JP2005500366A5 - - Google Patents
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- Publication number
- JP2005500366A5 JP2005500366A5 JP2003518522A JP2003518522A JP2005500366A5 JP 2005500366 A5 JP2005500366 A5 JP 2005500366A5 JP 2003518522 A JP2003518522 A JP 2003518522A JP 2003518522 A JP2003518522 A JP 2003518522A JP 2005500366 A5 JP2005500366 A5 JP 2005500366A5
- Authority
- JP
- Japan
- Prior art keywords
- substituent
- hydrocarbon group
- aliphatic hydrocarbon
- group
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 125000001424 substituent group Chemical group 0.000 claims description 49
- 125000001931 aliphatic group Chemical group 0.000 claims description 28
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 17
- 125000002029 aromatic hydrocarbon group Chemical group 0.000 claims description 12
- 125000000392 cycloalkenyl group Chemical group 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- 239000000839 emulsion Substances 0.000 claims description 8
- 125000003118 aryl group Chemical group 0.000 claims description 6
- 125000005843 halogen group Chemical group 0.000 claims description 6
- 125000001183 hydrocarbyl group Chemical group 0.000 claims description 6
- 150000003904 phospholipids Chemical class 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 229940002612 prodrug Drugs 0.000 claims description 4
- 239000000651 prodrug Substances 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- 125000000129 anionic group Chemical group 0.000 claims description 3
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 description 5
- 230000001548 androgenic effect Effects 0.000 description 4
- 125000004429 atom Chemical group 0.000 description 4
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 3
- 125000000217 alkyl group Chemical group 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 150000001925 cycloalkenes Chemical class 0.000 description 2
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 229940125904 compound 1 Drugs 0.000 description 1
- 229940126214 compound 3 Drugs 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 230000016396 cytokine production Effects 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2001/024487 WO2003013513A1 (en) | 2001-08-03 | 2001-08-03 | Stable emulsion composition |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005500366A JP2005500366A (ja) | 2005-01-06 |
| JP2005500366A5 true JP2005500366A5 (https=) | 2008-09-18 |
| JP5137289B2 JP5137289B2 (ja) | 2013-02-06 |
Family
ID=21742754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003518522A Expired - Fee Related JP5137289B2 (ja) | 2001-08-03 | 2001-08-03 | 安定な乳化組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7960416B2 (https=) |
| EP (1) | EP1420783A4 (https=) |
| JP (1) | JP5137289B2 (https=) |
| CA (1) | CA2456029C (https=) |
| WO (1) | WO2003013513A1 (https=) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
| IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
| US8486376B2 (en) | 2002-10-25 | 2013-07-16 | Foamix Ltd. | Moisturizing foam containing lanolin |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
| US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
| US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
| ES2532906T5 (es) | 2002-10-25 | 2022-03-23 | Foamix Pharmaceuticals Ltd | Espuma cosmética y farmacéutica |
| US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
| US20080138296A1 (en) * | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
| US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
| US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
| US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
| US7416756B2 (en) | 2003-09-10 | 2008-08-26 | Eastman Chemical Company | Process for the recovery of a phytolipid composition |
| US20050239745A1 (en) * | 2004-03-03 | 2005-10-27 | Ophthalmic Research Associates, Inc. | Novel topical ophthalmic formulations |
| JP4954085B2 (ja) | 2004-12-06 | 2012-06-13 | メディシノバ， インコーポレイテッド | 神経障害性疼痛及びその関連する症状を治療するためのイブジラスト |
| MY147790A (en) * | 2005-04-28 | 2013-01-31 | Takeda Pharmaceutical | Stable emulsion composition |
| US8187659B2 (en) * | 2006-05-02 | 2012-05-29 | Jerry Robertson Real Estate Llc | Solid medicament dosage form consumption aid |
| WO2007132825A1 (ja) * | 2006-05-15 | 2007-11-22 | Takeda Pharmaceutical Company Limited | 医薬 |
| US20070275053A1 (en) * | 2006-05-26 | 2007-11-29 | Luise Anneliese Lenk | Anti-stick formula delivered by spray process to facilitate swallowing of solid object, such as pill, tablet capsule or caplet. |
| ATE549014T1 (de) | 2006-09-05 | 2012-03-15 | Q P Corp | Prostaglandin-fettemulsion, verfahren zu ihrer herstellung, verfahren zu ihrer stabilisierung und emulgierendes mittel |
| US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| US20080181876A1 (en) * | 2007-01-30 | 2008-07-31 | Johnson Kirk W | Methods for treating acute and subchronic pain |
| US20080234376A1 (en) | 2007-03-21 | 2008-09-25 | Taiwan Liposome Company (A Taiwan Corporation) | Emulsion composition comprising prostaglandin e1 |
| WO2008137012A1 (en) * | 2007-05-03 | 2008-11-13 | Avigen, Inc. | Use of a glial attenuator to prevent amplified pain responses caused by glial priming |
| US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| RU2418601C2 (ru) * | 2007-10-10 | 2011-05-20 | Закрытое акционерное общество "Эвалар" | Средство, обладающее гепатопротекторным, детоксицирующим и регенерирующим действием |
| US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
| WO2009072007A2 (en) | 2007-12-07 | 2009-06-11 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
| US8518376B2 (en) | 2007-12-07 | 2013-08-27 | Foamix Ltd. | Oil-based foamable carriers and formulations |
| EP2242476A2 (en) | 2008-01-14 | 2010-10-27 | Foamix Ltd. | Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses |
| WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
| WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
| WO2011064631A1 (en) | 2009-10-02 | 2011-06-03 | Foamix Ltd. | Surfactant-free, water-free, foamable compositions and breakable foams and their uses |
| US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
| TWI481401B (zh) | 2010-01-27 | 2015-04-21 | Takeda Pharmaceutical | 藥劑 |
| GB2477590A (en) * | 2010-02-05 | 2011-08-10 | Biocopea Ltd | A non-steroidal anti-inflammatory drug (NSAID) formulation comprising a lipid carrier |
| US9504664B2 (en) | 2010-10-29 | 2016-11-29 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
| US9737500B2 (en) | 2010-10-29 | 2017-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
| US10695431B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| US9308213B2 (en) | 2010-10-29 | 2016-04-12 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US9744132B2 (en) | 2010-10-29 | 2017-08-29 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
| US9271950B2 (en) | 2010-10-29 | 2016-03-01 | Infirst Healthcare Limited | Compositions for treating chronic inflammation and inflammatory diseases |
| US11202831B2 (en) | 2010-10-29 | 2021-12-21 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
| US8895537B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating cardiovascular diseases |
| US10695432B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| US11224659B2 (en) | 2010-10-29 | 2022-01-18 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
| US11730709B2 (en) | 2010-10-29 | 2023-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
| WO2012075534A1 (en) | 2010-12-10 | 2012-06-14 | Ns Technologies Pty Ltd | Methods for forming miniemulsions and use thereof for delivering bioactive agents |
| EP3247384B1 (en) | 2015-01-14 | 2023-10-04 | The Regents of the University of Colorado, a body corporate | In vitro method of diagnosis of type 1 diabetes with insulin mimotopes |
| CA2980940C (en) * | 2015-05-28 | 2021-01-12 | The Regents Of The University Of Colorado, A Body Corporate | Methods of preventing and treating autoimmunity |
| WO2017165508A1 (en) | 2016-03-24 | 2017-09-28 | Im Therapeutics | Methods of treating autoimmune disease |
| US10398641B2 (en) | 2016-09-08 | 2019-09-03 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
| US11052060B2 (en) | 2018-02-12 | 2021-07-06 | The Regents Of The University Of Colorado, A Body Corporate | Compounds and methods for treating autoimmunity |
| US11013707B2 (en) | 2018-03-23 | 2021-05-25 | The Regents Of The University Of Colorado, A Body Corporate | Administration of oral methyldopa |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2844756B2 (ja) * | 1989-12-01 | 1999-01-06 | 日本新薬株式会社 | 脂肪乳剤 |
| JPH04173736A (ja) * | 1990-11-06 | 1992-06-22 | Nippon Shinyaku Co Ltd | 乳化剤 |
| AU665931B2 (en) * | 1990-11-06 | 1996-01-25 | Nippon Shinyaku Co. Ltd. | Lyophilized preparation and production thereof |
| US5576016A (en) | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
| FI963297L (fi) | 1994-02-25 | 1996-10-18 | Takeda Chemical Industries Ltd | Antifungaalisia triatsolijohdannaisia sisältävät emulsiot |
| JPH0827018A (ja) * | 1994-07-22 | 1996-01-30 | Sanwa Kagaku Kenkyusho Co Ltd | 生理活性ペプチド又は蛋白質を含有する薬剤組成物 |
| RU2214398C2 (ru) * | 1998-03-09 | 2003-10-20 | Такеда Кемикал Индастриз, Лтд. | Производное циклоалкена, способ его получения (варианты), фармацевтическая композиция, способ ингибирования, способ профилактики или лечения |
| KR100784752B1 (ko) | 2000-02-04 | 2007-12-13 | 다케다 야쿠힌 고교 가부시키가이샤 | 안정한 에멀젼 조성물 |
| JP4863553B2 (ja) * | 2000-02-04 | 2012-01-25 | 武田薬品工業株式会社 | 安定な乳化組成物 |
-
2001
- 2001-08-03 CA CA2456029A patent/CA2456029C/en not_active Expired - Fee Related
- 2001-08-03 WO PCT/US2001/024487 patent/WO2003013513A1/en not_active Ceased
- 2001-08-03 JP JP2003518522A patent/JP5137289B2/ja not_active Expired - Fee Related
- 2001-08-03 EP EP01965853A patent/EP1420783A4/en not_active Withdrawn
- 2001-08-03 US US10/485,637 patent/US7960416B2/en not_active Expired - Fee Related
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