JP2005510456A - ４−（フェニル−（ピペリジン−４−イル）−アミノ）−ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用 - Google Patents
４−（フェニル−（ピペリジン−４−イル）−アミノ）−ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用 Download PDFInfo
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- JP2005510456A JP2005510456A JP2002591456A JP2002591456A JP2005510456A JP 2005510456 A JP2005510456 A JP 2005510456A JP 2002591456 A JP2002591456 A JP 2002591456A JP 2002591456 A JP2002591456 A JP 2002591456A JP 2005510456 A JP2005510456 A JP 2005510456A
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- Prior art keywords
- phenyl
- fluoro
- piperidin
- amino
- benzamide
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
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- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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Landscapes
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101770A SE0101770D0 (sv) | 2001-05-18 | 2001-05-18 | Novel compounds |
| PCT/SE2002/000945 WO2002094783A1 (en) | 2001-05-18 | 2002-05-16 | 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005510456A true JP2005510456A (ja) | 2005-04-21 |
| JP2005510456A5 JP2005510456A5 (enExample) | 2005-12-22 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002591456A Pending JP2005510456A (ja) | 2001-05-18 | 2002-05-16 | ４−（フェニル−（ピペリジン−４−イル）−アミノ）−ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7064137B2 (enExample) |
| EP (1) | EP1395558B1 (enExample) |
| JP (1) | JP2005510456A (enExample) |
| KR (1) | KR20040000469A (enExample) |
| CN (1) | CN1620435A (enExample) |
| AR (1) | AR033759A1 (enExample) |
| AT (1) | ATE313529T1 (enExample) |
| BG (1) | BG108331A (enExample) |
| BR (1) | BR0209669A (enExample) |
| CA (1) | CA2446313A1 (enExample) |
| CO (1) | CO5540319A2 (enExample) |
| CZ (1) | CZ20033090A3 (enExample) |
| DE (1) | DE60208193T2 (enExample) |
| EE (1) | EE200300534A (enExample) |
| HU (1) | HUP0401608A2 (enExample) |
| IL (1) | IL158629A0 (enExample) |
| IS (1) | IS7031A (enExample) |
| MX (1) | MXPA03010441A (enExample) |
| NO (1) | NO20035112D0 (enExample) |
| PL (1) | PL366390A1 (enExample) |
| RU (1) | RU2003131967A (enExample) |
| SE (1) | SE0101770D0 (enExample) |
| SK (1) | SK13922003A3 (enExample) |
| WO (1) | WO2002094783A1 (enExample) |
| ZA (1) | ZA200308637B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0300987D0 (sv) * | 2003-04-03 | 2003-04-03 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| KR20140015122A (ko) | 2003-10-01 | 2014-02-06 | 아돌로 코포레이션 | 스피로시클릭 헤테로시클릭 유도체 및 이의 사용 방법 |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| WO2016099394A1 (en) * | 2014-12-19 | 2016-06-23 | Pharmnovo Ab | Novel selective delta-opioid receptor agonists useful for the treatment of pain, anxiety and depression. |
| US20250084091A1 (en) * | 2021-05-04 | 2025-03-13 | The Texas A&M University System | Inhibitors of sars-cov-2 |
| CN116554100B (zh) * | 2023-02-22 | 2025-08-15 | 江苏师范大学 | 一种钯催化合成菲啶酮类化合物的方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091096A (en) * | 1976-03-19 | 1978-05-23 | Eli Lilly And Company | Dinitroanilines for the control of phytopathogens |
| EG12406A (en) * | 1976-08-12 | 1979-03-31 | Janssen Pharmaceutica Nv | Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
| US4252812A (en) * | 1977-05-23 | 1981-02-24 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
| SE441448B (sv) | 1977-05-23 | 1985-10-07 | Pfizer | Sett att framstella hexahydro-gamma-karbolinforeningar |
| DE3200304A1 (de) * | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
| DE3563964D1 (en) * | 1984-10-16 | 1988-09-01 | Synthelabo | Piperidine derivatives, their preparation and their therapeutical application |
| YU150489A (sh) * | 1989-08-10 | 1992-12-21 | W.L. Gore & Co. Gmbh. | Uređaj za ispitivanje odevnih predmeta na nepromočivost |
| KR940003491B1 (ko) * | 1989-08-10 | 1994-04-23 | 리히터 게데온 베기에스제티 기아르 알.티 | 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물 |
| US5854245A (en) * | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| SE9604786D0 (sv) * | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| CA2316341A1 (en) | 1997-12-24 | 1999-07-08 | Ortho-Mcneil Pharmaceutical, Inc. | 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor |
| JP4498602B2 (ja) | 1998-03-10 | 2010-07-07 | リサーチ・トライアングル・インスティチュート | 新規なオピエート化合物、その調製法及び使用法 |
| SE9904675D0 (sv) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| US6552036B2 (en) * | 2000-03-03 | 2003-04-22 | Ortho-Mcneil Pharmaceutical, Inc. | 3-(Diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives |
| US6556387B1 (en) * | 2000-03-31 | 2003-04-29 | Seagate Technology Llc | Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly |
| SE0001207D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
2001
- 2001-05-18 SE SE0101770A patent/SE0101770D0/xx unknown
-
2002
- 2002-05-16 CA CA002446313A patent/CA2446313A1/en not_active Abandoned
- 2002-05-16 DE DE60208193T patent/DE60208193T2/de not_active Expired - Fee Related
- 2002-05-16 WO PCT/SE2002/000945 patent/WO2002094783A1/en not_active Ceased
- 2002-05-16 AR ARP020101815A patent/AR033759A1/es unknown
- 2002-05-16 EE EEP200300534A patent/EE200300534A/xx unknown
- 2002-05-16 JP JP2002591456A patent/JP2005510456A/ja active Pending
- 2002-05-16 HU HU0401608A patent/HUP0401608A2/hu unknown
- 2002-05-16 PL PL02366390A patent/PL366390A1/xx not_active Application Discontinuation
- 2002-05-16 BR BR0209669-2A patent/BR0209669A/pt not_active Application Discontinuation
- 2002-05-16 KR KR10-2003-7014948A patent/KR20040000469A/ko not_active Withdrawn
- 2002-05-16 EP EP02736338A patent/EP1395558B1/en not_active Expired - Lifetime
- 2002-05-16 IL IL15862902A patent/IL158629A0/xx unknown
- 2002-05-16 RU RU2003131967/04A patent/RU2003131967A/ru not_active Application Discontinuation
- 2002-05-16 SK SK1392-2003A patent/SK13922003A3/sk unknown
- 2002-05-16 CZ CZ20033090A patent/CZ20033090A3/cs unknown
- 2002-05-16 CN CNA028141709A patent/CN1620435A/zh active Pending
- 2002-05-16 MX MXPA03010441A patent/MXPA03010441A/es unknown
- 2002-05-16 US US10/477,853 patent/US7064137B2/en not_active Expired - Fee Related
- 2002-05-16 AT AT02736338T patent/ATE313529T1/de not_active IP Right Cessation
-
2003
- 2003-11-05 ZA ZA200308637A patent/ZA200308637B/en unknown
- 2003-11-07 BG BG108331A patent/BG108331A/bg unknown
- 2003-11-12 CO CO03100167A patent/CO5540319A2/es not_active Application Discontinuation
- 2003-11-13 IS IS7031A patent/IS7031A/is unknown
- 2003-11-17 NO NO20035112A patent/NO20035112D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SE0101770D0 (sv) | 2001-05-18 |
| EP1395558A1 (en) | 2004-03-10 |
| BR0209669A (pt) | 2004-04-20 |
| ATE313529T1 (de) | 2006-01-15 |
| RU2003131967A (ru) | 2005-05-10 |
| NO20035112D0 (no) | 2003-11-17 |
| US7064137B2 (en) | 2006-06-20 |
| EE200300534A (et) | 2004-02-16 |
| KR20040000469A (ko) | 2004-01-03 |
| EP1395558B1 (en) | 2005-12-21 |
| IL158629A0 (en) | 2004-05-12 |
| CA2446313A1 (en) | 2002-11-28 |
| DE60208193D1 (de) | 2006-01-26 |
| ZA200308637B (en) | 2005-02-07 |
| IS7031A (is) | 2003-11-13 |
| DE60208193T2 (de) | 2006-07-13 |
| MXPA03010441A (es) | 2004-03-09 |
| CN1620435A (zh) | 2005-05-25 |
| SK13922003A3 (sk) | 2004-04-06 |
| CO5540319A2 (es) | 2005-07-29 |
| US20040152731A1 (en) | 2004-08-05 |
| BG108331A (bg) | 2004-10-29 |
| WO2002094783A1 (en) | 2002-11-28 |
| PL366390A1 (en) | 2005-01-24 |
| HUP0401608A2 (hu) | 2004-12-28 |
| CZ20033090A3 (en) | 2004-06-16 |
| AR033759A1 (es) | 2004-01-07 |
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