JP2005095144A5 - - Google Patents
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- Publication number
- JP2005095144A5 JP2005095144A5 JP2004102903A JP2004102903A JP2005095144A5 JP 2005095144 A5 JP2005095144 A5 JP 2005095144A5 JP 2004102903 A JP2004102903 A JP 2004102903A JP 2004102903 A JP2004102903 A JP 2004102903A JP 2005095144 A5 JP2005095144 A5 JP 2005095144A5
- Authority
- JP
- Japan
- Prior art keywords
- fluorescent marker
- fluorescence lifetime
- group
- biological molecule
- biological
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 17
- 239000003550 marker Substances 0.000 claims 5
- 102000004190 Enzymes Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 238000007876 drug discovery Methods 0.000 claims 2
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 claims 2
- 238000005259 measurement Methods 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 102000003886 Glycoproteins Human genes 0.000 claims 1
- 108090000288 Glycoproteins Proteins 0.000 claims 1
- 102000004895 Lipoproteins Human genes 0.000 claims 1
- 108090001030 Lipoproteins Proteins 0.000 claims 1
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 claims 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 230000002596 correlated effect Effects 0.000 claims 1
- 230000007547 defect Effects 0.000 claims 1
- 230000001678 irradiating effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000026731 phosphorylation Effects 0.000 claims 1
- 238000006366 phosphorylation reaction Methods 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 238000001161 time-correlated single photon counting Methods 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH6532003 | 2003-04-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005095144A JP2005095144A (ja) | 2005-04-14 |
| JP2005095144A5 true JP2005095144A5 (enExample) | 2007-05-24 |
Family
ID=32855168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004102903A Pending JP2005095144A (ja) | 2003-04-10 | 2004-03-31 | 生物学的分子に結合した化学基を測定する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7223610B2 (enExample) |
| EP (1) | EP1467211B1 (enExample) |
| JP (1) | JP2005095144A (enExample) |
| AT (1) | ATE393915T1 (enExample) |
| DE (1) | DE502004006979D1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2542774A1 (en) * | 2003-10-18 | 2005-05-12 | Bayer Healthcare Ag | Direct observation of molecular modifications in biological test systems by measuring fluorescence lifetime |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1994800A (en) * | 1999-01-15 | 2000-08-01 | Pantherix Ltd. | Phosphate release enzyme assay |
| US6410255B1 (en) * | 1999-05-05 | 2002-06-25 | Aurora Biosciences Corporation | Optical probes and assays |
| US6287774B1 (en) * | 1999-05-21 | 2001-09-11 | Caliper Technologies Corp. | Assay methods and system |
| GB0208987D0 (en) * | 2002-04-19 | 2002-05-29 | Amersham Biosciences Uk Ltd | Methods for measuring protein kinase and phosphatase activity |
-
2004
- 2004-03-26 EP EP04007427A patent/EP1467211B1/de not_active Expired - Lifetime
- 2004-03-26 AT AT04007427T patent/ATE393915T1/de not_active IP Right Cessation
- 2004-03-26 DE DE502004006979T patent/DE502004006979D1/de not_active Expired - Lifetime
- 2004-03-31 JP JP2004102903A patent/JP2005095144A/ja active Pending
- 2004-04-08 US US10/820,404 patent/US7223610B2/en not_active Expired - Fee Related
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