JP2005512515A5 - - Google Patents
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- Publication number
- JP2005512515A5 JP2005512515A5 JP2003527073A JP2003527073A JP2005512515A5 JP 2005512515 A5 JP2005512515 A5 JP 2005512515A5 JP 2003527073 A JP2003527073 A JP 2003527073A JP 2003527073 A JP2003527073 A JP 2003527073A JP 2005512515 A5 JP2005512515 A5 JP 2005512515A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- nucleic acid
- cell
- acid molecule
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 51
- 102000004196 processed proteins & peptides Human genes 0.000 claims 51
- 108090000765 processed proteins & peptides Proteins 0.000 claims 51
- 238000000034 method Methods 0.000 claims 34
- 150000007523 nucleic acids Chemical class 0.000 claims 28
- 210000004027 cell Anatomy 0.000 claims 24
- 108020004707 nucleic acids Proteins 0.000 claims 24
- 102000039446 nucleic acids Human genes 0.000 claims 24
- 239000000523 sample Substances 0.000 claims 15
- 201000010099 disease Diseases 0.000 claims 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 14
- 241001465754 Metazoa Species 0.000 claims 10
- 125000003275 alpha amino acid group Chemical class 0.000 claims 9
- 239000000126 substance Substances 0.000 claims 9
- 230000000694 effects Effects 0.000 claims 8
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 239000013068 control sample Substances 0.000 claims 4
- 108700019146 Transgenes Proteins 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 241000238631 Hexapoda Species 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 230000002159 abnormal effect Effects 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 230000001575 pathological effect Effects 0.000 claims 2
- 230000003334 potential effect Effects 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 210000005253 yeast cell Anatomy 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 230000007170 pathology Effects 0.000 claims 1
- 229940124606 potential therapeutic agent Drugs 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (26)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31812001P | 2001-09-07 | 2001-09-07 | |
| US31813001P | 2001-09-07 | 2001-09-07 | |
| US31821901P | 2001-09-07 | 2001-09-07 | |
| US31843001P | 2001-09-10 | 2001-09-10 | |
| US31876501P | 2001-09-12 | 2001-09-12 | |
| US32278101P | 2001-09-17 | 2001-09-17 | |
| US32281601P | 2001-09-17 | 2001-09-17 | |
| US32351901P | 2001-09-19 | 2001-09-19 | |
| US32363601P | 2001-09-20 | 2001-09-20 | |
| US32363101P | 2001-09-20 | 2001-09-20 | |
| US32509101P | 2001-09-25 | 2001-09-25 | |
| US32496901P | 2001-09-25 | 2001-09-25 | |
| US32499001P | 2001-09-26 | 2001-09-26 | |
| US35730302P | 2002-02-15 | 2002-02-15 | |
| US36097302P | 2002-02-28 | 2002-02-28 | |
| US36613102P | 2002-03-20 | 2002-03-20 | |
| US36775302P | 2002-03-25 | 2002-03-25 | |
| US36947902P | 2002-04-02 | 2002-04-02 | |
| US37953202P | 2002-05-10 | 2002-05-10 | |
| US38167202P | 2002-05-17 | 2002-05-17 | |
| US38166402P | 2002-05-17 | 2002-05-17 | |
| US38365102P | 2002-05-28 | 2002-05-28 | |
| US38401202P | 2002-05-29 | 2002-05-29 | |
| US39015502P | 2002-06-19 | 2002-06-19 | |
| US10/236,392 US20040067490A1 (en) | 2001-09-07 | 2002-09-06 | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| PCT/US2002/028596 WO2003023008A2 (en) | 2001-09-07 | 2002-09-09 | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005512515A JP2005512515A (ja) | 2005-05-12 |
| JP2005512515A5 true JP2005512515A5 (enExample) | 2006-01-05 |
Family
ID=32046248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003527073A Pending JP2005512515A (ja) | 2001-09-07 | 2002-09-09 | 治療ポリペプチド、同一物をコード化する核酸、および使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20040067490A1 (enExample) |
| EP (1) | EP1576086A2 (enExample) |
| JP (1) | JP2005512515A (enExample) |
| CA (1) | CA2451454A1 (enExample) |
| WO (1) | WO2003023008A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001010902A2 (en) * | 1999-08-11 | 2001-02-15 | Curagen Corporation | Nucleoc acids and secreted polypeptides encoded thereby |
| FR2820739B1 (fr) | 2001-02-13 | 2004-01-02 | Ajinomoto Kk | Derive d'acide amine et gelifiant, composition de gel et cosmetique le contenant, et procedes de preparation correspondants |
| US20030077775A1 (en) * | 2001-10-17 | 2003-04-24 | Pe Corporation (Ny) | Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof |
| JP3955885B2 (ja) * | 2002-12-29 | 2007-08-08 | 日産化学工業株式会社 | アディポネクチン受容体及びそれをコードする遺伝子 |
| EP2902491A1 (en) | 2003-03-19 | 2015-08-05 | Biogen MA Inc. | NOGO receptor binding protein |
| WO2004094608A2 (en) * | 2003-04-18 | 2004-11-04 | Curagen Corporation | Human procolipase like nucleic acids and polypeptides and their methods of use threof |
| JP2007506951A (ja) | 2003-09-27 | 2007-03-22 | バイエル・ヘルスケア・エルエルシー | Gタンパク質共役受容体AdipoR1(AdipoR1)に関連する疾患の診断および治療 |
| DK1776136T3 (da) | 2004-06-24 | 2012-12-03 | Biogen Idec Inc | Behandling af tilstande, der involverer demyelinisering |
| BRPI0613387A2 (pt) | 2005-07-08 | 2011-01-11 | Biogen Idec Inc | anticorpo isolado ou fragmento de ligação de antìgeno deste e o seu uso, polinucleotìdeo isolado, composição, vetor, célula hospedeira, anticorpo anti-sp35 e método para a produção do mesmo, polipeptìdeo isolado, método in vitro para redução da inibição do crescimento axonal e método in vitro para inibição do crescimento do colapso do cone |
| US8093017B2 (en) | 2005-12-07 | 2012-01-10 | Siemens Heathcare Diagnostics Inc. | Detection of soluble adiponectin receptor peptides and use in diagnostics and therapeutics |
| US8128926B2 (en) | 2007-01-09 | 2012-03-06 | Biogen Idec Ma Inc. | Sp35 antibodies and uses thereof |
| WO2008091781A1 (en) * | 2007-01-22 | 2008-07-31 | Mayo Foundation For Medical Education And Research | Reducing tumor growth |
| CA2701189C (en) * | 2007-10-11 | 2017-05-16 | Biogen Idec Ma Inc. | Methods for treating pressure induced optic neuropathy, preventing neuronal degeneration and promoting neuronal cell survival via administration of lingo-1 antagonists and trkb agonists |
| AU2008325107B2 (en) * | 2007-11-08 | 2015-04-23 | Biogen Ma Inc. | Use of LINGO-4 antagonists in the treatment of conditions involving demyelination |
| CN101932728B (zh) | 2007-11-30 | 2013-06-19 | 西门子医疗保健诊断公司 | 脂连蛋白受体片段和使用方法 |
| ES2527072T3 (es) | 2008-03-19 | 2015-01-19 | China Synthetic Rubber Corporation | Procedimientos y agentes para el diagnóstico y el tratamiento de carcinoma hepatocelular |
| US8058406B2 (en) * | 2008-07-09 | 2011-11-15 | Biogen Idec Ma Inc. | Composition comprising antibodies to LINGO or fragments thereof |
| EP3199553B1 (en) | 2008-10-29 | 2019-04-24 | Circular Commitment Company | Methods and agents for the diagnosis and treatment of hepatocellular carcinoma |
| EP2422199B1 (en) | 2009-04-23 | 2018-07-25 | Siemens Healthcare Diagnostics Inc. | Monomeric and dimeric forms of adiponectin receptor fragments and methods of use |
| JP6401060B2 (ja) * | 2012-02-24 | 2018-10-03 | アッヴィ・ステムセントルクス・エル・エル・シー | 抗sez6抗体及び使用方法 |
| JP2015518829A (ja) | 2012-05-14 | 2015-07-06 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | 運動ニューロンに関する状態の処置のためのlingo−2アンタゴニスト |
| BR112016004242A8 (pt) * | 2013-08-28 | 2018-06-12 | Stemcentrx Inc | Métodos para conjugação sítio-específica de anticorpos e composições |
| US9993566B2 (en) | 2013-08-28 | 2018-06-12 | Abbvie Stemcentrx Llc | SEZ6 modulators and methods of use |
| US9493552B2 (en) | 2013-11-15 | 2016-11-15 | China Synthetic Rubber Corporation | Therapeutic biologic for treatment of hepatocellular carcinoma |
| KR20170008202A (ko) | 2014-02-21 | 2017-01-23 | 애브비 스템센트알엑스 엘엘씨 | 흑색종에 사용하기 위한 항-dll3 항체 및 약물 접합체 |
| HK1246810A1 (zh) | 2015-01-08 | 2018-09-14 | Biogen Ma Inc. | Lingo-1对抗药及用於治疗脱髓鞘疾病的用途 |
| CA3108731A1 (en) * | 2018-08-03 | 2020-02-06 | Scripps Health | Detection and isolation of myeloid-derived suppressor cell subpopulations |
| CN110208276B (zh) * | 2019-07-02 | 2023-03-31 | 广州越监工程质量安全检测中心有限公司 | 一种结构砼表观缺陷测定仪及其检测设备 |
| CN120272602B (zh) * | 2025-03-20 | 2025-12-23 | 江苏省家禽科学研究所 | Ston2基因中与开产日龄相关的遗传标记在蛋鸡遗传育种中的应用 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4873191A (en) * | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| US4485045A (en) * | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4522811A (en) * | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4870009A (en) * | 1982-11-22 | 1989-09-26 | The Salk Institute For Biological Studies | Method of obtaining gene product through the generation of transgenic animals |
| US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4544545A (en) * | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US4736866B1 (en) * | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4676980A (en) * | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US5225539A (en) * | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5116742A (en) * | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
| US4987071A (en) * | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| US4873316A (en) * | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| US5080891A (en) * | 1987-08-03 | 1992-01-14 | Ddi Pharmaceuticals, Inc. | Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols |
| US5639660A (en) * | 1988-02-24 | 1997-06-17 | Hoffmann-La Roche Inc. | Polypeptide and DNA sequence corresponding to the human receptor with high affinity for IgE |
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) * | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5272057A (en) * | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5328470A (en) * | 1989-03-31 | 1994-07-12 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
| US5459039A (en) * | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
| US5013556A (en) * | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5622930A (en) * | 1989-10-27 | 1997-04-22 | Clb | C1 inhibitor muteins and uses thereof |
| ATE356869T1 (de) * | 1990-01-12 | 2007-04-15 | Amgen Fremont Inc | Bildung von xenogenen antikörpern |
| US5661016A (en) * | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) * | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| CA2089661C (en) * | 1990-08-29 | 2007-04-03 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) * | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) * | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5527679A (en) * | 1991-05-01 | 1996-06-18 | Dana Farber Cancer Institute | β5 protein and DNA encoding the same |
| US6004924A (en) * | 1991-12-11 | 1999-12-21 | Imperial Cancer Research Technology, Ltd. | Protein sequences of serrate gene products |
| US5233409A (en) * | 1992-02-25 | 1993-08-03 | Schwab Karl W | Color analysis of organic constituents in sedimentary rocks for thermal maturity |
| WO1994007906A1 (en) * | 1992-10-01 | 1994-04-14 | Board Of Regents, The University Of Texas System | Epidermal surface antigen and uses thereof |
| EP0657811B1 (en) * | 1993-12-09 | 1998-09-02 | STMicroelectronics S.r.l. | Integrated circuitry for checking the utilization rate of redundancy memory elements in a semiconductor memory device |
| US5635360A (en) * | 1995-03-15 | 1997-06-03 | Becton, Dickinson And Company | Immunoassay for human restrictin |
| US5736866A (en) * | 1995-11-13 | 1998-04-07 | Kabushiki Kaisha Toshiba | Active pull-down circuit for ECL using a capacitive coupled circuit |
| US6083693A (en) * | 1996-06-14 | 2000-07-04 | Curagen Corporation | Identification and comparison of protein-protein interactions that occur in populations |
| US5916771A (en) * | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
| US6326472B1 (en) * | 1997-10-15 | 2001-12-04 | Schering Corporation | Human receptor proteins; related reagents and methods |
| WO2001010902A2 (en) * | 1999-08-11 | 2001-02-15 | Curagen Corporation | Nucleoc acids and secreted polypeptides encoded thereby |
| US20030211991A1 (en) * | 2001-04-17 | 2003-11-13 | Su Eric Wen | Human sez6 nucleic acids and polypeptides |
-
2002
- 2002-09-06 US US10/236,392 patent/US20040067490A1/en not_active Abandoned
- 2002-09-09 CA CA002451454A patent/CA2451454A1/en not_active Abandoned
- 2002-09-09 WO PCT/US2002/028596 patent/WO2003023008A2/en not_active Ceased
- 2002-09-09 EP EP02773310A patent/EP1576086A2/en not_active Withdrawn
- 2002-09-09 JP JP2003527073A patent/JP2005512515A/ja active Pending
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