JP2004533890A - 抗不整脈デバイスおよびその使用方法 - Google Patents
抗不整脈デバイスおよびその使用方法 Download PDFInfo
- Publication number
- JP2004533890A JP2004533890A JP2003509964A JP2003509964A JP2004533890A JP 2004533890 A JP2004533890 A JP 2004533890A JP 2003509964 A JP2003509964 A JP 2003509964A JP 2003509964 A JP2003509964 A JP 2003509964A JP 2004533890 A JP2004533890 A JP 2004533890A
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- target site
- delivering
- treatment
- inducing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 99
- 230000003288 anthiarrhythmic effect Effects 0.000 title 1
- 239000003416 antiarrhythmic agent Substances 0.000 title 1
- 206010003119 arrhythmia Diseases 0.000 claims abstract description 44
- 230000006793 arrhythmia Effects 0.000 claims abstract description 44
- 206010016654 Fibrosis Diseases 0.000 claims abstract description 41
- 230000004761 fibrosis Effects 0.000 claims abstract description 41
- 230000001939 inductive effect Effects 0.000 claims abstract description 29
- 206010002329 Aneurysm Diseases 0.000 claims abstract description 19
- 206010061218 Inflammation Diseases 0.000 claims abstract description 14
- 230000004054 inflammatory process Effects 0.000 claims abstract description 14
- 210000002216 heart Anatomy 0.000 claims description 44
- 239000000463 material Substances 0.000 claims description 39
- 230000004044 response Effects 0.000 claims description 35
- 210000003492 pulmonary vein Anatomy 0.000 claims description 29
- 239000000126 substance Substances 0.000 claims description 26
- 230000001746 atrial effect Effects 0.000 claims description 23
- 210000000056 organ Anatomy 0.000 claims description 20
- 239000003814 drug Substances 0.000 claims description 18
- 229940079593 drug Drugs 0.000 claims description 16
- 210000003462 vein Anatomy 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 14
- 102000016942 Elastin Human genes 0.000 claims description 12
- 108010014258 Elastin Proteins 0.000 claims description 12
- 229920002549 elastin Polymers 0.000 claims description 12
- 230000001225 therapeutic effect Effects 0.000 claims description 12
- 102000008186 Collagen Human genes 0.000 claims description 10
- 108010035532 Collagen Proteins 0.000 claims description 10
- 229920001436 collagen Polymers 0.000 claims description 10
- 230000000747 cardiac effect Effects 0.000 claims description 9
- 210000003748 coronary sinus Anatomy 0.000 claims description 9
- 230000015572 biosynthetic process Effects 0.000 claims description 8
- 230000001965 increasing effect Effects 0.000 claims description 8
- 210000000702 aorta abdominal Anatomy 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 6
- 238000000576 coating method Methods 0.000 claims description 6
- 230000004048 modification Effects 0.000 claims description 6
- 238000012986 modification Methods 0.000 claims description 6
- 238000002955 isolation Methods 0.000 claims description 5
- 229910052751 metal Inorganic materials 0.000 claims description 5
- 239000002184 metal Substances 0.000 claims description 5
- 210000001147 pulmonary artery Anatomy 0.000 claims description 5
- 239000000560 biocompatible material Substances 0.000 claims description 4
- 230000004663 cell proliferation Effects 0.000 claims description 4
- 210000005246 left atrium Anatomy 0.000 claims description 4
- 230000008859 change Effects 0.000 claims description 3
- 208000028867 ischemia Diseases 0.000 claims description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 2
- 229910052791 calcium Inorganic materials 0.000 claims description 2
- 239000011575 calcium Substances 0.000 claims description 2
- 230000000149 penetrating effect Effects 0.000 claims description 2
- 238000003786 synthesis reaction Methods 0.000 claims description 2
- 229940126585 therapeutic drug Drugs 0.000 claims description 2
- 230000002685 pulmonary effect Effects 0.000 claims 4
- 208000034693 Laceration Diseases 0.000 claims 2
- 239000012867 bioactive agent Substances 0.000 claims 2
- 230000003187 abdominal effect Effects 0.000 claims 1
- 230000002612 cardiopulmonary effect Effects 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 230000036772 blood pressure Effects 0.000 abstract description 14
- 230000002159 abnormal effect Effects 0.000 abstract description 8
- 206010020772 Hypertension Diseases 0.000 abstract description 7
- 230000000157 blood function Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 description 98
- 206010003658 Atrial Fibrillation Diseases 0.000 description 33
- 210000004204 blood vessel Anatomy 0.000 description 23
- 230000006870 function Effects 0.000 description 20
- 210000004027 cell Anatomy 0.000 description 19
- 210000004369 blood Anatomy 0.000 description 18
- 239000008280 blood Substances 0.000 description 18
- 210000002837 heart atrium Anatomy 0.000 description 17
- 230000003176 fibrotic effect Effects 0.000 description 14
- 238000002679 ablation Methods 0.000 description 11
- 230000000694 effects Effects 0.000 description 11
- 230000007246 mechanism Effects 0.000 description 10
- 230000006378 damage Effects 0.000 description 9
- 210000001367 artery Anatomy 0.000 description 8
- 230000002308 calcification Effects 0.000 description 8
- 210000002808 connective tissue Anatomy 0.000 description 8
- 230000012010 growth Effects 0.000 description 8
- 230000000638 stimulation Effects 0.000 description 8
- 230000008602 contraction Effects 0.000 description 7
- 210000003205 muscle Anatomy 0.000 description 7
- 230000002861 ventricular Effects 0.000 description 7
- 230000005540 biological transmission Effects 0.000 description 6
- 230000006835 compression Effects 0.000 description 6
- 238000007906 compression Methods 0.000 description 6
- 229920000642 polymer Polymers 0.000 description 6
- 239000011148 porous material Substances 0.000 description 6
- 238000002271 resection Methods 0.000 description 6
- 230000002792 vascular Effects 0.000 description 6
- 206010019280 Heart failures Diseases 0.000 description 5
- 210000000709 aorta Anatomy 0.000 description 5
- 230000002763 arrhythmic effect Effects 0.000 description 5
- 210000001992 atrioventricular node Anatomy 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 206010020718 hyperplasia Diseases 0.000 description 5
- 230000028709 inflammatory response Effects 0.000 description 5
- 238000001356 surgical procedure Methods 0.000 description 5
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 230000030833 cell death Effects 0.000 description 4
- 230000001413 cellular effect Effects 0.000 description 4
- 229910052802 copper Inorganic materials 0.000 description 4
- 239000010949 copper Substances 0.000 description 4
- 238000012377 drug delivery Methods 0.000 description 4
- 239000000835 fiber Substances 0.000 description 4
- 210000005003 heart tissue Anatomy 0.000 description 4
- 230000002757 inflammatory effect Effects 0.000 description 4
- 230000003902 lesion Effects 0.000 description 4
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 4
- 229910001000 nickel titanium Inorganic materials 0.000 description 4
- 230000035755 proliferation Effects 0.000 description 4
- 230000033764 rhythmic process Effects 0.000 description 4
- 230000035939 shock Effects 0.000 description 4
- 229910052725 zinc Inorganic materials 0.000 description 4
- 239000011701 zinc Substances 0.000 description 4
- 208000031481 Pathologic Constriction Diseases 0.000 description 3
- 208000003734 Supraventricular Tachycardia Diseases 0.000 description 3
- 206010042600 Supraventricular arrhythmias Diseases 0.000 description 3
- 239000004098 Tetracycline Substances 0.000 description 3
- 208000031737 Tissue Adhesions Diseases 0.000 description 3
- 239000006096 absorbing agent Substances 0.000 description 3
- 210000003484 anatomy Anatomy 0.000 description 3
- 238000004873 anchoring Methods 0.000 description 3
- 239000003146 anticoagulant agent Substances 0.000 description 3
- 230000002490 cerebral effect Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 210000003743 erythrocyte Anatomy 0.000 description 3
- 239000000411 inducer Substances 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 238000013507 mapping Methods 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 230000037361 pathway Effects 0.000 description 3
- -1 polypropylene Polymers 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 231100000241 scar Toxicity 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 230000036262 stenosis Effects 0.000 description 3
- 208000037804 stenosis Diseases 0.000 description 3
- 229930101283 tetracycline Natural products 0.000 description 3
- 229960002180 tetracycline Drugs 0.000 description 3
- 235000019364 tetracycline Nutrition 0.000 description 3
- 150000003522 tetracyclines Chemical class 0.000 description 3
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 description 2
- 102100022875 Hypoxia-inducible factor 1-alpha Human genes 0.000 description 2
- 201000008450 Intracranial aneurysm Diseases 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 description 2
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 description 2
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 description 2
- 206010047281 Ventricular arrhythmia Diseases 0.000 description 2
- 208000002223 abdominal aortic aneurysm Diseases 0.000 description 2
- 229940127219 anticoagulant drug Drugs 0.000 description 2
- 238000010009 beating Methods 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000002876 beta blocker Substances 0.000 description 2
- 229940097320 beta blocking agent Drugs 0.000 description 2
- 208000006218 bradycardia Diseases 0.000 description 2
- 210000005242 cardiac chamber Anatomy 0.000 description 2
- 238000013153 catheter ablation Methods 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 239000002561 chemical irritant Substances 0.000 description 2
- 230000035602 clotting Effects 0.000 description 2
- 239000004020 conductor Substances 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000010339 dilation Effects 0.000 description 2
- 238000002224 dissection Methods 0.000 description 2
- 210000004177 elastic tissue Anatomy 0.000 description 2
- 210000000620 electrically active cell Anatomy 0.000 description 2
- 238000010828 elution Methods 0.000 description 2
- 230000010102 embolization Effects 0.000 description 2
- 210000001174 endocardium Anatomy 0.000 description 2
- 230000003511 endothelial effect Effects 0.000 description 2
- 210000002950 fibroblast Anatomy 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 230000001976 improved effect Effects 0.000 description 2
- 230000006698 induction Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 230000000302 ischemic effect Effects 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 238000002483 medication Methods 0.000 description 2
- 150000002739 metals Chemical class 0.000 description 2
- 238000002428 photodynamic therapy Methods 0.000 description 2
- 239000004633 polyglycolic acid Substances 0.000 description 2
- 230000002980 postoperative effect Effects 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 230000001902 propagating effect Effects 0.000 description 2
- 230000000541 pulsatile effect Effects 0.000 description 2
- LOUPRKONTZGTKE-LHHVKLHASA-N quinidine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@H]2[C@@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-LHHVKLHASA-N 0.000 description 2
- 210000005245 right atrium Anatomy 0.000 description 2
- 230000036573 scar formation Effects 0.000 description 2
- 230000037390 scarring Effects 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 238000011477 surgical intervention Methods 0.000 description 2
- 239000000454 talc Substances 0.000 description 2
- 229910052623 talc Inorganic materials 0.000 description 2
- 230000008719 thickening Effects 0.000 description 2
- 230000000451 tissue damage Effects 0.000 description 2
- 231100000827 tissue damage Toxicity 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 230000001960 triggered effect Effects 0.000 description 2
- 210000005243 upper chamber Anatomy 0.000 description 2
- 206010047302 ventricular tachycardia Diseases 0.000 description 2
- SGTNSNPWRIOYBX-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Chemical compound C1=C(OC)C(OC)=CC=C1CCN(C)CCCC(C#N)(C(C)C)C1=CC=C(OC)C(OC)=C1 SGTNSNPWRIOYBX-UHFFFAOYSA-N 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 229940127291 Calcium channel antagonist Drugs 0.000 description 1
- 208000006017 Cardiac Tamponade Diseases 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- DJBNUMBKLMJRSA-UHFFFAOYSA-N Flecainide Chemical compound FC(F)(F)COC1=CC=C(OCC(F)(F)F)C(C(=O)NCC2NCCCC2)=C1 DJBNUMBKLMJRSA-UHFFFAOYSA-N 0.000 description 1
- 206010018852 Haematoma Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 101001046870 Homo sapiens Hypoxia-inducible factor 1-alpha Proteins 0.000 description 1
- 108050009527 Hypoxia-inducible factor-1 alpha Proteins 0.000 description 1
- ALOBUEHUHMBRLE-UHFFFAOYSA-N Ibutilide Chemical compound CCCCCCCN(CC)CCCC(O)C1=CC=C(NS(C)(=O)=O)C=C1 ALOBUEHUHMBRLE-UHFFFAOYSA-N 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 1
- 208000034827 Neointima Diseases 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 229930012538 Paclitaxel Natural products 0.000 description 1
- 102000015795 Platelet Membrane Glycoproteins Human genes 0.000 description 1
- 108010010336 Platelet Membrane Glycoproteins Proteins 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 208000035965 Postoperative Complications Diseases 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 208000002847 Surgical Wound Diseases 0.000 description 1
- 208000001871 Tachycardia Diseases 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 206010057469 Vascular stenosis Diseases 0.000 description 1
- 208000033774 Ventricular Remodeling Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 1
- 150000001241 acetals Chemical class 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 229940009456 adriamycin Drugs 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 229960005260 amiodarone Drugs 0.000 description 1
- IYIKLHRQXLHMJQ-UHFFFAOYSA-N amiodarone Chemical compound CCCCC=1OC2=CC=CC=C2C=1C(=O)C1=CC(I)=C(OCCN(CC)CC)C(I)=C1 IYIKLHRQXLHMJQ-UHFFFAOYSA-N 0.000 description 1
- 230000002785 anti-thrombosis Effects 0.000 description 1
- 208000007474 aortic aneurysm Diseases 0.000 description 1
- 210000001008 atrial appendage Anatomy 0.000 description 1
- 230000004791 biological behavior Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 230000002051 biphasic effect Effects 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000004375 bundle of his Anatomy 0.000 description 1
- 239000000480 calcium channel blocker Substances 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 230000003399 chemotactic effect Effects 0.000 description 1
- 239000005482 chemotactic factor Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- HSUGRBWQSSZJOP-RTWAWAEBSA-N diltiazem Chemical compound C1=CC(OC)=CC=C1[C@H]1[C@@H](OC(C)=O)C(=O)N(CCN(C)C)C2=CC=CC=C2S1 HSUGRBWQSSZJOP-RTWAWAEBSA-N 0.000 description 1
- 229960004166 diltiazem Drugs 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 229960002994 dofetilide Drugs 0.000 description 1
- IXTMWRCNAAVVAI-UHFFFAOYSA-N dofetilide Chemical compound C=1C=C(NS(C)(=O)=O)C=CC=1CCN(C)CCOC1=CC=C(NS(C)(=O)=O)C=C1 IXTMWRCNAAVVAI-UHFFFAOYSA-N 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000007831 electrophysiology Effects 0.000 description 1
- 238000002001 electrophysiology Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 210000002889 endothelial cell Anatomy 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 229920000295 expanded polytetrafluoroethylene Polymers 0.000 description 1
- 210000002744 extracellular matrix Anatomy 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 210000000630 fibrocyte Anatomy 0.000 description 1
- 230000009795 fibrotic process Effects 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 229960000449 flecainide Drugs 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229960004053 ibutilide Drugs 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 210000004971 interatrial septum Anatomy 0.000 description 1
- 208000021803 junctional tachycardia Diseases 0.000 description 1
- 238000000608 laser ablation Methods 0.000 description 1
- 229960004194 lidocaine Drugs 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000007620 mathematical function Methods 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000028161 membrane depolarization Effects 0.000 description 1
- 229960002237 metoprolol Drugs 0.000 description 1
- IUBSYMUCCVWXPE-UHFFFAOYSA-N metoprolol Chemical compound COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 IUBSYMUCCVWXPE-UHFFFAOYSA-N 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 210000000651 myofibroblast Anatomy 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 229960001592 paclitaxel Drugs 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000004626 polylactic acid Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 229960000244 procainamide Drugs 0.000 description 1
- REQCZEXYDRLIBE-UHFFFAOYSA-N procainamide Chemical compound CCN(CC)CCNC(=O)C1=CC=C(N)C=C1 REQCZEXYDRLIBE-UHFFFAOYSA-N 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 229960000203 propafenone Drugs 0.000 description 1
- JWHAUXFOSRPERK-UHFFFAOYSA-N propafenone Chemical compound CCCNCC(O)COC1=CC=CC=C1C(=O)CCC1=CC=CC=C1 JWHAUXFOSRPERK-UHFFFAOYSA-N 0.000 description 1
- AQHHHDLHHXJYJD-UHFFFAOYSA-N propranolol Chemical compound C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 AQHHHDLHHXJYJD-UHFFFAOYSA-N 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 229960001404 quinidine Drugs 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000029865 regulation of blood pressure Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 210000002796 renal vein Anatomy 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 210000003752 saphenous vein Anatomy 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 230000011218 segmentation Effects 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 210000001013 sinoatrial node Anatomy 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229960002370 sotalol Drugs 0.000 description 1
- ZBMZVLHSJCTVON-UHFFFAOYSA-N sotalol Chemical compound CC(C)NCC(O)C1=CC=C(NS(C)(=O)=O)C=C1 ZBMZVLHSJCTVON-UHFFFAOYSA-N 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 229940032147 starch Drugs 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000019432 tissue death Effects 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 238000009834 vaporization Methods 0.000 description 1
- 230000008016 vaporization Effects 0.000 description 1
- 210000001604 vasa vasorum Anatomy 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
- 210000002620 vena cava superior Anatomy 0.000 description 1
- 210000002073 venous valve Anatomy 0.000 description 1
- 229960001722 verapamil Drugs 0.000 description 1
- PJVWKTKQMONHTI-UHFFFAOYSA-N warfarin Chemical compound OC=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 PJVWKTKQMONHTI-UHFFFAOYSA-N 0.000 description 1
- 229960005080 warfarin Drugs 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
- A61M29/02—Dilators made of swellable material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2478—Passive devices for improving the function of the heart muscle, i.e. devices for reshaping the external surface of the heart, e.g. bags, strips or bands
- A61F2/2481—Devices outside the heart wall, e.g. bags, strips or bands
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2478—Passive devices for improving the function of the heart muscle, i.e. devices for reshaping the external surface of the heart, e.g. bags, strips or bands
- A61F2/2487—Devices within the heart chamber, e.g. splints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/848—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2002/821—Ostial stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/848—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs
- A61F2002/8483—Barbs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
- A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30357301P | 2001-07-06 | 2001-07-06 | |
| PCT/US2002/021774 WO2003003948A1 (en) | 2001-07-06 | 2002-07-08 | Anti-arrhythmia devices and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009032063A Division JP2009142667A (ja) | 2001-07-06 | 2009-02-13 | 抗不整脈デバイスおよびその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004533890A true JP2004533890A (ja) | 2004-11-11 |
| JP2004533890A5 JP2004533890A5 (https=) | 2006-01-05 |
Family
ID=23172707
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003509964A Pending JP2004533890A (ja) | 2001-07-06 | 2002-07-08 | 抗不整脈デバイスおよびその使用方法 |
| JP2009032063A Pending JP2009142667A (ja) | 2001-07-06 | 2009-02-13 | 抗不整脈デバイスおよびその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009032063A Pending JP2009142667A (ja) | 2001-07-06 | 2009-02-13 | 抗不整脈デバイスおよびその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US20030055491A1 (https=) |
| EP (2) | EP1406559A1 (https=) |
| JP (2) | JP2004533890A (https=) |
| AU (1) | AU2002327219B2 (https=) |
| CA (1) | CA2453210A1 (https=) |
| WO (1) | WO2003003948A1 (https=) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005523049A (ja) * | 2002-01-31 | 2005-08-04 | シメッド ライフ システムズ インコーポレイテッド | 生物学的に活性な物質を放出するための医療用デバイス |
| JP2008515566A (ja) * | 2004-10-08 | 2008-05-15 | シンタッハ アクチェンゲゼルシャフト | 心房細動治療のための２段階瘢痕生成 |
| JP2008538512A (ja) * | 2005-02-11 | 2008-10-30 | ボストン サイエンティフィック リミティッド | 電源併用による治療薬デリバリー用体内医療器具 |
| JP2008540007A (ja) * | 2005-05-17 | 2008-11-20 | シンタク アーゲー | 生物分解性組織切断装置、心臓拍動調節系における障害を治療するためのキットおよび方法 |
| JP2014511222A (ja) * | 2011-02-04 | 2014-05-15 | ユニバーシティー オブ マサチューセッツ | 負圧創傷閉鎖器具 |
| KR20200115299A (ko) * | 2019-03-25 | 2020-10-07 | 의료법인 성광의료재단 | 전기전도 차단을 위한 섬유화 유도 약물 용출 스텐트 |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL153753A0 (en) * | 2002-12-30 | 2003-07-06 | Neovasc Medical Ltd | Varying-diameter vascular implant and balloon |
| WO2004043516A2 (en) * | 2002-11-08 | 2004-05-27 | James Robineau Margolis | Device and method for electrical isolation of the pulmonary veins |
| US20040106952A1 (en) * | 2002-12-03 | 2004-06-03 | Lafontaine Daniel M. | Treating arrhythmias by altering properties of tissue |
| WO2004078065A2 (en) | 2003-03-03 | 2004-09-16 | Sinus Rhythm Technologies, Inc. | Electrical conduction block implant device |
| WO2005039689A2 (en) | 2003-10-24 | 2005-05-06 | Sinus Rhythm Technologies, Inc. | Methods and devices for creating cardiac electrical blocks |
| SE526861C2 (sv) * | 2003-11-17 | 2005-11-15 | Syntach Ag | Vävnadslesionsskapande anordning samt en uppsättning av anordningar för behandling av störningar i hjärtrytmregleringssystemet |
| US9398967B2 (en) * | 2004-03-02 | 2016-07-26 | Syntach Ag | Electrical conduction block implant device |
| US20050234540A1 (en) * | 2004-03-12 | 2005-10-20 | Nmt Medical, Inc. | Dilatation systems and methods for left atrial appendage |
| US9039724B2 (en) * | 2004-03-19 | 2015-05-26 | Aga Medical Corporation | Device for occluding vascular defects |
| US8398670B2 (en) | 2004-03-19 | 2013-03-19 | Aga Medical Corporation | Multi-layer braided structures for occluding vascular defects and for occluding fluid flow through portions of the vasculature of the body |
| US8777974B2 (en) * | 2004-03-19 | 2014-07-15 | Aga Medical Corporation | Multi-layer braided structures for occluding vascular defects |
| US8313505B2 (en) * | 2004-03-19 | 2012-11-20 | Aga Medical Corporation | Device for occluding vascular defects |
| US8747453B2 (en) * | 2008-02-18 | 2014-06-10 | Aga Medical Corporation | Stent/stent graft for reinforcement of vascular abnormalities and associated method |
| DE602005009974D1 (de) * | 2004-10-13 | 2008-11-06 | Medtronic Inc | Eichung von biologischen oder pharmazeutischen substanzen |
| US7387604B2 (en) * | 2004-11-03 | 2008-06-17 | Cook Incorporated | Methods for treating valve-associated regions of vascular vessels |
| US20070061010A1 (en) * | 2005-09-09 | 2007-03-15 | Hauser David L | Device and method for reshaping mitral valve annulus |
| WO2007127362A2 (en) * | 2006-04-26 | 2007-11-08 | The Cleveland Clinic Foundation | Apparatus and method for treating cardiovascular diseases |
| US8652201B2 (en) | 2006-04-26 | 2014-02-18 | The Cleveland Clinic Foundation | Apparatus and method for treating cardiovascular diseases |
| CA2647870A1 (en) * | 2006-05-09 | 2007-11-15 | Syntach Ag | Formation of therapeutic scar using small particles |
| EP2018122B1 (en) * | 2006-05-17 | 2011-04-20 | Syntach AG | A controllable device and kit for treatment of disorders in the heart rhythm regulation system |
| US20090209988A1 (en) * | 2006-05-17 | 2009-08-20 | Syntach Ag | Patient configured device, a kit and a method for treatment of disorders in the heart rhythm regulation system |
| WO2008014056A2 (en) * | 2006-06-08 | 2008-01-31 | Daniel Sullivan | Inflammation accelerating prosthesis |
| US20100305603A1 (en) * | 2007-10-17 | 2010-12-02 | Stevan Nielsen | Shape-Changing Medical Device, Kit, Method Of Production, And Method Of Use |
| US7896911B2 (en) | 2007-12-12 | 2011-03-01 | Innovasc Llc | Device and method for tacking plaque to blood vessel wall |
| US9375327B2 (en) | 2007-12-12 | 2016-06-28 | Intact Vascular, Inc. | Endovascular implant |
| US10022250B2 (en) | 2007-12-12 | 2018-07-17 | Intact Vascular, Inc. | Deployment device for placement of multiple intraluminal surgical staples |
| US8128677B2 (en) * | 2007-12-12 | 2012-03-06 | Intact Vascular LLC | Device and method for tacking plaque to a blood vessel wall |
| US10166127B2 (en) | 2007-12-12 | 2019-01-01 | Intact Vascular, Inc. | Endoluminal device and method |
| US9603730B2 (en) | 2007-12-12 | 2017-03-28 | Intact Vascular, Inc. | Endoluminal device and method |
| US7815687B2 (en) * | 2007-12-18 | 2010-10-19 | Med Institute, Inc. | Method of promoting cell proliferation and ingrowth by injury to the native tissue |
| GB0804654D0 (en) | 2008-03-13 | 2008-04-16 | Smith & Nephew | Vacuum closure device |
| US8844525B2 (en) * | 2008-07-25 | 2014-09-30 | Resmed Limited | Method and apparatus for detecting and treating heart failure |
| US9138233B2 (en) * | 2011-03-17 | 2015-09-22 | Micokoll Inc. | Apparatus and method for tissue adhesion |
| WO2010033725A2 (en) * | 2008-09-20 | 2010-03-25 | Steven Craig Anderson | Apparatus and method for tissue adhesion |
| WO2012016886A2 (de) * | 2010-07-26 | 2012-02-09 | Hans Reiner Figulla | Medizinisches implantat zur endovaskulären stabilisierung von gefässwänden und verfahren zum herstellen eines deartigen implantats |
| CN105617474B (zh) | 2010-11-16 | 2021-02-02 | Tva医疗公司 | 用于形成瘘管的装置和方法 |
| US9421132B2 (en) | 2011-02-04 | 2016-08-23 | University Of Massachusetts | Negative pressure wound closure device |
| WO2012149167A2 (en) | 2011-04-26 | 2012-11-01 | Christopher Gerard Kunis | Method and device for treatment of hypertension and other maladies |
| US10285831B2 (en) | 2011-06-03 | 2019-05-14 | Intact Vascular, Inc. | Endovascular implant |
| EP2806826B1 (en) | 2012-01-25 | 2020-01-08 | Intact Vascular, Inc. | Endoluminal device |
| WO2013121725A1 (ja) * | 2012-02-14 | 2013-08-22 | テルモ株式会社 | 治療デバイス及び治療セット |
| US8934988B2 (en) * | 2012-03-16 | 2015-01-13 | St. Jude Medical Ab | Ablation stent with meander structure |
| MX2014014265A (es) | 2012-05-22 | 2015-06-23 | Smith & Nephew | Dispositivo para cierre de heridas. |
| JP6382185B2 (ja) | 2012-05-22 | 2018-08-29 | スミス アンド ネフュー ピーエルシーＳｍｉｔｈ ＆ Ｎｅｐｈｅｗ Ｐｕｂｌｉｃ Ｌｉｍｉｔｅｄ Ｃｏｍｐａｎｙ | 創傷治療のための装置および方法 |
| US10117782B2 (en) | 2012-05-24 | 2018-11-06 | Smith & Nephew, Inc. | Devices and methods for treating and closing wounds with negative pressure |
| CN110448407B (zh) | 2012-07-16 | 2022-08-09 | 史密夫和内修有限公司 | 负压伤口闭合设备 |
| CA2887557C (en) | 2012-10-11 | 2022-05-17 | Tva Medical, Inc. | Devices and methods for fistula formation |
| WO2014165275A1 (en) | 2013-03-13 | 2014-10-09 | Smith & Nephew Inc. | Negative pressure wound closure device and systems and methods of use in treating wounds with negative pressure |
| AU2014236149A1 (en) | 2013-03-14 | 2015-09-17 | Tva Medical, Inc. | Fistula formation devices and methods therefor |
| EP2968015B1 (en) | 2013-03-14 | 2018-05-16 | Smith & Nephew PLC | Compressible wound fillers and systems and methods of use in treating wounds with negative pressure |
| AU2014291873B2 (en) | 2013-07-16 | 2019-01-24 | Smith & Nephew Plc | Apparatus for wound therapy |
| CA2926470C (en) | 2013-10-21 | 2023-03-14 | Smith & Nephew, Inc. | Negative pressure wound closure device |
| RU2016133734A (ru) | 2014-01-21 | 2018-03-02 | СМИТ ЭНД НЕФЬЮ ПиЭлСи | Устройства для лечения ран |
| RU2016133735A (ru) | 2014-01-21 | 2018-02-28 | СМИТ ЭНД НЕФЬЮ ПиЭлСи | Сжимаемая повязка для лечения раны отрицательным давлением |
| US10695534B2 (en) | 2014-03-14 | 2020-06-30 | Tva Medical, Inc. | Fistula formation devices and methods therefor |
| WO2016033374A1 (en) | 2014-08-27 | 2016-03-03 | Tva Medical, Inc. | Cryolipopysis devices and methods therefor |
| US9433520B2 (en) | 2015-01-29 | 2016-09-06 | Intact Vascular, Inc. | Delivery device and method of delivery |
| US9375336B1 (en) | 2015-01-29 | 2016-06-28 | Intact Vascular, Inc. | Delivery device and method of delivery |
| US10603040B1 (en) | 2015-02-09 | 2020-03-31 | Tva Medical, Inc. | Methods for treating hypertension and reducing blood pressure with formation of fistula |
| WO2016145391A1 (en) * | 2015-03-11 | 2016-09-15 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Expansible cardiovascular graft system |
| AU2016254119A1 (en) | 2015-04-29 | 2017-10-05 | Smith & Nephew Inc. | Negative pressure wound closure device |
| CN108366866A (zh) | 2015-10-12 | 2018-08-03 | 瑞弗罗医疗公司 | 具有突出的药物递送特征部的支架以及相关的系统和方法 |
| US11471586B2 (en) | 2015-12-15 | 2022-10-18 | University Of Massachusetts | Negative pressure wound closure devices and methods |
| US10575991B2 (en) | 2015-12-15 | 2020-03-03 | University Of Massachusetts | Negative pressure wound closure devices and methods |
| US10814049B2 (en) | 2015-12-15 | 2020-10-27 | University Of Massachusetts | Negative pressure wound closure devices and methods |
| US10993824B2 (en) | 2016-01-01 | 2021-05-04 | Intact Vascular, Inc. | Delivery device and method of delivery |
| EP3402432B1 (en) | 2016-01-15 | 2023-05-31 | TVA Medical, Inc. | Devices for forming a fistula |
| WO2017124060A1 (en) | 2016-01-15 | 2017-07-20 | Tva Medical, Inc. | Systems and methods for adhering vessels |
| US10874422B2 (en) | 2016-01-15 | 2020-12-29 | Tva Medical, Inc. | Systems and methods for increasing blood flow |
| EP3402561B1 (en) | 2016-01-15 | 2024-02-28 | TVA Medical, Inc. | Devices for advancing a wire |
| US11135351B2 (en) | 2016-08-30 | 2021-10-05 | Smith & Nephew Plc | Systems and methods for applying reduced pressure therapy |
| AU2017331090C1 (en) | 2016-09-25 | 2023-08-03 | Tva Medical, Inc. | Vascular stent devices and methods |
| EP3518847B1 (en) | 2016-09-27 | 2023-03-01 | Smith & Nephew plc | Wound closure devices with dissolvable portions |
| CA3042673A1 (en) | 2016-11-02 | 2018-05-11 | Smith & Nephew Inc. | Wound closure devices |
| WO2018229010A1 (en) | 2017-06-13 | 2018-12-20 | Smith & Nephew Plc | Collapsible structure and method of use |
| JP7179022B2 (ja) | 2017-06-13 | 2022-11-28 | スミス アンド ネフュー ピーエルシー | 創傷閉鎖装置および使用方法 |
| US11724020B2 (en) | 2017-06-14 | 2023-08-15 | Smith & Nephew Plc | Collapsible sheet for wound closure and method of use |
| US11395873B2 (en) | 2017-06-14 | 2022-07-26 | Smith & Nephew, Inc. | Control of wound closure and fluid removal management in wound therapy |
| CN110678212B (zh) | 2017-06-14 | 2023-01-03 | 史密夫和内修有限公司 | 伤口治疗中的流体去除管理和伤口闭合的控制 |
| US11583623B2 (en) | 2017-06-14 | 2023-02-21 | Smith & Nephew Plc | Collapsible structure for wound closure and method of use |
| US11660218B2 (en) | 2017-07-26 | 2023-05-30 | Intact Vascular, Inc. | Delivery device and method of delivery |
| WO2019020544A1 (en) | 2017-07-27 | 2019-01-31 | Smith & Nephew Plc | CUSTOM WELD CLOSURE DEVICE AND METHOD OF USE |
| WO2019030136A1 (en) | 2017-08-07 | 2019-02-14 | Smith & Nephew Plc | WELD CLOSURE DEVICE WITH PROTECTIVE LAYER AND METHOD OF USE |
| EP3675925B1 (en) | 2017-08-29 | 2025-12-03 | Smith & Nephew PLC | Systems for monitoring wound closure |
| CN110101486B (zh) | 2018-02-01 | 2024-02-27 | 上海微创心通医疗科技有限公司 | 心脏瓣膜假体及其输送器 |
| EP4663171A3 (en) | 2018-06-05 | 2026-02-25 | Boston Scientific Scimed, Inc. | Stent with selectively curved region |
| WO2020096862A1 (en) * | 2018-11-08 | 2020-05-14 | Edwards Lifesciences Corporation | Percutaneous treatment of heart failure with reduced ejection fraction |
| WO2025188999A1 (en) * | 2024-03-07 | 2025-09-12 | Edwards Lifesciences Corporation | Addressing elevated left-sided filling pressures |
Family Cites Families (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5104399A (en) * | 1986-12-10 | 1992-04-14 | Endovascular Technologies, Inc. | Artificial graft and implantation method |
| US4580568A (en) * | 1984-10-01 | 1986-04-08 | Cook, Incorporated | Percutaneous endovascular stent and method for insertion thereof |
| US5176135A (en) * | 1989-09-06 | 1993-01-05 | Ventritex, Inc. | Implantable defibrillation electrode system |
| US5545208A (en) * | 1990-02-28 | 1996-08-13 | Medtronic, Inc. | Intralumenal drug eluting prosthesis |
| US5622698A (en) * | 1990-06-08 | 1997-04-22 | Miami University | Method and composition for increasing the supercooling point in invertebrates |
| US5312456A (en) * | 1991-01-31 | 1994-05-17 | Carnegie Mellon University | Micromechanical barb and method for making the same |
| US5649906A (en) * | 1991-07-17 | 1997-07-22 | Gory; Pierre | Method for implanting a removable medical apparatus in a human body |
| US5500013A (en) * | 1991-10-04 | 1996-03-19 | Scimed Life Systems, Inc. | Biodegradable drug delivery vascular stent |
| US5234448A (en) * | 1992-02-28 | 1993-08-10 | Shadyside Hospital | Method and apparatus for connecting and closing severed blood vessels |
| US5360440A (en) * | 1992-03-09 | 1994-11-01 | Boston Scientific Corporation | In situ apparatus for generating an electrical current in a biological environment |
| DE669839T1 (de) | 1992-10-01 | 1996-10-10 | Cardiac Pacemakers | Stentartige struktur für entflimmerungselektroden. |
| SE9203732D0 (sv) | 1992-12-11 | 1992-12-11 | Siemens Elema Ab | Elektrodsystem foer defibrillator |
| US6010531A (en) * | 1993-02-22 | 2000-01-04 | Heartport, Inc. | Less-invasive devices and methods for cardiac valve surgery |
| US5464650A (en) * | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
| US5551426A (en) * | 1993-07-14 | 1996-09-03 | Hummel; John D. | Intracardiac ablation and mapping catheter |
| US5735892A (en) * | 1993-08-18 | 1998-04-07 | W. L. Gore & Associates, Inc. | Intraluminal stent graft |
| WO1995016407A1 (en) * | 1993-12-13 | 1995-06-22 | Brigham And Women's Hospital | Aortic valve supporting device |
| US5507775A (en) * | 1994-01-21 | 1996-04-16 | Progressive Surgical Products Inc. | Tissue expansion and approximation device |
| US5423851A (en) * | 1994-03-06 | 1995-06-13 | Samuels; Shaun L. W. | Method and apparatus for affixing an endoluminal device to the walls of tubular structures within the body |
| US5509924A (en) * | 1994-04-12 | 1996-04-23 | Ventritex, Inc. | Epicardial stimulation electrode with energy directing capability |
| US5507779A (en) * | 1994-04-12 | 1996-04-16 | Ventritex, Inc. | Cardiac insulation for defibrillation |
| US5397355A (en) * | 1994-07-19 | 1995-03-14 | Stentco, Inc. | Intraluminal stent |
| US5891108A (en) * | 1994-09-12 | 1999-04-06 | Cordis Corporation | Drug delivery stent |
| US5545183A (en) * | 1994-12-07 | 1996-08-13 | Ventritex, Inc. | Method and apparatus for delivering defibrillation therapy through a sensing electrode |
| US5551427A (en) * | 1995-02-13 | 1996-09-03 | Altman; Peter A. | Implantable device for the effective elimination of cardiac arrhythmogenic sites |
| US6579314B1 (en) * | 1995-03-10 | 2003-06-17 | C.R. Bard, Inc. | Covered stent with encapsulated ends |
| US5674272A (en) * | 1995-06-05 | 1997-10-07 | Ventritex, Inc. | Crush resistant implantable lead |
| US5713863A (en) * | 1996-01-11 | 1998-02-03 | Interventional Technologies Inc. | Catheter with fluid medication injectors |
| ATE218052T1 (de) * | 1995-11-27 | 2002-06-15 | Schneider Europ Gmbh | Stent zur anwendung in einem körperlichen durchgang |
| US5662698A (en) | 1995-12-06 | 1997-09-02 | Ventritex, Inc. | Nonshunting endocardial defibrillation lead |
| US5658327A (en) * | 1995-12-19 | 1997-08-19 | Ventritex, Inc. | Intracardiac lead having a compliant fixation device |
| US5824030A (en) * | 1995-12-21 | 1998-10-20 | Pacesetter, Inc. | Lead with inter-electrode spacing adjustment |
| US5617878A (en) * | 1996-05-31 | 1997-04-08 | Taheri; Syde A. | Stent and method for treatment of aortic occlusive disease |
| JP2002515785A (ja) * | 1996-06-25 | 2002-05-28 | メドトロニック，インコーポレイテッド | 一定の特性を有する管腔内補綴具の集団およびその製造方法 |
| JPH1015250A (ja) * | 1996-06-28 | 1998-01-20 | Sega Enterp Ltd | ゲーム装置 |
| EP0941116B1 (en) * | 1996-11-01 | 2005-01-19 | Ark Therapeutics Limited | Use of vegf for the manufacture of a medicament for the treatment or prevention of intimal hyperplasia and delivery device |
| US5833651A (en) * | 1996-11-08 | 1998-11-10 | Medtronic, Inc. | Therapeutic intraluminal stents |
| US5749890A (en) * | 1996-12-03 | 1998-05-12 | Shaknovich; Alexander | Method and system for stent placement in ostial lesions |
| US5871437A (en) * | 1996-12-10 | 1999-02-16 | Inflow Dynamics, Inc. | Radioactive stent for treating blood vessels to prevent restenosis |
| US6039757A (en) * | 1997-03-12 | 2000-03-21 | Cardiosynopsis, Inc. | In situ formed fenestrated stent |
| US6443949B2 (en) * | 1997-03-13 | 2002-09-03 | Biocardia, Inc. | Method of drug delivery to interstitial regions of the myocardium |
| US6086582A (en) * | 1997-03-13 | 2000-07-11 | Altman; Peter A. | Cardiac drug delivery system |
| US6425915B1 (en) * | 1997-03-18 | 2002-07-30 | Endotex Interventional Systems, Inc. | Helical mesh endoprosthesis and methods of use |
| US5954761A (en) * | 1997-03-25 | 1999-09-21 | Intermedics Inc. | Implantable endocardial lead assembly having a stent |
| US6096071A (en) * | 1998-03-26 | 2000-08-01 | Yadav; Jay S. | Ostial stent |
| US5843169A (en) * | 1997-04-08 | 1998-12-01 | Taheri; Syde A. | Apparatus and method for stapling graft material to a blood vessel wall while preserving the patency of orifices |
| US6012457A (en) * | 1997-07-08 | 2000-01-11 | The Regents Of The University Of California | Device and method for forming a circumferential conduction block in a pulmonary vein |
| US5938660A (en) * | 1997-06-27 | 1999-08-17 | Daig Corporation | Process and device for the treatment of atrial arrhythmia |
| US6164283A (en) * | 1997-07-08 | 2000-12-26 | The Regents Of The University Of California | Device and method for forming a circumferential conduction block in a pulmonary vein |
| US5910144A (en) * | 1998-01-09 | 1999-06-08 | Endovascular Technologies, Inc. | Prosthesis gripping system and method |
| US6224626B1 (en) * | 1998-02-17 | 2001-05-01 | Md3, Inc. | Ultra-thin expandable stent |
| US6296630B1 (en) * | 1998-04-08 | 2001-10-02 | Biocardia, Inc. | Device and method to slow or stop the heart temporarily |
| US20010044619A1 (en) * | 1998-04-08 | 2001-11-22 | Peter A. Altman | Cardiac drug delivery system and method for use |
| NL1009028C2 (nl) | 1998-04-28 | 1999-10-29 | Adri Marinus Blomme | Hechtmiddelen voor het verbinden van een buisvormige vaatprothese met een bloedvat in het lichaam alsmede aftakkingsmiddelen, een vaatprothese, een inrichting voor het in het lichaam inbrengen en aanhechten van een vaatprothese en een vaatprothesesysteem. |
| US6206914B1 (en) * | 1998-04-30 | 2001-03-27 | Medtronic, Inc. | Implantable system with drug-eluting cells for on-demand local drug delivery |
| US6179858B1 (en) * | 1998-05-12 | 2001-01-30 | Massachusetts Institute Of Technology | Stent expansion and apposition sensing |
| US6296603B1 (en) * | 1998-05-26 | 2001-10-02 | Isostent, Inc. | Radioactive intraluminal endovascular prosthesis and method for the treatment of aneurysms |
| US6153252A (en) * | 1998-06-30 | 2000-11-28 | Ethicon, Inc. | Process for coating stents |
| US6102887A (en) * | 1998-08-11 | 2000-08-15 | Biocardia, Inc. | Catheter drug delivery system and method for use |
| US6363938B2 (en) * | 1998-12-22 | 2002-04-02 | Angiotrax, Inc. | Methods and apparatus for perfusing tissue and/or stimulating revascularization and tissue growth |
| CA2355873A1 (en) * | 1998-12-31 | 2000-07-13 | Angiotech Pharmaceuticals, Inc. | Stent grafts with bioactive coatings |
| US6210392B1 (en) * | 1999-01-15 | 2001-04-03 | Interventional Technologies, Inc. | Method for treating a wall of a blood vessel |
| IT1307765B1 (it) * | 1999-02-05 | 2001-11-19 | Pietro Quaretti | Endoprotesi tubolare, in particolare per l'uso nei dotti ureterali ebiliari, nonche' nell'esofago. |
| US6161029A (en) * | 1999-03-08 | 2000-12-12 | Medtronic, Inc. | Apparatus and method for fixing electrodes in a blood vessel |
| DE19912635A1 (de) * | 1999-03-20 | 2000-09-21 | Biotronik Mess & Therapieg | Dilatierbare Herzelektrodenanordnung zur Implantation insbesondere im Koronarsinus des Herzens |
| US6267776B1 (en) * | 1999-05-03 | 2001-07-31 | O'connell Paul T. | Vena cava filter and method for treating pulmonary embolism |
| US6245101B1 (en) * | 1999-05-03 | 2001-06-12 | William J. Drasler | Intravascular hinge stent |
| WO2001019269A1 (en) | 1999-09-15 | 2001-03-22 | The General Hospital Corporation D.B.A Massachusetts General Hospital | Pulmonary vein ablation stent and method |
| AU8023200A (en) * | 1999-10-13 | 2001-04-23 | Biocardia, Inc. | Pulmonary vein stent and method for use |
| US20020026228A1 (en) * | 1999-11-30 | 2002-02-28 | Patrick Schauerte | Electrode for intravascular stimulation, cardioversion and/or defibrillation |
| US6517573B1 (en) * | 2000-04-11 | 2003-02-11 | Endovascular Technologies, Inc. | Hook for attaching to a corporeal lumen and method of manufacturing |
| US6821295B1 (en) | 2000-06-26 | 2004-11-23 | Thoratec Corporation | Flared coronary artery bypass grafts |
| US6572652B2 (en) * | 2000-08-29 | 2003-06-03 | Venpro Corporation | Method and devices for decreasing elevated pulmonary venous pressure |
| CA2423360A1 (en) | 2000-09-21 | 2002-03-28 | Atritech, Inc. | Apparatus for implanting devices in atrial appendages |
| US6254632B1 (en) * | 2000-09-28 | 2001-07-03 | Advanced Cardiovascular Systems, Inc. | Implantable medical device having protruding surface structures for drug delivery and cover attachment |
| US20020077691A1 (en) * | 2000-12-18 | 2002-06-20 | Advanced Cardiovascular Systems, Inc. | Ostial stent and method for deploying same |
| JP2004524909A (ja) | 2001-03-09 | 2004-08-19 | ジョージア テック リサーチ コーポレイション | 血管の軸方向への伸張のための脈管内デバイスおよび方法 |
| US6500186B2 (en) * | 2001-04-17 | 2002-12-31 | Scimed Life Systems, Inc. | In-stent ablative tool |
| US7493162B2 (en) * | 2001-06-15 | 2009-02-17 | Cardiac Pacemakers, Inc. | Pulmonary vein stent for treating atrial fibrillation |
-
2002
- 2002-07-08 WO PCT/US2002/021774 patent/WO2003003948A1/en not_active Ceased
- 2002-07-08 EP EP02763249A patent/EP1406559A1/en not_active Ceased
- 2002-07-08 CA CA002453210A patent/CA2453210A1/en not_active Abandoned
- 2002-07-08 AU AU2002327219A patent/AU2002327219B2/en not_active Ceased
- 2002-07-08 EP EP12185964.9A patent/EP2572674A3/en not_active Withdrawn
- 2002-07-08 US US10/192,402 patent/US20030055491A1/en not_active Abandoned
- 2002-07-08 JP JP2003509964A patent/JP2004533890A/ja active Pending
-
2006
- 2006-10-20 US US11/551,670 patent/US8579955B2/en not_active Expired - Fee Related
-
2009
- 2009-02-13 JP JP2009032063A patent/JP2009142667A/ja active Pending
-
2013
- 2013-10-28 US US14/065,220 patent/US20140052169A1/en not_active Abandoned
-
2015
- 2015-12-04 US US14/960,266 patent/US20160082234A1/en not_active Abandoned
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005523049A (ja) * | 2002-01-31 | 2005-08-04 | シメッド ライフ システムズ インコーポレイテッド | 生物学的に活性な物質を放出するための医療用デバイス |
| JP2008515566A (ja) * | 2004-10-08 | 2008-05-15 | シンタッハ アクチェンゲゼルシャフト | 心房細動治療のための２段階瘢痕生成 |
| JP2008538512A (ja) * | 2005-02-11 | 2008-10-30 | ボストン サイエンティフィック リミティッド | 電源併用による治療薬デリバリー用体内医療器具 |
| JP2008540007A (ja) * | 2005-05-17 | 2008-11-20 | シンタク アーゲー | 生物分解性組織切断装置、心臓拍動調節系における障害を治療するためのキットおよび方法 |
| JP2008540006A (ja) * | 2005-05-17 | 2008-11-20 | シンタク アーゲー | 心臓拍動調節系における障害の治療のための双安定性装置、キットおよび方法 |
| JP2014511222A (ja) * | 2011-02-04 | 2014-05-15 | ユニバーシティー オブ マサチューセッツ | 負圧創傷閉鎖器具 |
| KR20200115299A (ko) * | 2019-03-25 | 2020-10-07 | 의료법인 성광의료재단 | 전기전도 차단을 위한 섬유화 유도 약물 용출 스텐트 |
| KR102432918B1 (ko) * | 2019-03-25 | 2022-08-17 | 연세대학교 산학협력단 | 전기전도 차단을 위한 섬유화 유도 약물 용출 스텐트 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009142667A (ja) | 2009-07-02 |
| US20070049866A1 (en) | 2007-03-01 |
| CA2453210A1 (en) | 2003-01-16 |
| US8579955B2 (en) | 2013-11-12 |
| US20160082234A1 (en) | 2016-03-24 |
| WO2003003948A1 (en) | 2003-01-16 |
| EP2572674A2 (en) | 2013-03-27 |
| EP1406559A1 (en) | 2004-04-14 |
| AU2002327219B2 (en) | 2009-04-23 |
| EP2572674A3 (en) | 2013-08-07 |
| US20140052169A1 (en) | 2014-02-20 |
| US20030055491A1 (en) | 2003-03-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2002327219B2 (en) | Anti-arrhythmia devices and methods of use | |
| AU2002327219A1 (en) | Anti-arrhythmia devices and methods of use | |
| EP1143879B1 (en) | Imbedded intramuscular implants | |
| US20260108742A1 (en) | Devices and methods for treating cardiovascular and metabolic disease | |
| RU2372052C2 (ru) | Устройство, комплект и способ для лечения нарушений в системе регуляции ритма сердца | |
| US7209783B2 (en) | Ablation stent for treating atrial fibrillation | |
| US8696696B2 (en) | Device and kit for treatment of disorders in the heart rhythm regulation system | |
| US20150151077A1 (en) | Devices And Methods For Renal Denervation | |
| EP1708642A1 (en) | Ventricular partitioning device | |
| US20180154123A1 (en) | Implants and systems for electrically isolating one or more pulminary veins | |
| WO2013016349A2 (en) | Vessel treatment methods and devices for use in a graft device | |
| RU2394522C2 (ru) | Способ достижения трансмуральности повреждения миокарда предсердий при лечении наджелудочковых аритмий и устройство для его осуществления | |
| US6342051B1 (en) | Treatment of anoxic tissue with angiogenesis-inducing implants | |
| HK1111587B (en) | A device and kit for treatment of disorders in the heart rhythm regulation system | |
| HK1111881A (en) | A bistable device, a kit and a method for treatment of disorders in the heart rhythm regulation system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050706 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20050706 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20080815 |
|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20080916 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20080916 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20081105 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20081112 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20081212 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20081219 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20090114 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20090121 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090213 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090312 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20090609 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20090616 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20090708 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20090715 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20090731 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20090807 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20091127 |