JP2004525922A5 - - Google Patents

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Publication number
JP2004525922A5
JP2004525922A5 JP2002573034A JP2002573034A JP2004525922A5 JP 2004525922 A5 JP2004525922 A5 JP 2004525922A5 JP 2002573034 A JP2002573034 A JP 2002573034A JP 2002573034 A JP2002573034 A JP 2002573034A JP 2004525922 A5 JP2004525922 A5 JP 2004525922A5
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JP
Japan
Prior art keywords
component
light chain
agent
amino acid
heavy chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2002573034A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004525922A (ja
Filing date
Publication date
Priority claimed from US09/810,601 external-priority patent/US6831059B2/en
Application filed filed Critical
Publication of JP2004525922A publication Critical patent/JP2004525922A/ja
Publication of JP2004525922A5 publication Critical patent/JP2004525922A5/ja
Withdrawn legal-status Critical Current

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JP2002573034A 2001-03-15 2002-03-11 ゴナドトロピン関連疾患を治療するための組成物および方法 Withdrawn JP2004525922A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/810,601 US6831059B2 (en) 2000-10-20 2001-03-15 Compositions and methods for treating gonadotrophin related illnesses
PCT/US2002/007379 WO2002074327A2 (en) 2001-03-15 2002-03-11 Compositions and methods for treating gonadotrophin related illnesses

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010106073A Division JP2010174037A (ja) 2001-03-15 2010-05-06 ゴナドトロピン関連疾患を治療するための組成物および方法

Publications (2)

Publication Number Publication Date
JP2004525922A JP2004525922A (ja) 2004-08-26
JP2004525922A5 true JP2004525922A5 (enExample) 2005-12-22

Family

ID=25204201

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002573034A Withdrawn JP2004525922A (ja) 2001-03-15 2002-03-11 ゴナドトロピン関連疾患を治療するための組成物および方法
JP2010106073A Withdrawn JP2010174037A (ja) 2001-03-15 2010-05-06 ゴナドトロピン関連疾患を治療するための組成物および方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010106073A Withdrawn JP2010174037A (ja) 2001-03-15 2010-05-06 ゴナドトロピン関連疾患を治療するための組成物および方法

Country Status (4)

Country Link
US (1) US6831059B2 (enExample)
EP (1) EP1368053A4 (enExample)
JP (2) JP2004525922A (enExample)
WO (1) WO2002074327A2 (enExample)

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US7227010B2 (en) * 1993-09-21 2007-06-05 United States Of America As Represented By The Secretary Of The Army Recombinant light chains of botulinum neurotoxins and light chain fusion proteins for use in research and clinical therapy
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EP2267008B1 (en) * 1999-08-25 2014-07-02 Allergan, Inc. Activatable recombinant neurotoxins
US7838007B2 (en) 1999-12-07 2010-11-23 Allergan, Inc. Methods for treating mammary gland disorders
US7838008B2 (en) 1999-12-07 2010-11-23 Allergan, Inc. Methods for treating diverse cancers
DK1301213T3 (en) * 2000-07-21 2017-03-27 Revance Therapeutics Inc MULTI-COMPONENT SYSTEMS FOR BIOLOGICAL TRANSPORT
US7273722B2 (en) * 2000-11-29 2007-09-25 Allergan, Inc. Neurotoxins with enhanced target specificity
DK1399568T3 (da) * 2001-02-01 2006-03-27 Hoffmann La Roche Fremgangsmåde til fremstilling af rekombinant trypsin
US8071550B2 (en) * 2003-03-03 2011-12-06 Allergan, Inc. Methods for treating uterine disorders
US9211248B2 (en) 2004-03-03 2015-12-15 Revance Therapeutics, Inc. Compositions and methods for topical application and transdermal delivery of botulinum toxins
HUE025656T2 (en) 2004-03-03 2016-04-28 Revance Therapeutics Inc Topical application and transdermal delivery of botulinum toxins
BRPI0508440A (pt) 2004-03-03 2007-07-24 Revance Therapeutics Inc composições e métodos para diagnóstico tópico e transporte terapêutico
EP1570855A1 (fr) * 2004-03-04 2005-09-07 Claude Le Louarn Utilisation de toxine botulique pour préparer un médicament destiné à prévenir la pousse de poils
US7514088B2 (en) * 2005-03-15 2009-04-07 Allergan, Inc. Multivalent Clostridial toxin derivatives and methods of their use
US7811584B2 (en) 2004-06-30 2010-10-12 Allergan, Inc. Multivalent clostridial toxins
US7897147B2 (en) * 2004-10-20 2011-03-01 Allergan, Inc. Treatment of premenstrual disorders
JP4994241B2 (ja) * 2004-11-22 2012-08-08 ニューヨーク・ユニバーシティ 遺伝子操作されたクロストリジウム遺伝子、操作された遺伝子によりコードされるタンパク質、およびその使用
GB0426397D0 (en) 2004-12-01 2005-01-05 Health Prot Agency Fusion proteins
ES2362301T3 (es) 2005-03-03 2011-07-01 Revance Therapeutics, Inc. Composiciones y procedimientos para aplicaciones tópicas y liberación transdérmica de un oligopéptido.
KR20070110402A (ko) 2005-03-03 2007-11-16 레반스 테라퓨틱스 보툴리눔 독소의 국소 적용 및 경피 전달을 위한 조성물 및방법
US7419675B2 (en) * 2005-05-26 2008-09-02 Allergan, Inc. Method for treating peritoneal adhesions
DK2154151T3 (da) * 2005-09-19 2011-09-05 Allergan Inc Clostridiumtoksinaktiverbare clostridiumtoksiner
WO2007059528A2 (en) 2005-11-17 2007-05-24 Revance Therapeutics, Inc. Compositions and methods of topical application and transdermal delivery of botulinum toxins with reduced non-toxin proteins
EP2606911A1 (en) * 2007-02-16 2013-06-26 KTB Tumorforschungsgesellschaft mbH Receptor And Antigen Targeted Prodrug
JP5728380B2 (ja) * 2008-06-12 2015-06-03 シンタクシン リミテッドＳｙｎｔａｘｉｎ Ｌｉｍｉｔｅｄ 神経内分泌疾患の抑制
US8796216B2 (en) 2008-06-12 2014-08-05 Syntaxin Limited Suppression of neuroendocrine diseases
ES2426667T3 (es) * 2008-09-09 2013-10-24 Susanne Grafe Toxina botulínica para introducir infertilidad temporal en un vertebrado (por ejemplo, un ser humano)
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
GB0820970D0 (en) * 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
EP2649984A1 (en) 2012-04-13 2013-10-16 Lipotec, S.A. Compounds which inhibit neuronal exocytosis
ES2660901T3 (es) 2012-04-13 2018-03-26 Lubrizol Advanced Materials, Inc. Compuestos que inhiben la exocitosis neuronal (II)
EP2649983A1 (en) 2012-04-13 2013-10-16 Lipotec, S.A. Compounds which inhibit neuronal exocytosis (II)
EP2649985A1 (en) 2012-04-13 2013-10-16 Lipotec, S.A. Compounds which inhibit neuronal exocytosis (III)
WO2014117148A1 (en) 2013-01-28 2014-07-31 New York University Treatment methods using atoxic neurotoxin derivatives
US11897921B2 (en) 2014-12-09 2024-02-13 New York University Propeptide fusion comprising a mutated clostridium botulinum neurotoxin and a VHH domain
US20220211860A1 (en) * 2019-05-02 2022-07-07 The University Of Sydney Peptide derivatives and conjugates thereof for treating cancer
US11338016B2 (en) 2020-05-20 2022-05-24 Howard University C-terminal fragment of tetanus toxin (Hc) for treatment of depression
WO2022019583A1 (ko) * 2020-07-23 2022-01-27 (주)메디톡스 엑소좀-매개된 질환 치료제
KR102942184B1 (ko) * 2020-07-23 2026-03-20 (주)메디톡스 암 치료제

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WO1990009799A1 (en) 1989-02-23 1990-09-07 Colorado State University Research Foundation GnRH ANALOGS FOR DESTROYING GONADOTROPHS
US5264618A (en) 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
US6005086A (en) 1995-01-13 1999-12-21 The Salk Institute For Biological Studies Farnesoid activated receptor polypeptides, and nucleic acid encoding the same
GB9508204D0 (en) 1995-04-21 1995-06-07 Speywood Lab Ltd A novel agent able to modify peripheral afferent function
GB9617671D0 (en) 1996-08-23 1996-10-02 Microbiological Res Authority Recombinant toxin fragments
US5939070A (en) 1996-10-28 1999-08-17 Wisconsin Alumni Research Foundation Hybrid botulinal neurotoxins
GB9721189D0 (en) 1997-10-08 1997-12-03 Speywood Lab The Limited Analgesic conjugates
GB9907429D0 (en) 1999-03-31 1999-05-26 Microbiological Res Authority Modulation of C-fibre activity
US6139845A (en) 1999-12-07 2000-10-31 Allergan Sales, Inc. Method for treating cancer with a neurotoxin
US6827931B1 (en) 2000-10-20 2004-12-07 Allergan, Inc. Method for treating endocrine disorders

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