JP2004532289A5 - - Google Patents

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Publication number
JP2004532289A5
JP2004532289A5 JP2002565549A JP2002565549A JP2004532289A5 JP 2004532289 A5 JP2004532289 A5 JP 2004532289A5 JP 2002565549 A JP2002565549 A JP 2002565549A JP 2002565549 A JP2002565549 A JP 2002565549A JP 2004532289 A5 JP2004532289 A5 JP 2004532289A5
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JP
Japan
Prior art keywords
group
independently
substituted
compound
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002565549A
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English (en)
Japanese (ja)
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JP2004532289A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/004781 external-priority patent/WO2002065988A2/en
Publication of JP2004532289A publication Critical patent/JP2004532289A/ja
Publication of JP2004532289A5 publication Critical patent/JP2004532289A5/ja
Pending legal-status Critical Current

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JP2002565549A 2001-02-20 2002-02-19 末端分枝高分子リンカーおよびそれを含む高分子複合体 Pending JP2004532289A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27000901P 2001-02-20 2001-02-20
PCT/US2002/004781 WO2002065988A2 (en) 2001-02-20 2002-02-19 Terminally-branched polymeric linkers and polymeric conjugates containing the same

Publications (2)

Publication Number Publication Date
JP2004532289A JP2004532289A (ja) 2004-10-21
JP2004532289A5 true JP2004532289A5 (OSRAM) 2005-12-22

Family

ID=23029515

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002565549A Pending JP2004532289A (ja) 2001-02-20 2002-02-19 末端分枝高分子リンカーおよびそれを含む高分子複合体

Country Status (10)

Country Link
US (1) US20020183259A1 (OSRAM)
EP (1) EP1362053B1 (OSRAM)
JP (1) JP2004532289A (OSRAM)
AT (1) ATE378342T1 (OSRAM)
AU (1) AU2002251988A1 (OSRAM)
CA (1) CA2437989A1 (OSRAM)
DE (1) DE60223499T2 (OSRAM)
DK (1) DK1362053T3 (OSRAM)
MX (1) MXPA03007392A (OSRAM)
WO (1) WO2002065988A2 (OSRAM)

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PT2279758E (pt) 2005-06-16 2015-05-27 Nektar Therapeutics Conjugados possuindo uma ligação degradável e reagentes poliméricos úteis na preparação de tais conjugados
JP5249016B2 (ja) 2006-03-28 2013-07-31 日本化薬株式会社 タキサン類の高分子結合体
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WO2008041610A1 (fr) * 2006-10-03 2008-04-10 Nippon Kayaku Kabushiki Kaisha Mélange d'un dérivé de résorcinol avec un polymère
EP2080779B1 (en) 2006-11-06 2016-05-18 Nippon Kayaku Kabushiki Kaisha Polymeric derivative of nucleic acid metabolic antagonist
EP2090607B1 (en) * 2006-11-08 2015-05-20 Nippon Kayaku Kabushiki Kaisha Polymeric derivative of nucleic acid metabolic antagonist
CA2676820A1 (en) 2007-01-31 2008-08-07 Affymax, Inc. Nitrogen-based linkers for attaching modifying groups to polypeptides and other macromolecules
USRE46190E1 (en) 2007-09-28 2016-11-01 Nippon Kayaku Kabushiki Kaisha High-molecular weight conjugate of steroids
JP5687899B2 (ja) * 2008-03-18 2015-03-25 日本化薬株式会社 生理活性物質の高分子結合体
WO2009136572A1 (ja) 2008-05-08 2009-11-12 日本化薬株式会社 葉酸若しくは葉酸誘導体の高分子結合体
EP2431403B1 (en) 2009-05-15 2016-09-28 Nipponkayaku Kabushikikaisha Polymer conjugate of bioactive substance having hydroxy group
PE20140636A1 (es) 2010-09-30 2014-06-18 Astrazeneca Ab Conjugado de naloxol-peg cristalino
WO2012067138A1 (ja) 2010-11-17 2012-05-24 日本化薬株式会社 新規なシチジン系代謝拮抗剤の高分子誘導体
EP2741778A1 (en) * 2011-08-12 2014-06-18 Ascendis Pharma A/S Polymeric hyperbranched carrier-linked prodrugs
ES2635117T3 (es) 2011-09-11 2017-10-02 Nippon Kayaku Kabushiki Kaisha Método para la fabricación de un copolímero de bloques
EP3820879B1 (en) 2018-06-29 2024-11-06 Changchun Changcheng Pharmaceutical Technology Co., LTD Phosphorus-containing prodrugs of gemcitabine

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