AU2002252470B2 - Nicotine-containing oral dosage form - Google Patents

Nicotine-containing oral dosage form Download PDF

Info

Publication number
AU2002252470B2
AU2002252470B2 AU2002252470A AU2002252470A AU2002252470B2 AU 2002252470 B2 AU2002252470 B2 AU 2002252470B2 AU 2002252470 A AU2002252470 A AU 2002252470A AU 2002252470 A AU2002252470 A AU 2002252470A AU 2002252470 B2 AU2002252470 B2 AU 2002252470B2
Authority
AU
Australia
Prior art keywords
nicotine
dosage form
form according
active
buffer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002252470A
Other languages
English (en)
Other versions
AU2002252470A1 (en
Inventor
Stanley J. Lech
John Liu
Stuart Platcow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
GlaxoSmithKline LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline LLC filed Critical GlaxoSmithKline LLC
Publication of AU2002252470A1 publication Critical patent/AU2002252470A1/en
Priority to AU2008202048A priority Critical patent/AU2008202048A1/en
Application granted granted Critical
Publication of AU2002252470B2 publication Critical patent/AU2002252470B2/en
Assigned to GLAXOSMITHKLINE LLC reassignment GLAXOSMITHKLINE LLC Request to Amend Deed and Register Assignors: SMITHKLINE BEECHAM CORPORATION
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addiction (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU2002252470A 2001-03-26 2002-03-22 Nicotine-containing oral dosage form Ceased AU2002252470B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2008202048A AU2008202048A1 (en) 2001-03-26 2008-05-08 Nicotine-containing oral dosage form

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27860601P 2001-03-26 2001-03-26
US60/278,606 2001-03-26
PCT/US2002/008914 WO2002076211A1 (en) 2001-03-26 2002-03-22 Nicotine-containing oral dosage form

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2008202048A Division AU2008202048A1 (en) 2001-03-26 2008-05-08 Nicotine-containing oral dosage form

Publications (2)

Publication Number Publication Date
AU2002252470A1 AU2002252470A1 (en) 2003-03-27
AU2002252470B2 true AU2002252470B2 (en) 2008-05-22

Family

ID=23065632

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002252470A Ceased AU2002252470B2 (en) 2001-03-26 2002-03-22 Nicotine-containing oral dosage form

Country Status (11)

Country Link
EP (1) EP1372392A4 (https=)
JP (1) JP2004525928A (https=)
CN (2) CN101301275A (https=)
AR (1) AR033444A1 (https=)
AU (1) AU2002252470B2 (https=)
BR (1) BR0208382A (https=)
CA (1) CA2440713A1 (https=)
MX (1) MXPA03008762A (https=)
NZ (1) NZ528167A (https=)
PL (1) PL364621A1 (https=)
WO (1) WO2002076211A1 (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040253307A1 (en) * 2003-02-04 2004-12-16 Brian Hague Sugar-free oral transmucosal solid dosage forms and uses thereof
US9119846B2 (en) 2003-04-29 2015-09-01 Neurim Pharmaceuticals (1991) Ltd. Method and composition for enhancing cognition in alzheimer's patients
IL155666A (en) 2003-04-29 2013-12-31 Neurim Pharma 1991 Insomnia treatment
BRPI0412752B8 (pt) * 2003-07-24 2021-05-25 Glaxosmithkline Llc composição de filme de dissolução oral
GB0320854D0 (en) 2003-09-05 2003-10-08 Arrow No 7 Ltd Buccal drug delivery
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
CN104397869B (zh) 2003-11-07 2016-06-08 美国无烟烟草有限责任公司 烟草组合物
US8101208B2 (en) * 2004-08-11 2012-01-24 Kraft Foods Global Brands Llc Sensate compositions and delivery systems therefor
AU2005284908B2 (en) 2004-09-13 2011-12-08 Morningside Venture Investments Limited Biosynchronous transdermal drug delivery
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
BRPI0719428A2 (pt) * 2006-12-01 2014-02-25 Cima Labs Inc Forma de dosagem transmucosal oral sólida, método para tratar dependência de nicotina em um receptor que deseja tal tratamento, sistema de distribuição de nicotina transmucosal oral, e, método de substituíção de nicotina.
CN103977003A (zh) 2007-04-02 2014-08-13 帕金森氏病研究院 用于降低治疗的副作用的方法和组合物
GB2468424B (en) * 2007-04-02 2011-11-09 Parkinson S Inst Methods and compositions for reduction of side effects of therapeutic treatments
DE102008012015A1 (de) * 2008-03-01 2009-09-10 Südzucker AG Mannheim/Ochsenfurt Verbesserte Isomalt-haltige Komprimate und Verfahren zu ihrer Herstellung
CN102770138B (zh) * 2010-02-18 2015-12-09 J·V·达卡 含有尼古丁的软凝胶锭剂
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
UA112974C2 (uk) 2010-09-16 2016-11-25 Джеі. Бі. Кемікалс Енд Фармасьютікалс Лімітид Нікотиновмісна композиція (варіанти)
WO2013006643A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US9044035B2 (en) * 2012-04-17 2015-06-02 R.J. Reynolds Tobacco Company Remelted ingestible products
AR096223A1 (es) * 2013-05-10 2015-12-16 Glaxosmithkline Llc Pastilla de nicotina para administración oral
CN104132895B (zh) * 2014-07-08 2017-08-25 国家烟草质量监督检验中心 适用于连续流动法测定烟草及烟草制品中总植物碱的缓冲体系
AU2016211330A1 (en) 2015-01-28 2017-08-03 Chrono Therapeutics Inc. Drug delivery methods and systems
US10679516B2 (en) 2015-03-12 2020-06-09 Morningside Venture Investments Limited Craving input and support system
CA3049529A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
SE541358C2 (en) * 2017-05-30 2019-08-13 Enorama Pharma Ab Nicotine-containing chewing gum compositions
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems
US12397141B2 (en) 2018-11-16 2025-08-26 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
BR112021024354A2 (pt) * 2019-06-07 2022-01-11 Ncp Nextgen As Produto em bolsa oral e método para fabricar um produto em bolsa oral
WO2021144367A1 (en) * 2020-01-15 2021-07-22 Mcneil Ab Lozenge
US20220313614A1 (en) * 2021-04-06 2022-10-06 Altria Client Services Llc Encapsulated nicotine granules and methods of preparation thereof
USD1081739S1 (en) 2021-04-06 2025-07-01 Altria Client Services Llc Die for gum forming
US20220313678A1 (en) * 2021-04-06 2022-10-06 Altria Client Services Llc Spray dried nicotine for inclusion in oral products
US12295412B2 (en) 2022-01-28 2025-05-13 Altria Client Services Llc Oral pouch product

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593684A (en) * 1993-08-04 1997-01-14 Pharmacia Ab Method and therapeutic system for smoking cessation
US5662920A (en) * 1993-07-26 1997-09-02 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5935604A (en) * 1993-05-20 1999-08-10 Danbiosyst Uk Limited Nasal drug delivery composition containing nicotine
US6180143B1 (en) * 1996-09-25 2001-01-30 Sudzucker Akiengesellschaft Mannheim Ochsenfurt Chewing gum containing 1,1-GPS sweetener and process of preparing
US6187342B1 (en) * 1995-09-29 2001-02-13 Basf Aktiengesellschaft Solid medicaments obtained by extrusion of an isomalt-containing polymer-active substance melt
US6290985B2 (en) * 1999-04-06 2001-09-18 Wm. Wrigley, Jr. Company Over-coated chewing gum formulations including tableted center

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935604A (en) * 1993-05-20 1999-08-10 Danbiosyst Uk Limited Nasal drug delivery composition containing nicotine
US5662920A (en) * 1993-07-26 1997-09-02 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5593684A (en) * 1993-08-04 1997-01-14 Pharmacia Ab Method and therapeutic system for smoking cessation
US6187342B1 (en) * 1995-09-29 2001-02-13 Basf Aktiengesellschaft Solid medicaments obtained by extrusion of an isomalt-containing polymer-active substance melt
US6180143B1 (en) * 1996-09-25 2001-01-30 Sudzucker Akiengesellschaft Mannheim Ochsenfurt Chewing gum containing 1,1-GPS sweetener and process of preparing
US6290985B2 (en) * 1999-04-06 2001-09-18 Wm. Wrigley, Jr. Company Over-coated chewing gum formulations including tableted center

Also Published As

Publication number Publication date
JP2004525928A (ja) 2004-08-26
EP1372392A1 (en) 2004-01-02
CN1553771A (zh) 2004-12-08
CA2440713A1 (en) 2002-10-03
CN101301275A (zh) 2008-11-12
MXPA03008762A (es) 2004-02-18
EP1372392A4 (en) 2004-06-23
AR033444A1 (es) 2003-12-17
PL364621A1 (en) 2004-12-13
BR0208382A (pt) 2004-06-15
WO2002076211A1 (en) 2002-10-03
NZ528167A (en) 2005-04-29

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
HB Alteration of name in register

Owner name: GLAXOSMITHKLINE LLC

Free format text: FORMER NAME(S): SMITHKLINE BEECHAM CORPORATION

MK14 Patent ceased section 143(a) (annual fees not paid) or expired