JP2005508630A5 - - Google Patents

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JP2005508630A5
JP2005508630A5 JP2003529906A JP2003529906A JP2005508630A5 JP 2005508630 A5 JP2005508630 A5 JP 2005508630A5 JP 2003529906 A JP2003529906 A JP 2003529906A JP 2003529906 A JP2003529906 A JP 2003529906A JP 2005508630 A5 JP2005508630 A5 JP 2005508630A5
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coli
deposited
peoria
nrrl
illinois
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JP2003529906A
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JP2005508630A (ja
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Priority claimed from PCT/US2002/029264 external-priority patent/WO2003025132A2/en
Publication of JP2005508630A publication Critical patent/JP2005508630A/ja
Publication of JP2005508630A5 publication Critical patent/JP2005508630A5/ja
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示したポリメラーゼをコードするプラスミドで形質転換した大腸菌 BL21 (DE3) の試料を、ブダペスト条約に従って、米国農業研究サービスカルチャーコレクション(Agricultural Research Service Culture Collection :NRRL)、1815 North University Street, Peoria, Illinois, 61604, USAに寄託した。エントリー11-15を、大腸菌 BL21 (SI) において寄託した。
Figure 2005508630
JP2003529906A 2001-09-14 2002-09-16 Dnaポリメラーゼとその変異体 Pending JP2005508630A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31890301P 2001-09-14 2001-09-14
PCT/US2002/029264 WO2003025132A2 (en) 2001-09-14 2002-09-16 Dna polymerases and mutants thereof

Publications (2)

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JP2005508630A JP2005508630A (ja) 2005-04-07
JP2005508630A5 true JP2005508630A5 (ja) 2006-01-05

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JP2003529906A Pending JP2005508630A (ja) 2001-09-14 2002-09-16 Dnaポリメラーゼとその変異体

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US (3) US20070020622A1 (ja)
EP (1) EP1436385A4 (ja)
JP (1) JP2005508630A (ja)
CA (1) CA2460546A1 (ja)
WO (1) WO2003025132A2 (ja)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
US7785608B2 (en) * 2002-08-30 2010-08-31 Wyeth Holdings Corporation Immunogenic compositions for the prevention and treatment of meningococcal disease
US7301554B2 (en) * 2002-09-20 2007-11-27 Ricoh Company, Ltd. Light scanning device, scanning line adjusting method, scanning line adjusting control method, image forming apparatus, and image forming method
JP2006525330A (ja) * 2003-04-16 2006-11-09 ワイエス・ホールディングス・コーポレーション 髄膜炎菌性疾患の予防および処置のための新規免疫原性組成物
US20070048748A1 (en) * 2004-09-24 2007-03-01 Li-Cor, Inc. Mutant polymerases for sequencing and genotyping
US9505846B2 (en) * 2005-01-28 2016-11-29 Life Technologies Corporation Multi-component inhibitors of nucleic acid polymerases
US20060292578A1 (en) 2005-06-28 2006-12-28 Weidong Zheng DNA polymerase blends and mutant DNA polymerases
WO2007143436A2 (en) * 2006-05-30 2007-12-13 Ge Healthcare Bio-Sciences Corp. Dna polymerase from spirochaeta thermophila
US8889348B2 (en) * 2006-06-07 2014-11-18 The Trustees Of Columbia University In The City Of New York DNA sequencing by nanopore using modified nucleotides
AR064642A1 (es) * 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
GB0806562D0 (en) 2008-04-10 2008-05-14 Fermentas Uab Production of nucleic acid
KR101151602B1 (ko) * 2009-12-15 2012-06-08 주식회사 인트론바이오테크놀로지 클레나우 단편을 이용한 rt-pcr 반응의 성능을 개선시키는 방법
US9678055B2 (en) 2010-02-08 2017-06-13 Genia Technologies, Inc. Methods for forming a nanopore in a lipid bilayer
US9605307B2 (en) 2010-02-08 2017-03-28 Genia Technologies, Inc. Systems and methods for forming a nanopore in a lipid bilayer
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
KR101409009B1 (ko) * 2010-03-31 2014-06-18 라쿠텐 인코포레이티드 정보 처리 장치, 정보 처리 방법, 및 기록 매체
HUE052850T2 (hu) 2010-08-23 2021-05-28 Wyeth Llc Neisseria meningitidis RLP2086 antigéneket tartalmazó stabil készítmények
NZ607224A (en) 2010-09-10 2014-11-28 Wyeth Llc Non-lipidated variants of neisseria meningitidis orf2086 antigens
US8932813B2 (en) 2010-12-13 2015-01-13 Life Technologies Corporation Polymerization of nucleic acids using activation by polyphosphorolysis (APP) reactions
US8845880B2 (en) 2010-12-22 2014-09-30 Genia Technologies, Inc. Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps
US8962242B2 (en) 2011-01-24 2015-02-24 Genia Technologies, Inc. System for detecting electrical properties of a molecular complex
US9110478B2 (en) 2011-01-27 2015-08-18 Genia Technologies, Inc. Temperature regulation of measurement arrays
ES2561885T3 (es) 2011-04-11 2016-03-01 F. Hoffmann-La Roche Ag ADN polimerasas de actividad mejorada
WO2013013822A1 (en) * 2011-07-28 2013-01-31 Roche Diagnostics Gmbh Dna polymerases with improved activity
EP2788479B1 (en) 2011-12-08 2016-02-10 Roche Diagnostics GmbH Dna polymerases with improved activity
JP6144697B2 (ja) 2011-12-08 2017-06-07 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 改善された活性を有するdnaポリメラーゼ
JP6224613B2 (ja) 2011-12-08 2017-11-01 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 改善された活性を有するdnaポリメラーゼ
US8986629B2 (en) 2012-02-27 2015-03-24 Genia Technologies, Inc. Sensor circuit for controlling, detecting, and measuring a molecular complex
KR101763625B1 (ko) 2012-03-09 2017-08-01 화이자 인코포레이티드 수막염균 조성물 및 이의 사용 방법
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
WO2013185137A1 (en) 2012-06-08 2013-12-12 Pacific Biosciences Of California, Inc. Modified base detection with nanopore sequencing
JP2015525077A (ja) 2012-06-15 2015-09-03 ジェニア・テクノロジーズ・インコーポレイテッド チップの構成および高精度な核酸配列決定
US8993298B1 (en) 2012-08-31 2015-03-31 New England Biolabs, Inc. DNA polymerases
WO2014062848A1 (en) 2012-10-16 2014-04-24 Dna Polymerase Technology, Inc. Inhibition-resistant polymerases
CN111793621A (zh) 2012-11-02 2020-10-20 生命技术公司 用于增强pcr特异性的新颖组合物、方法和试剂盒
US9605309B2 (en) 2012-11-09 2017-03-28 Genia Technologies, Inc. Nucleic acid sequencing using tags
US9759711B2 (en) 2013-02-05 2017-09-12 Genia Technologies, Inc. Nanopore arrays
ES2685894T3 (es) 2013-03-08 2018-10-15 Pfizer Inc. Polipéptidos de fusión inmunogénicos
CN105339505B (zh) 2013-03-12 2021-08-10 生命技术公司 基于通用报告体的基因分型方法和材料
RU2662968C2 (ru) 2013-09-08 2018-07-31 Пфайзер Инк. Иммуногенная композиция против neisseria meningitidis (варианты)
US9551697B2 (en) 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
US9322062B2 (en) 2013-10-23 2016-04-26 Genia Technologies, Inc. Process for biosensor well formation
EP3640349A3 (en) 2013-10-23 2020-07-29 Roche Sequencing Solutions, Inc. High speed molecular sensing with nanopores
JP6573899B2 (ja) 2013-11-17 2019-09-11 クアンタム−エスアイ インコーポレイテッドQuantum−Si Incorporated 分子をプローブし、検出し、及び分析するための、外部光源を備えた集積デバイス
EP3097190A2 (en) 2014-01-22 2016-11-30 Life Technologies Corporation Novel reverse transcriptases for use in high temperature nucleic acid synthesis
CN106796176B (zh) 2014-08-08 2021-02-05 宽腾矽公司 用于对分子进行探测、检测和分析的带外部光源的集成装置
KR102384909B1 (ko) 2014-08-08 2022-04-11 퀀텀-에스아이 인코포레이티드 수신된 광자들의 시간 비닝을 위한 집적 디바이스
JP6812341B2 (ja) 2014-08-08 2021-01-13 クアンタム−エスアイ インコーポレイテッドQuantum−Si Incorporated 分子の探索、検出及び解析のための光学システム及びアッセイチップ
EP3270959A1 (en) 2015-02-19 2018-01-24 Pfizer Inc Neisseria meningitidis compositions and methods thereof
WO2016149021A1 (en) 2015-03-13 2016-09-22 Life Technologies Corporation Methods, compositions and kits for small rna capture, detection and quantification
US11091745B2 (en) 2015-05-12 2021-08-17 Dna Polymerase Technology, Inc. Mutant polymerases and uses thereof
US10174363B2 (en) 2015-05-20 2019-01-08 Quantum-Si Incorporated Methods for nucleic acid sequencing
AU2017219894B2 (en) 2016-02-17 2021-12-09 Tesseract Health, Inc. Sensor and device for lifetime imaging and detection applications
BR112019012540A2 (pt) 2016-12-22 2019-11-12 Quantum-Si Incorporated fotodetector integrado com pixel de acondicionamento direto
US11236384B2 (en) 2017-01-19 2022-02-01 Asuragen, Inc. Methods of RNA amplification
SG11201906519RA (en) 2017-01-31 2019-08-27 Pfizer Neisseria meningitidis compositions and methods thereof
CN111094573A (zh) * 2017-07-12 2020-05-01 梅约医学教育与研究基金会 有效靶向敲入或基因置换的材料和方法
US10200071B1 (en) * 2017-08-07 2019-02-05 Kratos Integral Holdings, Llc System and method for interference reduction in radio communications
WO2019246328A1 (en) 2018-06-22 2019-12-26 Quantum-Si Incorporated Integrated photodetector with charge storage bin of varied detection time

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) * 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4588585A (en) * 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
US4737462A (en) * 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
US5116943A (en) * 1985-01-18 1992-05-26 Cetus Corporation Oxidation-resistant muteins of Il-2 and other protein
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) * 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US5017691A (en) * 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
US4879111A (en) * 1986-04-17 1989-11-07 Cetus Corporation Treatment of infections with lymphokines
US5618711A (en) * 1986-08-22 1997-04-08 Hoffmann-La Roche Inc. Recombinant expression vectors and purification methods for Thermus thermophilus DNA polymerase
US5374553A (en) * 1986-08-22 1994-12-20 Hoffmann-La Roche Inc. DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima
US5795762A (en) * 1986-08-22 1998-08-18 Roche Molecular Systems, Inc. 5' to 3' exonuclease mutations of thermostable DNA polymerases
US5322770A (en) * 1989-12-22 1994-06-21 Hoffman-Laroche Inc. Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
US5310652A (en) * 1986-08-22 1994-05-10 Hoffman-La Roche Inc. Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription
US5561058A (en) * 1986-08-22 1996-10-01 Hoffmann-La Roche Inc. Methods for coupled high temperatures reverse transcription and polymerase chain reactions
US5693517A (en) * 1987-06-17 1997-12-02 Roche Molecular Systems, Inc. Reagents and methods for coupled high temperature reverse transcription and polymerase chain reactions
US5407800A (en) * 1986-08-22 1995-04-18 Hoffmann-La Roche Inc. Reverse transcription with Thermus thermophilus polymerase
US5466591A (en) * 1986-08-22 1995-11-14 Hoffmann-La Roche Inc. 5' to 3' exonuclease mutations of thermostable DNA polymerases
US4889818A (en) * 1986-08-22 1989-12-26 Cetus Corporation Purified thermostable enzyme
US5173411A (en) * 1987-01-14 1992-12-22 President And Fellows Of Harvard College Method for determining the nucleotide base sequence of a DNA molecule
US4795699A (en) * 1987-01-14 1989-01-03 President And Fellows Of Harvard College T7 DNA polymerase
US4965195A (en) * 1987-10-26 1990-10-23 Immunex Corp. Interleukin-7
US4904584A (en) * 1987-12-23 1990-02-27 Genetics Institute, Inc. Site-specific homogeneous modification of polypeptides
US5244797B1 (en) * 1988-01-13 1998-08-25 Life Technologies Inc Cloned genes encoding reverse transcriptase lacking rnase h activity
US5498523A (en) * 1988-07-12 1996-03-12 President And Fellows Of Harvard College DNA sequencing with pyrophosphatase
US4962020A (en) * 1988-07-12 1990-10-09 President And Fellows Of Harvard College DNA sequencing
US5047342A (en) * 1989-08-10 1991-09-10 Life Technologies, Inc. Cloning and expression of T5 DNA polymerase
US5270179A (en) * 1989-08-10 1993-12-14 Life Technologies, Inc. Cloning and expression of T5 DNA polymerase reduced in 3'- to-5' exonuclease activity
US5994056A (en) * 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
EP1233061A3 (en) * 1991-06-03 2002-09-04 Takara Shuzo Co., Ltd. A method for cloning of a gene for pol I type DNA polymerase
US6759226B1 (en) * 2000-05-24 2004-07-06 Third Wave Technologies, Inc. Enzymes for the detection of specific nucleic acid sequences
US5338671A (en) * 1992-10-07 1994-08-16 Eastman Kodak Company DNA amplification with thermostable DNA polymerase and polymerase inhibiting antibody
US5541311A (en) * 1992-12-07 1996-07-30 Third Wave Technologies, Inc. Nucleic acid encoding synthesis-deficient thermostable DNA polymerase
US5405779A (en) * 1993-04-09 1995-04-11 Agracetus, Inc. Apparatus for genetic transformation
US5834252A (en) * 1995-04-18 1998-11-10 Glaxo Group Limited End-complementary polymerase reaction
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5837458A (en) * 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6100078A (en) * 1994-04-01 2000-08-08 Gen-Probe Incorporated Purified DNA polymerase from bacillus stearothermophilus ATCC 12980
US5912155A (en) * 1994-09-30 1999-06-15 Life Technologies, Inc. Cloned DNA polymerases from Thermotoga neapolitana
US6015668A (en) * 1994-09-30 2000-01-18 Life Technologies, Inc. Cloned DNA polymerases from thermotoga and mutants thereof
US5614365A (en) * 1994-10-17 1997-03-25 President & Fellow Of Harvard College DNA polymerase having modified nucleotide binding site for DNA sequencing
US5565340A (en) * 1995-01-27 1996-10-15 Clontech Laboratories, Inc. Method for suppressing DNA fragment amplification during PCR
US6270962B1 (en) * 1995-01-30 2001-08-07 The Regents Of The University Of California Methods for the elimination of DNA sequencing artifacts
CA2222744C (en) * 1995-05-31 2008-03-25 Amersham Life Science, Inc. Thermostable dna polymerases
US6077664A (en) * 1995-06-07 2000-06-20 Promega Corporation Thermophilic DNA polymerases from Thermotoga neapolitana
US20030027296A1 (en) * 1995-09-08 2003-02-06 Deb K. Chatterjee Cloned dna polymerases from thermotoga maritima and mutants thereof
US5948614A (en) * 1995-09-08 1999-09-07 Life Technologies, Inc. Cloned DNA polymerases from thermotoga maritima and mutants thereof
US6165765A (en) * 1995-10-18 2000-12-26 Shanghai Institute Of Biochemistry, Chinese Academy Of Sciences DNA polymerase having ability to reduce innate selective discrimination against fluorescent dye-labeled dideoxynucleotides
ES2162132T3 (es) * 1995-12-15 2001-12-16 Amersham Pharm Biotech Inc Polimerasa de adn termoestable procedente de thermoanaerobacter thermohydrosulfuricus y enzimas mutantes, de actividad exonucleasa suprimida asi obtenidos.
CZ293215B6 (cs) * 1996-08-06 2004-03-17 F. Hoffmann-La Roche Ag Rekombinantní tepelně stálá DNA polymeráza, způsob její přípravy a prostředek, který ji obsahuje
AU4065397A (en) * 1996-08-14 1998-03-06 Life Technologies, Inc. Stable compositions for nucleic acid amplification and sequencing
US6291164B1 (en) * 1996-11-22 2001-09-18 Invitrogen Corporation Methods for preventing inhibition of nucleic acid synthesis by pyrophosphate
US5861295A (en) * 1997-01-02 1999-01-19 Life Technologies, Inc. Nucleic acid-free thermostable enzymes and methods of production thereof
US6306588B1 (en) * 1997-02-07 2001-10-23 Invitrogen Corporation Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
AU7100198A (en) * 1997-04-03 1998-10-22 Life Technologies, Inc. Compositions and methods for reverse transcriptase-polymerase chain reaction (rt-pcr)
US6030814A (en) * 1997-04-21 2000-02-29 Epicentre Technologies Corporation Reverse transcription method
CN1259957B (zh) * 1997-04-22 2012-08-22 茵维特罗根公司 产生由多个亚单位组成的aslv逆转录酶的方法
US6140086A (en) * 1997-08-15 2000-10-31 Fox; Donna K. Methods and compositions for cloning nucleic acid molecules
DE19810879A1 (de) * 1998-03-13 1999-09-16 Roche Diagnostics Gmbh Polymerasenchimären
KR100269979B1 (ko) * 1998-04-15 2000-11-01 박한오 써무스 필리포미스로부터 분리된 내열성 dna 중합효소의 유전자 및 그로부터 유추되는 아미노산 서열
US7074556B2 (en) * 1999-03-02 2006-07-11 Invitrogen Corporation cDNA synthesis improvements
US6630333B1 (en) * 1999-03-23 2003-10-07 Invitrogen Corporation Substantially pure reverse transriptases and methods of production thereof
AU776129B2 (en) * 1999-05-21 2004-08-26 Invitrogen Corporation Compositions and methods for labeling of nucleic acid molecules
US6632645B1 (en) * 2000-03-02 2003-10-14 Promega Corporation Thermophilic DNA polymerases from Thermoactinomyces vulgaris
JP5148799B2 (ja) * 2000-03-15 2013-02-20 ライフ テクノロジーズ コーポレーション 高忠実度逆転写酵素およびその使用
JP2004521606A (ja) * 2000-05-24 2004-07-22 サード・ウェーブ・テクノロジーズ・インク Rnaの検出法
US7078208B2 (en) * 2000-05-26 2006-07-18 Invitrogen Corporation Thermostable reverse transcriptases and uses thereof
EP1301205A1 (en) * 2000-07-12 2003-04-16 Invitrogen Corporation High fidelity polymerases and uses thereof
US20030166170A1 (en) * 2002-01-17 2003-09-04 Invitrogen Corporation Methods of random mutagenesis and methods of modifying nucleic acids using translesion DNA polymerases

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