JP2005509663A5 - - Google Patents

Info

Publication number

JP2005509663A5

JP2005509663A5 JP2003545313A JP2003545313A JP2005509663A5 JP 2005509663 A5 JP2005509663 A5 JP 2005509663A5 JP 2003545313 A JP2003545313 A JP 2003545313A JP 2003545313 A JP2003545313 A JP 2003545313A JP 2005509663 A5 JP2005509663 A5 JP 2005509663A5

Authority

JP

Japan

Prior art keywords

formula

day

days

administered

compound

Prior art date

2002-11-11

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 239000004480 active ingredient Substances 0.000 claims 23
• 150000001875 compounds Chemical class 0.000 claims 22
• SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 claims 22
• 229960005277 gemcitabine Drugs 0.000 claims 22
• 239000008194 pharmaceutical composition Substances 0.000 claims 18
• 206010028980 Neoplasm Diseases 0.000 claims 15
• 150000002148 esters Chemical class 0.000 claims 13
• 150000003839 salts Chemical class 0.000 claims 13
• 201000011510 cancer Diseases 0.000 claims 8
• 239000004615 ingredient Substances 0.000 claims 8
• 239000003814 drug Substances 0.000 claims 7
• 239000007787 solid Substances 0.000 claims 7
• 229940102223 injectable solution Drugs 0.000 claims 6
• LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 4
• 239000002552 dosage form Substances 0.000 claims 2
• 238000000034 method Methods 0.000 claims 2
• 239000002246 antineoplastic agent Substances 0.000 claims 1
• 238000009472 formulation Methods 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 239000000203 mixture Substances 0.000 claims 1
• 238000001959 radiotherapy Methods 0.000 claims 1
• 238000013268 sustained release Methods 0.000 claims 1
• 239000012730 sustained-release form Substances 0.000 claims 1