JP2004532849A5 - - Google Patents

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Publication number
JP2004532849A5
JP2004532849A5 JP2002583620A JP2002583620A JP2004532849A5 JP 2004532849 A5 JP2004532849 A5 JP 2004532849A5 JP 2002583620 A JP2002583620 A JP 2002583620A JP 2002583620 A JP2002583620 A JP 2002583620A JP 2004532849 A5 JP2004532849 A5 JP 2004532849A5
Authority
JP
Japan
Prior art keywords
composition
polynucleotide
tissue
agent
nervous system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002583620A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004532849A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/012527 external-priority patent/WO2002086105A1/en
Publication of JP2004532849A publication Critical patent/JP2004532849A/ja
Publication of JP2004532849A5 publication Critical patent/JP2004532849A5/ja
Pending legal-status Critical Current

Links

JP2002583620A 2001-04-20 2002-04-19 中枢神経系へのポリヌクレオチド薬剤の送達 Pending JP2004532849A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28531901P 2001-04-20 2001-04-20
US28871601P 2001-05-04 2001-05-04
PCT/US2002/012527 WO2002086105A1 (en) 2001-04-20 2002-04-19 Delivery of polynucleotide agents to the central nervous sysstem

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008282272A Division JP2009067805A (ja) 2001-04-20 2008-10-31 中枢神経系へのポリヌクレオチド薬剤の送達

Publications (2)

Publication Number Publication Date
JP2004532849A JP2004532849A (ja) 2004-10-28
JP2004532849A5 true JP2004532849A5 (enExample) 2005-12-22

Family

ID=26963130

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002583620A Pending JP2004532849A (ja) 2001-04-20 2002-04-19 中枢神経系へのポリヌクレオチド薬剤の送達
JP2008282272A Withdrawn JP2009067805A (ja) 2001-04-20 2008-10-31 中枢神経系へのポリヌクレオチド薬剤の送達

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008282272A Withdrawn JP2009067805A (ja) 2001-04-20 2008-10-31 中枢神経系へのポリヌクレオチド薬剤の送達

Country Status (4)

Country Link
US (3) US20030165434A1 (enExample)
EP (1) EP1385937A4 (enExample)
JP (2) JP2004532849A (enExample)
WO (1) WO2002086105A1 (enExample)

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US9216161B2 (en) 2004-08-13 2015-12-22 Healthpartners Research Foundation Methods of treating Huntington's disease comprising administering metal chelators to the upper one-third of the nasal cavity
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EP2640461B1 (en) 2010-11-16 2019-06-19 The Board Of Trustees Of The Leland Stanford Junior University Systems for treatment of dry eye
US9821159B2 (en) 2010-11-16 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Stimulation devices and methods
US8609088B2 (en) 2011-05-10 2013-12-17 Regents Of The University Of Minnesota Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
WO2012174481A1 (en) 2011-06-15 2012-12-20 Nerve Access, Inc. Pharmaceutical compositions for intranasal administration for the treatment of neurodegenerative disorders
EP3628325A1 (en) * 2011-07-22 2020-04-01 The University of Chicago Treatments for migraine and related disorders
EP2822600A4 (en) * 2012-03-09 2016-04-06 Univ Northeastern METHOD OF DISTRIBUTING NUCLEIC ACID ANOPARTICLES TO THE CENTRAL NERVOUS SYSTEM FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM
US10279012B2 (en) 2013-03-11 2019-05-07 Healthpartners Research & Education Methods of treating and preventing social communication disorder in patients by intranasal administration of insulin
EP2967817B1 (en) 2013-03-12 2021-03-10 Oculeve, Inc. Implant delivery devices and systems
HK1220934A1 (zh) 2013-04-19 2017-05-19 Oculeve, Inc. 鼻刺激装置和方法
HK1222093A1 (zh) 2013-05-15 2017-06-23 明尼苏达大学董事会 腺相关病毒介导的基因向中枢神经系统转移
EP3110405B1 (en) 2014-02-25 2020-05-06 Oculeve, Inc. Polymer formulations for nasolacrimal stimulation
US10314911B2 (en) 2014-04-08 2019-06-11 Healthpartners Research & Education Methods for protecting and treating traumatic brain injury, concussion and brain inflammation with intranasal insulin
EP3673952A1 (en) 2014-07-25 2020-07-01 Oculeve, Inc. Stimulation patterns for treating dry eye
WO2016065213A1 (en) 2014-10-22 2016-04-28 Oculeve, Inc. Implantable nasal stimulator systems and methods
AU2015335772B2 (en) 2014-10-22 2020-07-09 Oculeve, Inc. Contact lens for increasing tear production
WO2016065215A1 (en) 2014-10-22 2016-04-28 Oculeve, Inc. Stimulation devices and methods for treating dry eye
SG11201705591PA (en) 2015-01-07 2017-08-30 Trigemina Inc Magnesium-containing oxytocin formulations and methods of use
US10335435B2 (en) 2015-05-22 2019-07-02 Marco Merida Method for endoscopically delivering stem cells to the brain using an intranasal, injectable approach
US10426958B2 (en) 2015-12-04 2019-10-01 Oculeve, Inc. Intranasal stimulation for enhanced release of ocular mucins and other tear proteins
US10252048B2 (en) 2016-02-19 2019-04-09 Oculeve, Inc. Nasal stimulation for rhinitis, nasal congestion, and ocular allergies
HRP20250215T1 (hr) 2016-04-12 2025-06-20 Tonix Pharma Limited Formulacije oksitocina koje sadrže magnezij i postupci upotrebe
SG11201808176TA (en) 2016-04-15 2018-10-30 The Trustees Of The Univ Of Pennsyvania Gene therapy for treating mucopolysaccharidosis type ii
AU2017260237A1 (en) 2016-05-02 2018-11-22 Oculeve, Inc. Intranasal stimulation for treatment of meibomian gland disease and blepharitis
US10610095B2 (en) 2016-12-02 2020-04-07 Oculeve, Inc. Apparatus and method for dry eye forecast and treatment recommendation
CN109498832B (zh) * 2017-09-15 2021-10-08 中国药科大学 一种交联多孔止血微球及其制备方法
CA3076036A1 (en) 2017-09-22 2019-03-28 The Trustees Of The University Of Pennsylvania Gene therapy for treating mucopolysaccharidosis type ii
JP2022547948A (ja) 2019-09-09 2022-11-16 ザ・ユニバーシティ・オブ・シカゴ 片頭痛の処置のための併用療法
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JP2023181674A (ja) * 2022-06-13 2023-12-25 国立大学法人 東京大学 核酸とカチオン性ポリマーとのポリイオンコンプレックスであって、正の表面電位を有し、核酸を脳組織に送達することができるポリイオンコンプレックス

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AU2582197A (en) * 1996-03-15 1997-10-01 Start Technology Partnership Methods and compositions for diagnosis and treatment of pathological conditions related to abnormal dopamine receptor expression
US5814500A (en) * 1996-10-31 1998-09-29 The Johns Hopkins University School Of Medicine Delivery construct for antisense nucleic acids and methods of use
IL131212A0 (en) * 1999-08-03 2001-01-28 Yissum Res Dev Co Recombinant virus and live-virus vaccines

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