JP2005502621A5 - - Google Patents

Download PDF

Info

Publication number
JP2005502621A5
JP2005502621A5 JP2003510107A JP2003510107A JP2005502621A5 JP 2005502621 A5 JP2005502621 A5 JP 2005502621A5 JP 2003510107 A JP2003510107 A JP 2003510107A JP 2003510107 A JP2003510107 A JP 2003510107A JP 2005502621 A5 JP2005502621 A5 JP 2005502621A5
Authority
JP
Japan
Prior art keywords
hydrogen atom
hydroxy
alkyl
antibacterial agent
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003510107A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005502621A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2002/006670 external-priority patent/WO2003004098A1/en
Publication of JP2005502621A publication Critical patent/JP2005502621A/ja
Publication of JP2005502621A5 publication Critical patent/JP2005502621A5/ja
Pending legal-status Critical Current

Links

JP2003510107A 2001-07-06 2002-07-02 インターロイキン２阻害剤および抗菌剤を含む局所投与用組成物 Pending JP2005502621A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30314801P 2001-07-06 2001-07-06
PCT/JP2002/006670 WO2003004098A1 (en) 2001-07-06 2002-07-02 Composition for topical administration comprising an interleukin-2 inhibitor and an antimicrobial agent

Publications (2)

Publication Number Publication Date
JP2005502621A JP2005502621A (ja) 2005-01-27
JP2005502621A5 true JP2005502621A5 (https=) 2006-01-05

Family

ID=23170731

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003510107A Pending JP2005502621A (ja) 2001-07-06 2002-07-02 インターロイキン２阻害剤および抗菌剤を含む局所投与用組成物

Country Status (9)

Country Link
US (2) US7033604B2 (https=)
EP (1) EP1406700A1 (https=)
JP (1) JP2005502621A (https=)
KR (1) KR20040019034A (https=)
CN (1) CN1259049C (https=)
AR (1) AR036127A1 (https=)
CA (1) CA2452372A1 (https=)
NZ (1) NZ530845A (https=)
WO (1) WO2003004098A1 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004098A1 (en) * 2001-07-06 2003-01-16 Sucampo Ag Composition for topical administration comprising an interleukin-2 inhibitor and an antimicrobial agent
CA2495103A1 (en) * 2002-08-09 2004-02-19 Sucampo Pharmaceuticals, Inc. Pharmaceutical compositions comprising fk506 derivatives and their use for the treatment of allergic diseases
US7354574B2 (en) 2002-11-07 2008-04-08 Advanced Ocular Systems Limited Treatment of ocular disease
GB0307862D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Pharmaceutical composition
US7083802B2 (en) 2003-07-31 2006-08-01 Advanced Ocular Systems Limited Treatment of ocular disease
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
KR20060085246A (ko) * 2003-09-18 2006-07-26 마커사이트, 인코포레이티드 경공막 전달
US7087237B2 (en) * 2003-09-19 2006-08-08 Advanced Ocular Systems Limited Ocular solutions
US7083803B2 (en) 2003-09-19 2006-08-01 Advanced Ocular Systems Limited Ocular solutions
KR101140039B1 (ko) * 2004-01-26 2012-05-02 (주)아모레퍼시픽 진세노사이드 ｆ1 또는 화합물 ｋ를 함유하는 피부외용제조성물
US7151085B2 (en) * 2004-11-15 2006-12-19 Allergan, Inc. Therapeutic methods using cyclosporine components
US7135455B2 (en) * 2004-11-15 2006-11-14 Allergan, Inc Methods for the therapeutic use of cyclosporine components
US8663639B2 (en) * 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
DK1848431T3 (en) * 2005-02-09 2016-04-18 Santen Pharmaceutical Co Ltd LIQUID FORMULATIONS FOR TREATMENT OF DISEASES OR CONDITIONS
KR20140093764A (ko) 2006-02-09 2014-07-28 산텐 세이야꾸 가부시키가이샤 안정한 제제와 그 제조 및 사용 방법
ES2563288T3 (es) 2006-03-23 2016-03-14 Santen Pharmaceutical Co., Ltd Rapamicina en dosis bajas para el tratamiento de enfermedades relacionadas con la permeabilidad vascular
CA2654510C (en) 2006-06-16 2015-03-17 Regeneron Pharmaceuticals, Inc. Vegf antagonist formulations suitable for intravitreal administration
US20080265343A1 (en) * 2007-04-26 2008-10-30 International Business Machines Corporation Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
ES2667945T3 (es) 2007-10-08 2018-05-16 Aurinia Pharmaceuticals Inc. Composiciones oftálmicas que comprenden inhibidores de calcineurina o Inhibidores de mTOR
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
EP2440185B1 (en) * 2009-06-09 2015-04-08 Aurinia Pharmaceuticals Inc. Topical drug delivery systems for ophthalmic use
EP2665486B1 (en) 2011-01-18 2019-12-25 Bioniz, LLC Compositions for modulating gamma-c-cytokine activity
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
GB2516138C (en) * 2013-04-09 2015-12-09 Cresset Biomolecular Discovery Ltd The treatment of inflammatory disorders
US9959384B2 (en) 2013-12-10 2018-05-01 Bioniz, Llc Methods of developing selective peptide antagonists
WO2017062685A1 (en) 2015-10-09 2017-04-13 Bioniz, Llc Modulating gamma - c -cytokine activity
WO2017096031A1 (en) 2015-12-03 2017-06-08 Regeneron Pharmaceuticals, Inc. Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-vegf
US12600757B2 (en) 2017-04-07 2026-04-14 Bioniz Therapeutics, Inc. Peptides inhibiting gamma-c-cytokine activity and methods of use
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
US11519020B2 (en) 2018-05-25 2022-12-06 Regeneron Pharmaceuticals, Inc. Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF
CA3137971A1 (en) 2019-05-03 2020-11-12 Bioniz, Llc Modulating the effects of gamma-c-cytokine signaling for the treatment of alopecia and alopecia associated disorders

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117118A (en) 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
DE2907460A1 (de) 1978-03-07 1979-09-13 Sandoz Ag Neue resorbierbare galenische kompositionen
US4215199A (en) 1978-06-05 1980-07-29 Sandoz Ltd. Antibiotic production
SE448386B (sv) 1978-10-18 1987-02-16 Sandoz Ag Nya cyklosporinderivat, forfarande for framstellning av dem samt farmaceutisk komposition innehallande dem
ES2099112T3 (es) 1990-09-04 1997-05-16 Fujisawa Pharmaceutical Co Pomadas que contienen un compuesto triciclico.
US5143918A (en) * 1990-10-11 1992-09-01 Merck & Co., Inc. Halomacrolides and derivatives having immunosuppressive activity
US5348966A (en) * 1990-10-24 1994-09-20 Fujisawa Pharmaceutical Co., Ltd. Method for treating pyoderma and Sezary's syndrome using FK 506 and related compounds
DE69231644T2 (de) 1991-04-26 2001-05-23 Fujisawa Pharmaceutical Co., Ltd. Verwendung von makrolid-verbindungen gegen augenerkrankungen
IT1253711B (it) * 1991-12-17 1995-08-23 Alfa Wassermann Spa Formulazioni farmaceutiche vaginali contenenti rifaximin e loro uso nel trattamento delle infezioni vaginali
GB9221220D0 (en) 1992-10-09 1992-11-25 Sandoz Ag Organic componds
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
JPH06345646A (ja) * 1993-06-08 1994-12-20 Fujisawa Pharmaceut Co Ltd ローション剤
US5489435A (en) * 1993-07-06 1996-02-06 Ratcliff; Perry A. Composition for treatment of abnormal conditions of the epithelium of bodily orifices
CA2194049A1 (en) * 1994-06-28 1996-01-11 Georgi Stankov Novel clinical uses of polyene macrolides
US6087358A (en) * 1995-06-26 2000-07-11 Pathogenesis Corporation Nitro-[2,1-b]imidazopyran compounds and antibacterial uses thereof
AU2441397A (en) * 1996-04-05 1997-10-29 Family Health International Use of macrolide antibiotics for nonsurgical female sterilization and endometrial ablation
US5929086A (en) * 1996-05-10 1999-07-27 Pharmacia & Upjohn Company Topical administration of antimicrobial agents for the treatment of systemic bacterial diseases
US6248776B1 (en) * 1997-08-26 2001-06-19 Bioavailability Systems, L.L.C. Anti-first-pass effect compounds
US5912255A (en) * 1998-02-27 1999-06-15 Bussell; Letantia Topical fluoroquinolone antibiotics combined with benzoyl peroxide
US6312715B1 (en) * 1998-05-01 2001-11-06 3M Innovative Properties Company Adhesive microsphere drug delivery composition
AUPP437698A0 (en) * 1998-06-30 1998-07-23 Baumgart, Karl Methods for treatment of coronary, carotid and other vascular disease
US6864232B1 (en) * 1998-12-24 2005-03-08 Sucampo Ag Agent for treating visual cell function disorder
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6174859B1 (en) * 1999-04-06 2001-01-16 J & D Sciences, Inc. Method of treatment
US7063857B1 (en) * 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
WO2000066122A1 (en) 1999-04-30 2000-11-09 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
JP2003510263A (ja) * 1999-09-24 2003-03-18 アルコン，インコーポレイテッド シプロフロキサシンおよびデキサメタゾンを含有する局所用懸濁処方物
AR033151A1 (es) 2001-04-12 2003-12-03 Sucampo Pharmaceuticals Inc Agente para el tratamiento oftalmico topico de las enfermedades inflamatorias oculares
WO2003004098A1 (en) 2001-07-06 2003-01-16 Sucampo Ag Composition for topical administration comprising an interleukin-2 inhibitor and an antimicrobial agent
US20030114416A1 (en) * 2001-08-14 2003-06-19 Pharmacia Corporation Method and compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate
US20050070468A1 (en) * 2001-11-21 2005-03-31 Sucampo Ag Use of fk506 and analogues for treating allergic diseases
EP1530475A2 (en) * 2002-07-17 2005-05-18 Warner-Lambert Company LLC Pharmaceutical compositions comprising an allosteric carboxylic inhibitor of matrix metalloproteinase-13 and a selective inhibitor of cyclooxygenase-2
CA2495103A1 (en) * 2002-08-09 2004-02-19 Sucampo Pharmaceuticals, Inc. Pharmaceutical compositions comprising fk506 derivatives and their use for the treatment of allergic diseases
WO2004062669A1 (en) * 2003-01-16 2004-07-29 Sucampo Ag Use of a macrolide compound for treating dry eye

Similar Documents

Publication Publication Date Title
JP2005502621A5 (https=)
AR036127A1 (es) Composicion para administracion topica que comprende un inhibidor de interleucina 2 y un agente antimicrobiano y uso de estos ultimos para preparar dicha composicion
MY143564A (en) Quinoline derivatives and their use as mycobacterial inhibitors
NO20066041L (no) Anvendelse av substituerte kinolinderivater for behandlingen og legemiddelresistente mykobakterielle sykdommer
MX2010006182A (es) Derivados de isoxazolo-piridazina.
AR027464A1 (es) Oxamidas que son inhibidores de la inosina monofosfato deshidrogenasa (impdh)
JP2008526999A5 (https=)
CA2656716C (fr) Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
HUP0303756A2 (hu) 1-Aril- vagy 1-alkilszulfonil-heterociklobenzazolok és eljárás ezek elõállítására és ezeket tartalmazó gyógyszerkészítmények
JP2011505347A5 (https=)
JP2010539179A5 (https=)
JP2010501478A5 (https=)
CA2475619A1 (en) Piperidine derivatives
RU2008145714A (ru) Пуриновые производные в качестве активатора аденозинового рецептора
RU2002100058A (ru) Кристаллические производные 1-метилкарбапенема
JP2018522927A5 (https=)
JP2004529928A5 (https=)
AR065297A1 (es) Formulaciones biodisponibles de compuestos heterociclicos
JP2005536531A5 (https=)
ZA202203107B (en) Azaindole carboxamide compounds for the treatment of mycobacterial infections
JP2007527904A5 (https=)
JP2005529935A5 (https=)
ATE457306T1 (de) 4-aryl substituierte chinole und analoga als therapeutische wirkstoffe
WO2005023792A3 (en) Macrocyclic compounds useful as pharmaceuticals
CA2487252A1 (en) Esters in position 20 of camptothecins