JP2004534074A5 - - Google Patents
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- Publication number
- JP2004534074A5 JP2004534074A5 JP2003504977A JP2003504977A JP2004534074A5 JP 2004534074 A5 JP2004534074 A5 JP 2004534074A5 JP 2003504977 A JP2003504977 A JP 2003504977A JP 2003504977 A JP2003504977 A JP 2003504977A JP 2004534074 A5 JP2004534074 A5 JP 2004534074A5
- Authority
- JP
- Japan
- Prior art keywords
- spironolactone
- nanoparticulate
- nanosuspension
- stabilizer
- range
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0114532.5A GB0114532D0 (en) | 2001-06-14 | 2001-06-14 | Novel compositions |
| PCT/IB2002/003136 WO2002102391A2 (en) | 2001-06-14 | 2002-06-14 | Composition comprising nanoparticulate spironolactone |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004534074A JP2004534074A (ja) | 2004-11-11 |
| JP2004534074A5 true JP2004534074A5 (https=) | 2006-01-05 |
| JP4536373B2 JP4536373B2 (ja) | 2010-09-01 |
Family
ID=9916594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003504977A Expired - Fee Related JP4536373B2 (ja) | 2001-06-14 | 2002-06-14 | 新規組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20040151776A1 (https=) |
| EP (1) | EP1429781A2 (https=) |
| JP (1) | JP4536373B2 (https=) |
| AU (1) | AU2002347094A1 (https=) |
| GB (1) | GB0114532D0 (https=) |
| WO (1) | WO2002102391A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0127832D0 (en) * | 2001-11-20 | 2002-01-09 | Jagotec Ag | Method for the preparation of pharmaceutical nanosuspensions |
| CA2480826C (fr) | 2002-04-09 | 2012-02-07 | Flamel Technologies | Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s) |
| ATE411010T1 (de) * | 2002-12-13 | 2008-10-15 | Jagotec Ag | Topische nanopartikel-spironolacton-formulierung |
| JP2006089386A (ja) * | 2004-09-21 | 2006-04-06 | Nippon Tenganyaku Kenkyusho:Kk | ステロイドまたはステロイド誘導体を含有する懸濁性医薬組成物 |
| US9023400B2 (en) * | 2006-05-24 | 2015-05-05 | Flamel Technologies | Prolonged-release multimicroparticulate oral pharmaceutical form |
| US7897691B2 (en) | 2008-05-09 | 2011-03-01 | Gm Global Technology Operations, Inc. | Proton exchange membranes for fuel cell applications |
| JP5185039B2 (ja) * | 2008-09-24 | 2013-04-17 | 富士フイルム株式会社 | 光学フィルム、その製造方法、並びにそれを用いた偏光板及び液晶表示装置 |
| CA3003028A1 (en) * | 2015-10-30 | 2017-05-04 | Cmp Development Llc | Spironolactone aqueous compositions |
| US10493083B2 (en) | 2015-10-30 | 2019-12-03 | Cmp Development Llc | Spironolactone aqueous compositions |
| KR20230142449A (ko) * | 2020-11-17 | 2023-10-11 | 아큐티스 바이오테라퓨틱스, 인크. | 심부 진피 약물 전달을 위한 조성물 및 방법 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4011316A (en) * | 1975-02-24 | 1977-03-08 | Research Institute For Medicine And Chemistry Inc. | Cyclohexa-2,5-diene-1-thiones |
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| DE3623376A1 (de) * | 1986-07-11 | 1988-01-21 | Behringwerke Ag | Pharmazeutische formulierung und verfahren zu deren herstellung |
| US4837211A (en) * | 1987-04-06 | 1989-06-06 | Carolina Medical Products, Inc. | Spironolactone composition |
| US5091188A (en) * | 1990-04-26 | 1992-02-25 | Haynes Duncan H | Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs |
| US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| US5567592A (en) * | 1994-02-02 | 1996-10-22 | Regents Of The University Of California | Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal |
| GB9409778D0 (en) * | 1994-05-16 | 1994-07-06 | Dumex Ltd As | Compositions |
| DE4440337A1 (de) * | 1994-11-11 | 1996-05-15 | Dds Drug Delivery Services Ges | Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit |
| FR2730231B1 (fr) * | 1995-02-02 | 1997-04-04 | Fournier Sca Lab | Association de fenofibrate et de vitamine e, utilisation en therapeutique |
| WO1996024358A1 (en) * | 1995-02-10 | 1996-08-15 | G.D. Searle & Co. | Use of low dose amount of spironolactone for treatment of cardiovascular disease |
| US5510118A (en) * | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| CA2213638C (en) * | 1995-02-24 | 2004-05-04 | Nanosystems L.L.C. | Aerosols containing nanoparticle dispersions |
| US5716928A (en) * | 1995-06-07 | 1998-02-10 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
| US5891469A (en) * | 1997-04-02 | 1999-04-06 | Pharmos Corporation | Solid Coprecipitates for enhanced bioavailability of lipophilic substances |
| US5891845A (en) * | 1997-11-21 | 1999-04-06 | Fuisz Technologies Ltd. | Drug delivery systems utilizing liquid crystal structures |
| UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
| US6180138B1 (en) * | 1999-01-29 | 2001-01-30 | Abbott Laboratories | Process for preparing solid formulations of lipid-regulating agents with enhanced dissolution and absorption |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| ES2240209T3 (es) * | 1999-12-08 | 2005-10-16 | Pharmacia Corporation | Composiciones de eplerenona nanoparticulada. |
| AU2001284772A1 (en) * | 2000-08-10 | 2002-02-25 | Delsys Pharmaceutical Corporation | Improved solid pharmaceutical dosage formulation of hydrophobic drugs |
-
2001
- 2001-06-14 GB GBGB0114532.5A patent/GB0114532D0/en not_active Ceased
-
2002
- 2002-06-14 AU AU2002347094A patent/AU2002347094A1/en not_active Abandoned
- 2002-06-14 JP JP2003504977A patent/JP4536373B2/ja not_active Expired - Fee Related
- 2002-06-14 US US10/480,573 patent/US20040151776A1/en not_active Abandoned
- 2002-06-14 WO PCT/IB2002/003136 patent/WO2002102391A2/en not_active Ceased
- 2002-06-14 EP EP02751549A patent/EP1429781A2/en not_active Withdrawn
-
2007
- 2007-07-25 US US11/881,337 patent/US20080069886A1/en not_active Abandoned
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