JP2004527534A - ニコチン性アセチルコリン受容体リガンド - Google Patents
ニコチン性アセチルコリン受容体リガンド Download PDFInfo
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- JP2004527534A JP2004527534A JP2002581397A JP2002581397A JP2004527534A JP 2004527534 A JP2004527534 A JP 2004527534A JP 2002581397 A JP2002581397 A JP 2002581397A JP 2002581397 A JP2002581397 A JP 2002581397A JP 2004527534 A JP2004527534 A JP 2004527534A
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- formula
- azabicyclo
- benzyl
- group
- hept
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108050006807 Nicotinic acetylcholine receptors Proteins 0.000 title claims abstract description 12
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- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 15
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10118551A DE10118551A1 (de) | 2001-04-14 | 2001-04-14 | Nikotinische Acetylcholinrezeptor Liganden |
| PCT/EP2002/002729 WO2002083640A1 (de) | 2001-04-14 | 2002-03-13 | Nikotinische acetylcholinrezeptor liganden |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004527534A true JP2004527534A (ja) | 2004-09-09 |
| JP2004527534A5 JP2004527534A5 (enExample) | 2005-12-22 |
Family
ID=7681551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002581397A Withdrawn JP2004527534A (ja) | 2001-04-14 | 2002-03-13 | ニコチン性アセチルコリン受容体リガンド |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20040110788A1 (enExample) |
| EP (1) | EP1379502A1 (enExample) |
| JP (1) | JP2004527534A (enExample) |
| AR (1) | AR033156A1 (enExample) |
| CA (1) | CA2443577A1 (enExample) |
| CZ (1) | CZ20032999A3 (enExample) |
| DE (1) | DE10118551A1 (enExample) |
| HU (1) | HUP0303980A3 (enExample) |
| SK (1) | SK13722003A3 (enExample) |
| WO (1) | WO2002083640A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0400970D0 (sv) * | 2004-04-14 | 2004-04-14 | Astrazeneca Ab | Nicotinic acetylcholine receptor ligands |
| WO2007110782A1 (en) * | 2005-12-30 | 2007-10-04 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9020051D0 (en) * | 1990-09-13 | 1990-10-24 | Pfizer Ltd | Muscarinic receptor antagonists |
| WO1998048801A1 (en) * | 1997-04-26 | 1998-11-05 | Sumitomo Pharmaceuticals Co., Ltd. | 2-azabicyclo compounds |
| GB9822945D0 (en) * | 1998-10-20 | 1998-12-16 | Isis Innovations Ltd | Epibatidine analogues |
| DE10044905A1 (de) * | 2000-09-12 | 2002-03-21 | Merck Patent Gmbh | (2-Azabicyclo[2.2.1]hept-7-yl)methanol-Derivate als nikontinische Acetylcholinrezeptor Agonisten |
-
2001
- 2001-04-14 DE DE10118551A patent/DE10118551A1/de not_active Withdrawn
-
2002
- 2002-03-13 SK SK1372-2003A patent/SK13722003A3/sk unknown
- 2002-03-13 JP JP2002581397A patent/JP2004527534A/ja not_active Withdrawn
- 2002-03-13 US US10/474,801 patent/US20040110788A1/en not_active Abandoned
- 2002-03-13 EP EP02732477A patent/EP1379502A1/de not_active Withdrawn
- 2002-03-13 CA CA002443577A patent/CA2443577A1/en not_active Abandoned
- 2002-03-13 WO PCT/EP2002/002729 patent/WO2002083640A1/de not_active Ceased
- 2002-03-13 CZ CZ20032999A patent/CZ20032999A3/cs unknown
- 2002-03-13 HU HU0303980A patent/HUP0303980A3/hu unknown
- 2002-04-12 AR ARP020101346A patent/AR033156A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1379502A1 (de) | 2004-01-14 |
| HUP0303980A2 (hu) | 2004-04-28 |
| CZ20032999A3 (cs) | 2004-02-18 |
| WO2002083640A1 (de) | 2002-10-24 |
| AR033156A1 (es) | 2003-12-03 |
| HUP0303980A3 (en) | 2005-09-28 |
| US20040110788A1 (en) | 2004-06-10 |
| DE10118551A1 (de) | 2002-10-17 |
| SK13722003A3 (sk) | 2004-02-03 |
| CA2443577A1 (en) | 2002-10-24 |
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| Date | Code | Title | Description |
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