JP2005508613A5 - - Google Patents

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Publication number
JP2005508613A5
JP2005508613A5 JP2003510686A JP2003510686A JP2005508613A5 JP 2005508613 A5 JP2005508613 A5 JP 2005508613A5 JP 2003510686 A JP2003510686 A JP 2003510686A JP 2003510686 A JP2003510686 A JP 2003510686A JP 2005508613 A5 JP2005508613 A5 JP 2005508613A5
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JP
Japan
Prior art keywords
mycobacteria
tuberculosis
gene
nutrient
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003510686A
Other languages
English (en)
Japanese (ja)
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JP2005508613A (ja
Filing date
Publication date
Priority claimed from GB0116385A external-priority patent/GB0116385D0/en
Priority claimed from GB0123993A external-priority patent/GB0123993D0/en
Application filed filed Critical
Priority claimed from PCT/GB2002/003052 external-priority patent/WO2003004520A2/en
Publication of JP2005508613A publication Critical patent/JP2005508613A/ja
Publication of JP2005508613A5 publication Critical patent/JP2005508613A5/ja
Pending legal-status Critical Current

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JP2003510686A 2001-07-04 2002-07-04 潜伏中に発現されるマイコバクテリア抗原 Pending JP2005508613A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0116385A GB0116385D0 (en) 2001-07-04 2001-07-04 Mycobacterial antigens expressed during latency
GB0123993A GB0123993D0 (en) 2001-10-05 2001-10-05 Mycobacterial antigens expressed during latency
PCT/GB2002/003052 WO2003004520A2 (en) 2001-07-04 2002-07-04 Mycobacterial antigens expressed during latency

Publications (2)

Publication Number Publication Date
JP2005508613A JP2005508613A (ja) 2005-04-07
JP2005508613A5 true JP2005508613A5 (https=) 2005-12-22

Family

ID=26246282

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003510686A Pending JP2005508613A (ja) 2001-07-04 2002-07-04 潜伏中に発現されるマイコバクテリア抗原

Country Status (6)

Country Link
US (3) US7393540B2 (https=)
EP (2) EP1404706A2 (https=)
JP (1) JP2005508613A (https=)
AU (2) AU2002314358C1 (https=)
CA (1) CA2453173C (https=)
WO (1) WO2003004520A2 (https=)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9806093D0 (en) * 1998-03-20 1998-05-20 Taylor John Hermon Diagnostics and vaccines for mycobacterial infections of animals and humans
WO2003000721A2 (en) 2001-06-22 2003-01-03 Health Protection Agency Mycobacterial antigens expressed under low oxygen tension
JP2005508613A (ja) * 2001-07-04 2005-04-07 ヘルス プロテクション エージェンシー 潜伏中に発現されるマイコバクテリア抗原
GB0125535D0 (en) * 2001-10-24 2001-12-12 Microbiological Res Authority Mycobacterial genes down-regulated during latency
WO2004006952A2 (en) * 2002-07-13 2004-01-22 Statens Serum Institut Therapeutic tuberculosis vaccines
WO2004067718A2 (en) * 2003-01-24 2004-08-12 Emory University Necrosis-deficient mutants of tuberculosis bacteria
ES2231037B1 (es) 2003-10-31 2005-12-16 Archivel Technologies, Sl Agente inmunoterapico util para el tratamiento combinado de la tuberculosis en asociacion con otros farmacos.
AU2006229549B2 (en) * 2005-03-31 2011-04-07 Leiden University Medical Center Methods and means for diagnostics, prevention and treatment of Mycobacterium infections and tuberculosis disease
WO2006117538A2 (en) * 2005-04-29 2006-11-09 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
BRPI0612833A2 (pt) 2005-06-23 2010-11-30 Statens Seruminstitut composição imunogênica, vacina, composição farmacêutica, polipeptìdeo de fusão e uso das três primeiras
EP1910410B1 (en) 2005-07-01 2011-10-26 Forsyth Dental Infirmary for Children Tuberculosis antigen detection assays and vaccines
AU2006277828B2 (en) * 2005-08-09 2012-02-02 Hav Vaccines Limited Immunogenic constructs
US7601357B2 (en) * 2005-12-07 2009-10-13 University Of Central Florida Research Foundation, Inc. Targeting of long chain triacylglycerol hydrolase gene for tuberculosis treatment
CN101374964B (zh) * 2005-12-09 2013-07-17 贝勒研究院 外周血液白细胞转录模式的模块水平分析
EP1996732A4 (en) * 2006-03-02 2010-03-31 Uab Research Foundation RECOGNITION AND TREATMENT AND DISCOVERY OF REMEDIES AGAINST MYCOBACTERIAL DISEASES
ES2307402B1 (es) 2006-10-30 2009-09-30 Archivel Farma, S.L. Vacuna profilactica contra la tuberculosis.
US20110129817A1 (en) * 2009-11-30 2011-06-02 Baylor Research Institute Blood transcriptional signature of active versus latent mycobacterium tuberculosis infection
WO2009158521A2 (en) * 2008-06-25 2009-12-30 Baylor Research Institute Blood transcriptional signature of mycobacterium tuberculosis infection
US20100015171A1 (en) 2008-07-15 2010-01-21 Statens Serum Institute Vaccines comprising tb 10.4
ES2335177B1 (es) 2008-09-19 2011-02-28 Archivel Farma, S.L. Agente inmunoterapeutico apropiado para la profilaxis primaria de la tuberculosis.
CN102713629B (zh) 2009-11-20 2016-02-24 俄勒冈健康科学大学 用于检测结核分枝杆菌感染的方法
GB201008512D0 (en) 2010-05-21 2010-07-07 Health Prot Agency Mycobacterial antigen composition
ITRM20100411A1 (it) * 2010-07-23 2012-01-24 Massimo Amicosante Uso di sequenze amminoacidiche da mycobacterium tuberculosis o dei loro corrispondenti acidi nucleici per la diagnosi e la prevenzione di infezione tubercolare, relativo kit diagnostico e vaccino.
PL2661253T3 (pl) 2011-01-04 2017-08-31 Archivel Farma, Sl Preparat liposomowy odpowiedni do leczenia lub zapobiegania gruźlicy
EP2471511A1 (en) 2011-01-04 2012-07-04 Archivel Farma, SL Liposome formulation suitable for treating or preventing tuberculosis
US20140363465A1 (en) * 2011-04-04 2014-12-11 Beth Israel Deaconess Medical Center, Inc. Mycobacterial vaccine vectors and methods of using the same
JP2014531896A (ja) * 2011-08-30 2014-12-04 ザ ユーエービー リサーチ ファンデーション ヒト型結核菌ポリンおよび毒素ならびに関連方法
US10703784B2 (en) * 2011-09-30 2020-07-07 La Jolla Institute For Allergy And Immunology Antigens and epitopes derived from Mycobacterium tuberculosis
WO2013090897A1 (en) * 2011-12-15 2013-06-20 The Trustees Of The University Of Pennsylvania Using adaptive immunity to detect drug resistance
TWI638829B (zh) 2012-07-10 2018-10-21 法商傳斯堅公司 分枝桿菌抗原疫苗
US10197560B2 (en) 2013-06-27 2019-02-05 The Brigham And Women's Hospital, Inc. Methods and systems for determining M. tuberculosis infection
WO2015104380A1 (en) 2014-01-09 2015-07-16 Transgene Sa Fusion of heterooligomeric mycobacterial antigens
GB201400819D0 (en) * 2014-01-17 2014-03-05 Sec Dep For Health The Mycobacterial antigen composition
JP6781698B2 (ja) * 2014-08-15 2020-11-04 オックスフォード イミュノテック リミテッド 結核菌(Mycobacterium tuberculosis)タンパク質
CN111521820B (zh) * 2016-12-30 2023-06-16 首都医科大学附属北京胸科医院 结核分枝杆菌蛋白在制备诊断结核潜伏感染者和/或活动性肺结核产品中的用途
CN113302298B (zh) 2018-11-09 2025-02-25 银杏生物制品公司 罗汉果甙的生物合成
CN110129465B (zh) * 2019-05-22 2023-08-22 杭州优思达生物技术股份有限公司 一种海分枝杆菌核酸的快速检测方法及其试剂盒

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9024320D0 (en) 1990-11-08 1990-12-19 Univ London Treatment of uveitis
DE4221858A1 (de) 1992-07-03 1994-01-05 Becker Carl Chemie Gmbh Addukte von 0,0-Dialkyldithiophosphorsäuren an ungesättigte Verbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schmiermitteladditive
US6583266B1 (en) 1993-08-19 2003-06-24 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to mycobacterium tuberculosis and leprae for diagnostics and therapeutics
US5783386A (en) 1994-02-24 1998-07-21 Agresearch, New Zealand Pastoral Agriculture Research Institute Ltd. Mycobacteria virulence factors and a novel method for their identification
KR100551104B1 (ko) 1994-12-09 2006-02-09 임페리얼 컬리지 이노베이션스 리미티드 유전자의 동정
US6572865B1 (en) 1995-06-15 2003-06-03 University Of Victoria Innovation And Development Corporation Mycobacterium tuberculosis DNA sequences encoding immunostimulatory peptides and methods for using same
US5998194A (en) 1995-12-21 1999-12-07 Abbott Laboratories Polyketide-associated sugar biosynthesis genes
CA2197524A1 (en) 1996-02-22 1997-08-22 Bradley Stuart Dehoff Polyketide synthase genes
CA2249208A1 (en) 1996-03-27 1997-10-02 The Johns-Hopkins University Stationary phase, stress response sigma factor from mycobacterium tuberculosis, and regulation thereof
BR9712298A (pt) 1996-10-11 2000-10-24 Corixa Corp Polipeptìdeo, molécula de dna, vetor de expressão recombinante, célula hospedeira, processo para detectar infecção por m. tuberculosis em uma amostra biológica, kit diagnóstico, anticorpos monoclonal, e, policlonal, e, proteìna de fusão
US6555653B2 (en) 1997-05-20 2003-04-29 Corixa Corporation Compounds for diagnosis of tuberculosis and methods for their use
GB9711389D0 (en) 1997-06-04 1997-07-30 Univ Wales The Bacterial pheromones and uses therefor
EP1003870A1 (en) 1997-07-16 2000-05-31 Institut Pasteur A polynucleotide functionally coding for the lhp protein from mycobacterium tuberculosis, its biologically active derivative fragments, as well as methods using the same
WO1999010536A1 (en) 1997-08-22 1999-03-04 Yale University A process to study changes in gene expression in granulocytic cells
GB9723630D0 (en) 1997-11-07 1998-01-07 Stanford Rook Ltd M.vaccae preparation and its use
US6183957B1 (en) * 1998-04-16 2001-02-06 Institut Pasteur Method for isolating a polynucleotide of interest from the genome of a mycobacterium using a BAC-based DNA library application to the detection of mycobacteria
WO1999057130A1 (en) 1998-05-05 1999-11-11 Gene Logic, Inc. A process to study changes in gene expression in t lymphocytes
US6892139B2 (en) 1999-01-29 2005-05-10 The Regents Of The University Of California Determining the functions and interactions of proteins by comparative analysis
GB9904773D0 (en) * 1999-03-02 1999-04-28 Microbiological Res Authority Culture of mycobacteria
US6573361B1 (en) 1999-12-06 2003-06-03 Monsanto Technology Llc Antifungal proteins and methods for their use
US6613553B1 (en) * 2000-02-04 2003-09-02 St. Jude Children's Research Hospital Enoyl reductases and methods of use thereof
AU2002306849A1 (en) 2001-03-21 2002-10-08 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
WO2003000721A2 (en) 2001-06-22 2003-01-03 Health Protection Agency Mycobacterial antigens expressed under low oxygen tension
JP2005508613A (ja) 2001-07-04 2005-04-07 ヘルス プロテクション エージェンシー 潜伏中に発現されるマイコバクテリア抗原
GB0125535D0 (en) 2001-10-24 2001-12-12 Microbiological Res Authority Mycobacterial genes down-regulated during latency

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