JP2005047929A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005047929A5 JP2005047929A5 JP2004273531A JP2004273531A JP2005047929A5 JP 2005047929 A5 JP2005047929 A5 JP 2005047929A5 JP 2004273531 A JP2004273531 A JP 2004273531A JP 2004273531 A JP2004273531 A JP 2004273531A JP 2005047929 A5 JP2005047929 A5 JP 2005047929A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- dextrin
- composition
- body cavity
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001353 Dextrin Polymers 0.000 claims 22
- 239000004375 Dextrin Substances 0.000 claims 22
- 235000019425 dextrin Nutrition 0.000 claims 22
- 239000000203 mixture Substances 0.000 claims 19
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate group Chemical group S(=O)(=O)([O-])[O-] QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 3
- 239000011230 binding agent Substances 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000000314 lubricant Substances 0.000 claims 2
- 210000003200 peritoneal cavity Anatomy 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 238000006116 polymerization reaction Methods 0.000 claims 2
- WCDDVEOXEIYWFB-VXORFPGASA-N (2s,3s,4r,5r,6r)-3-[(2s,3r,5s,6r)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O)[C@H](O)[C@H]1O WCDDVEOXEIYWFB-VXORFPGASA-N 0.000 claims 1
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 102000005701 Calcium-Binding Proteins Human genes 0.000 claims 1
- 108010045403 Calcium-Binding Proteins Proteins 0.000 claims 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- 229920002683 Glycosaminoglycan Polymers 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 239000013011 aqueous formulation Substances 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 claims 1
- 229960001123 epoprostenol Drugs 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 239000003527 fibrinolytic agent Substances 0.000 claims 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 229940014041 hyaluronate Drugs 0.000 claims 1
- 238000002386 leaching Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229960000907 methylthioninium chloride Drugs 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 150000003904 phospholipids Chemical group 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 125000001453 quaternary ammonium group Chemical group 0.000 claims 1
- 230000008929 regeneration Effects 0.000 claims 1
- 238000011069 regeneration method Methods 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9810127.2A GB9810127D0 (en) | 1998-05-13 | 1998-05-13 | Prevention of surgical adhesions |
| US27271399A | 1999-03-19 | 1999-03-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000548018A Division JP3679710B2 (ja) | 1998-05-13 | 1999-05-13 | 外科手術上の癒着を阻止するためのデキストリンを含有する組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005047929A JP2005047929A (ja) | 2005-02-24 |
| JP2005047929A5 true JP2005047929A5 (https=) | 2005-10-06 |
| JP4276601B2 JP4276601B2 (ja) | 2009-06-10 |
Family
ID=26313653
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000548018A Expired - Lifetime JP3679710B2 (ja) | 1998-05-13 | 1999-05-13 | 外科手術上の癒着を阻止するためのデキストリンを含有する組成物 |
| JP2004273531A Expired - Lifetime JP4276601B2 (ja) | 1998-05-13 | 2004-09-21 | 外科手術上の癒着を阻止するためのデキストリンを含有する組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000548018A Expired - Lifetime JP3679710B2 (ja) | 1998-05-13 | 1999-05-13 | 外科手術上の癒着を阻止するためのデキストリンを含有する組成物 |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1085920B1 (https=) |
| JP (2) | JP3679710B2 (https=) |
| CN (1) | CN1181894C (https=) |
| AT (1) | ATE211002T1 (https=) |
| AU (1) | AU740832B2 (https=) |
| BR (1) | BR9911769B8 (https=) |
| CA (1) | CA2331672C (https=) |
| DE (1) | DE69900648T2 (https=) |
| DK (1) | DK1085920T3 (https=) |
| ES (1) | ES2165735T3 (https=) |
| IL (2) | IL139283A0 (https=) |
| NO (1) | NO312709B1 (https=) |
| NZ (2) | NZ507832A (https=) |
| PL (1) | PL194109B1 (https=) |
| PT (1) | PT1085920E (https=) |
| WO (1) | WO1999058168A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001226926A1 (en) * | 2000-01-21 | 2001-07-31 | M.L. Laboratories Plc | Dextrin containing compositions for prevention of adhesions |
| GB2363713A (en) * | 2000-06-21 | 2002-01-09 | Ml Lab Plc | Dextrin compositions |
| GB0115505D0 (en) * | 2001-06-25 | 2001-08-15 | Britannia Pharmaceuticals Ltd | Prevention of surgical adhesions |
| US8252333B2 (en) | 2006-01-26 | 2012-08-28 | Jorge Cueto-Garcia | Biodegradable, non-toxic biological adhesive for use in abdominal surgery |
| JP5059787B2 (ja) | 2007-02-06 | 2012-10-31 | 帝人株式会社 | セルロース誘導体およびその製造方法 |
| DE102008005172A1 (de) * | 2008-01-19 | 2009-07-23 | Mike Ehrlich | Pharmazeutische Zusammensetzung zur Verhinderung von post-operativen Adhäsionen |
| WO2012108753A1 (es) * | 2011-02-08 | 2012-08-16 | Cueto Garcia Jorge | Adhesivo biológico tixotrópico para uso en cavidades internas del cuerpo |
| JP7472142B2 (ja) * | 2019-08-01 | 2024-04-22 | Ｋｍバイオロジクス株式会社 | 生体適合性高分子を用いた組織の線維化抑制剤 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3689863T2 (de) * | 1985-06-22 | 1995-01-05 | Ml Lab Plc | In kontinuierlicher Peritonealdialyse verwendete Polymere. |
| SE457933B (sv) * | 1987-07-06 | 1989-02-13 | Larsson Kare | Farmaceutisk komposition innefattande en vattendispergerad blandning av lipider, monoglycerider och fosfatidylkolin samt dess anvaendning foer framstaellning av en gastronintestinalt verksam kompostion |
| SE8900586L (sv) * | 1989-02-21 | 1990-08-22 | Pharmacia Ab | Komposition och foerfarande foer att foerhindra adhesion mellan kroppsvaevnader |
| DK0426368T3 (da) * | 1989-10-31 | 1995-03-13 | Howmedica | Præparater indeholdende chitinderivater til forebyggelse af adhæsion |
| US5093319A (en) * | 1989-10-31 | 1992-03-03 | Pfizer Hospital Products Group, Inc. | Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions |
| US5318780A (en) * | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
| US5614515A (en) * | 1994-11-17 | 1997-03-25 | University Of Southern California | Lazaroid-based compositions and method for preventing adhesion formation using the same |
| AU698619B2 (en) * | 1995-06-07 | 1998-11-05 | University Of Southern California | Method for reducing or preventing post-surgical adhesion formation using 5-lipoxygenase inhibitors |
| US5807833A (en) * | 1995-06-07 | 1998-09-15 | University Of Southern California | Hydroxyethyl starch and use thereof as an absorbable mechanical barrier and intracavity carrier device |
| JP3925955B2 (ja) * | 1996-04-26 | 2007-06-06 | 株式会社クラレ | 癒着防止材 |
| IN192791B (https=) * | 1996-06-28 | 2004-05-22 | Johnson & Johnson Medical |
-
1999
- 1999-05-13 IL IL13928399A patent/IL139283A0/xx active IP Right Grant
- 1999-05-13 PT PT99920952T patent/PT1085920E/pt unknown
- 1999-05-13 AT AT99920952T patent/ATE211002T1/de active
- 1999-05-13 WO PCT/GB1999/001306 patent/WO1999058168A1/en not_active Ceased
- 1999-05-13 AU AU38336/99A patent/AU740832B2/en not_active Expired
- 1999-05-13 BR BRPI9911769A patent/BR9911769B8/pt not_active IP Right Cessation
- 1999-05-13 EP EP99920952A patent/EP1085920B1/en not_active Expired - Lifetime
- 1999-05-13 CN CNB998060836A patent/CN1181894C/zh not_active Expired - Lifetime
- 1999-05-13 PL PL99344536A patent/PL194109B1/pl unknown
- 1999-05-13 DK DK99920952T patent/DK1085920T3/da active
- 1999-05-13 NZ NZ507832A patent/NZ507832A/xx not_active IP Right Cessation
- 1999-05-13 JP JP2000548018A patent/JP3679710B2/ja not_active Expired - Lifetime
- 1999-05-13 CA CA002331672A patent/CA2331672C/en not_active Expired - Lifetime
- 1999-05-13 NZ NZ523994A patent/NZ523994A/en not_active IP Right Cessation
- 1999-05-13 DE DE69900648T patent/DE69900648T2/de not_active Expired - Lifetime
- 1999-05-13 ES ES99920952T patent/ES2165735T3/es not_active Expired - Lifetime
-
2000
- 2000-10-26 IL IL139283A patent/IL139283A/en not_active IP Right Cessation
- 2000-11-01 NO NO20005492A patent/NO312709B1/no not_active IP Right Cessation
-
2004
- 2004-09-21 JP JP2004273531A patent/JP4276601B2/ja not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Zhang et al. | Preparation and application of chitosan biomaterials in dentistry | |
| Luo et al. | Thermogelling chitosan-based polymers for the treatment of oral mucosa ulcers | |
| US20090227537A1 (en) | Sulfated polysaccharides and uses thereof in medical treatment | |
| CY1112808T1 (el) | Μειγματα ολιγοσακχαριτων προερχομενων απο την ηπαρινη, η παρασκευη τους και φαρμακευτικες συνθεσεις που τα περιεχουν | |
| JP2005047929A5 (https=) | ||
| CA2402421A1 (en) | Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals | |
| JP2012509706A (ja) | 癒着防止用組成物 | |
| JP2005506326A5 (https=) | ||
| CN102973492B (zh) | 一种治疗痔疮的壳聚糖水凝胶及其制备方法 | |
| JP2008515832A5 (https=) | ||
| JP2009519950A5 (https=) | ||
| JPH10218902A5 (https=) | ||
| JP4276601B2 (ja) | 外科手術上の癒着を阻止するためのデキストリンを含有する組成物 | |
| EP3247735B1 (en) | Anionic linear polyglycerol derivatives, a method for manufacturing and applications | |
| CA2392666A1 (en) | Dextrin containing compositions for prevention of adhesions | |
| JP2000038342A (ja) | 褥瘡・損傷皮膚修復用製剤 | |
| JP2012153633A (ja) | 歯科用アルギン酸塩印象材 | |
| CN1557508A (zh) | 一种防粘连膜及其制备方法 | |
| JP2002265369A (ja) | 増殖因子活性増強剤 | |
| CN104706664B (zh) | 一种植物多糖防护冲洗液 | |
| CN115068672A (zh) | 一种具有止血和促进组织修复的生物活性材料及制备方法与应用 | |
| CN121622992A (zh) | 一种用于治疗牙周炎的可注射水凝胶及其制备方法与应用 | |
| Matthew | 10 Chitosan as a Molecular Scaffold for Biomimetic Design of Glycopolymer Biomaterials |