JP2004537275A5 - - Google Patents

Download PDF

Info

Publication number
JP2004537275A5
JP2004537275A5 JP2002566376A JP2002566376A JP2004537275A5 JP 2004537275 A5 JP2004537275 A5 JP 2004537275A5 JP 2002566376 A JP2002566376 A JP 2002566376A JP 2002566376 A JP2002566376 A JP 2002566376A JP 2004537275 A5 JP2004537275 A5 JP 2004537275A5
Authority
JP
Japan
Prior art keywords
dao
polypeptide
schizophrenia
bipolar disorder
depression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002566376A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004537275A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2002/001262 external-priority patent/WO2002066672A2/en
Publication of JP2004537275A publication Critical patent/JP2004537275A/ja
Publication of JP2004537275A5 publication Critical patent/JP2004537275A5/ja
Pending legal-status Critical Current

Links

JP2002566376A 2001-01-16 2002-01-15 D−アミノ酸オキシダーゼおよびd−アスパラギン酸オキシダーゼのアンタゴニストを使用するcns障害の処置 Pending JP2004537275A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26188301P 2001-01-16 2001-01-16
US30544501P 2001-07-13 2001-07-13
US34521101P 2001-10-22 2001-10-22
US33388101P 2001-11-19 2001-11-19
PCT/IB2002/001262 WO2002066672A2 (en) 2001-01-16 2002-01-15 Treatment of cns disorders using d-amino acid oxidase and d-aspartate oxidase antagonists

Publications (2)

Publication Number Publication Date
JP2004537275A JP2004537275A (ja) 2004-12-16
JP2004537275A5 true JP2004537275A5 (https=) 2006-01-05

Family

ID=27500728

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002566376A Pending JP2004537275A (ja) 2001-01-16 2002-01-15 D−アミノ酸オキシダーゼおよびd−アスパラギン酸オキシダーゼのアンタゴニストを使用するcns障害の処置

Country Status (11)

Country Link
EP (1) EP1412515A2 (https=)
JP (1) JP2004537275A (https=)
KR (1) KR20030066813A (https=)
CN (1) CN1568370A (https=)
AU (1) AU2002247939B2 (https=)
BR (1) BR0206495A (https=)
CA (1) CA2433866A1 (https=)
EA (1) EA006654B1 (https=)
IL (1) IL156865A0 (https=)
MX (1) MXPA03006321A (https=)
WO (1) WO2002066672A2 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60228954D1 (en) 2001-05-03 2008-10-30 Galileo Lab Inc Pyruvatderivate
WO2003070743A1 (en) * 2002-02-20 2003-08-28 Ribozyme Pharmaceuticals, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF G72 AND D-AMINO ACID OXIDASE (DAAO) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
EP1291015A1 (en) 2001-09-10 2003-03-12 Lunamed AG Dosage forms having prolonged active ingredient release
WO2003039540A2 (en) * 2001-11-09 2003-05-15 Sepracor Inc. D-amino acid oxidase inhibitors for learning and memory
AU2002339696A1 (en) * 2001-12-03 2003-06-17 Genset S.A. Treatment of cns disorders using d-amino acid oxidase and d-aspartate oxidase inhibitors
US20060234221A1 (en) * 2001-12-12 2006-10-19 Genset S.A. Biallelic markers of d-amino acid oxidase and uses thereof
GB0223424D0 (en) * 2002-10-09 2002-11-13 Imp College Innovations Ltd Disease-associated gene
JP2007517056A (ja) 2003-12-29 2007-06-28 セプラコア インコーポレーテッド ピロール及びピラゾールdaao阻害剤
JP5367377B2 (ja) * 2006-01-09 2013-12-11 オクラホマ メディカル リサーチ ファウンデーション 炎症性疾患治療のためのランチオニン関連化合物
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US7902252B2 (en) * 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
GB2456390A (en) * 2008-01-15 2009-07-22 Glaxo Group Ltd Bipolar disorder treatments
CN102292094B (zh) 2009-01-20 2013-08-14 洛杉矶生物医学研究所在哈伯-加州大学洛杉矶分校医疗中心 增强神经药方疗效的山梨酸与苯甲酸及其衍生物
JP4462382B1 (ja) * 2009-04-23 2010-05-12 学校法人北里研究所 D−アスパラギン酸オキシダーゼおよびd−アミノ酸オキシダーゼに対する新規阻害剤
WO2012135119A1 (en) * 2011-03-25 2012-10-04 Genomind, Llc Biomarker-based detection and treatment of neurodegenerative depression
AU2013203395A1 (en) 2012-03-30 2013-10-17 Isis Pharmaceuticals, Inc. Compositions and methods for modulating TAU expression for reducing seizure and modifying a neurodegenerative syndrome
TWI772856B (zh) 2013-07-19 2022-08-01 美商百健Ma公司 用於調節τ蛋白表現之組合物
ES2936094T3 (es) 2016-06-13 2023-03-14 Syneurx Int Taiwan Corp Cocristales de benzoato de sodio y usos de los mismos
RU2765625C2 (ru) 2016-06-13 2022-02-01 Сайньюрекс Интернэшнл (Тайвань) Корп. Сокристаллы бензоата лития и их применения
US10336679B2 (en) 2016-10-24 2019-07-02 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US11369579B2 (en) 2016-10-24 2022-06-28 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US10098861B1 (en) 2017-10-24 2018-10-16 Syneurx International (Taiwan) Corp. Pharmaceutical composition comprising sodium benzoate compound and clozapine, and uses thereof
CN108504752B (zh) * 2018-06-26 2021-05-11 华中农业大学 一种与母猪繁殖性状关联的分子标记及应用
CN111909907B (zh) * 2020-07-08 2022-05-24 浙江工业大学 天冬氨酸氧化酶突变体、工程菌及其在氧化-还原偶联制备精草铵膦中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668117A (en) * 1991-02-22 1997-09-16 Shapiro; Howard K. Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments
EP1165836A2 (en) * 1999-03-30 2002-01-02 Genset Schizophrenia associated genes, proteins and biallelic markers
WO2001009118A2 (en) * 1999-07-29 2001-02-08 Patrick T Prendergast Dithiolthione compounds for the treatment of neurological disorders and for memory enhancement
WO2001068104A1 (en) * 2000-03-16 2001-09-20 The Mclean Hospital Corporation Compounds for the treatment of psychiatric or substance abuse disorders

Similar Documents

Publication Publication Date Title
JP2004537275A5 (https=)
Smeland et al. Genetic overlap between schizophrenia and volumes of hippocampus, putamen, and intracranial volume indicates shared molecular genetic mechanisms
Sawcer et al. A whole genome screen for linkage disequilibrium in multiple sclerosis confirms disease associations with regions previously linked to susceptibility
Volpi et al. Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia
Stark et al. Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy
Cohen et al. Polymorphisms of the dopamine D4 receptor and response to antipsychotic drugs
Bottomly et al. Evaluating gene expression in C57BL/6J and DBA/2J mouse striatum using RNA-Seq and microarrays
Ciuculete et al. meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes
CA2321226A1 (en) Genomic sequence of the 5-lipoxygenase-activating protein (flap), polymorphic markers thereof and methods for detection of asthma
JP2012503985A5 (https=)
Lutz et al. New genetic approaches to AD: lessons from APOE-TOMM40 phylogenetics
Dey et al. SNP-to-gene linking strategies reveal contributions of enhancer-related and candidate master-regulator genes to autoimmune disease
Betcheva et al. Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene
JP2012507291A5 (https=)
US20080206768A1 (en) Predicting a response to olanzapine
US20050233321A1 (en) Identification of novel polymorphic sites in the human mglur8 gene and uses thereof
WO2008076449A2 (en) Predicting a response to olanzapine
CN103571846B (zh) Atp6v1b2基因突变体及其应用
US20090215043A1 (en) Polymorphic GHSR Nucleic Acids And Uses Thereof
KR102066663B1 (ko) 유전성 말초 신경질환 진단용 마커 및 그의 용도
CN105886609A (zh) 药物不良反应风险评估方法及其装置
CA2469561A1 (en) Methods for determining transcriptional activity
Tore et al. Application of a new method for GWAS in a related case/control sample with known pedigree structure: identification of new loci for nephrolithiasis
JP5376802B2 (ja) タンパク質多型と冠動脈心疾患との関係
US20150315640A1 (en) Identification of the dcps gene on 11q24.2, which encodes the human decapping enzyme scavenger, in non-syndromic autosomal recessive mental retardation, diagnostic probes thereof and methods of identifying subjects with same