JP2005503434A - ３−デスオキシ−ビタミンｄ３類似体 - Google Patents
３−デスオキシ−ビタミンｄ３類似体 Download PDFInfo
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- JP2005503434A JP2005503434A JP2003530656A JP2003530656A JP2005503434A JP 2005503434 A JP2005503434 A JP 2005503434A JP 2003530656 A JP2003530656 A JP 2003530656A JP 2003530656 A JP2003530656 A JP 2003530656A JP 2005503434 A JP2005503434 A JP 2005503434A
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- OGBMKVWORPGQRR-UMXFMPSGSA-N teriparatide Chemical compound C([C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CNC=N1 OGBMKVWORPGQRR-UMXFMPSGSA-N 0.000 description 1
- 230000004797 therapeutic response Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 210000003371 toe Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 231100000816 toxic dose Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 210000000623 ulna Anatomy 0.000 description 1
- 230000000450 urinary calcium excretion Effects 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 210000000707 wrist Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32387001P | 2001-09-21 | 2001-09-21 | |
| US32395701P | 2001-09-21 | 2001-09-21 | |
| PCT/EP2002/010233 WO2003027065A1 (en) | 2001-09-21 | 2002-09-12 | 3-desoxy-vitamin d3 analog esters |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005503434A true JP2005503434A (ja) | 2005-02-03 |
| JP2005503434A5 JP2005503434A5 (pt) | 2005-12-08 |
Family
ID=26984180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003530656A Pending JP2005503434A (ja) | 2001-09-21 | 2002-09-12 | ３−デスオキシ−ビタミンｄ３類似体 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1430026A1 (pt) |
| JP (1) | JP2005503434A (pt) |
| KR (1) | KR100628586B1 (pt) |
| CN (1) | CN1285573C (pt) |
| AU (1) | AU2002338672B2 (pt) |
| BR (1) | BR0212719A (pt) |
| CA (1) | CA2459789A1 (pt) |
| MX (1) | MXPA04002640A (pt) |
| PA (1) | PA8554901A1 (pt) |
| PE (1) | PE20030429A1 (pt) |
| PL (1) | PL370352A1 (pt) |
| RU (1) | RU2296121C2 (pt) |
| UY (1) | UY27448A1 (pt) |
| WO (1) | WO2003027065A1 (pt) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006503880A (ja) * | 2002-10-23 | 2006-02-02 | レオ・ファーマ・アクティーゼルスカブ | ビタミンｄ類似体、該類似体を含んで成る組成物およびその使用 |
| JP2008514621A (ja) * | 2004-09-24 | 2008-05-08 | ビオクセル エッセ ピ ア | ２０−シクロアルキル，２６，２７−アルキル／ハロアルキル−ビタミンｄ３化合物及びその使用方法 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005303773A1 (en) | 2004-11-12 | 2006-05-18 | Bioxell Spa | Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer |
| CN102124301B (zh) | 2008-08-22 | 2014-04-02 | Nxp股份有限公司 | 基于位置的服务 |
| CN110339205B (zh) * | 2019-08-19 | 2021-08-24 | 山东德信生物科技有限公司 | 富氢水组合物在抑制六价铬诱导的df-1细胞内质网应激及自噬中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG70010A1 (en) * | 1996-05-23 | 2000-01-25 | Hoffmann La Roche | Fluorinated vitamin d3 analogs |
| JP4219553B2 (ja) * | 1997-09-08 | 2009-02-04 | エフ．ホフマン−ラ ロシュ アーゲー | １，３−ジヒドロキシ−２０，２０−ジアルキル−ビタミンｄ３類似体 |
| US6331642B1 (en) * | 1999-07-12 | 2001-12-18 | Hoffmann-La Roche Inc. | Vitamin D3 analogs |
-
2002
- 2002-09-12 CA CA002459789A patent/CA2459789A1/en not_active Abandoned
- 2002-09-12 CN CNB028185285A patent/CN1285573C/zh not_active Expired - Fee Related
- 2002-09-12 MX MXPA04002640A patent/MXPA04002640A/es active IP Right Grant
- 2002-09-12 RU RU2004112217/04A patent/RU2296121C2/ru not_active IP Right Cessation
- 2002-09-12 PL PL02370352A patent/PL370352A1/xx not_active Application Discontinuation
- 2002-09-12 WO PCT/EP2002/010233 patent/WO2003027065A1/en not_active Application Discontinuation
- 2002-09-12 AU AU2002338672A patent/AU2002338672B2/en not_active Ceased
- 2002-09-12 KR KR1020047004110A patent/KR100628586B1/ko not_active IP Right Cessation
- 2002-09-12 JP JP2003530656A patent/JP2005503434A/ja active Pending
- 2002-09-12 BR BR0212719-9A patent/BR0212719A/pt not_active IP Right Cessation
- 2002-09-12 EP EP02777075A patent/EP1430026A1/en not_active Withdrawn
- 2002-09-18 PA PA20028554901A patent/PA8554901A1/es unknown
- 2002-09-19 PE PE2002000921A patent/PE20030429A1/es not_active Application Discontinuation
- 2002-09-20 UY UY27448A patent/UY27448A1/es not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006503880A (ja) * | 2002-10-23 | 2006-02-02 | レオ・ファーマ・アクティーゼルスカブ | ビタミンｄ類似体、該類似体を含んで成る組成物およびその使用 |
| JP2008514621A (ja) * | 2004-09-24 | 2008-05-08 | ビオクセル エッセ ピ ア | ２０−シクロアルキル，２６，２７−アルキル／ハロアルキル−ビタミンｄ３化合物及びその使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002338672B2 (en) | 2006-03-09 |
| WO2003027065A1 (en) | 2003-04-03 |
| BR0212719A (pt) | 2004-08-03 |
| CA2459789A1 (en) | 2003-04-03 |
| KR20040035853A (ko) | 2004-04-29 |
| PA8554901A1 (es) | 2003-12-10 |
| CN1285573C (zh) | 2006-11-22 |
| CN1556795A (zh) | 2004-12-22 |
| RU2296121C2 (ru) | 2007-03-27 |
| EP1430026A1 (en) | 2004-06-23 |
| PE20030429A1 (es) | 2003-05-15 |
| UY27448A1 (es) | 2003-03-31 |
| PL370352A1 (en) | 2005-05-16 |
| MXPA04002640A (es) | 2004-06-07 |
| RU2004112217A (ru) | 2005-07-10 |
| KR100628586B1 (ko) | 2006-09-26 |
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