JP2004525928A - ニコチン含有経口剤形 - Google Patents

ニコチン含有経口剤形 Download PDF

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Publication number
JP2004525928A
JP2004525928A JP2002574739A JP2002574739A JP2004525928A JP 2004525928 A JP2004525928 A JP 2004525928A JP 2002574739 A JP2002574739 A JP 2002574739A JP 2002574739 A JP2002574739 A JP 2002574739A JP 2004525928 A JP2004525928 A JP 2004525928A
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JP
Japan
Prior art keywords
nicotine
dosage form
active
sugar alcohol
oral administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002574739A
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English (en)
Japanese (ja)
Other versions
JP2004525928A5 (https=
Inventor
ジョン・リウ
スタンリー・ジェイ・レッチ
スチュアート・プラットカウ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JP2004525928A publication Critical patent/JP2004525928A/ja
Publication of JP2004525928A5 publication Critical patent/JP2004525928A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addiction (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2002574739A 2001-03-26 2002-03-22 ニコチン含有経口剤形 Pending JP2004525928A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27860601P 2001-03-26 2001-03-26
PCT/US2002/008914 WO2002076211A1 (en) 2001-03-26 2002-03-22 Nicotine-containing oral dosage form

Publications (2)

Publication Number Publication Date
JP2004525928A true JP2004525928A (ja) 2004-08-26
JP2004525928A5 JP2004525928A5 (https=) 2005-12-22

Family

ID=23065632

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002574739A Pending JP2004525928A (ja) 2001-03-26 2002-03-22 ニコチン含有経口剤形

Country Status (11)

Country Link
EP (1) EP1372392A4 (https=)
JP (1) JP2004525928A (https=)
CN (2) CN101301275A (https=)
AR (1) AR033444A1 (https=)
AU (1) AU2002252470B2 (https=)
BR (1) BR0208382A (https=)
CA (1) CA2440713A1 (https=)
MX (1) MXPA03008762A (https=)
NZ (1) NZ528167A (https=)
PL (1) PL364621A1 (https=)
WO (1) WO2002076211A1 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013528588A (ja) * 2010-05-07 2013-07-11 ニコノバム・ユー・エス・エイ・インコーポレイテツド ニコチン含有医薬組成物
JP2014526278A (ja) * 2011-09-22 2014-10-06 アール・ジエイ・レイノルズ・タバコ・カンパニー 半透明無煙タバコ製品
JP2015516153A (ja) * 2012-04-17 2015-06-11 アール・ジエイ・レイノルズ・タバコ・カンパニー 再融解摂取製品
JP2022535586A (ja) * 2019-06-07 2022-08-09 エヌシーピー ネクストジェン アクティーゼルスカブ ニコチンパウチ組成物
JP2024513464A (ja) * 2021-04-06 2024-03-25 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー 口腔用製品に含有させるための噴霧乾燥ニコチン
JP2024515559A (ja) * 2021-04-06 2024-04-10 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー カプセル化ニコチン顆粒及びその調製方法

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040253307A1 (en) * 2003-02-04 2004-12-16 Brian Hague Sugar-free oral transmucosal solid dosage forms and uses thereof
US9119846B2 (en) 2003-04-29 2015-09-01 Neurim Pharmaceuticals (1991) Ltd. Method and composition for enhancing cognition in alzheimer's patients
IL155666A (en) 2003-04-29 2013-12-31 Neurim Pharma 1991 Insomnia treatment
BRPI0412752B8 (pt) * 2003-07-24 2021-05-25 Glaxosmithkline Llc composição de filme de dissolução oral
GB0320854D0 (en) 2003-09-05 2003-10-08 Arrow No 7 Ltd Buccal drug delivery
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
CN104397869B (zh) 2003-11-07 2016-06-08 美国无烟烟草有限责任公司 烟草组合物
US8101208B2 (en) * 2004-08-11 2012-01-24 Kraft Foods Global Brands Llc Sensate compositions and delivery systems therefor
AU2005284908B2 (en) 2004-09-13 2011-12-08 Morningside Venture Investments Limited Biosynchronous transdermal drug delivery
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
BRPI0719428A2 (pt) * 2006-12-01 2014-02-25 Cima Labs Inc Forma de dosagem transmucosal oral sólida, método para tratar dependência de nicotina em um receptor que deseja tal tratamento, sistema de distribuição de nicotina transmucosal oral, e, método de substituíção de nicotina.
CN103977003A (zh) 2007-04-02 2014-08-13 帕金森氏病研究院 用于降低治疗的副作用的方法和组合物
GB2468424B (en) * 2007-04-02 2011-11-09 Parkinson S Inst Methods and compositions for reduction of side effects of therapeutic treatments
DE102008012015A1 (de) * 2008-03-01 2009-09-10 Südzucker AG Mannheim/Ochsenfurt Verbesserte Isomalt-haltige Komprimate und Verfahren zu ihrer Herstellung
CN102770138B (zh) * 2010-02-18 2015-12-09 J·V·达卡 含有尼古丁的软凝胶锭剂
UA112974C2 (uk) 2010-09-16 2016-11-25 Джеі. Бі. Кемікалс Енд Фармасьютікалс Лімітид Нікотиновмісна композиція (варіанти)
WO2013006643A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
AR096223A1 (es) * 2013-05-10 2015-12-16 Glaxosmithkline Llc Pastilla de nicotina para administración oral
CN104132895B (zh) * 2014-07-08 2017-08-25 国家烟草质量监督检验中心 适用于连续流动法测定烟草及烟草制品中总植物碱的缓冲体系
AU2016211330A1 (en) 2015-01-28 2017-08-03 Chrono Therapeutics Inc. Drug delivery methods and systems
US10679516B2 (en) 2015-03-12 2020-06-09 Morningside Venture Investments Limited Craving input and support system
CA3049529A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
SE541358C2 (en) * 2017-05-30 2019-08-13 Enorama Pharma Ab Nicotine-containing chewing gum compositions
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems
US12397141B2 (en) 2018-11-16 2025-08-26 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
WO2021144367A1 (en) * 2020-01-15 2021-07-22 Mcneil Ab Lozenge
USD1081739S1 (en) 2021-04-06 2025-07-01 Altria Client Services Llc Die for gum forming
US12295412B2 (en) 2022-01-28 2025-05-13 Altria Client Services Llc Oral pouch product

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9310412D0 (en) * 1993-05-20 1993-07-07 Danbiosyst Uk Nasal nicotine system
US5549906A (en) * 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
DE19536394A1 (de) * 1995-09-29 1997-04-03 Basf Ag Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze
DE19639342C2 (de) * 1996-09-25 1998-07-16 Suedzucker Ag Kaugummi, enthaltend ein Süßungsmittel
US6322806B1 (en) * 1999-04-06 2001-11-27 Wm. Wrigley Jr. Company Over-coated chewing gum formulations including tableted center

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013528588A (ja) * 2010-05-07 2013-07-11 ニコノバム・ユー・エス・エイ・インコーポレイテツド ニコチン含有医薬組成物
JP2014526278A (ja) * 2011-09-22 2014-10-06 アール・ジエイ・レイノルズ・タバコ・カンパニー 半透明無煙タバコ製品
JP2015516153A (ja) * 2012-04-17 2015-06-11 アール・ジエイ・レイノルズ・タバコ・カンパニー 再融解摂取製品
JP2022535586A (ja) * 2019-06-07 2022-08-09 エヌシーピー ネクストジェン アクティーゼルスカブ ニコチンパウチ組成物
JP7682812B2 (ja) 2019-06-07 2025-05-26 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム ニコチンパウチ組成物
JP2025122038A (ja) * 2019-06-07 2025-08-20 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム ニコチンパウチ組成物
JP2024513464A (ja) * 2021-04-06 2024-03-25 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー 口腔用製品に含有させるための噴霧乾燥ニコチン
JP2024515559A (ja) * 2021-04-06 2024-04-10 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー カプセル化ニコチン顆粒及びその調製方法
JP7789800B2 (ja) 2021-04-06 2025-12-22 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー カプセル化ニコチン顆粒及びその調製方法
JP7789799B2 (ja) 2021-04-06 2025-12-22 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー 口腔用製品に含有させるための噴霧乾燥ニコチン

Also Published As

Publication number Publication date
EP1372392A1 (en) 2004-01-02
CN1553771A (zh) 2004-12-08
CA2440713A1 (en) 2002-10-03
CN101301275A (zh) 2008-11-12
MXPA03008762A (es) 2004-02-18
EP1372392A4 (en) 2004-06-23
AR033444A1 (es) 2003-12-17
PL364621A1 (en) 2004-12-13
BR0208382A (pt) 2004-06-15
WO2002076211A1 (en) 2002-10-03
AU2002252470B2 (en) 2008-05-22
NZ528167A (en) 2005-04-29

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