JP2004533250A5 - - Google Patents

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Publication number
JP2004533250A5
JP2004533250A5 JP2002592975A JP2002592975A JP2004533250A5 JP 2004533250 A5 JP2004533250 A5 JP 2004533250A5 JP 2002592975 A JP2002592975 A JP 2002592975A JP 2002592975 A JP2002592975 A JP 2002592975A JP 2004533250 A5 JP2004533250 A5 JP 2004533250A5
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JP
Japan
Prior art keywords
cell
cells
domain
medicament
manufacture
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002592975A
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English (en)
Japanese (ja)
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JP2004533250A (ja
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Publication date
Priority claimed from GBGB0112687.9A external-priority patent/GB0112687D0/en
Application filed filed Critical
Publication of JP2004533250A publication Critical patent/JP2004533250A/ja
Publication of JP2004533250A5 publication Critical patent/JP2004533250A5/ja
Pending legal-status Critical Current

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JP2002592975A 2001-05-24 2002-05-21 分泌された細菌エフェクタータンパク質の薬学的使用 Pending JP2004533250A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0112687.9A GB0112687D0 (en) 2001-05-24 2001-05-24 Pharmaceutical use of secreted bacterial effector proteins
PCT/GB2002/002384 WO2002096467A2 (en) 2001-05-24 2002-05-21 Pharmaceutical use for secreted bacterial effector proteins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009202601A Division JP2009286794A (ja) 2001-05-24 2009-09-02 分泌された細菌エフェクタータンパク質の薬学的使用

Publications (2)

Publication Number Publication Date
JP2004533250A JP2004533250A (ja) 2004-11-04
JP2004533250A5 true JP2004533250A5 (https=) 2005-12-22

Family

ID=9915236

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002592975A Pending JP2004533250A (ja) 2001-05-24 2002-05-21 分泌された細菌エフェクタータンパク質の薬学的使用
JP2009202601A Pending JP2009286794A (ja) 2001-05-24 2009-09-02 分泌された細菌エフェクタータンパク質の薬学的使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009202601A Pending JP2009286794A (ja) 2001-05-24 2009-09-02 分泌された細菌エフェクタータンパク質の薬学的使用

Country Status (8)

Country Link
US (1) US20040208889A1 (https=)
EP (1) EP1390400A2 (https=)
JP (2) JP2004533250A (https=)
CN (1) CN100439394C (https=)
AU (1) AU2002256803B2 (https=)
CA (1) CA2448963A1 (https=)
GB (1) GB0112687D0 (https=)
WO (1) WO2002096467A2 (https=)

Families Citing this family (17)

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US7192596B2 (en) * 1996-08-23 2007-03-20 The Health Protection Agency Ipsen Limited Recombinant toxin fragments
GB9617671D0 (en) * 1996-08-23 1996-10-02 Microbiological Res Authority Recombinant toxin fragments
US8012491B2 (en) * 1996-08-23 2011-09-06 Syntaxin, Ltd. Recombinant toxin fragments
US7601351B1 (en) 2002-06-26 2009-10-13 Human Genome Sciences, Inc. Antibodies against protective antigen
US6991789B2 (en) * 2004-06-29 2006-01-31 Allergas, Inc. Methods of modulating intracellular degradation rates of toxins
DE102004035606A1 (de) * 2004-07-22 2006-03-30 Biotecon Therapeutics Gmbh Carrier für Arzneimittel zur Gewinnung der oralen Bioverfügbarkeit
WO2006137836A2 (en) * 2004-08-17 2006-12-28 Research Development Foundation Bacterial vector systems
US20090092652A1 (en) * 2004-08-20 2009-04-09 Children's Medical Center Corporation Method for the inhibition of angiogenesis or cancer using protective antigen related molecules
AU2006233929B2 (en) * 2005-04-11 2012-05-31 Yeda Research And Development Co.Ltd. Chimeric proteins comprising Yersinia Yop, their preparation and pharmaceutical compositions containing them
DE102005019302A1 (de) * 2005-04-26 2006-11-16 Toxogen Gmbh Carrier zum Targeting von Nervenzellen
JP5714692B2 (ja) * 2010-03-23 2015-05-07 イーエムベーアー−インスティトゥート・フューア・モレクラレ・ビオテヒノロギー・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＩｍｂａ−Ｉｎｓｔｉｔｕｔ Ｆｕｅｒｍｏｌｅｋｕｌａｒｅ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅ Ｇｍｂｈ Ｉｉｉ型分泌機構の阻害剤の同定方法
WO2012054693A1 (en) * 2010-10-22 2012-04-26 Trudeau Institute Uses of yersinia yope peptide, gene, and subparts thereof as a plague vaccine component and assays for yersinia pestis-specific t cells
CN102807621B (zh) 2011-06-01 2016-04-13 厦门大学 包含白喉毒素无毒突变体crm197或其片段的融合蛋白
CN108137654A (zh) * 2015-05-15 2018-06-08 内布拉斯加大学董事会 适用于将分子递送进入选定细胞的工程改造的肉毒梭菌毒素
GB201609216D0 (en) 2016-05-25 2016-07-06 Evox Therapeutics And Isis Innovation Ltd Exosomes comprising therapeutic polypeptides
US20210054033A1 (en) * 2018-01-25 2021-02-25 The Wistar Institute Of Anatomy And Biology Methods and compositions for use of recombinant bacterial effector proteins as anti-inflammatory agents
WO2022087856A1 (zh) * 2020-10-26 2022-05-05 南京吉芮康生物科技研究院有限公司 一种减毒沙门氏菌分泌表达rbd结构域蛋白的新型冠状病毒疫苗抗原递呈系统及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2498192A2 (fr) * 1981-01-22 1982-07-23 Pasteur Institut Nouveau compose polypeptidique thiole provenant d'un fragment de la toxine tetanique, son procede d'obtention et ses applications
WO1983003971A1 (en) * 1982-05-12 1983-11-24 President And Fellows Of Harvard College Hybrid proteins
US5668255A (en) * 1984-06-07 1997-09-16 Seragen, Inc. Hybrid molecules having translocation region and cell-binding region
EP0760681B1 (en) * 1994-05-31 1999-09-01 Allergan, Inc Modification of clostridial toxins for use as transport proteins
US5614191A (en) * 1995-03-15 1997-03-25 The United States Of America As Represented By The Department Of Health And Human Services IL-13 receptor specific chimeric proteins and uses thereof
US5972899A (en) * 1996-01-25 1999-10-26 New York University Apoptosis induced by Shigella IpaB
SE9702191D0 (sv) * 1997-06-09 1997-06-09 Sven Pettersson Coposition and methods for the treatment of inflammatory dideases
US5965381A (en) * 1998-03-06 1999-10-12 Ludwig Institute For Cancer Research Delivery of proteins into eukaryotic cells with recombinant yersinia
US6485977B1 (en) * 1999-09-13 2002-11-26 Cornell Research Foundation, Inc. Recombinant constructs and techniques for delivering to eucaryotic cells bacterial proteins that are secreted via type III secretion systems

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