JP2005140790A - 粒子を含む液体から液状成分を分離するための微細構造型分離装置および分離方法 - Google Patents

粒子を含む液体から液状成分を分離するための微細構造型分離装置および分離方法 Download PDF

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Publication number
JP2005140790A
JP2005140790A JP2004324376A JP2004324376A JP2005140790A JP 2005140790 A JP2005140790 A JP 2005140790A JP 2004324376 A JP2004324376 A JP 2004324376A JP 2004324376 A JP2004324376 A JP 2004324376A JP 2005140790 A JP2005140790 A JP 2005140790A
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Japan
Prior art keywords
separation
particles
microstructure
liquid
composite
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Ceased
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JP2004324376A
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English (en)
Japanese (ja)
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JP2005140790A5 (enExample
Inventor
Gert Blankenstein
ゲルト，ブランケンシュタイン
Claus Marquordt
マルクヴォルト クラウス
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Boehringer Ingelheim Microparts GmbH
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Steag Microparts GmbH
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Publication of JP2005140790A publication Critical patent/JP2005140790A/ja
Publication of JP2005140790A5 publication Critical patent/JP2005140790A5/ja
Ceased legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
    • B01F25/4317—Profiled elements, e.g. profiled blades, bars, pillars, columns or chevrons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
    • B01F25/4316—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor the baffles being flat pieces of material, e.g. intermeshing, fixed to the wall or fixed on a central rod
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2004324376A 2003-11-07 2004-11-08 粒子を含む液体から液状成分を分離するための微細構造型分離装置および分離方法 Ceased JP2005140790A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10352535A DE10352535A1 (de) 2003-11-07 2003-11-07 Mikrostrukturierte Trennvorrichtung und Verfahren zum Abtrennen von flüssigen Bestandteilen aus einer Partikel enthaltenden Flüssigkeit

Publications (2)

Publication Number Publication Date
JP2005140790A true JP2005140790A (ja) 2005-06-02
JP2005140790A5 JP2005140790A5 (enExample) 2007-11-01

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JP2004324376A Ceased JP2005140790A (ja) 2003-11-07 2004-11-08 粒子を含む液体から液状成分を分離するための微細構造型分離装置および分離方法

Country Status (5)

Country Link
US (1) US20050106756A1 (enExample)
EP (1) EP1531003B1 (enExample)
JP (1) JP2005140790A (enExample)
CN (1) CN100453182C (enExample)
DE (1) DE10352535A1 (enExample)

Cited By (16)

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JP2009109232A (ja) * 2007-10-26 2009-05-21 Josho Gakuen 固液分離機能を有する装置及びその製造方法
JP2010537203A (ja) * 2007-08-24 2010-12-02 アドヴァンスト リキッド ロジック インコーポレイテッド 液滴アクチュエータでのビーズ操作
JP2011508657A (ja) * 2007-07-11 2011-03-17 コーニング インコーポレイテッド プロセス強化マイクロ流体装置
JP2011513718A (ja) * 2008-02-27 2011-04-28 ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツング 血漿の分離装置
KR20130037073A (ko) * 2011-10-05 2013-04-15 삼성전자주식회사 유체 제어 장치 및 이를 사용하는 유체 제어 방법
JP2013524256A (ja) * 2010-04-15 2013-06-17 サイトゲン カンパニー リミテッド 微細流体装置及びこれを用いたターゲットの分離方法
KR101517091B1 (ko) 2012-05-10 2015-05-04 단국대학교 산학협력단 미세입자 분리장치 및 미세입자 분리수거방법
KR101768123B1 (ko) * 2010-12-03 2017-08-16 삼성전자주식회사 수력학 필터, 이를 구비한 필터링 장치 및 이에 의한 필터링 방법
JPWO2016084381A1 (ja) * 2014-11-28 2017-09-07 東洋製罐グループホールディングス株式会社 微細液送構造体、及び分析装置
KR101850852B1 (ko) 2016-01-08 2018-04-23 재단법인차세대융합기술연구원 미세유체채널장치 및 이의 사용방법
JP2021043208A (ja) * 2013-03-13 2021-03-18 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ 液体中の気泡形成を軽減するための方法および装置
JPWO2022070841A1 (enExample) * 2020-09-29 2022-04-07
USD962471S1 (en) 2013-03-13 2022-08-30 Abbott Laboratories Reagent container
USD978375S1 (en) 2013-03-13 2023-02-14 Abbott Laboratories Reagent container
US11712671B2 (en) 2013-03-13 2023-08-01 Abbott Laboratories Methods and apparatus to agitate a liquid
JPWO2023189095A1 (enExample) * 2022-03-28 2023-10-05

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WO2011078115A1 (ja) * 2009-12-25 2011-06-30 学校法人常翔学園 固液分離機能を有する装置、μ－ＴＡＳデバイス及び固液分離方法
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KR101911435B1 (ko) 2011-09-26 2018-10-25 삼성전자주식회사 유체 제어 장치, 이를 포함하는 필터 및 바이오칩
DE102011122579A1 (de) * 2011-12-29 2013-07-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum Trennen von Suspensions- oder Kolloidbestandteilen und Vorrichtung zum Trennen von Suspensions- oder Kolloidbestandteilen
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WO2017217563A1 (ko) 2016-06-13 2017-12-21 엘지전자 주식회사 디스플레이 장치 및 그를 포함하는 디스플레이 시스템
CN106311368B (zh) * 2016-07-29 2018-06-15 大连理工大学 一种用于微量进样器的液滴无损脱离装置
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JP2014147930A (ja) * 2007-07-11 2014-08-21 Corning Inc プロセス強化マイクロ流体装置
JP2011508657A (ja) * 2007-07-11 2011-03-17 コーニング インコーポレイテッド プロセス強化マイクロ流体装置
JP2020114585A (ja) * 2007-07-11 2020-07-30 コーニング インコーポレイテッド プロセス強化マイクロ流体装置
JP2018051553A (ja) * 2007-07-11 2018-04-05 コーニング インコーポレイテッド プロセス強化マイクロ流体装置
JP7049381B2 (ja) 2007-07-11 2022-04-06 コーニング インコーポレイテッド プロセス強化マイクロ流体装置
JP2010537203A (ja) * 2007-08-24 2010-12-02 アドヴァンスト リキッド ロジック インコーポレイテッド 液滴アクチュエータでのビーズ操作
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JP2013524256A (ja) * 2010-04-15 2013-06-17 サイトゲン カンパニー リミテッド 微細流体装置及びこれを用いたターゲットの分離方法
KR101768123B1 (ko) * 2010-12-03 2017-08-16 삼성전자주식회사 수력학 필터, 이를 구비한 필터링 장치 및 이에 의한 필터링 방법
KR20130037073A (ko) * 2011-10-05 2013-04-15 삼성전자주식회사 유체 제어 장치 및 이를 사용하는 유체 제어 방법
KR101890743B1 (ko) * 2011-10-05 2018-08-23 삼성전자주식회사 유체 제어 장치 및 이를 사용하는 유체 제어 방법
KR101517091B1 (ko) 2012-05-10 2015-05-04 단국대학교 산학협력단 미세입자 분리장치 및 미세입자 분리수거방법
USD1098486S1 (en) 2013-03-13 2025-10-14 Abbott Laboratories Container for a diagnostic analyzer
JP2021043208A (ja) * 2013-03-13 2021-03-18 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ 液体中の気泡形成を軽減するための方法および装置
JP7073470B2 (ja) 2013-03-13 2022-05-23 アボット・ラボラトリーズ 液体中の気泡形成を軽減するための方法および装置
USD962471S1 (en) 2013-03-13 2022-08-30 Abbott Laboratories Reagent container
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US11712671B2 (en) 2013-03-13 2023-08-01 Abbott Laboratories Methods and apparatus to agitate a liquid
US11738346B2 (en) 2013-03-13 2023-08-29 Abbott Laboratories Methods and apparatus to mitigate bubble formation in a liquid
USD1099356S1 (en) 2013-03-13 2025-10-21 Abbott Laboratories Reagent container
JPWO2016084381A1 (ja) * 2014-11-28 2017-09-07 東洋製罐グループホールディングス株式会社 微細液送構造体、及び分析装置
KR101850852B1 (ko) 2016-01-08 2018-04-23 재단법인차세대융합기술연구원 미세유체채널장치 및 이의 사용방법
JPWO2022070841A1 (enExample) * 2020-09-29 2022-04-07
JP7455339B2 (ja) 2020-09-29 2024-03-26 Nok株式会社 白血球捕捉デバイス
JP7729536B2 (ja) 2022-03-28 2025-08-26 国立大学法人茨城大学 白血球捕捉デバイス
WO2023189095A1 (ja) * 2022-03-28 2023-10-05 国立大学法人茨城大学 白血球捕捉デバイス
JPWO2023189095A1 (enExample) * 2022-03-28 2023-10-05

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