JP2005506091A5 - - Google Patents

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Publication number
JP2005506091A5
JP2005506091A5 JP2003538385A JP2003538385A JP2005506091A5 JP 2005506091 A5 JP2005506091 A5 JP 2005506091A5 JP 2003538385 A JP2003538385 A JP 2003538385A JP 2003538385 A JP2003538385 A JP 2003538385A JP 2005506091 A5 JP2005506091 A5 JP 2005506091A5
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JP
Japan
Prior art keywords
chloro
formula
alkyl ester
acid alkyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2003538385A
Other languages
English (en)
Japanese (ja)
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JP2005506091A (ja
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Publication date
Priority claimed from DE10152113A external-priority patent/DE10152113C1/de
Application filed filed Critical
Publication of JP2005506091A publication Critical patent/JP2005506091A/ja
Publication of JP2005506091A5 publication Critical patent/JP2005506091A5/ja
Withdrawn legal-status Critical Current

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JP2003538385A 2001-10-23 2002-10-14 酵素的還元による(r)−および(s)−8−クロロ−6−ヒドロキシ−オクタン酸アルキルエステルの製造方法 Withdrawn JP2005506091A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10152113A DE10152113C1 (de) 2001-10-23 2001-10-23 Verfahren zur Herstellung von (R)- und (S)-8-Chlor-6-hydroxy-octansäurealkylestern durch enzymatische Reduktion
PCT/EP2002/011470 WO2003035885A1 (de) 2001-10-23 2002-10-14 Verfahren zur herstellung von (r)- und (s)-8-chlor-6-hydroxy-octansäurealkylestern durch enzymatische reduktion

Publications (2)

Publication Number Publication Date
JP2005506091A JP2005506091A (ja) 2005-03-03
JP2005506091A5 true JP2005506091A5 (https=) 2005-12-22

Family

ID=7703317

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003538385A Withdrawn JP2005506091A (ja) 2001-10-23 2002-10-14 酵素的還元による(r)−および(s)−8−クロロ−6−ヒドロキシ−オクタン酸アルキルエステルの製造方法

Country Status (5)

Country Link
US (1) US7157253B2 (https=)
EP (1) EP1440158A1 (https=)
JP (1) JP2005506091A (https=)
DE (1) DE10152113C1 (https=)
WO (1) WO2003035885A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012017026A1 (de) 2012-08-28 2014-03-06 Forschungszentrum Jülich GmbH Sensor für NADP(H) und Entwicklung von Alkoholdehydrogenasen
CN106164260B (zh) 2015-03-04 2019-10-01 华东理工大学 一种假丝酵母羰基还原酶及用于制备(r)-6-羟基-8-氯辛酸酯的方法
CN106083811B (zh) * 2016-06-14 2019-02-05 苏州富士莱医药股份有限公司 (R)-α-硫辛酸的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4037440A1 (de) * 1990-11-24 1992-05-27 Basf Ag Verfahren zur herstellung von (6s)-6,8-dihydroxyoctansaeureestern
DE19533882A1 (de) 1995-09-13 1997-03-20 Dresden Arzneimittel Herstellung und Verwendung der reinen Enantiomere der 8-Halogen-6-hydroxyoctansäuren, ihrer Alkylester und ihrer Salze mit reinen Enantiomeren des alpha-Methylbenzylamins
JP4012299B2 (ja) * 1998-02-25 2007-11-21 ダイセル化学工業株式会社 ハロゲン置換を含む光学活性アルコールの製造方法
DE10056025A1 (de) * 2000-07-27 2002-02-07 Asta Medica Ag Verfahren zur enantioselektiven Reduktion von 8-Chlor-6oxo-octansäurealkylestern
WO2002010422A1 (de) 2000-07-27 2002-02-07 Viatris Gmbh & Co. Kg Verfahren zur enantioselektiven reduktion von 8-chlor-6-oxo-octansäurealkylestern

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