|
US6858409B1
(en)
|
1988-05-27 |
2005-02-22 |
Amgen Inc. |
Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
|
|
US5075222A
(en)
|
1988-05-27 |
1991-12-24 |
Synergen, Inc. |
Interleukin-1 inhibitors
|
|
US6159460A
(en)
*
|
1988-05-27 |
2000-12-12 |
Amgen Inc. |
Method for treating interleukin-1 mediated diseases
|
|
US6180134B1
(en)
*
|
1993-03-23 |
2001-01-30 |
Sequus Pharmaceuticals, Inc. |
Enhanced ciruclation effector composition and method
|
|
GB9509016D0
(en)
*
|
1995-05-03 |
1995-06-21 |
Royal Free Hosp School Med |
Tissue entrapment
|
|
US5919480A
(en)
*
|
1996-06-24 |
1999-07-06 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Liposomal influenza vaccine composition and method
|
|
EP0949931B1
(en)
|
1996-12-06 |
2008-08-27 |
Amgen Inc., |
Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases
|
|
US5827533A
(en)
*
|
1997-02-06 |
1998-10-27 |
Duke University |
Liposomes containing active agents aggregated with lipid surfactants
|
|
US6294170B1
(en)
|
1997-08-08 |
2001-09-25 |
Amgen Inc. |
Composition and method for treating inflammatory diseases
|
|
US7122636B1
(en)
|
1997-02-21 |
2006-10-17 |
Genentech, Inc. |
Antibody fragment-polymer conjugates and uses of same
|
|
BR9807464A
(pt)
|
1997-02-21 |
2000-05-09 |
Genentech Inc |
Conjugado, composição, molécula de ácido nucleico, vetor de expressão, célula hospedeira, método para produzir um polipeptìdeo e polipeptìdeo.
|
|
US6013253A
(en)
*
|
1997-08-15 |
2000-01-11 |
Amgen, Inc. |
Treatment of multiple sclerosis using consensus interferon and IL-1 receptor antagonist
|
|
US6468532B1
(en)
|
1998-01-22 |
2002-10-22 |
Genentech, Inc. |
Methods of treating inflammatory diseases with anti-IL-8 antibody fragment-polymer conjugates
|
|
US7005504B2
(en)
|
1998-01-22 |
2006-02-28 |
Genentech, Inc. |
Antibody fragment-peg conjugates
|
|
US6458355B1
(en)
|
1998-01-22 |
2002-10-01 |
Genentech, Inc. |
Methods of treating inflammatory disease with anti-IL-8 antibody fragment-polymer conjugates
|
|
US6593294B1
(en)
*
|
1998-04-27 |
2003-07-15 |
Opperbas Holding B.V. |
Pharmaceutical composition comprising Factor VIII and neutral liposomes
|
|
US8106098B2
(en)
|
1999-08-09 |
2012-01-31 |
The General Hospital Corporation |
Protein conjugates with a water-soluble biocompatible, biodegradable polymer
|
|
US7829074B2
(en)
|
2001-10-18 |
2010-11-09 |
Nektar Therapeutics |
Hydroxypatite-targeting poly(ethylene glycol) and related polymers
|
|
NZ528523A
(en)
*
|
2001-03-26 |
2006-03-31 |
Alza Corp |
Liposome composition for improved intracellular delivery of a therapeutic agent
|
|
PH12012502439A1
(en)
|
2001-06-26 |
2013-06-17 |
Amgen Inc |
Antibodies to opgl
|
|
AU2003220011B2
(en)
*
|
2002-03-01 |
2008-05-29 |
The Administrators Of The Tulane Educational Fund |
Conjugates of therapeutic or cytotoxic agents and biologically active peptides
|
|
EP2277543B1
(en)
|
2002-09-06 |
2015-12-16 |
Amgen, Inc |
Therapeutic anti-IL-1R1 monoclonal antibody
|
|
US20040062748A1
(en)
*
|
2002-09-30 |
2004-04-01 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
|
MXPA05006579A
(es)
*
|
2002-12-19 |
2005-12-14 |
Johnson & Johnson |
Metodo para tratar el crecimiento de tejido angiogenico.
|
|
US7432331B2
(en)
|
2002-12-31 |
2008-10-07 |
Nektar Therapeutics Al, Corporation |
Hydrolytically stable maleimide-terminated polymers
|
|
KR101025143B1
(ko)
|
2002-12-31 |
2011-04-01 |
넥타르 테라퓨틱스 |
가수분해상으로 안정한 말레이미드－종결 중합체
|
|
US9028863B2
(en)
|
2003-04-25 |
2015-05-12 |
The Penn State Research Foundation |
Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
|
|
JP2007501811A
(ja)
*
|
2003-08-08 |
2007-02-01 |
ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト |
治療的な関心対象のタンパク質に対する遅延分子の選択的な化学物質接合のためのガラクトースオキシダーゼの使用。
|
|
CA2582242A1
(en)
*
|
2004-10-08 |
2006-04-20 |
Alza Corporation |
Method of insertion of a lipid-linked moiety into a pre-formed lipid assembly using microwaves
|
|
TW200618820A
(en)
*
|
2004-11-05 |
2006-06-16 |
Alza Corp |
Liposome formulations of boronic acid compounds
|
|
TW200726485A
(en)
*
|
2005-07-01 |
2007-07-16 |
Alza Corp |
Liposomal delivery vehicle for hydrophobic drugs
|
|
US20070055199A1
(en)
|
2005-08-10 |
2007-03-08 |
Gilbert Scott J |
Drug delivery device for buccal and aural applications and other areas of the body difficult to access
|
|
WO2007033110A2
(en)
*
|
2005-09-12 |
2007-03-22 |
Alza Corporation |
Liposomes for treatment of multiple myeloma
|
|
PE20070684A1
(es)
|
2005-11-14 |
2007-08-06 |
Amgen Inc |
MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
|
|
US20070264322A1
(en)
*
|
2006-05-10 |
2007-11-15 |
Huang Ken S |
Method for making liposomes conjugated with temperature-sensitive ligands
|
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
|
EP2217258B1
(en)
|
2007-11-14 |
2014-03-26 |
General Regeneratives Limited |
Use of interleukin-1 receptor antagonist as a myeloprotective agent
|
|
HRP20140836T1
(hr)
|
2008-12-22 |
2014-10-10 |
Creabilis S.A. |
Sinteza polimernih konjugata spojeva indolokarbazola
|
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
|
CN101690801B
(zh)
|
2009-10-26 |
2012-08-01 |
上海交通大学 |
白细胞介素-1受体拮抗剂的用途及其药物组合物
|
|
TWI397428B
(zh)
*
|
2009-12-29 |
2013-06-01 |
Ind Tech Res Inst |
標的第四介白素受體之傳輸系統
|
|
DE102010043733A1
(de)
|
2010-11-10 |
2012-05-10 |
Oxprotect Gmbh |
Unbeladene PEGylierte Liposomen zur Verwendung als Arzneimittel zur Prophylaxe und Therapie von hämorrhagischen und thrombo- embolischen Erkrankungen
|
|
US20140234330A1
(en)
|
2011-07-22 |
2014-08-21 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
|
EP2679236A1
(de)
*
|
2012-06-29 |
2014-01-01 |
Zentrum für biomedizinische Technologie der Donau- Universität Krems |
Dosierungsanleitung für endotoxinbindende Lipopeptide
|
|
WO2014050509A1
(ja)
*
|
2012-09-25 |
2014-04-03 |
テルモ株式会社 |
リポソームおよびリポソーム製剤
|
|
JP6542197B2
(ja)
|
2013-04-12 |
2019-07-10 |
エヴォックス・セラピューティクス・リミテッド |
治療的送達小胞
|
|
US20160000936A1
(en)
|
2014-06-10 |
2016-01-07 |
Abbvie Inc. |
Biomarkers for inflammatory disease and methods of using same
|
|
GB201417589D0
(en)
|
2014-10-06 |
2014-11-19 |
Cantab Biopharmaceuticals Patents Ltd |
Pharmaceutical Formulations
|
|
US10041044B2
(en)
|
2016-07-29 |
2018-08-07 |
Trustees Of Boston University |
Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development
|
|
WO2020035482A1
(en)
|
2018-08-13 |
2020-02-20 |
Iltoo Pharma |
Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof
|
|
CN111217993B
(zh)
*
|
2018-11-26 |
2022-05-20 |
沈阳药科大学 |
一种聚乙二醇化酚红及其制备方法和用途
|
|
EP4526469A1
(en)
|
2022-05-16 |
2025-03-26 |
Institut National de la Santé et de la Recherche Médicale |
Methods for assessing the exhaustion of hematopoietic stems cells induced by chronic inflammation
|