JP2004526701A5 - - Google Patents
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- Publication number
- JP2004526701A5 JP2004526701A5 JP2002562378A JP2002562378A JP2004526701A5 JP 2004526701 A5 JP2004526701 A5 JP 2004526701A5 JP 2002562378 A JP2002562378 A JP 2002562378A JP 2002562378 A JP2002562378 A JP 2002562378A JP 2004526701 A5 JP2004526701 A5 JP 2004526701A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkoxy
- group
- ile
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003545 alkoxy group Chemical group 0.000 claims 8
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 229940024606 amino acid Drugs 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 5
- 125000005843 halogen group Chemical group 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- 208000014674 injury Diseases 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 claims 1
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 claims 1
- 241000024188 Andala Species 0.000 claims 1
- 208000005374 Poisoning Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- -1 cinnamoyl group Chemical group 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 208000028867 ischemia Diseases 0.000 claims 1
- 231100000572 poisoning Toxicity 0.000 claims 1
- 230000000607 poisoning effect Effects 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10105040A DE10105040A1 (de) | 2001-02-05 | 2001-02-05 | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
| PCT/EP2002/001182 WO2002062372A2 (en) | 2001-02-05 | 2002-02-05 | Tripeptide derivatives for the treatment of postlesional diseases of the nervous system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004526701A JP2004526701A (ja) | 2004-09-02 |
| JP2004526701A5 true JP2004526701A5 (cg-RX-API-DMAC7.html) | 2005-12-22 |
Family
ID=7672833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002562378A Pending JP2004526701A (ja) | 2001-02-05 | 2002-02-05 | 神経系の損傷後疾患の処置のためのトリペプチド誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7163922B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1390055B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2004526701A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE310529T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002238532A1 (cg-RX-API-DMAC7.html) |
| DE (2) | DE10105040A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1390055T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2250617T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002062372A2 (cg-RX-API-DMAC7.html) |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU599809B2 (en) * | 1987-05-20 | 1990-07-26 | Zambon Group S.P.A. | Isoxazoles with nootropic activity |
| CA1323301C (en) | 1987-06-05 | 1993-10-19 | Alan I. Faden | Thyrotropin-releasing hormone analogs in cns injury |
| FR2622581B1 (fr) * | 1987-11-03 | 1990-02-16 | Inorgan Sa Rech Develop Pharm | Nouveaux derives de l-proline, leur preparation et leurs applications biologiques |
| HU904967D0 (en) * | 1988-04-22 | 1991-01-28 | Hoechst Ag | Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives |
| DE4007869A1 (de) | 1990-03-13 | 1991-09-19 | Merck Patent Gmbh | Aminosaeurederivate |
| JPH045240A (ja) | 1990-04-20 | 1992-01-09 | Taisho Pharmaceut Co Ltd | 抗痴呆剤 |
| JPH06504061A (ja) | 1990-12-28 | 1994-05-12 | コーテックス ファーマシューティカルズ インコーポレイテッド | 神経変性の治療および予防におけるカルパイン阻害剤の使用 |
| WO1992013549A1 (en) * | 1991-02-07 | 1992-08-20 | Research Corporation Technologies, Inc. | Inhibition of cell proliferation by hydrophobic peptides |
| US6235929B1 (en) * | 1991-12-27 | 2001-05-22 | Georgia Tech Research Corporation | Tripeptide α-ketoamides |
| US5716929A (en) * | 1994-06-17 | 1998-02-10 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
| US5834029A (en) * | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
| EP0840614A1 (en) | 1995-06-13 | 1998-05-13 | Sanofi Winthrop, Inc. | Calpain inhibitors for the treatment of neurodegenerative diseases |
| US5840838A (en) * | 1996-02-29 | 1998-11-24 | University Of Kentucky Research Foundation | Process for enhancing the activity of amyloid β peptides |
| JP2001501930A (ja) | 1996-10-04 | 2001-02-13 | オークランド ユニサーヴィスィズ リミテッド | 神経酵素の調節 |
| JP4727770B2 (ja) * | 1997-09-26 | 2011-07-20 | カルピス株式会社 | 尿中カテコールアミン低下、尿中ノルアドレナリン低下、尿中ドーパミン低下及びＦｉｓｃｈｅｒ比低下の少なくとも１つの軽減剤 |
| US6080848A (en) * | 1998-05-01 | 2000-06-27 | Incyte Pharmaceuticals, Inc. | Human brain associated protein |
| US6379691B1 (en) * | 1998-09-29 | 2002-04-30 | Medtronic/Ave, Inc. | Uses for medical devices having a lubricious, nitric oxide-releasing coating |
| AU1574701A (en) * | 1999-10-22 | 2001-04-30 | Wrair Walter Reed Army Institute Of Research | A pharmaceutical composition containing pglu-glu-pro-nh2 and method for treating diseases and injuries to the brain, spinal cord and retina using same |
| JP4633876B2 (ja) * | 1999-11-11 | 2011-02-16 | カルピス株式会社 | トリペプチドの製造方法 |
| WO2001068114A1 (en) | 2000-03-10 | 2001-09-20 | Monsanto Company | Novel peptides with anti-hypertensive activity |
| DE10105041A1 (de) * | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
| DE10105038B4 (de) * | 2001-02-05 | 2005-07-07 | Neurotell Ag | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
-
2001
- 2001-02-05 DE DE10105040A patent/DE10105040A1/de not_active Ceased
-
2002
- 2002-02-05 AU AU2002238532A patent/AU2002238532A1/en not_active Abandoned
- 2002-02-05 JP JP2002562378A patent/JP2004526701A/ja active Pending
- 2002-02-05 DE DE60207550T patent/DE60207550T2/de not_active Expired - Lifetime
- 2002-02-05 DK DK02704686T patent/DK1390055T3/da active
- 2002-02-05 EP EP02704686A patent/EP1390055B1/en not_active Expired - Lifetime
- 2002-02-05 ES ES02704686T patent/ES2250617T3/es not_active Expired - Lifetime
- 2002-02-05 AT AT02704686T patent/ATE310529T1/de not_active IP Right Cessation
- 2002-02-05 WO PCT/EP2002/001182 patent/WO2002062372A2/en not_active Ceased
-
2003
- 2003-08-05 US US10/635,808 patent/US7163922B2/en not_active Expired - Fee Related