WO2009053876A3 - Nir emitters excitable in the visible spectral range and their application in biochemical and medical imaging - Google Patents

Nir emitters excitable in the visible spectral range and their application in biochemical and medical imaging Download PDF

Info

Publication number
WO2009053876A3
WO2009053876A3 PCT/IB2008/054281 IB2008054281W WO2009053876A3 WO 2009053876 A3 WO2009053876 A3 WO 2009053876A3 IB 2008054281 W IB2008054281 W IB 2008054281W WO 2009053876 A3 WO2009053876 A3 WO 2009053876A3
Authority
WO
WIPO (PCT)
Prior art keywords
application
spectral range
visible spectral
excitable
biochemical
Prior art date
Application number
PCT/IB2008/054281
Other languages
French (fr)
Other versions
WO2009053876A2 (en
Inventor
Thomas J Juestel
Helga Hummel
Petra Huppertz
Jacqueline Merikhi
Cornelis R Ronda
Detlef U Wiechert
Original Assignee
Philips Intellectual Property
Koninkl Philips Electronics Nv
Thomas J Juestel
Helga Hummel
Petra Huppertz
Jacqueline Merikhi
Cornelis R Ronda
Detlef U Wiechert
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Intellectual Property, Koninkl Philips Electronics Nv, Thomas J Juestel, Helga Hummel, Petra Huppertz, Jacqueline Merikhi, Cornelis R Ronda, Detlef U Wiechert filed Critical Philips Intellectual Property
Publication of WO2009053876A2 publication Critical patent/WO2009053876A2/en
Publication of WO2009053876A3 publication Critical patent/WO2009053876A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/77Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals
    • C09K11/7783Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals containing two or more rare earth metals one of which being europium
    • C09K11/7795Phosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0063Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0065Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/67Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing refractory metals
    • C09K11/676Aluminates; Silicates
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/67Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing refractory metals
    • C09K11/68Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing refractory metals containing chromium, molybdenum or tungsten
    • C09K11/685Aluminates; Silicates
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/77Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals
    • C09K11/7766Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals containing two or more rare earth metals
    • C09K11/7767Chalcogenides
    • C09K11/7769Oxides
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/77Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals
    • C09K11/7766Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals containing two or more rare earth metals
    • C09K11/7777Phosphates

Abstract

This invention concerns the application of inorganic luminescent nanoscale particles, which exhibit optical transitions in the visible spectral range, which can be exploited for excitation purposes and which show an emission band or lines in the NIR range, preferably between 650 and 1100 nm. These nanoscale particles are eventually coated by SiO 2 or other inert oxides, e.g. Al2O3, in order to decrease toxicity and to enhance particle lifetime in living systems.
PCT/IB2008/054281 2007-10-23 2008-10-17 Nir emitters excitable in the visible spectral range and their application in biochemical and medical imaging WO2009053876A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07119052.4 2007-10-23
EP07119052 2007-10-23

Publications (2)

Publication Number Publication Date
WO2009053876A2 WO2009053876A2 (en) 2009-04-30
WO2009053876A3 true WO2009053876A3 (en) 2009-06-25

Family

ID=40394426

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/054281 WO2009053876A2 (en) 2007-10-23 2008-10-17 Nir emitters excitable in the visible spectral range and their application in biochemical and medical imaging

Country Status (1)

Country Link
WO (1) WO2009053876A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102925975A (en) * 2011-08-09 2013-02-13 上海祥羚光电科技发展有限公司 Making method for YAG single crystal for white light LED
CN102634339B (en) * 2012-03-31 2014-04-02 昆明理工大学 Red long-afterglow fluorescent material of alkaline earth titanate activated by Bi<2+> and preparation method thereof
CN103045250A (en) * 2012-12-14 2013-04-17 华南理工大学 Near-infrared luminescence bio-fluorescence labeling material and preparation method
CN104789223B (en) * 2015-04-28 2016-06-15 安徽师范大学 A kind of fluorescence LaVO of novelty4: the preparation method of Eu nano flower and application thereof
CN106675561B (en) * 2016-12-30 2019-05-21 江苏纳盾科技有限公司 A kind of vanadium molybdate inorganic material, preparation method and application
KR20190058599A (en) * 2017-09-28 2019-05-29 루미리즈 홀딩 비.브이. Wavelength conversion material for light emitting device
CN115322783B (en) * 2022-07-26 2024-03-22 华东师范大学 Gadolinium metaborate fluorescent material co-doped with bismuth ions and/or rare earth ions and synthesis method
CN115746851B (en) * 2022-11-17 2023-09-15 山东大学 Blue light excitable Cr 4+ Doped short-wave infrared luminescent material, preparation method and application
CN115772403B (en) * 2022-12-06 2023-09-29 广州医科大学 Chromium-thulium co-doped blue-violet light-to-narrow spectrum near infrared fluorescent material, and preparation and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0924095A1 (en) * 1997-12-22 1999-06-23 Japan Polychem Corporation Method for laser marking of polyolefin resins
US20020103517A1 (en) * 2000-02-08 2002-08-01 West Jennifer L. Optically-active nanoparticles for use in therapeutic and diagnostic methods
DE102007001903A1 (en) * 2006-11-17 2008-05-21 Merck Patent Gmbh Fluorescent body containing ruby for white or color-on-demand LEDs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0924095A1 (en) * 1997-12-22 1999-06-23 Japan Polychem Corporation Method for laser marking of polyolefin resins
US20020103517A1 (en) * 2000-02-08 2002-08-01 West Jennifer L. Optically-active nanoparticles for use in therapeutic and diagnostic methods
DE102007001903A1 (en) * 2006-11-17 2008-05-21 Merck Patent Gmbh Fluorescent body containing ruby for white or color-on-demand LEDs

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
HAASE M ET AL: "Synthesis and properties of colloidal lanthanide-doped nanocrystals", JOURNAL OF ALLOYS AND COMPOUNDS, ELSEVIER SEQUOIA, LAUSANNE, CH, vol. 303-304, 1 May 2000 (2000-05-01), pages 191 - 197, XP004204357, ISSN: 0925-8388 *
HEBBINK G A ET AL: "LANTHANIDE(III)-DOPED NANOPARTICLES THAT EMIT IN THE NEAR-INFRARED", ADVANCED MATERIALS, WILEY VCH, WEINHEIM, DE, vol. 14, no. 16, 16 August 2002 (2002-08-16), pages 1147 - 1150, XP001130184, ISSN: 0935-9648 *
JUNG ET AL: "Preparation and luminescence properties of LaPO4:Er,Yb nanoparticles", JOURNAL OF LUMINESCENCE, AMSTERDAM, NL, vol. 114, no. 3-4, 1 September 2005 (2005-09-01), pages 307 - 313, XP005001105, ISSN: 0022-2313 *
MEYSSAMY H ET AL: "WET-CHEMICAL SYNTHESIS OF DOPED COLLOIDAL NANOMATERIALS: PARTICLES AND FIBERS OF LAPO4:EU, LAPO4:CE, AND LAPO4:CE,TB", ADVANCED MATERIALS, WILEY VCH, WEINHEIM, DE, vol. 11, no. 10, 9 July 1999 (1999-07-09), pages 840 - 844, XP000865123, ISSN: 0935-9648 *
MOULTON: "Spectroscopic and laser characteristics of Ti:Al2O3", JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B, vol. 3, no. 1, January 1986 (1986-01-01), USA, pages 125 - 133, XP002523322 *
PARK C-S ET AL: "Influence of Eu<3+> doping content on photoluminescence of Gd2O3:Eu<3+> phosphors prepared by liquid-phase reaction method", JOURNAL OF LUMINESCENCE, AMSTERDAM, NL, vol. 118, no. 2, 1 June 2006 (2006-06-01), pages 199 - 204, XP025185830, ISSN: 0022-2313, [retrieved on 20060601] *
RIWOTZKI K ET AL: "LIQUID-PHASE SYNTHESIS OF DOPED NANOPARTICLES: COLLOIDS OF LUMINESCING LAPO4:EU AND CEPO4:TB PARTICLES WITH A NARROW PARTICLE SIZE DISTRIBUTION", JOURNAL OF PHYSICAL CHEMISTRY. B, MATERIALS, SURFACES, INTERFACES AND BIOPHYSICAL, WASHINGTON, DC, US, vol. 104, no. 13, 1 January 2000 (2000-01-01), pages 2824 - 2828, XP001035003, ISSN: 1089-5647 *

Also Published As

Publication number Publication date
WO2009053876A2 (en) 2009-04-30

Similar Documents

Publication Publication Date Title
WO2009053876A3 (en) Nir emitters excitable in the visible spectral range and their application in biochemical and medical imaging
WO2005002542A3 (en) Nanoparticulate meloxican formulations
WO2004108116A3 (en) Stabilized particle dispersions containing surface-modified inorganic nanoparticles
MX2010002343A (en) Photocatalytic coating.
MY157276A (en) Porous barrier media comprising color change indicators
WO2007133290A8 (en) Anti-ox40l antibodies and methods using same
MY160381A (en) Coated phosphor particles with refractive-index adaptation
BRPI0820391A2 (en) Compound, composition and methods of modulating factor 7 expression
WO2006052276A3 (en) Hair coloring and cosmetic compositions comprising carbon nanotubes
EA200701997A1 (en) COMPOSITION OF BISPHOSPHONATE NANOPARTICLES
EP2332904A3 (en) Derivatives of tetracycline compounds
WO2007075901A3 (en) Quinolin- 4 - one derivatives as modulators of abc transporters
MY144114A (en) Painting composition having improved rheological characteristics
WO2010068471A3 (en) Sensitivity oral care compositions
WO2007136893A3 (en) Anti-fgf19 antibodies and methods using same
WO2007130697A8 (en) Anti-ephb4 antibodies and methods using same
DE602006016125D1 (en) DISPERSIBLE AGENTS AND COMPOSITIONS THEREOF
EP2239573A3 (en) Doxorubicin derivatives and conjugates for doxorubicin immunoassay
ATE550405T1 (en) FLUORESCENT MARKING AGENTS AND FLUORESCENT MARKING METHODS
EP1710851A3 (en) Light emitting display
TW200637795A (en) Polyporous material having nanoparticle and their preparation
WO2007002315A3 (en) Nanoparticulate megestrol formulations
IL185997A0 (en) Substituted aryl 1.4-pyrazine derivatives background of the invention
WO2006081337A3 (en) Erastin analogues and their uses for killing cancer cells
WO2005094902A3 (en) Nanoparticles comprising luminescent substances as contrast agent for optical imaging

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08841969

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08841969

Country of ref document: EP

Kind code of ref document: A2