treatment of parkinson's disease | |
| JP2005508940A5 (https=) | ||
| KR20200139721A (ko) | 섬유성 질환을 치료하는 방법 | |
| WO2002100818A3 (en) | Aminediols as agents for the treatment of alzheimer's disease | |
| ES3057235T3 (en) | Isoxazolidines as ripk1 inhibitors and use thereof | |
| MX2008016083A (es) | Metodo para modular la excrecion de neuritas por el uso de un antagonista del receptor de galanina-3. | |
| JP2005514380A5 (https=) | ||
| JP2014527542A (ja) | 骨がんの治療に使用するためまたは原発がん細胞の骨への転移性播種を予防するためのｐｉ３ｋ阻害剤 | |
| JP4841433B2 (ja) | 治療的処置 | |
| JP2005514370A5 (https=) | ||
| CA2680324A1 (en) | Methods for treating cognitive disorders using 3-aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroaryl-3-hydroxy-2-amino-propionic acid amides and related compounds | |
| JP2008534541A5 (https=) | ||
| JP2018502911A5 (https=) | ||
| JP2011509982A (ja) | 上皮起源からのガン転移を防ぎ又は処置する為のアミノペプチダーゼインヒビター又はアザインドール化合物の使用 | |
| US10507228B2 (en) | Methods and compositions related to KRAS inhibitors |